GREMLIN Database
DUF2339 - Predicted membrane protein (DUF2339)
PFAM: PF10101 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 664 (653)
Sequences: 3873 (3474)
Seq/√Len: 135.9
META: 0.785

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
22_K26_D5.4841.00
110_N157_K4.3741.00
10_I67_G4.1881.00
69_I102_A4.0871.00
43_G71_V3.9991.00
31_P34_L3.8861.00
122_G146_L3.8791.00
87_P90_L3.7961.00
50_G65_Q3.5011.00
187_F191_E3.3001.00
40_A76_V3.2231.00
417_L423_E3.1311.00
16_G648_I3.0871.00
258_L283_A2.9821.00
423_E427_L2.9331.00
344_L348_R2.9271.00
628_L632_L2.8951.00
112_Q161_W2.7691.00
48_G52_R2.7411.00
15_L19_F2.6941.00
47_L68_G2.6911.00
3_N7_K2.6041.00
248_L252_A2.5871.00
246_L249_S2.5831.00
558_L562_L2.5581.00
99_T122_G2.5561.00
616_R661_Y2.5011.00
196_L200_L2.4131.00
363_L366_L2.3301.00
288_T307_E2.3271.00
345_L348_R2.3111.00
307_E311_L2.3091.00
558_L563_L2.2991.00
220_D227_N2.2931.00
37_A41_L2.2881.00
571_V575_G2.2811.00
259_A263_L2.2701.00
292_P304_W2.2681.00
195_L199_L2.2441.00
560_L564_L2.2051.00
17_V71_V2.2011.00
1_G4_L2.2001.00
198_F201_F2.1901.00
345_L349_L2.1841.00
295_L299_W2.1711.00
514_N517_D2.1681.00
135_N138_A2.1651.00
604_M619_G2.1611.00
144_A196_L2.1121.00
485_A489_L2.1061.00
95_M125_A2.1001.00
423_E426_Y2.0941.00
366_L369_G2.0561.00
43_G68_G2.0511.00
197_F201_F2.0451.00
46_L67_G2.0141.00
291_I303_A2.0071.00
291_I300_T2.0011.00
344_L349_L1.9961.00
244_Y247_A1.9791.00
202_L256_L1.9601.00
482_L486_L1.9591.00
102_A118_G1.9581.00
391_A395_W1.9561.00
617_I621_A1.9561.00
458_L462_R1.9481.00
616_R620_L1.9411.00
553_A564_L1.9401.00
80_Y91_A1.9031.00
516_L519_A1.8641.00
191_E195_L1.8541.00
489_L494_L1.8321.00
76_V98_V1.8291.00
511_P514_N1.8111.00
80_Y88_P1.7851.00
24_A29_L1.7781.00
490_L495_L1.7741.00
193_F198_F1.7741.00
30_I38_L1.7701.00
343_A348_R1.7681.00
331_L335_A1.7671.00
395_W398_R1.7551.00
571_V576_D1.7401.00
24_A50_G1.7351.00
79_A86_I1.7331.00
246_L250_A1.7331.00
591_G595_L1.7281.00
571_V574_Q1.7061.00
50_G61_A1.7001.00
202_L205_A1.6991.00
369_G372_F1.6931.00
187_F193_F1.6851.00
254_A257_Y1.6831.00
249_S252_A1.6781.00
78_A82_L1.6671.00
553_A562_L1.6631.00
247_A250_A1.6581.00
14_V70_A1.6461.00
227_N231_A1.6451.00
77_F81_R1.6441.00
554_L558_L1.6431.00
43_G72_L1.6431.00
445_W449_P1.6421.00
126_P142_Y1.6411.00
220_D224_L1.6401.00
608_I661_Y1.6381.00
607_G616_R1.6351.00
613_R617_I1.6351.00
193_F201_F1.6341.00
193_F197_F1.6251.00
486_L490_L1.6211.00
343_A346_L1.6151.00
299_W303_A1.6091.00
529_L533_L1.6051.00
187_F192_P1.6031.00
553_A557_A1.6021.00
