GREMLIN Database
DUF3352 - Protein of unknown function (DUF3352)
PFAM: PF11832 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 540 (518)
Sequences: 1085 (985)
Seq/√Len: 43.3
META: 0.735

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
162_Y200_D8.8081.00
42_V46_A6.0221.00
127_L198_A5.3751.00
189_A195_L5.0961.00
92_D95_K4.9861.00
445_A448_G4.8061.00
303_L307_T4.7191.00
412_T415_G4.3401.00
341_L353_D4.2581.00
268_E273_R4.0651.00
162_Y196_E4.0491.00
132_I138_A3.8831.00
313_G364_F3.7611.00
487_D490_K3.5091.00
100_W141_F3.3961.00
179_A199_I3.3871.00
345_K351_D3.3331.00
215_Y234_N3.2111.00
300_L469_F3.1901.00
351_D354_K3.0991.00
303_L367_A2.8351.00
298_K363_E2.8111.00
187_L198_A2.6831.00
132_I135_P2.6511.00
445_A451_L2.6451.00
303_L310_A2.6301.00
387_R391_E2.6171.00
218_A262_A2.6111.00
413_L418_V2.5401.00
42_V108_A2.4721.00
411_L420_A2.4721.00
135_P139_R2.3401.00
192_P196_E2.3181.00
165_V179_A2.3031.00
67_T70_D2.2781.00
167_I195_L2.2441.00
441_D447_S2.2161.00
467_P470_Q2.1821.00
42_V129_V2.1771.00
441_D448_G2.1731.00
165_V199_I2.1541.00
108_A127_L2.1491.00
480_N483_Y2.1491.00
398_D435_H2.1170.99
161_T166_T2.1140.99
305_A460_G2.1080.99
441_D445_A2.0990.99
94_E98_K2.0700.99
53_S56_P2.0260.99
129_V187_L2.0260.99
435_H439_D1.9840.99
93_Y98_K1.9630.99
100_W138_A1.9300.99
58_Q61_K1.8290.98
177_A180_V1.7890.98
436_G448_G1.7850.98
398_D421_W1.7690.98
162_Y199_I1.7680.98
179_A195_L1.7430.98
444_F448_G1.7400.98
384_T390_A1.7380.98
96_D99_P1.7380.98
6_V9_L1.7370.98
14_A18_W1.6660.97
444_F447_S1.6470.97
134_D137_K1.6440.97
378_G382_V1.6350.97
62_L108_A1.6320.97
10_G15_A1.6250.97
189_A205_G1.6060.96
398_D401_A1.6030.96
51_S104_E1.5870.96
511_K515_D1.5850.96
48_L231_A1.5810.96
510_A514_L1.5760.96
307_T463_L1.5660.96
359_W390_A1.5450.96
77_E80_Q1.5430.96
231_A263_A1.5390.95
527_S532_T1.5350.95
100_W132_I1.5340.95
4_A9_L1.5240.95
319_L324_L1.5150.95
42_V49_Y1.5100.95
4_A10_G1.5100.95
472_A521_G1.5040.95
161_T164_G1.4820.94
442_V445_A1.4810.94
367_A370_P1.4750.94
331_P334_A1.4710.94
477_P483_Y1.4710.94
93_Y99_P1.4670.94
355_D396_K1.4520.94
121_G157_L1.4510.94
468_A487_D1.4470.94
258_L266_G1.4430.94
167_I177_A1.4390.93
299_L312_S1.4320.93
360_M390_A1.4260.93
41_F185_F1.4180.93
65_F71_Q1.4170.93
201_T206_G1.4170.93
135_P184_D1.4130.93
451_L455_L1.4120.93
212_S234_N1.3940.92
508_L513_L1.3930.92
434_A437_W1.3900.92
463_L469_F1.3840.92
435_H444_F1.3820.92
209_L215_Y1.3810.92
391_E395_A1.3780.92
137_K140_A1.3750.92
51_S215_Y1.3750.92
88_D265_L1.3720.92
100_W134_D1.3670.92
96_D100_W1.3600.91
294_P464_A1.3540.91
362_G369_V1.3500.91
271_G477_P1.3480.91
168_I380_L1.3390.91
313_G316_L1.3370.91
441_D446_T1.3280.90
46_A66_G1.3260.90
