GREMLIN Database
DM13 - Electron transfer DM13
PFAM: PF10517 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 103 (96)
Sequences: 9115 (5764)
Seq/√Len: 588.3
META: 0.885

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_H59_D3.5441.00
9_T99_G3.3521.00
36_H92_E2.9951.00
27_S67_K2.5491.00
20_V72_E2.4181.00
36_H62_P2.3171.00
80_D83_D2.2701.00
14_T24_E2.2311.00
97_L100_A2.1411.00
91_C94_F1.8701.00
41_P83_D1.8421.00
33_P94_F1.8001.00
32_G98_F1.7541.00
35_L98_F1.7151.00
88_V97_L1.6371.00
9_T28_T1.6221.00
34_D92_E1.5291.00
59_D92_E1.5211.00
10_S27_S1.5181.00
16_Y22_R1.5121.00
58_V79_V1.5111.00
40_S88_V1.4961.00
37_V89_I1.4961.00
33_P91_C1.4821.00
32_G35_L1.4761.00
39_L84_Y1.4601.00
12_T24_E1.4571.00
23_L26_F1.4231.00
41_P56_G1.3921.00
21_L87_V1.3811.00
90_W97_L1.3771.00
14_T22_R1.3611.00
34_D93_R1.3491.00
8_W30_S1.3461.00
90_W95_S1.3261.00
92_E95_S1.3091.00
23_L37_V1.2861.00
19_R81_L1.2441.00
25_D69_D1.2381.00
38_Y57_F1.2131.00
40_S86_S1.2071.00
37_V87_V1.1971.00
58_V84_Y1.1561.00
24_E69_D1.1001.00
43_P86_S1.0681.00
21_L73_I1.0471.00
28_T99_G1.0061.00
35_L89_I1.0031.00
12_T25_D0.9941.00
59_D62_P0.9901.00
88_V100_A0.9771.00
31_N66_N0.9361.00
25_D68_G0.9231.00
22_R69_D0.9071.00
49_G52_V0.8851.00
28_T35_L0.8711.00
5_D100_A0.8501.00
79_V84_Y0.8491.00
41_P85_R0.8411.00
31_N35_L0.8401.00
42_A85_R0.8311.00
73_I79_V0.8291.00
33_P93_R0.8241.00
13_A87_V0.7931.00
6_A96_V0.7911.00
36_H93_R0.7881.00
5_D8_W0.7881.00
62_P92_E0.7801.00
43_P85_R0.7801.00
40_S57_F0.7751.00
86_S102_P0.7741.00
16_Y19_R0.7731.00
17_E20_V0.7651.00
39_L87_V0.7621.00
39_L79_V0.7551.00
7_H32_G0.7541.00
38_Y90_W0.7481.00
5_D97_L0.7421.00
50_F53_K0.7341.00
63_L70_Q0.7311.00
47_G51_T0.7271.00
49_G53_K0.7231.00
23_L68_G0.7101.00
48_D51_T0.7091.00
8_W27_S0.7081.00
65_G70_Q0.7071.00
30_S99_G0.7001.00
7_H30_S0.6981.00
30_S66_N0.6951.00
16_Y20_V0.6941.00
7_H96_V0.6931.00
41_P84_Y0.6861.00
76_P79_V0.6861.00
68_G71_Y0.6841.00
34_D62_P0.6811.00
37_V63_L0.6801.00
97_L102_P0.6741.00
64_K71_Y0.6731.00
19_R79_V0.6711.00
35_L63_L0.6691.00
32_G94_F0.6601.00
73_I81_L0.6571.00
58_V78_G0.6561.00
44_D102_P0.6491.00
28_T98_F0.6461.00
23_L89_I0.6441.00
26_F69_D0.6351.00
66_N70_Q0.6331.00
94_F98_F0.6261.00
47_G96_V0.6201.00
22_R25_D0.6131.00
26_F89_I0.6101.00
40_S85_R0.6051.00
46_T49_G0.6021.00
42_A51_T0.5961.00
32_G91_C0.5941.00
47_G50_F0.5931.00
38_Y88_V0.5911.00
19_R72_E0.5851.00
31_N67_K0.5771.00
15_I19_R0.5661.00
79_V83_D0.5651.00
7_H94_F0.5641.00
20_V24_E0.5550.99
22_R72_E0.5450.99
64_K70_Q0.5450.99
9_T89_I0.5430.99
93_R96_V0.5420.99
52_V88_V0.5420.99
28_T66_N0.5410.99
90_W96_V0.5410.99
27_S68_G0.5400.99
45_P49_G0.5340.99
81_L84_Y0.5300.99
99_G102_P0.5290.99
63_L68_G0.5280.99
87_V101_A0.5240.99
19_R78_G0.5210.99
38_Y92_E0.5190.99
6_A30_S0.5180.99
86_S100_A0.5140.99
27_S30_S0.5130.99
53_K57_F0.5010.99
42_A45_P0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ueyA 1 0.5437 21.6 0.881 Contact Map
4q6kA 4 0.6893 7.8 0.903 Contact Map
2f68X 1 0.7476 6.3 0.907 Contact Map
2cclA 1 0.4369 6.2 0.907 Contact Map
2ygoA 2 0.6796 6 0.908 Contact Map
2ljkA 1 0.4175 5.1 0.911 Contact Map
4uypA 2 0.4369 4.2 0.914 Contact Map
3kwuA 1 0.7573 3.8 0.916 Contact Map
2ygnA 2 0.6796 3.8 0.916 Contact Map
4j1vA 1 0.3398 3.7 0.916 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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