GREMLIN Database
DUF2309 - Uncharacterized protein conserved in bacteria (DUF2309)
PFAM: PF10070 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 752 (746)
Sequences: 2419 (1889)
Seq/√Len: 69.2
META: 0.682

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
286_R526_D8.7101.00
448_A515_G8.0561.00
466_P556_D7.7171.00
452_E519_R7.0331.00
449_D519_R6.3211.00
517_A522_D5.7261.00
471_V532_A5.3811.00
452_E456_R4.6281.00
451_A507_A4.5871.00
649_E739_R4.0761.00
476_S535_D3.8661.00
447_Q509_D3.8161.00
656_M724_V3.8051.00
466_P553_H3.7051.00
125_F219_V3.5751.00
652_L726_I3.5061.00
614_A632_A3.4141.00
292_V470_L3.3971.00
291_A469_L3.2121.00
549_L557_L3.0191.00
105_C216_L3.0121.00
622_L727_E2.9851.00
20_H24_H2.9771.00
475_S537_T2.9681.00
168_R229_E2.9611.00
166_L180_L2.9271.00
29_L37_R2.9231.00
546_L561_R2.9131.00
3_H177_E2.9081.00
667_Y671_V2.8781.00
744_R748_D2.8101.00
735_A739_R2.7961.00
314_E636_S2.7901.00
616_I623_T2.7781.00
48_L52_E2.7641.00
66_D268_R2.7631.00
469_L532_A2.7491.00
326_I502_V2.7151.00
528_W553_H2.6441.00
468_V529_F2.6281.00
444_L448_A2.6241.00
486_L708_S2.6201.00
297_V486_L2.5891.00
451_A506_M2.5501.00
290_Q465_A2.5021.00
57_L64_D2.4921.00
316_F458_M2.4671.00
445_E515_G2.4361.00
320_G496_G2.4311.00
48_L53_Y2.4311.00
266_Y613_A2.4271.00
645_G732_A2.4261.00
653_T740_H2.4201.00
670_T715_E2.4131.00
451_A503_L2.4081.00
660_Q664_L2.4051.00
469_L564_L2.4031.00
528_W550_P2.4011.00
57_L258_W2.3951.00
461_T464_F2.3891.00
443_T446_E2.3891.00
706_W709_V2.3661.00
162_I218_A2.3521.00
292_V458_M2.3261.00
55_E59_S2.2781.00
111_Q197_R2.2721.00
339_L499_N2.2651.00
532_A543_L2.2581.00
550_P553_H2.2551.00
302_F541_V2.2541.00
157_D160_D2.2281.00
289_A560_L2.2171.00
301_S571_A2.1991.00
649_E653_T2.1761.00
464_F521_I2.1631.00
540_E594_E2.1561.00
503_L507_A2.1411.00
162_I221_L2.1411.00
514_A518_E2.1051.00
19_A24_H2.0991.00
318_F454_A2.0851.00
20_H665_Q2.0531.00
619_P727_E2.0501.00
511_E514_A2.0481.00
466_P552_S2.0391.00
310_G563_D2.0141.00
195_R199_W2.0131.00
310_G313_I1.9861.00
466_P526_D1.9811.00
158_P215_D1.9781.00
618_G622_L1.9731.00
528_W549_L1.9571.00
470_L503_L1.9501.00
32_E47_Y1.9501.00
288_A310_G1.9491.00
291_A471_V1.9431.00
454_A458_M1.9391.00
289_A313_I1.9371.00
467_L560_L1.9141.00
288_A559_R1.8981.00
474_G495_P1.8901.00
56_A61_R1.8541.00
314_E463_N1.8531.00
693_M698_G1.8511.00
474_G533_L1.8231.00
599_D602_E1.8201.00
309_V570_L1.8031.00
543_L557_L1.8011.00
482_H705_P1.7901.00
70_A257_I1.7801.00
19_A665_Q1.7571.00
461_T641_Q1.7551.00
110_D113_Q1.7471.00
683_P694_E1.7431.00
288_A312_G1.7301.00
30_P33_E1.7251.00
32_E260_E1.7101.00
539_D575_R1.6981.00
325_P450_R1.6740.99
147_F151_V1.6660.99
553_H556_D1.6650.99
673_N709_V1.6650.99
330_P333_D1.6630.99
483_A486_L1.6620.99
308_E570_L1.6560.99
457_A650_L1.6540.99
125_F211_I1.6390.99
454_A503_L1.6220.99
50_R254_R1.6160.99
61_R718_E1.6140.99
741_P744_R1.6130.99