187_L215_Y1.3220.90
41_F187_L1.3200.90
106_T111_P1.3190.90
20_L23_S1.3160.90
360_M382_V1.3120.90
158_E311_L1.3100.90
67_T72_A1.3050.90
63_R66_G1.3000.89
350_L356_L1.2970.89
137_K365_A1.2880.89
479_P482_G1.2830.89
223_P264_S1.2830.89
77_E83_D1.2810.89
5_A8_L1.2800.89
160_E196_E1.2790.89
8_L13_G1.2670.88
387_R390_A1.2600.88
169_S173_G1.2590.88
285_P291_A1.2590.88
468_A485_Y1.2590.88
303_L463_L1.2560.88
185_F443_V1.2530.88
183_D186_V1.2530.88
312_S457_A1.2510.87
186_V292_S1.2490.87
312_S480_N1.2490.87
348_L355_D1.2470.87
448_G456_A1.2440.87
57_D60_Q1.2410.87
341_L345_K1.2340.87
495_L522_V1.2310.87
103_G266_G1.2190.86
5_A9_L1.2180.86
132_I186_V1.2140.86
520_L528_D1.2140.86
343_Q346_S1.2120.86
79_D98_K1.2100.86
50_V107_L1.2060.85
239_A242_A1.2040.85
223_P227_L1.2000.85
161_T188_I1.1960.85
274_L297_S1.1950.85
496_E499_L1.1940.85
4_A15_A1.1920.85
101_L130_L1.1870.85
113_D125_G1.1820.84
80_Q83_D1.1810.84
272_L392_A1.1760.84
6_V10_G1.1750.84
528_D533_R1.1730.84
102_G355_D1.1600.83
505_L509_P1.1560.83
224_A264_S1.1550.83
476_L483_Y1.1530.83
265_L274_L1.1520.83
19_L22_Q1.1490.83
466_S485_Y1.1480.83
102_G131_A1.1470.82
392_A396_K1.1450.82
307_T367_A1.1360.82
78_L311_L1.1350.82
319_L405_G1.1330.82
93_Y467_P1.1320.82
41_F53_S1.1320.82
337_L340_L1.1290.81
66_G69_E1.1280.81
436_G441_D1.1240.81
163_K200_D1.1200.81
53_S58_Q1.1130.81
79_D82_R1.1110.80
59_W230_Q1.1090.80
242_A245_G1.1060.80
194_V365_A1.1040.80
226_R230_Q1.1040.80
381_V441_D1.1030.80
252_L470_Q1.0950.79
30_G315_N1.0930.79
186_V189_A1.0930.79
438_L455_L1.0900.79
199_I307_T1.0870.79
351_D355_D1.0790.78
3_A6_V1.0740.78
42_V215_Y1.0660.78
411_L418_V1.0580.77
52_L326_A1.0560.77
10_G20_L1.0550.77
62_L257_Q1.0490.76
96_D207_L1.0480.76
156_D159_R1.0460.76
299_L381_V1.0440.76
477_P480_N1.0430.76
512_P515_D1.0410.76
340_L343_Q1.0410.76
106_T109_V1.0400.76
410_P417_T1.0400.76
443_V447_S1.0380.76
452_A456_A1.0350.75
441_D444_F1.0340.75
130_L397_L1.0330.75
503_L509_P1.0270.75
340_L345_K1.0260.75
436_G444_F1.0250.75
177_A192_P1.0200.74
362_G436_G1.0100.74
296_A299_L1.0090.74
508_L520_L1.0070.73
52_L70_D1.0030.73
386_D390_A1.0030.73
103_G131_A1.0030.73
421_W424_P1.0000.73
307_T364_F0.9970.73
195_L337_L0.9960.73
418_V421_W0.9910.72
97_I501_P0.9890.72
144_K365_A0.9800.71
201_T356_L0.9790.71
453_A457_A0.9780.71
36_P49_Y0.9760.71
129_V201_T0.9760.71
9_L22_Q0.9710.71
477_P487_D0.9700.71
227_L397_L0.9700.71
43_P361_D0.9660.70
302_R357_L0.9650.70
447_S451_L0.9630.70
215_Y219_L0.9630.70
255_L258_L0.9620.70
56_P59_W0.9620.70
406_L421_W0.9620.70
290_L294_P0.9610.70
530_R533_R0.9580.70
447_S450_A0.9570.69
138_A189_A0.9560.69
238_A243_W0.9560.69
352_L355_D0.9530.69
90_G107_L0.9530.69
