Mu-like_Pro - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Mu-like_Pro - Mu-like prophage I protein

PFAM:	PF10123	Sequences: IQLLPAGEFRGRDGRPPDVPWRLDDESAAAVIAAFAARGNDLVIDYEHQTLLAAPNGQPAPAAGWIKELEWREGDGLWARVEWTPRAAAAIAAKEYRYISPVFLYDKKTGRVLRLLSAALTNTPALDGLDPLAALAAAELAETEEEEEEMEELLKALLAALGLPEDATEEEILAALTALKAAAAAVAAALGLAADADLAAAAAAVAALKAAAPDPAKFVPVATVTALQAELAALKAELAEAEAEALVDAALKDGKITPAQKDWARALAKKDLAAFKAFLAAAPPIAALGGTQTGGKAPGGPAATGAAALSAEELAVCKALGLSPEDFAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	329 (320)
Sequences:	1738 (1532)
Seq/√Len:	85.6
META:	0.741

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
230_E	235_K	5.455	1.00
261_K	265_R	3.753	1.00
168_T	171_E	3.630	1.00
323_S	326_D	3.545	1.00
68_E	80_R	3.356	1.00
224_V	227_L	3.352	1.00
249_A	253_D	3.118	1.00
89_A	93_A	3.055	1.00
314_L	324_P	3.017	1.00
106_D	109_T	2.997	1.00
99_I	118_A	2.745	1.00
11_G	125_A	2.716	1.00
72_R	78_W	2.701	1.00
86_R	95_E	2.690	1.00
227_L	231_L	2.550	1.00
158_L	172_I	2.471	1.00
43_V	50_T	2.411	1.00
75_D	78_W	2.375	1.00
24_D	111_R	2.345	1.00
154_L	169_E	2.304	1.00
82_E	94_K	2.274	1.00
88_A	92_A	2.243	1.00
87_A	91_I	2.236	1.00
267_L	274_A	2.235	1.00
223_T	228_Q	2.192	1.00
46_Y	63_A	2.152	1.00
324_P	328_A	2.139	1.00
41_D	67_K	2.053	1.00
242_E	276_K	2.021	1.00
51_L	117_S	2.003	1.00
46_Y	87_A	1.977	1.00
106_D	111_R	1.964	1.00
241_A	245_A	1.956	1.00
155_K	165_E	1.932	1.00
85_P	93_A	1.905	1.00
46_Y	95_E	1.889	1.00
41_D	98_Y	1.882	1.00
260_Q	282_A	1.860	1.00
29_A	33_A	1.853	1.00
278_F	282_A	1.835	1.00
273_A	276_K	1.835	1.00
176_L	179_L	1.806	1.00
232_A	236_A	1.805	1.00
244_E	265_R	1.782	1.00
221_V	225_T	1.760	1.00
67_K	82_E	1.757	1.00
41_D	97_R	1.738	1.00
316_V	319_A	1.699	1.00
315_A	319_A	1.677	1.00
3_L	118_A	1.676	1.00
28_A	32_I	1.655	1.00
310_S	313_E	1.653	1.00
175_A	178_A	1.641	1.00
6_A	71_W	1.622	1.00
256_I	264_A	1.610	1.00
90_A	95_E	1.603	1.00
86_R	90_A	1.578	1.00
102_V	117_S	1.574	1.00
24_D	27_S	1.574	1.00
262_D	266_A	1.548	1.00
248_D	261_K	1.533	1.00
251_L	261_K	1.527	1.00
2_Q	129_L	1.523	1.00
240_E	269_K	1.496	0.99
255_K	284_P	1.496	0.99
243_A	268_A	1.489	0.99
62_A	65_W	1.488	0.99
70_E	78_W	1.476	0.99
155_K	158_L	1.462	0.99
50_T	60_A	1.460	0.99
231_L	234_L	1.442	0.99
154_L	158_L	1.442	0.99
85_P	88_A	1.435	0.99
166_D	171_E	1.432	0.99
313_E	317_C	1.428	0.99
275_F	279_L	1.398	0.99
322_L	327_F	1.393	0.99
276_K	280_A	1.390	0.99