613_A631_R1.6100.99
319_A655_P1.6010.99
166_L176_W1.5830.99
270_L614_A1.5830.99
617_V659_A1.5810.99
538_T597_A1.5790.99
173_E176_W1.5650.99
734_E738_A1.5490.99
324_V506_M1.5450.99
694_E701_R1.5430.99
501_R545_D1.5410.99
515_G518_E1.5380.99
595_R602_E1.5340.99
50_R255_R1.5280.99
162_I214_V1.5250.99
560_L564_L1.5190.99
665_Q708_S1.5170.99
329_Q349_L1.5090.99
687_V693_M1.5080.99
651_I654_A1.5080.99
566_E570_L1.5070.99
10_P19_A1.5070.99
118_M121_R1.5050.99
327_Y338_P1.5020.99
649_E736_I1.5020.99
554_R558_A1.5000.99
56_A262_Y1.4990.99
556_D559_R1.4920.99
292_V318_F1.4710.99
743_V747_V1.4630.99
737_L742_A1.4510.99
468_V527_T1.4410.98
475_S487_D1.4320.98
165_A225_R1.4320.98
290_Q314_E1.4220.98
431_L434_D1.4180.98
469_L560_L1.4090.98
649_E740_H1.4080.98
309_V563_D1.4010.98
306_L313_I1.4000.98
154_L222_A1.4000.98
52_E55_E1.3980.98
126_Y161_A1.3960.98
724_V752_L1.3950.98
482_H678_S1.3910.98
635_H651_I1.3890.98
273_A629_D1.3810.98
297_V608_G1.3810.98
514_A517_A1.3800.98
130_R156_D1.3800.98
543_L564_L1.3800.98
98_H186_A1.3720.98
497_G533_L1.3690.98
164_E225_R1.3680.98
63_T66_D1.3590.98
433_L502_V1.3540.98
64_D68_E1.3500.98
211_I215_D1.3400.98
578_R716_I1.3390.98
313_I563_D1.3380.98
291_A306_L1.3370.97
736_I740_H1.3340.97
27_E745_E1.3330.97
486_L680_S1.3330.97
449_D452_E1.3310.97
81_L85_L1.3310.97
102_I698_G1.3190.97
302_F568_G1.3160.97
615_F635_H1.3150.97
110_D114_A1.3140.97
481_P485_A1.3120.97
326_I499_N1.3090.97
306_L541_V1.3070.97
301_S574_E1.3020.97
24_H665_Q1.2920.97
329_Q336_P1.2880.97
19_A22_P1.2780.97
320_G323_G1.2770.97
33_E37_R1.2770.97
66_D265_S1.2730.97
639_W729_P1.2720.97
71_L75_L1.2700.97
10_P20_H1.2690.97
150_R229_E1.2630.96
461_T521_I1.2590.96
290_Q316_F1.2580.96
471_V541_V1.2530.96
48_L56_A1.2490.96
76_P88_L1.2490.96
464_F523_I1.2440.96
309_V566_E1.2440.96
656_M659_A1.2410.96
495_P533_L1.2380.96
729_P732_A1.2360.96
546_L549_L1.2260.96
566_E569_A1.2240.96
67_L258_W1.2230.96
620_R623_T1.2160.96
225_R229_E1.2140.96
293_F302_F1.2130.96
481_P686_V1.2120.96
291_A313_I1.2120.96
19_A666_Y1.2110.95
559_R563_D1.2100.95
108_Y118_M1.2100.95
262_Y720_L1.2000.95
52_E56_A1.1960.95
267_Q723_L1.1940.95
343_L654_A1.1930.95
86_D92_D1.1880.95
551_A554_R1.1780.95
20_H666_Y1.1770.95
259_Q667_Y1.1750.95
6_H24_H1.1700.95
638_D641_Q1.1680.95
35_V46_G1.1650.94
76_P85_L1.1610.94
524_P527_T1.1590.94
29_L33_E1.1570.94
637_Y641_Q1.1570.94
467_L528_W1.1550.94
558_A561_R1.1520.94
464_F524_P1.1490.94
456_R461_T1.1470.94
574_E627_D1.1420.94
612_N663_N1.1350.94
655_P724_V1.1330.94
639_W645_G1.1310.93
486_L607_W1.1300.93
592_H602_E1.1270.93
611_G716_I1.1270.93
262_Y718_E1.1270.93
168_R225_R1.1260.93
305_H574_E1.1250.93
477_S487_D1.1240.93
741_P745_E1.1230.93
608_G706_W1.1220.93
270_L725_V1.1200.93
183_L224_E1.1190.93
266_Y720_L1.1190.93
11_Q17_F1.1160.93
147_F150_R1.1140.93
459_G643_P1.1110.93
726_I733_I1.1100.93