105_V254_Q0.9520.69
157_L160_E0.9510.69
507_E529_D0.9500.69
130_L465_D0.9490.69
16_A20_L0.9490.69
67_T71_Q0.9470.69
267_L419_T0.9460.69
3_A34_P0.9440.68
12_G17_Y0.9420.68
9_L14_A0.9390.68
359_W382_V0.9380.68
21_A473_I0.9340.68
134_D311_L0.9340.68
309_A487_D0.9340.68
17_Y23_S0.9300.67
365_A486_L0.9300.67
71_Q203_Q0.9260.67
361_D385_S0.9250.67
505_L515_D0.9210.67
435_H448_G0.9180.66
439_D443_V0.9170.66
46_A485_Y0.9150.66
75_D143_Q0.9140.66
130_L474_A0.9130.66
237_L485_Y0.9130.66
270_D350_L0.9120.66
86_L271_G0.9110.66
173_G430_A0.9110.66
134_D184_D0.9100.66
368_L486_L0.9090.65
97_I212_S0.9070.65
470_Q524_S0.9050.65
108_A231_A0.9040.65
451_L454_A0.9030.65
213_P515_D0.9030.65
465_D470_Q0.9020.65
501_P504_K0.9000.65
443_V485_Y0.8990.65
416_Q419_T0.8990.65
264_S523_T0.8980.65
177_A188_I0.8950.64
127_L194_V0.8950.64
17_Y20_L0.8940.64
7_V16_A0.8940.64
231_A368_L0.8930.64
14_A26_A0.8910.64
107_L522_V0.8900.64
134_D386_D0.8880.64
334_A338_D0.8820.63
311_L342_A0.8800.63
248_P252_L0.8800.63
320_W469_F0.8790.63
415_G420_A0.8780.63
181_V434_A0.8780.63
513_L516_A0.8750.62
113_D121_G0.8740.62
54_T59_W0.8730.62
495_L498_Q0.8690.62
132_I215_Y0.8680.62
85_L415_G0.8660.62
96_D144_K0.8650.62
80_Q398_D0.8640.62
307_T315_N0.8640.62
38_A127_L0.8620.61
93_Y219_L0.8610.61
477_P525_A0.8610.61
305_A426_G0.8610.61
52_L56_P0.8590.61
127_L187_L0.8580.61
435_H446_T0.8580.61
442_V448_G0.8580.61
187_L424_P0.8570.61
290_L293_E0.8560.61
345_K366_L0.8560.61
124_P323_L0.8550.61
229_A265_L0.8540.61
34_P440_G0.8520.60
138_A186_V0.8480.60
495_L499_L0.8470.60
164_G454_A0.8460.60
97_I406_L0.8430.60
496_E520_L0.8420.60
439_D469_F0.8410.59
241_A451_L0.8410.59
44_A207_L0.8370.59
369_V372_S0.8370.59
71_Q77_E0.8350.59
421_W426_G0.8330.59
41_F95_K0.8330.59
274_L469_F0.8300.58
107_L188_I0.8300.58
437_W444_F0.8280.58
323_L444_F0.8270.58
473_I476_L0.8240.58
488_V517_I0.8230.58
273_R477_P0.8190.57
46_A263_A0.8170.57
97_I265_L0.8170.57
43_P490_K0.8140.57
41_F51_S0.8130.57
345_K358_S0.8120.57
187_L205_G0.8110.57
91_L247_P0.8110.57
299_L309_A0.8100.57
359_W442_V0.8100.57
378_G488_V0.8090.56
282_W287_L0.8070.56
167_I196_E0.8060.56
307_T313_G0.8040.56
436_G445_A0.8010.56
408_V437_W0.8010.56
8_L113_D0.8000.56
97_I370_P0.7990.55
304_P315_N0.7990.55
51_S234_N0.7980.55
299_L360_M0.7950.55
268_E331_P0.7950.55
386_D389_A0.7940.55
15_A18_W0.7930.55
454_A457_A0.7920.55
124_P184_D0.7920.55
179_A187_L0.7900.55
211_D350_L0.7900.55
313_G335_Q0.7890.55
126_Y189_A0.7890.55
324_L328_A0.7890.55
387_R441_D0.7890.55
355_D358_S0.7860.54
502_A509_P0.7850.54
449_A452_A0.7850.54
189_A395_A0.7850.54
439_D448_G0.7840.54
376_P384_T0.7830.54
202_S230_Q0.7820.54
180_V367_A0.7780.54