160_A	173_L	1.385	0.99
214_D	217_K	1.383	0.99
237_E	242_E	1.358	0.99
8_E	22_R	1.357	0.99
66_I	79_A	1.355	0.99
22_R	111_R	1.354	0.99
325_E	328_A	1.346	0.99
257_T	260_Q	1.339	0.99
213_P	218_F	1.325	0.99
23_L	28_A	1.314	0.99
197_D	200_A	1.307	0.99
286_A	289_G	1.304	0.99
277_A	280_A	1.297	0.99
49_Q	56_N	1.292	0.98
250_A	279_L	1.286	0.98
25_D	29_A	1.282	0.98
85_P	89_A	1.270	0.98
87_A	90_A	1.262	0.98
322_L	326_D	1.256	0.98
34_A	114_R	1.251	0.98
65_W	97_R	1.248	0.98
319_A	322_L	1.243	0.98
315_A	318_K	1.237	0.98
226_A	230_E	1.234	0.98
248_D	252_K	1.232	0.98
247_V	265_R	1.224	0.98
316_V	320_L	1.221	0.98
66_I	118_A	1.218	0.98
53_A	58_Q	1.215	0.98
240_E	244_E	1.213	0.98
223_T	226_A	1.204	0.98
271_D	274_A	1.199	0.98
77_L	115_L	1.195	0.97
313_E	327_F	1.193	0.97
72_R	75_D	1.193	0.97
249_A	252_K	1.183	0.97
317_C	324_P	1.183	0.97
46_Y	90_A	1.177	0.97
87_A	95_E	1.175	0.97
317_C	327_F	1.175	0.97
244_E	248_D	1.174	0.97
61_P	96_Y	1.164	0.97
36_A	68_E	1.163	0.97
224_V	228_Q	1.158	0.97
163_L	167_A	1.153	0.97
50_T	117_S	1.143	0.97
177_T	181_A	1.142	0.97
225_T	228_Q	1.137	0.97
236_A	240_E	1.135	0.97
187_A	190_L	1.130	0.96
117_S	123_T	1.104	0.96
44_I	99_I	1.099	0.96
201_A	204_A	1.099	0.96
63_A	87_A	1.097	0.96
56_N	59_P	1.097	0.96
41_D	82_E	1.086	0.96
273_A	277_A	1.085	0.95
264_A	267_L	1.072	0.95
239_A	243_A	1.071	0.95
215_P	218_F	1.067	0.95
25_D	73_E	1.066	0.95
196_A	201_A	1.066	0.95
272_L	276_K	1.064	0.95
49_Q	60_A	1.064	0.95
59_P	86_R	1.064	0.95
32_I	69_L	1.061	0.95
131_P	135_L	1.061	0.95
59_P	90_A	1.055	0.95
91_I	133_A	1.053	0.95
63_A	95_E	1.051	0.95
202_A	205_V	1.050	0.95
219_V	224_V	1.041	0.94
67_K	80_R	1.040	0.94
28_A	77_L	1.036	0.94
225_T	229_A	1.035	0.94
192_L	197_D	1.032	0.94
3_L	79_A	1.031	0.94
263_W	278_F	1.026	0.94
157_L	176_L	1.024	0.94
43_V	117_S	1.023	0.94
49_Q	61_P	1.023	0.94
313_E	316_V	1.018	0.94
47_E	90_A	1.006	0.93
11_G	17_P	1.004	0.93
264_A	275_F	1.000	0.93
157_L	160_A	0.983	0.92
260_Q	263_W	0.983	0.92
64_G	91_I	0.980	0.92
23_L	27_S	0.979	0.92
247_V	251_L	0.979	0.92
156_A	169_E	0.979	0.92
228_Q	232_A	0.979	0.92
317_C	328_A	0.979	0.92
64_G	81_V	0.973	0.92
86_R	89_A	0.970	0.92
314_L	317_C	0.969	0.92
167_A	172_I	0.967	0.92
10_R	16_P	0.967	0.92
260_Q	264_A	0.963	0.92
263_W	267_L	0.955	0.91
49_Q	58_Q	0.955	0.91
262_D	265_R	0.955	0.91
246_L	276_K	0.954	0.91
200_A	203_A	0.953	0.91
314_L	318_K	0.945	0.91
320_L	327_F	0.942	0.91