290_Q460_L1.1090.93
444_L515_G1.1090.93
477_S665_Q1.1080.93
582_A592_H1.1050.93
615_F659_A1.1000.93
348_H446_E1.0950.92
77_R81_L1.0940.92
460_L463_N1.0940.92
458_M464_F1.0930.92
631_R718_E1.0890.92
197_R690_I1.0860.92
652_L656_M1.0830.92
738_A741_P1.0820.92
67_L261_A1.0790.92
23_L668_F1.0790.92
728_A732_A1.0770.92
266_Y614_A1.0690.91
492_G623_T1.0680.91
30_P750_G1.0680.91
256_R260_E1.0670.91
289_A563_D1.0660.91
193_M197_R1.0650.91
292_V316_F1.0630.91
535_D538_T1.0610.91
38_A42_F1.0610.91
297_V609_L1.0550.91
86_D91_I1.0540.91
339_L497_G1.0530.91
324_V503_L1.0520.91
287_P463_N1.0520.91
568_G572_A1.0520.91
383_S386_S1.0520.91
429_T432_T1.0490.91
522_D525_D1.0460.91
323_G496_G1.0400.90
453_G457_A1.0380.90
444_L509_D1.0360.90
617_V655_P1.0360.90
12_W22_P1.0330.90
123_K131_E1.0290.90
24_H660_Q1.0270.90
328_Y352_E1.0230.90
486_L608_G1.0210.89
10_P22_P1.0190.89
652_L655_P1.0180.89
172_P175_A1.0180.89
693_M697_G1.0160.89
144_L147_F1.0120.89
287_P314_E1.0080.89
462_K641_Q1.0060.89
635_H655_P1.0060.89
448_A512_V1.0050.89
388_F392_E1.0030.89
499_N512_V0.9940.88
119_P128_A0.9920.88
337_T494_R0.9890.88
463_N521_I0.9880.88
537_T597_A0.9870.88
82_R86_D0.9870.88
172_P176_W0.9870.88
561_R565_E0.9800.87
656_M747_V0.9760.87
656_M743_V0.9750.87
179_Y224_E0.9700.87
101_L223_L0.9680.87
3_H6_H0.9670.87
55_E58_A0.9670.87
731_E735_A0.9620.86
66_D70_A0.9610.86
24_H27_E0.9560.86
269_Q273_A0.9550.86
576_A593_V0.9550.86
295_I659_A0.9540.86
579_L593_V0.9540.86
475_S608_G0.9530.86
286_R466_P0.9530.86
655_P661_W0.9520.86
6_H22_P0.9520.86
126_Y129_W0.9510.86
44_A676_Y0.9510.86
429_T433_L0.9490.86
240_L243_A0.9480.86
325_P442_F0.9480.86
523_I529_F0.9460.85
487_D535_D0.9460.85
608_G705_P0.9410.85
106_A687_V0.9390.85
10_P24_H0.9380.85
504_A531_A0.9370.85
411_R414_R0.9370.85
445_E449_D0.9370.85
146_G151_V0.9330.85
277_H625_G0.9320.85
271_L725_V0.9320.85
38_A44_A0.9320.85
81_L84_L0.9300.85
435_R440_E0.9290.84
467_L553_H0.9280.84
436_L440_E0.9280.84
26_F34_A0.9270.84
651_I655_P0.9270.84
102_I693_M0.9260.84
576_A589_A0.9240.84
684_H694_E0.9220.84
161_A165_A0.9210.84
318_F458_M0.9190.84
304_R574_E0.9180.84
82_R85_L0.9160.84
609_L708_S0.9160.84
39_A45_R0.9140.83
23_L38_A0.9140.83
710_H715_E0.9110.83
594_E597_A0.9100.83
565_E568_G0.9100.83
736_I739_R0.9090.83
6_H20_H0.9090.83
44_A675_R0.9070.83
321_F496_G0.9070.83
652_L736_I0.9070.83
63_T518_E0.9050.83
432_T435_R0.8990.82
555_A559_R0.8990.82
53_Y259_Q0.8990.82
179_Y183_L0.8990.82
19_A708_S0.8980.82
647_V650_L0.8980.82
326_I350_V0.8960.82
23_L27_E0.8950.82
14_L484_S0.8950.82
93_W224_E0.8940.82
342_V492_G0.8940.82
8_I11_Q0.8880.82
552_S556_D0.8880.82
495_P607_W0.8860.82
549_L553_H0.8850.81
299_S534_H0.8850.81
478_V608_G0.8840.81
711_D716_I0.8840.81
328_Y350_V0.8820.81
266_Y631_R0.8820.81
18_V342_V0.8800.81
80_T83_D0.8800.81
647_V656_M0.8800.81
110_D116_W0.8770.81
105_C125_F0.8750.81
291_A560_L0.8740.81
