GREMLIN Database
PMD - Plant mobile domain
PFAM: PF10536 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 363 (361)
Sequences: 717 (520)
Seq/√Len: 27.4
META: 0.071

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
256_E262_T3.9821.00
207_P210_A3.8861.00
23_L185_A3.8721.00
338_Y341_P3.6661.00
207_P211_R3.5381.00
253_F259_D3.4691.00
335_W338_Y3.3471.00
253_F256_E3.3011.00
256_E259_D3.2661.00
40_E296_R3.2611.00
259_D262_T3.1481.00
274_F277_C3.1301.00
220_L224_R2.7781.00
253_F258_G2.6660.99
224_R227_L2.6480.99
256_E260_W2.6410.99
32_N162_H2.5650.99
226_F229_G2.5530.99
249_A252_R2.3940.99
334_A338_Y2.3370.99
209_A212_W2.2980.98
257_N262_T2.2420.98
253_F262_T2.2380.98
199_L202_N2.2000.98
42_T297_V2.1990.98
256_E261_V2.1230.97
252_R262_T2.1140.97
98_W103_F2.0850.97
225_K228_D2.0730.97
305_Q308_P2.0260.96
222_W227_L2.0120.96
249_A257_N2.0060.96
358_Y361_W2.0010.96
253_F257_N1.9530.96
253_F261_V1.9530.96
334_A337_D1.9140.95
176_G182_Q1.9080.95
184_W189_F1.8980.95
315_H320_R1.8860.95
337_D340_K1.8730.94
41_M235_F1.8660.94
327_W335_W1.8240.94
307_I310_P1.8040.93
318_D321_V1.8040.93
332_E335_W1.7990.93
210_A215_A1.7760.93
258_G261_V1.7640.92
42_T182_Q1.7580.92
177_P184_W1.7370.92
116_W138_A1.7230.91
335_W341_P1.6970.91
199_L203_S1.6940.91
337_D342_I1.6930.91
98_W102_F1.6740.90
253_F260_W1.6510.90
223_F227_L1.6460.89
25_E224_R1.6260.89
23_L43_I1.6160.88
117_L138_A1.6140.88
200_A203_S1.5880.88
184_W188_R1.5840.87
331_H335_W1.5730.87
331_H334_A1.5600.87
273_S278_L1.5460.86
335_W340_K1.5280.85
73_V76_K1.5270.85
263_Y268_P1.5250.85
224_R228_D1.5210.85
2_I9_S1.5170.85
34_F44_T1.5140.85
316_L322_D1.5130.85
207_P212_W1.5130.85
97_A101_Q1.5110.85
313_L316_L1.5080.85
257_N260_W1.5010.84
190_P193_R1.5000.84
337_D341_P1.4980.84
98_W111_A1.4840.84
313_L317_T1.4830.84
257_N261_V1.4820.84
316_L320_R1.4750.83
222_W229_G1.4700.83
74_C80_V1.4390.82
225_K229_G1.4260.81
358_Y362_W1.4120.80
250_L256_E1.4070.80
196_F202_N1.4030.80
220_L226_F1.3910.79
185_A189_F1.3860.79
270_E273_S1.3850.79
148_A151_P1.3780.79
33_T40_E1.3740.79
315_H321_V1.3700.78
273_S276_R1.3520.77
273_S277_C1.3520.77
222_W226_F1.3480.77
197_P202_N1.3310.76
306_D309_G1.3300.76
265_I268_P1.3290.76
52_L177_P1.3280.76
209_A213_G1.3260.76
314_H317_T1.3250.76
39_G42_T1.3220.76
308_P361_W1.3080.75
314_H320_R1.3000.75
325_A328_S1.2950.74
254_Y261_V1.2940.74
76_K79_G1.2770.73
187_E193_R1.2770.73
236_I245_L1.2740.73
138_A144_G1.2640.72
258_G262_T1.2630.72
3_Y7_S1.2620.72
116_W120_F1.2620.72
61_V152_A1.2550.72
211_R214_Q1.2530.72
186_W193_R1.2520.72
83_E86_L1.2440.71
210_A213_G1.2380.71
109_H141_L1.2380.71
94_N98_W1.2330.71
212_W239_P1.2330.71
114_L135_L1.2310.70
2_I6_I1.2230.70
299_R305_Q1.2190.70
47_D188_R1.2160.69
255_D262_T1.2120.69
250_L253_F1.2120.69
326_D331_H1.2050.69
252_R256_E1.2040.69
213_G216_K1.2030.69
196_F199_L1.1980.68
31_T40_E1.1850.67