608_I616_R1.5981.00
198_F205_A1.5901.00
80_Y131_T1.5821.00
552_L556_L1.5811.00
186_H189_S1.5751.00
498_A501_L1.5721.00
69_I105_L1.5701.00
412_A416_L1.5681.00
4_L7_K1.5591.00
174_G178_G1.5561.00
73_Y121_G1.5501.00
150_I166_G1.5501.00
43_G75_T1.5381.00
602_A606_L1.5371.00
244_Y249_S1.5291.00
47_L72_L1.5241.00
21_L39_G1.5091.00
203_A207_L1.4781.00
44_L48_G1.4731.00
17_V21_L1.4681.00
624_G628_L1.4601.00
445_W448_L1.4571.00
557_A564_L1.4561.00
522_L525_L1.4561.00
606_L610_R1.4531.00
417_L420_L1.4501.00
190_T193_F1.4401.00
316_G324_A1.4401.00
393_A397_L1.4391.00
104_A108_R1.4381.00
232_F293_L1.4311.00
89_T93_A1.4301.00
569_L584_V1.4301.00
555_A559_L1.4281.00
6_V63_V1.4251.00
353_W357_A1.4231.00
262_A266_R1.4221.00
20_L29_L1.4171.00
191_E198_F1.3931.00
549_L564_L1.3901.00
340_L343_A1.3871.00
557_A561_F1.3861.00
187_F190_T1.3851.00
424_L427_L1.3831.00
334_L338_S1.3791.00
198_F204_I1.3771.00
62_L111_S1.3771.00
357_A360_P1.3741.00
643_R646_S1.3671.00
619_G626_V1.3661.00
333_L337_L1.3641.00
295_L303_A1.3631.00
486_L489_L1.3621.00
198_F202_L1.3571.00
466_R469_R1.3511.00
205_A208_F1.3491.00
72_L98_V1.3491.00
60_F64_L1.3411.00
475_R479_G1.3401.00
123_F147_N1.3361.00
207_L210_L1.3361.00
123_F146_L1.3301.00
191_E235_Q1.3301.00
490_L494_L1.3221.00
518_L522_L1.3211.00
629_K634_D1.3201.00
483_L487_L1.3181.00
641_L645_I1.3151.00
83_Y126_P1.3131.00
103_V152_A1.3091.00
246_L252_A1.3001.00
498_A502_L1.2951.00
321_R324_A1.2931.00
552_L559_L1.2911.00
525_L529_L1.2901.00
193_F200_L1.2881.00
554_L561_F1.2871.00
190_T198_F1.2871.00
560_L563_L1.2851.00
528_L532_R1.2831.00
465_R469_R1.2801.00
558_L561_F1.2791.00
73_Y99_T1.2781.00
32_P35_R1.2761.00
427_L431_G1.2721.00
188_A192_P1.2711.00
198_F208_F1.2691.00
594_I649_G1.2651.00
54_R108_R1.2641.00
457_A461_L1.2561.00
600_A623_L1.2541.00
246_L253_L1.2531.00
189_S192_P1.2511.00
557_A562_L1.2501.00
600_A654_L1.2471.00
17_V20_L1.2461.00
519_A523_P1.2401.00
33_E37_A1.2331.00
527_L531_A1.2321.00
99_T149_G1.2291.00
261_A280_L1.2271.00
137_V141_S1.2251.00
333_L336_A1.2251.00
212_F215_A1.2241.00
194_L197_F1.2241.00
339_A343_A1.2211.00
659_F663_R1.2141.00
554_L564_L1.2121.00
54_R61_A1.2061.00
392_L396_L1.2061.00
193_F196_L1.2061.00
39_G75_T1.2021.00
459_L463_R1.1981.00
191_E201_F1.1941.00
620_L661_Y1.1941.00
551_A554_L1.1911.00
623_L654_L1.1901.00
224_L227_N1.1891.00
619_G623_L1.1860.99
205_A209_A1.1830.99
36_V85_L1.1820.99
346_L349_L1.1790.99
174_G177_W1.1750.99
206_L209_A1.1720.99
175_L180_L1.1720.99
188_A191_E1.1710.99
643_R647_F1.1690.99