558_A562_A0.8740.81
708_S715_E0.8730.81
680_S683_P0.8700.80
486_L670_T0.8690.80
445_E448_A0.8650.80
706_W715_E0.8640.80
160_D164_E0.8630.80
659_A740_H0.8600.80
327_Y336_P0.8590.79
193_M690_I0.8580.79
735_A738_A0.8580.79
15_K111_Q0.8570.79
20_H25_G0.8570.79
52_E262_Y0.8560.79
530_V543_L0.8560.79
429_T435_R0.8540.79
405_R478_V0.8530.79
518_E521_I0.8510.79
98_H187_L0.8500.79
45_R255_R0.8480.79
112_G119_P0.8480.79
161_A225_R0.8430.78
535_D596_R0.8420.78
152_A251_E0.8420.78
133_A139_P0.8420.78
486_L603_V0.8410.78
8_I16_D0.8400.78
736_I743_V0.8380.78
510_P525_D0.8360.78
731_E734_E0.8360.78
387_G391_V0.8350.78
339_L494_R0.8340.77
583_P602_E0.8330.77
348_H442_F0.8330.77
737_L752_L0.8310.77
327_Y349_L0.8300.77
224_E260_E0.8300.77
445_E519_R0.8280.77
126_Y155_P0.8260.77
600_W655_P0.8250.77
62_I258_W0.8250.77
477_S486_L0.8250.77
596_R602_E0.8240.77
324_V454_A0.8230.77
383_S387_G0.8230.77
617_V656_M0.8220.76
120_G123_K0.8200.76
514_A525_D0.8190.76
99_P103_R0.8190.76
273_A626_L0.8180.76
61_R269_Q0.8170.76
215_D690_I0.8170.76
600_W657_V0.8160.76
148_R151_V0.8160.76
222_A226_A0.8140.76
532_A541_V0.8130.76
324_V502_V0.8120.76
58_A163_A0.8100.75
22_P25_G0.8090.75
301_S578_R0.8070.75
442_F506_M0.8050.75
295_I496_G0.8040.75
81_L88_L0.8010.75
326_I450_R0.7980.74
728_A733_I0.7980.74
273_A627_D0.7980.74
429_T434_D0.7960.74
487_D705_P0.7960.74
569_A590_L0.7930.74
126_Y154_L0.7930.74
297_V680_S0.7930.74
730_P734_E0.7930.74
323_G454_A0.7930.74
465_A739_R0.7930.74
543_L546_L0.7910.74
16_D484_S0.7910.74
301_S630_G0.7900.74
61_R262_Y0.7900.74
18_V24_H0.7890.73
535_D542_T0.7880.73
188_P192_G0.7870.73
186_A220_R0.7870.73
11_Q482_H0.7860.73
653_T743_V0.7860.73
51_A518_E0.7850.73
100_Q138_T0.7850.73
62_I262_Y0.7830.73
9_P20_H0.7820.73
12_W16_D0.7820.73
297_V630_G0.7780.72
340_C346_P0.7770.72
310_G559_R0.7760.72
474_G487_D0.7740.72
85_L91_I0.7730.72
738_A744_R0.7730.72
121_R128_A0.7730.72
338_P494_R0.7730.72
592_H595_R0.7720.72
609_L661_W0.7720.72
47_Y259_Q0.7720.72
537_T593_V0.7720.72
581_S589_A0.7710.72
486_L661_W0.7700.72
126_Y145_P0.7700.72
39_A252_L0.7690.72
118_M132_L0.7690.72
5_A213_L0.7690.72
27_E660_Q0.7690.72
196_W200_Q0.7690.72
45_R672_D0.7690.72
47_Y256_R0.7650.71
125_F194_I0.7620.71
710_H713_D0.7600.71
576_A581_S0.7590.71
665_Q668_F0.7590.71
53_Y62_I0.7590.71
483_A607_W0.7590.71
164_E167_E0.7590.71
305_H570_L0.7580.70
143_G147_F0.7580.70
32_E256_R0.7570.70
266_Y270_L0.7540.70
576_A580_P0.7530.70
725_V747_V0.7510.70
97_V224_E0.7510.70
22_P708_S0.7510.70
7_V26_F0.7500.70
259_Q682_L0.7500.70
733_I736_I0.7490.70
482_H692_V0.7480.69
102_I187_L0.7480.69
526_D556_D0.7480.69
650_L653_T0.7470.69
468_V523_I0.7470.69
161_A222_A0.7470.69
127_A215_D0.7470.69
551_A555_A0.7450.69
617_V651_I0.7450.69
23_L672_D0.7430.69
404_A412_S0.7400.69
526_D550_P0.7390.68
113_Q686_V0.7390.68
318_F343_L0.7380.68
22_P665_Q0.7370.68
659_A724_V0.7370.68