312_S367_A0.7760.53
442_V451_L0.7760.53
4_A392_A0.7750.53
448_G452_A0.7750.53
16_A166_T0.7730.53
308_L314_G0.7730.53
507_E514_L0.7730.53
78_L92_D0.7730.53
185_F192_P0.7720.53
410_P415_G0.7710.53
95_K212_S0.7700.53
482_G487_D0.7700.53
336_L339_Q0.7700.53
360_M469_F0.7690.53
10_G13_G0.7690.53
98_K342_A0.7680.53
491_L495_L0.7680.53
467_P489_E0.7670.52
66_G70_D0.7650.52
66_G71_Q0.7640.52
55_D357_L0.7620.52
424_P444_F0.7610.52
491_L496_E0.7600.52
39_A290_L0.7590.52
472_A475_S0.7580.52
19_L23_S0.7570.52
18_W23_S0.7560.51
6_V15_A0.7560.51
508_L512_P0.7520.51
15_A20_L0.7520.51
412_T417_T0.7500.51
293_E306_D0.7480.51
29_A33_L0.7470.51
318_Q477_P0.7470.51
292_S464_A0.7460.50
146_K221_Q0.7460.50
36_P275_D0.7450.50
370_P524_S0.7450.50
108_A416_Q0.7440.50
16_A21_A0.7420.50
439_D445_A0.7380.50
246_S272_L0.7370.50
42_V142_L0.7350.49
518_R522_V0.7350.49
132_I180_V0.7340.49
3_A10_G0.7330.49
438_L445_A0.7320.49
446_T469_F0.7290.49
512_P517_I0.7280.49
255_L484_F0.7270.49
399_A462_S0.7260.49
352_L414_G0.7260.49
163_K199_I0.7250.48
399_A403_S0.7250.48
234_N349_G0.7230.48
259_Q277_A0.7230.48
178_T182_G0.7190.48
398_D485_Y0.7190.48
38_A198_A0.7180.48
487_D491_L0.7170.48
298_K301_S0.7170.48
129_V139_R0.7140.47
313_G324_L0.7140.47
505_L521_G0.7110.47
239_A245_G0.7100.47
434_A442_V0.7090.47
181_V300_L0.7080.47
189_A466_S0.7070.47
199_I478_S0.7060.47
3_A8_L0.7050.47
41_F201_T0.7040.46
91_L141_F0.7030.46
206_G440_G0.7030.46
407_S440_G0.7030.46
359_W385_S0.7030.46
201_T207_L0.7020.46
212_S232_Y0.7020.46
7_V23_S0.7020.46
418_V422_T0.7010.46
56_P60_Q0.7010.46
14_A22_Q0.7000.46
267_L272_L0.7000.46
168_I189_A0.7000.46
507_E522_V0.7000.46
14_A81_L0.6990.46
251_T265_L0.6980.46
462_S487_D0.6960.46
163_K385_S0.6960.46
256_Q273_R0.6950.46
10_G19_L0.6950.46
29_A32_S0.6940.46
108_A229_A0.6940.46
99_P304_P0.6930.45
257_Q260_G0.6920.45
38_A51_S0.6900.45
436_G439_D0.6900.45
492_L496_E0.6880.45
198_A201_T0.6880.45
142_L427_G0.6870.45
340_L348_L0.6860.45
113_D465_D0.6860.45
7_V375_G0.6850.45
355_D359_W0.6820.44
7_V10_G0.6810.44
140_A380_L0.6780.44
270_D325_A0.6780.44
254_Q259_Q0.6770.44
199_I385_S0.6760.44
437_W448_G0.6750.44
101_L366_L0.6750.44
271_G487_D0.6740.44
382_V385_S0.6730.44
73_A77_E0.6730.44
348_L419_T0.6720.43
401_A485_Y0.6710.43
339_Q484_F0.6700.43
167_I474_A0.6700.43
304_P307_T0.6700.43
51_S106_T0.6690.43
108_A260_G0.6690.43
323_L365_A0.6680.43
52_L55_D0.6660.43
470_Q517_I0.6650.43
134_D209_L0.6640.43
408_V413_L0.6620.43
7_V37_A0.6620.43
38_A167_I0.6600.42
509_P525_A0.6580.42
298_K383_E0.6560.42
95_K350_L0.6550.42
69_E73_A0.6550.42
476_L485_Y0.6550.42
240_L443_V0.6510.41
52_L58_Q0.6510.41
309_A364_F0.6500.41
445_A450_A0.6500.41
245_G517_I0.6500.41