559_L562_L1.1680.99
374_G377_A1.1680.99
481_L490_L1.1670.99
274_L278_A1.1660.99
51_E65_Q1.1650.99
23_Y27_H1.1640.99
121_G126_P1.1630.99
196_L201_F1.1610.99
204_I208_F1.1590.99
332_L336_A1.1570.99
221_G227_N1.1570.99
635_L643_R1.1510.99
361_L366_L1.1500.99
449_P452_L1.1490.99
11_L15_L1.1450.99
197_F202_L1.1420.99
45_A49_A1.1390.99
98_V102_A1.1380.99
190_T197_F1.1380.99
23_Y644_I1.1370.99
239_L242_F1.1350.99
227_N233_G1.1340.99
459_L464_R1.1340.99
245_G248_L1.1310.99
36_V83_Y1.1300.99
438_W441_L1.1280.99
94_L98_V1.1250.99
51_E55_R1.1240.99
336_A343_A1.1220.99
53_L60_F1.1220.99
630_L650_L1.1200.99
607_G620_L1.1200.99
292_P300_T1.1190.99
80_Y95_M1.1160.99
26_D35_R1.1130.99
561_F564_L1.1130.99
328_G331_L1.1110.99
631_F654_L1.1110.99
273_R277_E1.1080.99
373_L376_L1.1070.99
413_L417_L1.1060.99
340_L344_L1.1050.99
496_V500_P1.1020.99
425_R429_D1.1020.99
116_V165_L1.0980.99
175_L179_L1.0970.99
449_P453_F1.0970.99
470_L474_Y1.0970.99
99_T121_G1.0940.99
306_L309_A1.0910.99
317_L325_R1.0910.99
65_Q109_Y1.0880.99
95_M129_L1.0880.99
593_S629_K1.0870.99
154_A163_N1.0870.99
460_L463_R1.0850.99
568_L595_L1.0790.99
123_F169_F1.0770.99
420_L423_E1.0760.99
389_A396_L1.0750.99
220_D228_P1.0730.99
341_L344_L1.0690.99
558_L564_L1.0690.99
136_H140_F1.0680.99
86_I90_L1.0620.99
308_G312_L1.0570.99
352_A357_A1.0570.99
491_L495_L1.0570.99
365_L369_G1.0550.99
343_A347_R1.0500.99
650_L654_L1.0460.99
316_G328_G1.0450.99
387_A391_A1.0420.99
517_D520_Y1.0390.99
428_L431_G1.0380.99
194_L201_F1.0370.99
12_I630_L1.0350.99
362_L366_L1.0310.99
175_L234_L1.0310.99
417_L427_L1.0290.99
278_A281_A1.0270.99
554_L559_L1.0250.99
148_A200_L1.0250.99
362_L365_L1.0190.98
483_L486_L1.0180.98
95_M149_G1.0170.98
572_L575_G1.0170.98
194_L198_F1.0160.98
531_A535_R1.0160.98
604_M608_I1.0140.98
195_L198_F1.0110.98
115_A162_L1.0090.98
17_V42_A1.0070.98
607_G661_Y1.0060.98
197_F200_L1.0060.98
457_A460_L1.0050.98
331_L336_A1.0040.98
448_L452_L1.0030.98
24_A35_R1.0020.98
254_A283_A1.0000.98
462_R466_R1.0000.98
341_L349_L0.9980.98
5_L657_I0.9940.98
66_G125_A0.9930.98
344_L347_R0.9930.98
497_L500_P0.9890.98
600_A657_I0.9880.98
10_I117_L0.9870.98
232_F236_Y0.9870.98
6_V10_I0.9850.98
382_G386_P0.9840.98
324_A328_G0.9780.98
13_L23_Y0.9770.98
152_A156_F0.9760.98
489_L492_L0.9760.98
136_H189_S0.9750.98
638_L650_L0.9750.98
553_A556_L0.9750.98
220_D223_L0.9740.98
362_L369_G0.9690.98
203_A206_L0.9680.98
658_S661_Y0.9670.98
457_A463_R0.9670.98
201_F208_F0.9660.98
304_W307_E0.9660.98
201_F205_A0.9650.98
32_P36_V0.9650.98
25_I39_G0.9620.98