455_L460_L0.7360.68
48_L54_R0.7350.68
198_E213_L0.7350.68
599_D610_A0.7340.68
323_G391_V0.7330.68
737_L748_D0.7330.68
609_L635_H0.7320.68
63_T265_S0.7310.68
619_P640_R0.7310.68
684_H701_R0.7310.68
600_W607_W0.7300.68
543_L560_L0.7290.67
35_V38_A0.7290.67
607_W630_G0.7290.67
270_L632_A0.7290.67
322_F496_G0.7280.67
129_W133_A0.7280.67
620_R628_L0.7280.67
259_Q720_L0.7260.67
4_A35_V0.7250.67
100_Q103_R0.7240.67
253_E256_R0.7240.67
157_D162_I0.7240.67
184_L217_L0.7230.67
265_S718_E0.7230.67
609_L655_P0.7230.67
572_A589_A0.7200.66
124_G215_D0.7190.66
186_A602_E0.7190.66
33_E591_R0.7190.66
262_Y324_V0.7190.66
734_E737_L0.7190.66
47_Y667_Y0.7190.66
19_A25_G0.7180.66
328_Y339_L0.7180.66
167_E280_A0.7180.66
737_L744_R0.7160.66
646_S649_E0.7150.66
436_L439_E0.7150.66
737_L743_V0.7140.66
76_P81_L0.7140.66
222_A225_R0.7130.66
255_R259_Q0.7130.66
316_F414_R0.7130.66
68_E731_E0.7130.66
10_P665_Q0.7120.66
23_L42_F0.7110.65
62_I265_S0.7110.65
185_L675_R0.7110.65
288_A563_D0.7100.65
11_Q24_H0.7100.65
100_Q223_L0.7090.65
653_T736_I0.7090.65
363_R366_R0.7080.65
743_V748_D0.7080.65
203_A210_P0.7080.65
184_L191_A0.7060.65
426_P429_T0.7060.65
20_H708_S0.7060.65
360_A363_R0.7050.65
266_Y632_A0.7050.65
37_R40_R0.7050.65
470_L531_A0.7040.65
76_P80_T0.7040.65
377_W380_F0.7030.65
495_P544_F0.7020.64
69_A264_R0.7000.64
723_L752_L0.7000.64
444_L511_E0.6980.64
92_D95_E0.6970.64
316_F636_S0.6960.64
461_T643_P0.6950.64
274_L725_V0.6950.64
161_A164_E0.6940.64
487_D608_G0.6940.64
694_E697_G0.6930.63
316_F464_F0.6920.63
140_E146_G0.6920.63
44_A672_D0.6920.63
358_A428_R0.6900.63
28_D745_E0.6890.63
4_A181_H0.6880.63
643_P646_S0.6880.63
302_F537_T0.6870.63
390_F398_Y0.6870.63
155_P161_A0.6860.63
471_V543_L0.6850.63
674_E701_R0.6840.62
459_G647_V0.6840.62
53_Y671_V0.6830.62
53_Y502_V0.6830.62
742_A745_E0.6820.62
392_E486_L0.6820.62
600_W609_L0.6820.62
366_R370_R0.6810.62
17_F31_F0.6810.62
425_P429_T0.6810.62
257_I752_L0.6800.62
348_H450_R0.6790.62
57_L62_I0.6790.62
105_C612_N0.6780.62
285_A551_A0.6780.62
443_T447_Q0.6770.62
736_I746_L0.6760.62
615_F630_G0.6750.61
732_A735_A0.6740.61
452_E652_L0.6740.61
660_Q746_L0.6740.61
85_L88_L0.6720.61
350_V502_V0.6710.61
474_G498_P0.6700.61
121_R124_G0.6700.61
535_D678_S0.6680.61
316_F460_L0.6670.61
458_M470_L0.6670.61
397_L400_L0.6670.61
467_L530_V0.6650.60
487_D495_P0.6650.60
158_P162_I0.6650.60
562_A566_E0.6640.60
654_A747_V0.6630.60
537_T610_A0.6620.60
325_P344_L0.6610.60
487_D597_A0.6610.60
82_R92_D0.6600.60
336_P349_L0.6590.60
297_V603_V0.6590.60
565_E569_A0.6580.60
742_A748_D0.6580.60
680_S706_W0.6570.59
51_A58_A0.6570.59
431_L435_R0.6560.59
51_A55_E0.6560.59
28_D174_E0.6540.59
318_F457_A0.6540.59
323_G503_L0.6520.59
609_L615_F0.6510.59
144_L150_R0.6500.59
478_V495_P0.6500.59
503_L506_M0.6490.58
375_R378_H0.6480.58
555_A558_A0.6480.58
360_A364_R0.6470.58
270_L628_L0.6470.58
46_G676_Y0.6450.58