506_A528_D0.6500.41
409_S422_T0.6500.41
83_D89_S0.6490.41
400_L403_S0.6490.41
8_L156_D0.6490.41
378_G446_T0.6490.41
501_P510_A0.6470.41
471_A474_A0.6470.41
238_A270_D0.6460.41
342_A454_A0.6460.41
189_A193_K0.6460.41
42_V234_N0.6440.41
103_G316_L0.6440.41
213_P217_A0.6430.41
17_Y22_Q0.6420.41
524_S531_T0.6400.40
8_L44_A0.6400.40
439_D447_S0.6400.40
83_D183_D0.6400.40
252_L257_Q0.6390.40
18_W22_Q0.6380.40
513_L525_A0.6380.40
158_E166_T0.6370.40
153_G323_L0.6370.40
266_G303_L0.6350.40
41_F54_T0.6340.40
105_V256_Q0.6340.40
299_L310_A0.6330.40
78_L101_L0.6320.40
323_L368_L0.6320.40
11_L14_A0.6310.40
362_G383_E0.6310.40
239_A436_G0.6310.40
261_L272_L0.6300.40
146_K153_G0.6300.40
4_A520_L0.6290.39
368_L391_E0.6280.39
359_W393_T0.6280.39
498_Q503_L0.6260.39
263_A356_L0.6260.39
492_L514_L0.6250.39
271_G435_H0.6250.39
97_I194_V0.6240.39
272_L404_Q0.6240.39
376_P379_V0.6230.39
509_P519_S0.6230.39
30_G33_L0.6220.39
414_G418_V0.6210.39
280_V283_L0.6210.39
498_Q521_G0.6210.39
12_G520_L0.6200.39
181_V411_L0.6200.39
139_R143_Q0.6190.39
125_G212_S0.6180.38
436_G447_S0.6180.38
240_L395_A0.6180.38
388_A392_A0.6180.38
145_L307_T0.6170.38
327_L417_T0.6160.38
340_L518_R0.6150.38
51_S54_T0.6140.38
68_P72_A0.6140.38
451_L456_A0.6140.38
189_A441_D0.6140.38
460_G466_S0.6130.38
104_E363_E0.6120.38
433_A438_L0.6120.38
446_T456_A0.6120.38
268_E472_A0.6110.38
217_A358_S0.6110.38
205_G464_A0.6090.38
504_K508_L0.6080.38
179_A182_G0.6080.38
350_L359_W0.6080.38
344_L348_L0.6070.37
95_K522_V0.6060.37
206_G349_G0.6060.37
313_G469_F0.6060.37
502_A511_K0.6040.37
135_P367_A0.6030.37
466_S470_Q0.6000.37
407_S436_G0.5990.37
12_G444_F0.5990.37
307_T341_L0.5990.37
50_V231_A0.5990.37
494_L498_Q0.5980.37
13_G20_L0.5980.37
88_D158_E0.5980.37
51_S267_L0.5970.37
110_L437_W0.5960.36
235_V478_S0.5960.36
29_A48_L0.5960.36
190_N422_T0.5950.36
107_L146_K0.5940.36
33_L344_L0.5930.36
38_A46_A0.5930.36
504_K512_P0.5930.36
319_L325_A0.5920.36
435_H442_V0.5920.36
93_Y100_W0.5920.36
512_P518_R0.5910.36
6_V461_N0.5910.36
226_R299_L0.5900.36
45_D60_Q0.5900.36
358_S376_P0.5900.36
320_W483_Y0.5900.36
460_G467_P0.5890.36
455_L477_P0.5890.36
236_P240_L0.5880.36
50_V133_K0.5860.36
142_L179_A0.5860.36
412_T425_Q0.5840.35
60_Q227_L0.5830.35
334_A429_L0.5810.35
52_L295_V0.5800.35
31_G35_P0.5800.35
217_A439_D0.5800.35
475_S521_G0.5780.35
401_A405_G0.5780.35
66_G72_A0.5770.35
312_S482_G0.5770.35
365_A370_P0.5770.35
92_D188_I0.5770.35
110_L113_D0.5760.35
152_A338_D0.5760.35
105_V321_Q0.5760.35
126_Y276_A0.5740.35
40_K352_L0.5730.34
6_V11_L0.5710.34
13_G23_S0.5710.34
57_D103_G0.5710.34
72_A414_G0.5700.34
501_P507_E0.5700.34
364_F448_G0.5680.34
167_I438_L0.5680.34
199_I203_Q0.5670.34