238_L	241_A	0.939	0.91
84_T	95_E	0.939	0.91
230_E	233_A	0.937	0.91
134_A	137_A	0.929	0.90
309_L	327_F	0.929	0.90
186_V	190_L	0.926	0.90
31_V	112_V	0.923	0.90
2_Q	78_W	0.923	0.90
69_L	115_L	0.915	0.89
30_A	33_A	0.913	0.89
103_F	114_R	0.913	0.89
264_A	278_F	0.911	0.89
245_A	248_D	0.908	0.89
243_A	247_V	0.906	0.89
201_A	205_V	0.906	0.89
51_L	116_L	0.904	0.89
44_I	118_A	0.900	0.89
51_L	102_V	0.899	0.89
229_A	233_A	0.898	0.89
222_A	226_A	0.893	0.88
267_L	278_F	0.883	0.88
198_L	201_A	0.880	0.88
9_F	110_G	0.880	0.88
9_F	23_L	0.876	0.87
231_L	235_K	0.873	0.87
217_K	222_A	0.872	0.87
245_A	249_A	0.871	0.87
246_L	279_L	0.868	0.87
143_T	146_E	0.865	0.87
43_V	47_E	0.865	0.87
169_E	172_I	0.857	0.86
199_A	203_A	0.855	0.86
192_L	201_A	0.855	0.86
50_T	61_P	0.851	0.86
47_E	61_P	0.842	0.85
231_L	238_L	0.839	0.85
176_L	180_K	0.837	0.85
309_L	313_E	0.836	0.85
142_E	145_E	0.836	0.85
61_P	95_E	0.835	0.85
308_A	317_C	0.835	0.85
29_A	71_W	0.834	0.85
35_F	42_L	0.832	0.84
318_K	324_P	0.831	0.84
266_A	269_K	0.830	0.84
57_G	60_A	0.829	0.84
89_A	92_A	0.829	0.84
316_V	322_L	0.822	0.84
23_L	77_L	0.818	0.83
152_E	156_A	0.817	0.83
184_A	188_A	0.813	0.83
32_I	71_W	0.810	0.83
156_A	159_A	0.809	0.83
2_Q	130_D	0.806	0.83
47_E	96_Y	0.806	0.83
96_Y	122_N	0.799	0.82
42_L	118_A	0.796	0.82
317_C	320_L	0.795	0.82
193_A	196_A	0.794	0.82
282_A	285_I	0.790	0.81
9_F	112_V	0.789	0.81
268_A	271_D	0.787	0.81
4_L	101_P	0.787	0.81
209_K	212_A	0.786	0.81
66_I	69_L	0.784	0.81
11_G	16_P	0.782	0.81
307_A	328_A	0.780	0.80
197_D	201_A	0.780	0.80
214_D	218_F	0.778	0.80
135_L	138_A	0.777	0.80
27_S	32_I	0.775	0.80
4_L	103_F	0.771	0.80
270_K	274_A	0.766	0.79
39_G	128_G	0.766	0.79
268_A	272_L	0.762	0.79
44_I	66_I	0.760	0.79
23_L	31_V	0.759	0.79
258_P	261_K	0.759	0.79
317_C	322_L	0.758	0.79
12_R	40_N	0.758	0.79
46_Y	86_R	0.753	0.78
178_A	182_A	0.752	0.78
167_A	171_E	0.751	0.78
217_K	220_P	0.750	0.78
242_E	272_L	0.750	0.78
126_L	129_L	0.748	0.78
268_A	275_F	0.748	0.78
61_P	90_A	0.746	0.77
263_W	271_D	0.743	0.77
39_G	127_D	0.741	0.77
243_A	265_R	0.739	0.77
31_V	103_F	0.739	0.77
21_W	105_Y	0.739	0.77
25_D	28_A	0.735	0.76
256_I	263_W	0.734	0.76
152_E	155_K	0.733	0.76
155_K	159_A	0.733	0.76
163_L	175_A	0.731	0.76
308_A	328_A	0.731	0.76
263_W	275_F	0.730	0.76
267_L	270_K	0.730	0.76
71_W	75_D	0.728	0.76
11_G	21_W	0.728	0.76
55_P	58_Q	0.727	0.76
35_F	66_I	0.727	0.76
185_A	188_A	0.726	0.76