329_Q353_S1.1710.67
207_P217_S1.1680.66
112_F116_W1.1660.66
41_M188_R1.1600.66
319_R324_D1.1570.66
250_L257_N1.1490.65
235_F238_R1.1460.65
116_W144_G1.1380.64
209_A215_A1.1380.64
197_P203_S1.1360.64
27_W158_Y1.1360.64
123_P153_V1.1340.64
187_E212_W1.1340.64
264_S267_L1.1270.63
214_Q217_S1.1270.63
330_R335_W1.1250.63
336_S339_N1.1240.63
307_I311_V1.1230.63
209_A214_Q1.1220.63
263_Y267_L1.1170.63
42_T45_L1.1170.63
144_G149_L1.1130.62
212_W216_K1.1130.62
111_A302_G1.1110.62
249_A259_D1.1030.62
177_P183_L1.1000.62
329_Q337_D1.0960.61
251_F256_E1.0940.61
207_P213_G1.0920.61
26_F228_D1.0850.60
8_L13_I1.0830.60
349_L353_S1.0680.59
46_E188_R1.0640.59
112_F120_F1.0630.59
336_S340_K1.0530.58
183_L186_W1.0520.58
193_R196_F1.0510.58
95_W98_W1.0510.58
27_W305_Q1.0510.58
94_N101_Q1.0490.58
282_N286_F1.0470.58
25_E40_E1.0470.58
208_R211_R1.0430.57
25_E31_T1.0410.57
113_L141_L1.0260.56
6_I9_S1.0190.56
327_W334_A1.0170.55
49_A157_L1.0140.55
250_L259_D1.0110.55
225_K237_W0.9980.54
250_L260_W0.9980.54
274_F278_L0.9950.54
44_T297_V0.9930.54
276_R279_R0.9930.54
264_S268_P0.9890.53
80_V83_E0.9880.53
195_N199_L0.9810.53
207_P214_Q0.9790.53
26_F35_H0.9760.52
249_A256_E0.9720.52
329_Q332_E0.9720.52
320_R323_P0.9700.52
123_P173_R0.9680.52
186_W212_W0.9670.52
47_D51_L0.9640.51
182_Q186_W0.9630.51
262_T267_L0.9620.51
250_L262_T0.9520.51
77_L80_V0.9510.50
47_D158_Y0.9430.50
179_W183_L0.9420.50
334_A355_T0.9380.49
7_S12_P0.9370.49
223_F226_F0.9330.49
263_Y266_M0.9240.48
327_W331_H0.9220.48
7_S11_Y0.9210.48
334_A341_P0.9170.48
255_D261_V0.9160.48
271_L274_F0.9150.48
313_L320_R0.9100.47
90_A97_A0.9070.47
96_S104_K0.9070.47
208_R213_G0.9020.47
184_W194_P0.9010.47
236_I301_F0.8990.47
324_D329_Q0.8940.46
325_A329_Q0.8930.46
317_T322_D0.8910.46
261_V265_I0.8900.46
178_L181_L0.8900.46
232_P235_F0.8890.46
16_D157_L0.8870.46
251_F255_D0.8870.46
96_S103_F0.8860.46
99_L103_F0.8850.45
345_Y352_T0.8820.45
334_A340_K0.8810.45
40_E45_L0.8780.45
333_S340_K0.8740.45
319_R326_D0.8720.44
235_F239_P0.8710.44
333_S338_Y0.8700.44
261_V264_S0.8670.44
282_N291_F0.8660.44
248_W251_F0.8640.44
249_A261_V0.8590.44
252_R259_D0.8550.43
230_L235_F0.8540.43
211_R215_A0.8520.43
25_E43_I0.8510.43
136_P143_R0.8500.43
228_D237_W0.8480.43
94_N99_L0.8460.43
26_F40_E0.8450.42
116_W362_W0.8440.42
251_F254_Y0.8410.42
315_H318_D0.8400.42
210_A214_Q0.8380.42
277_C283_L0.8370.42
117_L144_G0.8360.42
109_H113_L0.8350.42
313_L318_D0.8340.42
249_A260_W0.8300.41
329_Q349_L0.8300.41
3_Y12_P0.8280.41
280_T285_G0.8260.41
54_L299_R0.8260.41
350_S353_S0.8260.41
282_N285_G0.8250.41
28_S36_F0.8230.41
80_V84_L0.8220.41
78_L81_R0.8210.41
258_G267_L0.8200.41
330_R338_Y0.8190.41
345_Y349_L0.8180.40
243_S246_F0.8170.40
94_N103_F0.8140.40
335_W342_I0.8140.40
350_S356_V0.8140.40
331_H337_D0.8140.40
51_L273_S0.8100.40
73_V80_V0.8060.40
59_S157_L0.8050.40