522_V527_S0.5670.34
115_D403_S0.5660.34
42_V198_A0.5650.34
64_Q167_I0.5650.34
421_W501_P0.5650.34
154_A170_G0.5650.34
103_G308_L0.5640.34
310_A365_A0.5640.34
356_L396_K0.5630.34
107_L305_A0.5620.34
444_F455_L0.5620.34
307_T450_A0.5620.34
137_K223_P0.5610.33
131_A359_W0.5610.33
200_D377_G0.5600.33
46_A49_Y0.5600.33
349_G386_D0.5600.33
519_S527_S0.5600.33
184_D492_L0.5600.33
63_R75_D0.5590.33
266_G273_R0.5590.33
216_Q345_K0.5580.33
420_A426_G0.5580.33
128_L407_S0.5570.33
7_V22_Q0.5570.33
20_L94_E0.5570.33
227_L369_V0.5560.33
93_Y235_V0.5550.33
187_L401_A0.5540.33
301_S306_D0.5530.33
394_L477_P0.5520.33
134_D330_N0.5510.33
109_V470_Q0.5510.33
306_D371_G0.5510.33
320_W364_F0.5490.32
124_P253_A0.5480.32
239_A243_W0.5480.32
45_D212_S0.5470.32
252_L337_L0.5470.32
499_L505_L0.5470.32
221_Q474_A0.5470.32
141_F476_L0.5460.32
310_A420_A0.5460.32
293_E361_D0.5450.32
136_A349_G0.5440.32
101_L133_K0.5440.32
415_G423_S0.5410.32
305_A373_G0.5410.32
463_L518_R0.5410.32
127_L263_A0.5400.32
284_D430_A0.5400.32
7_V15_A0.5390.32
163_K217_A0.5390.32
210_A264_S0.5380.32
515_D518_R0.5370.31
71_Q167_I0.5370.31
389_A406_L0.5340.31
140_A192_P0.5310.31
439_D442_V0.5310.31
97_I390_A0.5300.31
210_A352_L0.5290.31
467_P471_A0.5290.31
59_W131_A0.5280.31
423_S426_G0.5280.31
93_Y408_V0.5280.31
305_A334_A0.5270.31
59_W62_L0.5250.30
517_I520_L0.5250.30
193_K196_E0.5240.30
4_A7_V0.5240.30
143_Q256_Q0.5230.30
129_V135_P0.5220.30
397_L458_K0.5220.30
270_D351_D0.5210.30
293_E310_A0.5200.30
527_S531_T0.5200.30
129_V195_L0.5190.30
51_S209_L0.5180.30
54_T66_G0.5170.30
78_L439_D0.5170.30
402_A409_S0.5170.30
3_A407_S0.5170.30
123_Q195_L0.5170.30
478_S486_L0.5160.30
435_H483_Y0.5150.30
523_T526_G0.5150.30
272_L388_A0.5140.30
163_K414_G0.5140.30
63_R314_G0.5130.30
166_T307_T0.5120.29
19_L26_A0.5120.29
307_T310_A0.5120.29
118_A176_G0.5110.29
5_A312_S0.5110.29
425_Q428_P0.5110.29
213_P240_L0.5100.29
345_K484_F0.5090.29
260_G266_G0.5090.29
42_V138_A0.5090.29
137_K179_A0.5070.29
515_D526_G0.5060.29
503_L508_L0.5060.29
169_S520_L0.5050.29
287_L454_A0.5050.29
411_L424_P0.5040.29
53_S446_T0.5040.29
13_G16_A0.5020.29
198_A262_A0.5010.29
188_I452_A0.5010.29
264_S478_S0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1s7qA 1 0 12.1 0.972 Contact Map
4um9B 2 0 4.6 0.976 Contact Map
1spfA 1 0.0389 4.1 0.977 Contact Map
2q13A 2 0.1481 3.7 0.977 Contact Map
2lxtC 1 0.063 3.5 0.978 Contact Map
1jbwA 1 0.1111 3.1 0.978 Contact Map
3j1rA 5 0.0426 3 0.979 Contact Map
1kdxB 1 0.0519 2.9 0.979 Contact Map
2jwaA 2 0.0519 2.9 0.979 Contact Map
2ks1B 1 0.0537 2.5 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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