173_L	177_T	0.722	0.75
86_R	93_A	0.722	0.75
143_T	147_E	0.720	0.75
238_L	242_E	0.719	0.75
84_T	87_A	0.715	0.74
42_L	117_S	0.714	0.74
264_A	268_A	0.714	0.74
215_P	219_V	0.714	0.74
44_I	81_V	0.709	0.74
316_V	327_F	0.708	0.74
198_L	202_A	0.707	0.74
308_A	311_A	0.706	0.73
233_A	237_E	0.705	0.73
83_W	120_L	0.700	0.73
47_E	59_P	0.699	0.73
2_Q	40_N	0.699	0.73
266_A	270_K	0.698	0.73
248_D	251_L	0.697	0.73
177_T	180_K	0.697	0.73
202_A	206_A	0.695	0.72
154_L	172_I	0.694	0.72
285_I	289_G	0.693	0.72
204_A	207_A	0.692	0.72
260_Q	278_F	0.691	0.72
187_A	191_G	0.690	0.72
253_D	284_P	0.687	0.71
21_W	125_A	0.684	0.71
324_P	327_F	0.682	0.71
13_D	16_P	0.682	0.71
191_G	195_D	0.680	0.71
230_E	234_L	0.680	0.71
163_L	172_I	0.676	0.70
158_L	167_A	0.676	0.70
102_V	123_T	0.672	0.70
313_E	320_L	0.670	0.70
267_L	271_D	0.668	0.69
52_L	55_P	0.668	0.69
156_A	177_T	0.667	0.69
255_K	282_A	0.667	0.69
30_A	111_R	0.666	0.69
43_V	102_V	0.663	0.69
52_L	56_N	0.661	0.69
161_L	176_L	0.660	0.68
234_L	238_L	0.655	0.68
314_L	320_L	0.652	0.67
44_I	63_A	0.652	0.67
274_A	278_F	0.651	0.67
160_A	177_T	0.650	0.67
87_A	92_A	0.649	0.67
221_V	224_V	0.649	0.67
307_A	310_S	0.646	0.67
197_D	202_A	0.645	0.67
216_A	219_V	0.643	0.66
38_R	114_R	0.642	0.66
320_L	324_P	0.640	0.66
312_E	315_A	0.639	0.66
42_L	66_I	0.639	0.66
159_A	165_E	0.638	0.66
220_P	224_V	0.637	0.66
267_L	275_F	0.637	0.66
218_F	221_V	0.636	0.66
186_V	191_G	0.636	0.66
2_Q	75_D	0.635	0.65
246_L	250_A	0.633	0.65
29_A	32_I	0.633	0.65
192_L	195_D	0.633	0.65
45_D	50_T	0.631	0.65
275_F	278_F	0.631	0.65
251_L	255_K	0.630	0.65
78_W	129_L	0.624	0.64
4_L	23_L	0.624	0.64
60_A	96_Y	0.623	0.64
190_L	195_D	0.621	0.64
263_W	274_A	0.621	0.64
323_S	328_A	0.617	0.63
67_K	94_K	0.616	0.63
320_L	326_D	0.615	0.63
4_L	115_L	0.612	0.63
169_E	175_A	0.609	0.62
199_A	202_A	0.608	0.62
171_E	174_A	0.606	0.62
50_T	116_L	0.606	0.62
306_A	320_L	0.605	0.62
43_V	61_P	0.604	0.62
133_A	136_A	0.604	0.62
116_L	123_T	0.604	0.62
41_D	132_L	0.602	0.61
243_A	271_D	0.602	0.61
235_K	239_A	0.602	0.61
162_G	178_A	0.601	0.61
251_L	258_P	0.600	0.61
163_L	168_T	0.599	0.61
60_A	87_A	0.598	0.61
255_K	283_P	0.597	0.61
158_L	162_G	0.597	0.61
27_S	111_R	0.597	0.61
104_L	114_R	0.593	0.60
65_W	122_N	0.587	0.59
291_T	294_G	0.585	0.59
6_A	23_L	0.583	0.59
320_L	328_A	0.581	0.59
246_L	275_F	0.581	0.59
192_L	202_A	0.580	0.58
162_G	165_E	0.580	0.58
153_L	158_L	0.580	0.58