286_F292_P0.9620.98
483_L490_L0.9600.98
36_V39_G0.9580.98
25_I28_G0.9560.98
131_T134_G0.9500.98
40_A72_L0.9480.98
139_L142_Y0.9450.97
226_G235_Q0.9430.97
446_L449_P0.9430.97
482_L489_L0.9420.97
643_R649_G0.9370.97
417_L428_L0.9360.97
341_L345_L0.9350.97
144_A200_L0.9350.97
659_F662_Q0.9320.97
599_L603_L0.9320.97
638_L642_Y0.9310.97
195_L231_A0.9310.97
475_R478_A0.9290.97
76_V94_L0.9280.97
413_L423_E0.9270.97
627_V654_L0.9240.97
553_A561_F0.9240.97
205_A210_L0.9230.97
197_F203_A0.9220.97
616_R662_Q0.9200.97
50_G60_F0.9190.97
245_G249_S0.9180.97
479_G485_A0.9170.97
244_Y248_L0.9170.97
244_Y250_A0.9160.97
383_Y386_P0.9160.97
186_H190_T0.9130.97
202_L206_L0.9130.97
220_D299_W0.9110.97
7_K10_I0.9110.97
219_V225_F0.9100.97
351_L354_S0.9090.97
559_L563_L0.9070.97
616_R663_R0.9060.97
92_F95_M0.9060.97
484_L490_L0.9060.97
474_Y477_G0.9050.97
620_L658_S0.9040.97
462_R465_R0.9020.97
51_E54_R0.9000.97
6_V658_S0.9000.97
359_L362_L0.8980.97
123_F150_I0.8920.96
484_L495_L0.8910.96
409_H412_A0.8880.96
606_L615_L0.8880.96
100_A104_A0.8870.96
393_A412_A0.8860.96
499_N502_L0.8850.96
113_A117_L0.8850.96
5_L600_A0.8850.96
134_G138_A0.8840.96
360_P363_L0.8830.96
520_Y524_L0.8800.96
190_T201_F0.8790.96
419_L423_E0.8780.96
66_G105_L0.8760.96
50_G68_G0.8760.96
621_A625_L0.8760.96
590_A593_S0.8750.96
103_V107_L0.8750.96
76_V91_A0.8720.96
651_G654_L0.8720.96
227_N235_Q0.8710.96
471_A475_R0.8700.96
147_N201_F0.8680.96
247_A252_A0.8650.96
388_A392_L0.8640.96
254_A258_L0.8640.96
652_L656_V0.8630.96
552_L564_L0.8630.96
4_L8_I0.8630.96
83_Y121_G0.8620.96
248_L251_L0.8610.96
598_L602_A0.8610.96
554_L563_L0.8600.96
148_A152_A0.8600.96
232_F286_F0.8600.96
342_L345_L0.8590.96
253_L257_Y0.8590.96
107_L156_F0.8590.96
14_V18_A0.8560.96
427_L432_V0.8530.95
648_I652_L0.8530.95
574_Q577_A0.8530.95
330_P338_S0.8510.95
14_V74_L0.8510.95
2_G7_K0.8510.95
324_A334_L0.8490.95
480_A483_L0.8480.95
135_N139_L0.8470.95
130_S134_G0.8470.95
375_P378_W0.8470.95
250_A253_L0.8460.95
13_L16_G0.8460.95
618_A621_A0.8440.95
247_A253_L0.8430.95
424_L428_L0.8420.95
183_R186_H0.8400.95
364_L369_G0.8400.95
395_W399_R0.8380.95
575_G580_A0.8360.95
635_L638_L0.8340.95
571_V585_Q0.8340.95
655_L659_F0.8330.95
421_A427_L0.8320.95
195_L201_F0.8300.95
325_R328_G0.8280.95
197_F205_A0.8270.95
572_L577_A0.8260.95
471_A474_Y0.8260.95
186_H191_E0.8260.95
321_R328_G0.8250.95
423_E428_L0.8240.94
352_A360_P0.8240.94
335_A338_S0.8220.94
573_W577_A0.8210.94
202_L208_F0.8190.94
231_A235_Q0.8180.94
550_A564_L0.8170.94
36_V79_A0.8170.94