150_R225_R0.6450.58
468_V552_S0.6450.58
590_L594_E0.6440.58
609_L630_G0.6430.58
650_L740_H0.6430.58
173_E517_A0.6420.58
85_L89_T0.6410.58
31_F256_R0.6400.57
652_L743_V0.6400.57
367_R420_G0.6390.57
103_R612_N0.6390.57
297_V708_S0.6380.57
38_A668_F0.6380.57
426_P431_L0.6380.57
340_C503_L0.6370.57
619_P638_D0.6360.57
633_F637_Y0.6360.57
32_E36_A0.6360.57
56_A59_S0.6350.57
88_L92_D0.6340.57
297_V607_W0.6340.57
528_W548_L0.6330.57
646_S650_L0.6320.56
98_H101_L0.6320.56
162_I467_L0.6310.56
535_D597_A0.6310.56
318_F635_H0.6300.56
325_P564_L0.6300.56
562_A726_I0.6300.56
611_G630_G0.6290.56
293_F391_V0.6290.56
343_L653_T0.6290.56
55_E358_A0.6280.56
332_G363_R0.6280.56
535_D540_E0.6280.56
672_D675_R0.6280.56
415_L419_L0.6270.56
173_E525_D0.6270.56
340_C636_S0.6260.56
33_E518_E0.6260.56
633_F663_N0.6260.56
325_P340_C0.6260.56
154_L165_A0.6260.56
462_K525_D0.6250.56
577_R627_D0.6250.56
35_V47_Y0.6240.55
410_R413_A0.6230.55
652_L724_V0.6230.55
77_R82_R0.6210.55
143_G146_G0.6200.55
80_T87_A0.6190.55
609_L627_D0.6190.55
661_W665_Q0.6180.55
299_S609_L0.6170.55
4_A16_D0.6150.54
687_V736_I0.6150.54
124_G127_A0.6140.54
109_L212_T0.6140.54
578_R629_D0.6140.54
565_E738_A0.6140.54
693_M716_I0.6130.54
102_I106_A0.6130.54
362_R447_Q0.6120.54
129_W136_D0.6120.54
435_R438_D0.6120.54
574_E579_L0.6110.54
477_S483_A0.6110.54
33_E51_A0.6100.54
108_Y125_F0.6100.54
657_V661_W0.6090.54
160_D163_A0.6080.54
656_M740_H0.6080.54
561_R727_E0.6070.53
77_R80_T0.6060.53
471_V530_V0.6050.53
545_D548_L0.6050.53
5_A199_W0.6040.53
99_P693_M0.6040.53
670_T708_S0.6040.53
340_C602_E0.6040.53
579_L596_R0.6040.53
343_L470_L0.6040.53
462_K522_D0.6030.53
448_A738_A0.6020.53
323_G534_H0.6020.53
104_W219_V0.6020.53
107_A114_A0.6020.53
352_E699_D0.6020.53
223_L701_R0.6010.53
652_L752_L0.6000.53
297_V661_W0.6000.53
330_P741_P0.6000.53
111_Q603_V0.6000.53
129_W599_D0.5990.53
262_Y265_S0.5990.53
478_V537_T0.5990.53
108_Y179_Y0.5970.52
570_L573_A0.5970.52
413_A598_V0.5960.52
63_T69_A0.5960.52
295_I607_W0.5960.52
650_L654_A0.5950.52
215_D226_A0.5940.52
338_P346_P0.5940.52
318_F650_L0.5940.52
475_S500_A0.5940.52
8_I184_L0.5930.52
54_R58_A0.5930.52
462_K554_R0.5930.52
208_A731_E0.5930.52
673_N706_W0.5930.52
580_P607_W0.5930.52
616_I634_L0.5920.52
396_L400_L0.5920.52
14_L20_H0.5920.52
52_E670_T0.5920.52
88_L91_I0.5920.52
94_D98_H0.5910.52
305_H308_E0.5910.52
97_V626_L0.5910.52
193_M196_W0.5910.52
635_H659_A0.5910.52
608_G665_Q0.5900.51
165_A169_L0.5860.51
610_A695_G0.5860.51
683_P701_R0.5850.51
487_D533_L0.5850.51
523_I629_D0.5850.51
11_Q16_D0.5850.51
308_E578_R0.5850.51
683_P689_L0.5850.51
265_S686_V0.5840.51
422_M425_P0.5830.51
167_E173_E0.5830.51
713_D736_I0.5830.51
571_A608_G0.5820.50
393_A396_L0.5820.50
169_L179_Y0.5820.50
297_V538_T0.5820.50
199_W202_D0.5810.50
356_D445_E0.5790.50
394_L398_Y0.5790.50
49_P52_E0.5790.50
37_R42_F0.5780.50