286_A	290_G	0.578	0.58
6_A	73_E	0.577	0.58
254_G	286_A	0.575	0.58
174_A	177_T	0.574	0.58
70_E	80_R	0.571	0.57
147_E	151_E	0.570	0.57
79_A	99_I	0.570	0.57
174_A	181_A	0.568	0.57
46_Y	49_Q	0.568	0.57
186_V	192_L	0.568	0.57
94_K	97_R	0.563	0.56
305_G	308_A	0.563	0.56
121_T	124_P	0.562	0.56
118_A	126_L	0.561	0.56
72_R	80_R	0.560	0.56
196_A	200_A	0.557	0.55
32_I	35_F	0.554	0.55
157_L	161_L	0.552	0.55
21_W	103_F	0.552	0.55
188_A	191_G	0.549	0.54
173_L	182_A	0.548	0.54
23_L	32_I	0.548	0.54
263_W	282_A	0.548	0.54
292_Q	295_G	0.547	0.54
260_Q	281_A	0.546	0.54
40_N	43_V	0.544	0.54
192_L	204_A	0.543	0.54
156_A	170_E	0.543	0.54
205_V	208_L	0.543	0.54
254_G	284_P	0.542	0.53
30_A	34_A	0.541	0.53
153_L	169_E	0.540	0.53
186_V	194_A	0.539	0.53
16_P	21_W	0.537	0.53
71_W	78_W	0.535	0.53
307_A	317_C	0.534	0.52
34_A	38_R	0.533	0.52
177_T	319_A	0.533	0.52
22_R	27_S	0.533	0.52
159_A	162_G	0.533	0.52
263_W	266_A	0.532	0.52
77_L	121_T	0.532	0.52
251_L	265_R	0.532	0.52
246_L	272_L	0.531	0.52
319_A	324_P	0.530	0.52
61_P	102_V	0.528	0.52
35_F	69_L	0.528	0.52
175_A	183_A	0.527	0.51
313_E	328_A	0.526	0.51
158_L	169_E	0.526	0.51
47_E	58_Q	0.524	0.51
159_A	175_A	0.522	0.51
217_K	221_V	0.522	0.51
317_C	326_D	0.521	0.51
263_W	270_K	0.519	0.50
90_A	93_A	0.519	0.50
308_A	324_P	0.518	0.50
264_A	274_A	0.517	0.50
188_A	194_A	0.517	0.50
45_D	102_V	0.517	0.50
158_L	164_P	0.516	0.50
190_L	204_A	0.515	0.50
95_E	98_Y	0.513	0.50
306_A	323_S	0.513	0.50
117_S	120_L	0.512	0.49
83_W	101_P	0.512	0.49
42_L	79_A	0.510	0.49
50_T	57_G	0.509	0.49
46_Y	84_T	0.509	0.49
28_A	31_V	0.508	0.49
307_A	311_A	0.507	0.49
129_L	135_L	0.507	0.49
310_S	317_C	0.506	0.49
194_A	201_A	0.506	0.49
28_A	132_L	0.505	0.48
11_G	15_R	0.504	0.48
142_E	146_E	0.504	0.48
158_L	165_E	0.503	0.48
257_T	282_A	0.503	0.48
291_T	295_G	0.502	0.48
32_I	36_A	0.501	0.48
216_A	221_V	0.501	0.48
35_F	77_L	0.501	0.48
157_L	172_I	0.500	0.48
98_Y	124_P	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3aieA	3	0.3982	26.8	0.954	Contact Map
1m2dA	2	0.1185	23.1	0.955	Contact Map
1npbA	3	0.2736	11.2	0.961	Contact Map
2k48A	1	0.3191	8.7	0.963	Contact Map
1ei5A	2	0.3556	8.2	0.963	Contact Map
2aqeA	1	0.1307	8.2	0.963	Contact Map
2ckkA	1	0.1459	7.6	0.964	Contact Map
2eljA	1	0.1246	7.2	0.964	Contact Map
2ou3A	2	0.3556	6.8	0.965	Contact Map
4tvcA	1	0.3435	6.6	0.965	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.01 seconds.