313_L322_D0.8040.39
251_F259_D0.8010.39
186_W194_P0.7920.39
57_S137_L0.7910.39
138_A149_L0.7890.38
116_W149_L0.7860.38
334_A342_I0.7840.38
10_L13_I0.7830.38
336_S357_D0.7800.38
208_R212_W0.7790.38
27_W34_F0.7790.38
324_D347_P0.7770.38
34_F39_G0.7760.37
3_Y6_I0.7760.37
126_S135_L0.7750.37
26_F34_F0.7750.37
252_R257_N0.7710.37
331_H338_Y0.7700.37
113_L116_W0.7630.37
3_Y8_L0.7630.37
254_Y260_W0.7630.37
250_L258_G0.7610.36
188_R193_R0.7610.36
84_L87_S0.7540.36
32_N163_L0.7480.35
347_P351_E0.7480.35
138_A142_A0.7480.35
151_P162_H0.7470.35
313_L319_R0.7410.35
339_N350_S0.7400.35
134_Y150_G0.7400.35
300_Q305_Q0.7390.35
250_L261_V0.7380.35
120_F153_V0.7380.35
19_L185_A0.7370.35
157_L311_V0.7350.35
11_Y20_L0.7350.35
95_W103_F0.7350.35
330_R334_A0.7330.34
212_W240_Y0.7320.34
184_W187_E0.7300.34
349_L356_V0.7300.34
125_P171_K0.7270.34
227_L231_S0.7270.34
353_S359_M0.7260.34
329_Q334_A0.7250.34
2_I5_A0.7250.34
193_R197_P0.7240.34
97_A165_S0.7240.34
94_N97_A0.7240.34
208_R219_K0.7230.34
314_H318_D0.7230.34
335_W345_Y0.7230.34
113_L274_F0.7210.34
255_D268_P0.7190.34
210_A217_S0.7180.33
53_G290_E0.7170.33
281_S285_G0.7150.33
222_W225_K0.7110.33
332_E340_K0.7100.33
109_H116_W0.7100.33
118_G130_V0.7090.33
133_N286_F0.7090.33
316_L319_R0.7080.33
181_L187_E0.7060.33
318_D322_D0.7050.33
236_I242_D0.7040.32
345_Y348_R0.7040.32
60_P121_L0.7030.32
7_S13_I0.7010.32
270_E274_F0.7000.32
213_G217_S0.6990.32
112_F294_P0.6990.32
8_L12_P0.6960.32
207_P216_K0.6940.32
332_E336_S0.6910.32
193_R199_L0.6900.32
96_S99_L0.6900.32
183_L188_R0.6900.32
277_C282_N0.6890.32
147_Y228_D0.6890.32
52_L179_W0.6880.31
109_H138_A0.6840.31
74_C79_G0.6840.31
350_S360_E0.6830.31
336_S344_L0.6820.31
39_G158_Y0.6810.31
108_E177_P0.6810.31
87_S91_G0.6800.31
306_D310_P0.6790.31
55_P304_D0.6790.31
208_R302_G0.6790.31
197_P200_A0.6780.31
27_W44_T0.6750.31
168_L227_L0.6750.31
5_A9_S0.6730.30
8_L11_Y0.6670.30
341_P344_L0.6620.30
121_L138_A0.6610.30
224_R229_G0.6610.30
290_E300_Q0.6580.30
150_G277_C0.6570.29
185_A191_V0.6560.29
322_D333_S0.6540.29
259_D263_Y0.6540.29
121_L318_D0.6540.29
228_D231_S0.6530.29
44_T300_Q0.6520.29
338_Y342_I0.6520.29
39_G47_D0.6470.29
349_L352_T0.6450.29
136_P192_L0.6440.29
255_D259_D0.6440.29
339_N342_I0.6420.29
31_T37_P0.6400.28
321_V328_S0.6400.28
222_W228_D0.6390.28
26_F31_T0.6380.28
152_A174_L0.6360.28
348_R354_V0.6340.28
324_D327_W0.6330.28
140_D145_G0.6290.28
315_H319_R0.6270.28
348_R353_S0.6270.28
123_P171_K0.6270.28
191_V201_E0.6260.28
307_I359_M0.6240.27
332_E337_D0.6220.27
251_F261_V0.6210.27
252_R255_D0.6200.27
223_F235_F0.6200.27
249_A262_T0.6190.27
336_S341_P0.6180.27
184_W193_R0.6180.27
327_W332_E0.6140.27
243_S247_E0.6100.27
332_E338_Y0.6090.27
19_L27_W0.6060.26
265_I270_E0.6020.26
255_D263_Y0.6010.26
319_R327_W0.6000.26
74_C78_L0.5990.26
205_G209_A0.5990.26
76_K106_K0.5980.26
331_H341_P0.5970.26