568_G594_E0.5780.50
617_V726_I0.5780.50
615_F724_V0.5770.50
33_E55_E0.5770.50
62_I67_L0.5770.50
350_V442_F0.5770.50
617_V634_L0.5770.50
95_E470_L0.5760.50
648_L733_I0.5760.50
472_G531_A0.5760.50
660_Q665_Q0.5750.50
259_Q262_Y0.5750.50
26_F31_F0.5750.50
683_P712_G0.5750.50
38_A46_G0.5740.49
23_L47_Y0.5740.49
711_D714_R0.5740.49
486_L495_P0.5730.49
295_I320_G0.5730.49
293_F651_I0.5720.49
281_P552_S0.5720.49
331_L354_P0.5710.49
476_S597_A0.5710.49
109_L113_Q0.5710.49
607_W716_I0.5700.49
6_H11_Q0.5700.49
328_Y374_E0.5700.49
382_R387_G0.5700.49
621_S643_P0.5700.49
421_H431_L0.5690.49
85_L92_D0.5690.49
501_R574_E0.5690.49
733_I742_A0.5690.49
275_A738_A0.5680.49
312_G563_D0.5680.49
18_V297_V0.5670.49
433_L505_A0.5670.49
650_L736_I0.5670.49
392_E600_W0.5660.49
393_A403_L0.5660.49
5_A158_P0.5650.48
98_H102_I0.5650.48
515_G519_R0.5640.48
660_Q694_E0.5640.48
511_E709_V0.5640.48
321_F655_P0.5640.48
452_E516_L0.5640.48
730_P733_I0.5620.48
80_T84_L0.5620.48
700_L707_Q0.5620.48
223_L482_H0.5610.48
46_G49_P0.5610.48
300_E304_R0.5610.48
43_G47_Y0.5600.48
517_A525_D0.5600.48
339_L495_P0.5590.48
501_R547_D0.5590.48
532_A564_L0.5590.48
510_P521_I0.5590.48
571_A630_G0.5590.48
94_D186_A0.5580.48
9_P12_W0.5570.47
109_L211_I0.5570.47
362_R366_R0.5570.47
9_P24_H0.5570.47
503_L603_V0.5560.47
11_Q23_L0.5560.47
581_S602_E0.5560.47
573_A590_L0.5560.47
687_V698_G0.5550.47
454_A470_L0.5550.47
174_E241_A0.5540.47
456_R650_L0.5540.47
61_R265_S0.5530.47
355_A548_L0.5530.47
38_A109_L0.5520.47
78_L84_L0.5520.47
682_L706_W0.5520.47
663_N734_E0.5520.47
129_W161_A0.5520.47
487_D665_Q0.5520.47
626_L672_D0.5510.47
748_D752_L0.5510.47
415_L420_G0.5510.47
398_Y696_N0.5500.47
84_L91_I0.5500.47
130_R222_A0.5490.46
288_A311_P0.5490.46
56_A266_Y0.5490.46
249_F254_R0.5490.46
511_E515_G0.5480.46
29_L34_A0.5480.46
481_P664_L0.5480.46
272_A511_E0.5480.46
724_V743_V0.5480.46
617_V650_L0.5470.46
610_A709_V0.5470.46
89_T231_A0.5470.46
740_H743_V0.5470.46
109_L194_I0.5460.46
632_A692_V0.5460.46
34_A38_A0.5450.46
6_H665_Q0.5450.46
295_I617_V0.5440.46
611_G715_E0.5440.46
8_I302_F0.5430.46
654_A659_A0.5430.46
97_V100_Q0.5430.46
568_G590_L0.5430.46
26_F37_R0.5420.46
478_V483_A0.5420.46
146_G150_R0.5420.46
365_R525_D0.5420.46
460_L464_F0.5420.46
427_P431_L0.5410.46
96_L139_P0.5410.46
329_Q351_K0.5400.45
11_Q20_H0.5390.45
148_R153_A0.5390.45
14_L185_L0.5380.45
497_G544_F0.5380.45
109_L193_M0.5380.45
126_Y130_R0.5380.45
653_T742_A0.5380.45
63_T514_A0.5370.45
452_E464_F0.5370.45
609_L660_Q0.5370.45
317_G633_F0.5370.45
432_T514_A0.5370.45
180_L183_L0.5360.45
319_A472_G0.5360.45
68_E468_V0.5360.45
377_W651_I0.5350.45
323_G696_N0.5350.45
486_L610_A0.5350.45
297_V492_G0.5350.45
414_R510_P0.5350.45
299_S661_W0.5350.45
694_E746_L0.5340.45
656_M752_L0.5340.45
327_Y494_R0.5340.45
104_W128_A0.5340.45
611_G629_D0.5330.45
194_I216_L0.5330.45
603_V607_W0.5320.44
215_D624_R0.5320.44