553_A558_L0.8150.94
219_V224_L0.8150.94
18_A22_K0.8130.94
447_A450_A0.8110.94
282_L286_F0.8110.94
32_P83_Y0.8100.94
352_A362_L0.8070.94
420_L424_L0.8060.94
530_W533_L0.8060.94
191_E197_F0.8040.94
36_V40_A0.8020.94
247_A251_L0.8020.94
557_A563_L0.8010.94
460_L465_R0.8010.94
353_W360_P0.8010.94
230_V234_L0.8000.94
492_L495_L0.7970.93
30_I71_V0.7960.93
7_K17_V0.7950.93
325_R329_L0.7940.93
416_L423_E0.7940.93
247_A294_A0.7920.93
487_L491_L0.7910.93
131_T135_N0.7900.93
322_R326_R0.7900.93
7_K113_A0.7900.93
236_Y246_L0.7900.93
518_L521_L0.7880.93
88_P129_L0.7880.93
391_A396_L0.7850.93
220_D235_Q0.7850.93
51_E109_Y0.7850.93
389_A393_A0.7820.93
316_G325_R0.7780.93
254_A287_L0.7770.93
460_L464_R0.7770.93
549_L562_L0.7760.93
597_G626_V0.7760.93
25_I35_R0.7750.92
79_A85_L0.7740.92
601_L605_V0.7730.92
324_A327_F0.7730.92
14_V17_V0.7730.92
144_A148_A0.7720.92
631_F650_L0.7720.92
126_P162_L0.7660.92
596_W599_L0.7660.92
121_G142_Y0.7650.92
187_F194_L0.7650.92
224_L228_P0.7650.92
551_A562_L0.7640.92
228_P232_F0.7630.92
324_A333_L0.7620.92
553_A563_L0.7610.92
30_I39_G0.7590.92
95_M99_T0.7580.92
324_A331_L0.7580.92
553_A559_L0.7570.92
455_A462_R0.7570.92
67_G71_V0.7550.91
227_N230_V0.7530.91
13_L46_L0.7530.91
106_A115_A0.7510.91
189_S193_F0.7500.91
423_E432_V0.7500.91
445_W452_L0.7490.91
277_E280_L0.7480.91
563_L570_R0.7450.91
249_S253_L0.7440.91
627_V643_R0.7440.91
482_L494_L0.7430.91
52_R55_R0.7430.91
224_L232_F0.7420.91
363_L368_L0.7420.91
658_S662_Q0.7420.91
481_L485_A0.7420.91
341_L348_R0.7410.91
417_L424_L0.7400.91
313_W318_R0.7380.91
6_V61_A0.7370.90
456_L460_L0.7350.90
3_N12_I0.7340.90
223_L230_V0.7340.90
62_L125_A0.7340.90
463_R466_R0.7330.90
229_L233_G0.7330.90
470_L473_L0.7320.90
573_W576_D0.7310.90
557_A560_L0.7310.90
621_A624_G0.7300.90
36_V75_T0.7300.90
12_I19_F0.7290.90
529_L532_R0.7290.90
457_A462_R0.7260.90
339_A344_L0.7250.90
10_I60_F0.7240.90
405_R409_H0.7230.90
226_G232_F0.7230.90
572_L576_D0.7220.90
300_T304_W0.7190.89
390_L394_A0.7190.89
486_L493_L0.7170.89
49_A53_L0.7160.89
244_Y252_A0.7160.89
115_A159_W0.7160.89
552_L560_L0.7160.89
83_Y142_Y0.7140.89
635_L640_T0.7130.89
550_A553_A0.7130.89
460_L466_R0.7100.89
458_L461_L0.7100.89
528_L531_A0.7100.89
266_R269_R0.7090.89
21_L78_A0.7090.89
130_S133_S0.7080.89
574_Q579_A0.7070.89
88_P95_M0.7070.89
220_D231_A0.7070.89
472_R476_L0.7050.88
327_F333_L0.7040.88
419_L424_L0.7040.88
6_V109_Y0.7030.88
22_K142_Y0.7030.88
199_L256_L0.7030.88
251_L290_A0.7030.88
200_L204_I0.7030.88
228_P231_A0.7020.88
420_L427_L0.7010.88