16_D19_L0.5950.26
251_F257_N0.5940.26
16_D27_W0.5940.26
272_L275_A0.5930.26
273_S279_R0.5920.26
52_L98_W0.5920.26
75_E81_R0.5920.26
97_A100_N0.5910.25
183_L189_F0.5910.25
43_I180_L0.5900.25
25_E30_E0.5900.25
51_L187_E0.5890.25
226_F235_F0.5890.25
268_P273_S0.5890.25
110_R114_L0.5880.25
7_S10_L0.5860.25
281_S284_I0.5860.25
342_I356_V0.5850.25
237_W240_Y0.5850.25
250_L254_Y0.5830.25
254_Y259_D0.5830.25
157_L249_A0.5820.25
117_L121_L0.5810.25
325_A333_S0.5810.25
76_K84_L0.5800.25
158_Y194_P0.5800.25
135_L150_G0.5790.25
255_D264_S0.5790.25
76_K81_R0.5780.25
20_L174_L0.5780.25
204_G215_A0.5780.25
47_D154_L0.5770.25
109_H123_P0.5770.25
314_H322_D0.5760.25
30_E40_E0.5710.24
330_R340_K0.5700.24
319_R322_D0.5690.24
194_P203_S0.5680.24
25_E28_S0.5680.24
93_T96_S0.5670.24
320_R324_D0.5650.24
36_F108_E0.5640.24
330_R337_D0.5640.24
209_A217_S0.5620.24
110_R142_A0.5620.24
112_F177_P0.5610.24
56_I263_Y0.5610.24
194_P283_L0.5600.24
196_F203_S0.5590.24
27_W308_P0.5580.24
254_Y257_N0.5570.24
237_W249_A0.5560.24
307_I321_V0.5560.24
41_M192_L0.5530.23
53_G184_W0.5530.23
208_R216_K0.5530.23
283_L286_F0.5520.23
212_W215_A0.5520.23
349_L360_E0.5510.23
110_R149_L0.5510.23
246_F251_F0.5510.23
257_N265_I0.5500.23
262_T265_I0.5500.23
37_P40_E0.5500.23
316_L321_V0.5490.23
280_T283_L0.5470.23
239_P254_Y0.5450.23
277_C280_T0.5450.23
179_W298_A0.5430.23
182_Q297_V0.5410.23
96_S101_Q0.5410.23
83_E88_K0.5400.23
131_K177_P0.5400.23
327_W343_D0.5400.23
179_W188_R0.5400.23
335_W339_N0.5390.23
330_R333_S0.5390.23
267_L278_L0.5370.22
347_P353_S0.5370.22
278_L282_N0.5360.22
245_L248_W0.5340.22
252_R261_V0.5330.22
341_P349_L0.5330.22
319_R355_T0.5320.22
127_G189_F0.5290.22
189_F192_L0.5290.22
220_L231_S0.5280.22
34_F42_T0.5280.22
248_W253_F0.5280.22
53_G177_P0.5270.22
79_G82_P0.5270.22
221_E242_D0.5270.22
4_D9_S0.5260.22
332_E339_N0.5260.22
23_L139_Y0.5260.22
326_D338_Y0.5250.22
326_D335_W0.5240.22
4_D7_S0.5200.22
120_F149_L0.5180.21
94_N104_K0.5160.21
204_G208_R0.5150.21
197_P201_E0.5150.21
68_S80_V0.5140.21
58_G148_A0.5140.21
113_L193_R0.5120.21
251_F262_T0.5120.21
249_A253_F0.5110.21
267_L273_S0.5100.21
23_L46_E0.5090.21
190_P196_F0.5080.21
220_L225_K0.5060.21
255_D258_G0.5060.21
272_L279_R0.5050.21
137_L215_A0.5040.21
148_A162_H0.5030.21
33_T58_G0.5020.21
186_W283_L0.5010.21
21_K24_V0.5010.21
254_Y262_T0.5000.21
307_I318_D0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4gl3A 1 0.1708 8.3 0.974 Contact Map
4r8oA 2 0.124 6.3 0.975 Contact Map
4ix1A 2 0.1983 5.9 0.976 Contact Map
4akgA 2 0.2314 5 0.977 Contact Map
4u2vB 2 0.4435 4.5 0.977 Contact Map
4or5E 1 0.1047 4.3 0.977 Contact Map
1xdxA 2 0.1488 4.2 0.977 Contact Map
3d8lA 2 0.0854 4.2 0.977 Contact Map
2dgdA 4 0.2094 3.8 0.978 Contact Map
1ygtA 2 0.1515 3 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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