194_I340_C0.5310.44
483_A487_D0.5310.44
286_R591_R0.5310.44
274_L622_L0.5310.44
426_P433_L0.5310.44
366_R423_F0.5310.44
133_A136_D0.5300.44
692_V705_P0.5300.44
299_S655_P0.5290.44
625_G709_V0.5290.44
164_E168_R0.5290.44
434_D447_Q0.5280.44
703_G707_Q0.5280.44
484_S663_N0.5270.44
306_L532_A0.5250.44
160_D218_A0.5250.44
627_D630_G0.5250.44
78_L88_L0.5250.44
646_S735_A0.5250.44
222_A393_A0.5240.43
588_A652_L0.5240.43
404_A410_R0.5240.43
717_H721_R0.5240.43
103_R132_L0.5240.43
321_F651_I0.5240.43
126_Y158_P0.5230.43
57_L276_A0.5230.43
136_D155_P0.5230.43
458_M461_T0.5220.43
129_W386_S0.5220.43
167_E735_A0.5220.43
541_V567_A0.5220.43
29_L32_E0.5210.43
48_L486_L0.5210.43
615_F657_V0.5210.43
478_V698_G0.5200.43
342_V597_A0.5200.43
653_T720_L0.5200.43
295_I635_H0.5200.43
49_P55_E0.5200.43
442_F450_R0.5190.43
166_L171_I0.5190.43
562_A644_D0.5190.43
172_P214_V0.5190.43
728_A746_L0.5190.43
182_R185_L0.5180.43
482_H694_E0.5180.43
274_L616_I0.5180.43
523_I735_A0.5180.43
338_P345_T0.5180.43
263_E613_A0.5180.43
737_L747_V0.5180.43
661_W708_S0.5180.43
381_K405_R0.5170.43
33_E514_A0.5170.43
607_W715_E0.5170.43
391_V398_Y0.5170.43
128_A350_V0.5160.43
449_D597_A0.5160.43
280_A555_A0.5160.43
258_W535_D0.5160.43
664_L667_Y0.5150.42
439_E522_D0.5150.42
325_P343_L0.5150.42
259_Q576_A0.5150.42
376_A380_F0.5150.42
66_D718_E0.5140.42
297_V483_A0.5140.42
285_A312_G0.5140.42
33_E292_V0.5140.42
533_L607_W0.5130.42
589_A592_H0.5130.42
576_A579_L0.5120.42
706_W710_H0.5120.42
392_E655_P0.5120.42
707_Q717_H0.5120.42
383_S503_L0.5120.42
293_F471_V0.5110.42
363_R426_P0.5110.42
137_L530_V0.5110.42
13_P193_M0.5110.42
689_L701_R0.5110.42
319_A635_H0.5110.42
413_A416_R0.5100.42
401_K405_R0.5100.42
539_D571_A0.5090.42
703_G717_H0.5090.42
4_A184_L0.5090.42
165_A222_A0.5090.42
292_V454_A0.5090.42
347_K446_E0.5090.42
633_F662_I0.5080.42
447_Q451_A0.5080.42
326_I348_H0.5080.42
507_A665_Q0.5070.41
178_D182_R0.5070.41
323_G655_P0.5070.41
11_Q702_T0.5070.41
450_R615_F0.5070.41
476_S495_P0.5070.41
285_A566_E0.5060.41
10_P25_G0.5060.41
105_C194_I0.5060.41
31_F667_Y0.5050.41
152_A532_A0.5050.41
448_A451_A0.5040.41
69_A731_E0.5040.41
195_R213_L0.5030.41
609_L665_Q0.5030.41
385_V389_L0.5020.41
16_D19_A0.5020.41
321_F326_I0.5010.41
729_P733_I0.5010.41
138_T652_L0.5010.41
737_L745_E0.5010.41
654_A657_V0.5010.41
25_G34_A0.5010.41
439_E554_R0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2w3qA 2 0.242 40.4 0.987 Contact Map
2xwsA 2 0.1569 36.9 0.988 Contact Map
3e3iA 6 0.2314 27.4 0.988 Contact Map
3lyhA 2 0.1516 27 0.988 Contact Map
3fauA 3 0.1037 21.6 0.989 Contact Map
2ab1A 1 0.137 21.1 0.989 Contact Map
2ct6A 1 0.117 20.6 0.989 Contact Map
3qd7X 1 0.1529 17.1 0.989 Contact Map
1ym3A 2 0.2008 16.7 0.99 Contact Map
3ipzA 3 0.137 15.9 0.99 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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