235_Q249_S0.7000.88
421_A424_L0.7000.88
222_T227_N0.6990.88
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63_V114_L0.6940.88
223_L228_P0.6930.88
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40_A75_T0.6920.88
516_L523_P0.6910.87
245_G250_A0.6910.87
491_L494_L0.6910.87
26_D29_L0.6900.87
225_F229_L0.6900.87
118_G125_A0.6900.87
126_P139_L0.6900.87
136_H190_T0.6890.87
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193_F204_I0.6880.87
54_R109_Y0.6860.87
605_V624_G0.6860.87
77_F80_Y0.6840.87
326_R333_L0.6840.87
351_L357_A0.6830.87
561_F595_L0.6820.87
363_L369_G0.6820.87
575_G579_A0.6820.87
600_A622_L0.6810.87
330_P333_L0.6810.87
291_I304_W0.6800.87
285_A327_F0.6800.87
412_A431_G0.6790.87
517_D524_L0.6780.86
496_V499_N0.6770.86
519_A529_L0.6760.86
229_L235_Q0.6750.86
63_V117_L0.6730.86
105_L109_Y0.6720.86
340_L345_L0.6710.86
639_G642_Y0.6700.86
414_L424_L0.6700.86
319_Q325_R0.6700.86
172_L179_L0.6690.86
403_R407_V0.6690.86
513_L517_D0.6680.86
9_G655_L0.6680.86
38_L42_A0.6670.86
330_P334_L0.6650.85
193_F202_L0.6640.85
243_E246_L0.6620.85
307_E310_A0.6610.85
479_G492_L0.6610.85
490_L493_L0.6610.85
420_L452_L0.6590.85
422_L425_R0.6590.85
61_A95_M0.6570.85
414_L418_L0.6570.85
19_F647_F0.6560.85
482_L492_L0.6550.85
364_L367_L0.6540.84
487_L493_L0.6540.84
394_A401_E0.6540.84
12_I24_A0.6540.84
537_A540_L0.6520.84
603_L622_L0.6520.84
452_L455_A0.6520.84
393_A396_L0.6510.84
608_I620_L0.6510.84
143_L147_N0.6510.84
283_A290_A0.6480.84
532_R536_R0.6470.84
359_L363_L0.6450.84
28_G35_R0.6440.84
119_L149_G0.6440.84
333_L338_S0.6430.83
223_L226_G0.6430.83
448_L451_L0.6430.83
478_A486_L0.6420.83
63_V67_G0.6420.83
329_L332_L0.6400.83
654_L662_Q0.6390.83
331_L338_S0.6390.83
356_L360_P0.6390.83
387_A393_A0.6390.83
41_L45_A0.6380.83
573_W585_Q0.6370.83
225_F228_P0.6360.83
35_R83_Y0.6350.83
475_R480_A0.6350.83
13_L60_F0.6340.83
203_A210_L0.6340.83
77_F82_L0.6330.82
95_M128_L0.6330.82
88_P149_G0.6330.82
480_A488_L0.6320.82
54_R62_L0.6320.82
524_L528_L0.6320.82
102_A105_L0.6280.82
453_F464_R0.6280.82
351_L362_L0.6280.82
10_I63_V0.6270.82
115_A153_I0.6240.82
221_G225_F0.6230.81
532_R535_R0.6220.81
334_L337_L0.6210.81
604_M627_V0.6200.81
21_L25_I0.6200.81
593_S634_D0.6190.81
563_L566_A0.6190.81
225_F232_F0.6160.81
550_A554_L0.6150.81
455_A458_L0.6140.81
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343_A349_L0.6130.80
352_A355_A0.6120.80
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337_L341_L0.6110.80
117_L146_L0.6090.80
593_S599_L0.6090.80
203_A209_A0.6090.80
272_L275_L0.6090.80
357_A361_L0.6080.80
410_A414_L0.6080.80
191_E194_L0.6070.80
342_L348_R0.6070.80
147_N150_I0.6060.80
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74_L129_L0.6050.80
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488_L494_L0.6030.79
20_L24_A0.6010.79
191_E200_L0.6010.79
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55_R58_R0.5980.79
193_F208_F0.5970.79
112_Q116_V0.5970.79
318_R321_R0.5960.79
34_L38_L0.5950.78
73_Y122_G0.5950.78
65_Q69_I0.5950.78
571_V578_L0.5950.78
58_R110_N0.5940.78
227_N239_L0.5940.78
87_P636_S0.5930.78
575_G578_L0.5930.78
39_G43_G0.5930.78
63_V113_A0.5920.78
99_T129_L0.5910.78
199_L203_A0.5910.78
591_G594_I0.5900.78
482_L493_L0.5870.78
381_L385_L0.5870.78
553_A560_L0.5860.77
409_H417_L0.5860.77
571_V581_S0.5860.77
6_V60_F0.5850.77
396_L399_R0.5850.77
382_G385_L0.5830.77
50_G109_Y0.5830.77
557_A599_L0.5820.77
321_R325_R0.5820.77
192_P201_F0.5810.77
362_L368_L0.5810.77
411_A417_L0.5800.77
593_S630_L0.5800.77
257_Y260_L0.5800.77
571_V577_A0.5800.77
319_Q322_R0.5790.77
33_E85_L0.5780.76
484_L488_L0.5750.76
136_H169_F0.5750.76
630_L642_Y0.5740.76
485_A488_L0.5740.76
519_A524_L0.5730.76
288_T291_I0.5720.76
219_V226_G0.5720.76
73_Y98_V0.5720.76
361_L367_L0.5720.76
22_K25_I0.5710.76
519_A532_R0.5710.76
479_G483_L0.5710.76
276_A281_A0.5700.75
551_A564_L0.5700.75
68_G643_R0.5690.75
359_L366_L0.5690.75
51_E60_F0.5690.75
127_F173_I0.5690.75
73_Y113_A0.5680.75
219_V223_L0.5670.75
325_R332_L0.5660.75
489_L493_L0.5650.75
349_L353_W0.5650.75
225_F231_A0.5640.75
96_V99_T0.5640.75
9_G654_L0.5630.75
359_L365_L0.5620.74
125_A159_W0.5620.74
350_A360_P0.5610.74
365_L368_L0.5600.74
477_G480_A0.5600.74
627_V631_F0.5600.74
330_P336_A0.5600.74
171_F234_L0.5590.74
191_E207_L0.5590.74
9_G16_G0.5580.74
92_F139_L0.5580.74
487_L496_V0.5580.74
453_F457_A0.5570.74
453_F462_R0.5570.74
197_F208_F0.5570.74
367_L371_G0.5570.74
235_Q239_L0.5560.74
296_D300_T0.5560.74
325_R333_L0.5550.74
187_F197_F0.5550.74
273_R276_A0.5550.74
398_R401_E0.5550.74
253_L256_L0.5540.73
506_A509_G0.5540.73
327_F334_L0.5540.73
556_L563_L0.5540.73
574_Q578_L0.5540.73
608_I619_G0.5540.73
482_L488_L0.5540.73
622_L629_K0.5520.73
428_L432_V0.5520.73
411_A419_L0.5510.73
60_F113_A0.5500.73
487_L490_L0.5500.73
597_G600_A0.5500.73
92_F130_S0.5490.73
623_L657_I0.5490.73
147_N170_T0.5490.73
337_L343_A0.5480.73
16_G32_P0.5480.73
484_L491_L0.5480.73
604_M616_R0.5480.73
274_L277_E0.5470.72
397_L401_E0.5470.72
304_W308_G0.5470.72
199_L202_L0.5460.72
190_T200_L0.5460.72
551_A558_L0.5460.72
66_G74_L0.5450.72
80_Y92_F0.5450.72
76_V95_M0.5450.72
342_L346_L0.5440.72
329_L333_L0.5440.72
59_A63_V0.5420.72
417_L421_A0.5420.72
538_R542_A0.5410.72
83_Y91_A0.5410.72
61_A111_S0.5400.71
412_A423_E0.5390.71
44_L72_L0.5390.71
411_A426_Y0.5380.71
387_A412_A0.5380.71
122_G142_Y0.5370.71
52_R56_K0.5370.71
487_L492_L0.5370.71
176_L179_L0.5370.71
122_G149_G0.5350.71
125_A143_L0.5350.71
387_A394_A0.5350.71
412_A417_L0.5350.71
342_L349_L0.5350.71
29_L39_G0.5350.71
526_L529_L0.5340.71
631_F636_S0.5340.71
4_L61_A0.5340.71
18_A21_L0.5330.71
461_L466_R0.5320.70
554_L562_L0.5310.70
511_P518_L0.5300.70
484_L487_L0.5300.70
517_D531_A0.5300.70
228_P235_Q0.5290.70
334_L343_A0.5290.70
320_R326_R0.5280.70
223_L227_N0.5280.70
590_A599_L0.5270.70
25_I30_I0.5270.70
22_K92_F0.5270.70
297_G300_T0.5260.70
318_R327_F0.5260.70
512_L516_L0.5260.70
497_L502_L0.5250.69
163_N167_F0.5250.69
6_V20_L0.5250.69
187_F198_F0.5250.69
319_Q323_L0.5250.69
20_L42_A0.5250.69
110_N173_I0.5240.69
611_R618_A0.5240.69
513_L516_L0.5230.69
512_L515_P0.5230.69
34_L37_A0.5220.69
633_V655_L0.5220.69
360_P364_L0.5210.69
60_F63_V0.5210.69
20_L38_L0.5210.69
471_A477_G0.5210.69
341_L346_L0.5200.69
245_G252_A0.5200.69
421_A426_Y0.5190.69
102_A125_A0.5180.68
454_L460_L0.5180.68
489_L495_L0.5170.68
540_L543_G0.5170.68
647_F657_I0.5170.68
265_R268_K0.5160.68
273_R281_A0.5160.68
9_G73_Y0.5150.68
561_F567_V0.5150.68
130_S135_N0.5150.68
60_F73_Y0.5150.68
405_R408_L0.5140.68
308_G328_G0.5140.68
340_L348_R0.5130.68
629_K651_G0.5130.68
42_A46_L0.5120.67
324_A335_A0.5120.67
538_R541_A0.5110.67
392_L395_W0.5110.67
576_D580_A0.5110.67
412_A427_L0.5110.67
452_L456_L0.5100.67
191_E209_A0.5090.67
60_F67_G0.5090.67
17_V70_A0.5090.67
41_L44_L0.5080.67
374_G378_W0.5080.67
130_S139_L0.5070.67
260_L264_L0.5060.67
431_G434_F0.5050.66
182_Y187_F0.5050.66
323_L327_F0.5050.66
192_P198_F0.5040.66
488_L492_L0.5030.66
521_L532_R0.5020.66
334_L347_R0.5010.66
10_I28_G0.5010.66
57_Y149_G0.5000.66
106_A129_L0.5000.66
325_R334_L0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ksfA 1 0.1611 12.7 0.971 Contact Map
3o7qA 1 0.1581 3.3 0.978 Contact Map
4b19A 1 0.0452 3.2 0.978 Contact Map
4m5bA 1 0.1265 3.1 0.978 Contact Map
3j1rA 5 0.0392 2.7 0.979 Contact Map
3j01B 1 0.0813 1.9 0.98 Contact Map
2kixA 3 0.0497 1.9 0.98 Contact Map
2mmuA 1 0.0753 1.7 0.981 Contact Map
4cbfA 7 0.1054 1.5 0.982 Contact Map
1scfA 4 0 1.2 0.982 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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