DUF2309 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DUF2309 - Uncharacterized protein conserved in bacteria (DUF2309)

PFAM:	PF10070	Sequences: IEHAAHVIPPQWPLKDFVAHNPLHGFEDLPFEEAVARAARLFGARGYLPRAEYREALASGRITDADLEAALEAELPRLPTLRDLLDALTGIDWDELVHPQLIRWCAAYLDQGQAAWPMPGREKGFYAAWRELARHDLTPELMGLPGFRARVAALPDDPEDAIAEALERLGIPEEAWEDYLHRLLLALPGWAGMIRWREWQPDAELQGARPITLVDLLAVRLALERALLEQAAREAWAAALAHAAELEAFEELERRRIWQEAYERSYQRQLLAALAAHAPAPAAAARPAAQAVFCIDVRSESFRRHLEEVGPGIETFGFAGFFGVPIYYQPLGDDHPTPLCPVLLTPKHLVKEVPADGAAAERRRRRRRLRRRAERAWHRFKRSAVSGFLFVEALGLLYALKLLARTLAPRRSARLRDALGHMFAPPPRTRLTLDRLSDEEGFTLEEQADRAEGALRAMGLTKNFAPLVLLVGHGSSSVNNPHASALDCGACGGRPGGPNARVLAAMANDPEVRAGLAERGIDIPDDTWFVAALHDTTTDEVTLFDLDLLPASHRADLARLRADLEEAGALAAAERARRLPSAPLDLAAALRHVERRAVDWAEVRPEWGLAGNAAFIVGPRSLTRGLDLDGRAFLHSYDWRQDPDGSVLELILTAPMVVAQWINLQYYFSTVDNERYGSGSKLPHNVVGLIGVMEGNGGDLRTGLPWQSVHDGDREIHEPLRLLVVIEAPPEAIEAILARHPAVRELVDNGWL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	752 (746)
Sequences:	2419 (1889)
Seq/√Len:	69.2
META:	0.682

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
286_R	526_D	8.710	1.00
448_A	515_G	8.056	1.00
466_P	556_D	7.717	1.00
452_E	519_R	7.033	1.00
449_D	519_R	6.321	1.00
517_A	522_D	5.726	1.00
471_V	532_A	5.381	1.00
452_E	456_R	4.628	1.00
451_A	507_A	4.587	1.00
649_E	739_R	4.076	1.00
476_S	535_D	3.866	1.00
447_Q	509_D	3.816	1.00
656_M	724_V	3.805	1.00
466_P	553_H	3.705	1.00
125_F	219_V	3.575	1.00
652_L	726_I	3.506	1.00
614_A	632_A	3.414	1.00
292_V	470_L	3.397	1.00
291_A	469_L	3.212	1.00
549_L	557_L	3.019	1.00
105_C	216_L	3.012	1.00
622_L	727_E	2.985	1.00
20_H	24_H	2.977	1.00
475_S	537_T	2.968	1.00
168_R	229_E	2.961	1.00
166_L	180_L	2.927	1.00
29_L	37_R	2.923	1.00
546_L	561_R	2.913	1.00
3_H	177_E	2.908	1.00
667_Y	671_V	2.878	1.00
744_R	748_D	2.810	1.00
735_A	739_R	2.796	1.00
314_E	636_S	2.790	1.00
616_I	623_T	2.778	1.00
48_L	52_E	2.764	1.00
66_D	268_R	2.763	1.00
469_L	532_A	2.749	1.00
326_I	502_V	2.715	1.00
528_W	553_H	2.644	1.00
468_V	529_F	2.628	1.00
444_L	448_A	2.624	1.00
486_L	708_S	2.620	1.00
297_V	486_L	2.589	1.00
451_A	506_M	2.550	1.00
290_Q	465_A	2.502	1.00
57_L	64_D	2.492	1.00
316_F	458_M	2.467	1.00
445_E	515_G	2.436	1.00
320_G	496_G	2.431	1.00
48_L	53_Y	2.431	1.00
266_Y	613_A	2.427	1.00
645_G	732_A	2.426	1.00
653_T	740_H	2.420	1.00
670_T	715_E	2.413	1.00
451_A	503_L	2.408	1.00
660_Q	664_L	2.405	1.00
469_L	564_L	2.403	1.00
528_W	550_P	2.401	1.00
57_L	258_W	2.395	1.00
461_T	464_F	2.389	1.00
443_T	446_E	2.389	1.00
706_W	709_V	2.366	1.00
162_I	218_A	2.352	1.00
292_V	458_M	2.326	1.00
55_E	59_S	2.278	1.00
111_Q	197_R	2.272	1.00
339_L	499_N	2.265	1.00
532_A	543_L	2.258	1.00
550_P	553_H	2.255	1.00
302_F	541_V	2.254	1.00
157_D	160_D	2.228	1.00
289_A	560_L	2.217	1.00
301_S	571_A	2.199	1.00
649_E	653_T	2.176	1.00
464_F	521_I	2.163	1.00
540_E	594_E	2.156	1.00
503_L	507_A	2.141	1.00
162_I	221_L	2.141	1.00
514_A	518_E	2.105	1.00
19_A	24_H	2.099	1.00
318_F	454_A	2.085	1.00
20_H	665_Q	2.053	1.00
619_P	727_E	2.050	1.00
511_E	514_A	2.048	1.00
466_P	552_S	2.039	1.00
310_G	563_D	2.014	1.00
195_R	199_W	2.013	1.00
310_G	313_I	1.986	1.00
466_P	526_D	1.981	1.00
158_P	215_D	1.978	1.00
618_G	622_L	1.973	1.00
528_W	549_L	1.957	1.00
470_L	503_L	1.950	1.00
32_E	47_Y	1.950	1.00
288_A	310_G	1.949	1.00
291_A	471_V	1.943	1.00
454_A	458_M	1.939	1.00
289_A	313_I	1.937	1.00
467_L	560_L	1.914	1.00
288_A	559_R	1.898	1.00
474_G	495_P	1.890	1.00
56_A	61_R	1.854	1.00
314_E	463_N	1.853	1.00
693_M	698_G	1.851	1.00
474_G	533_L	1.823	1.00
599_D	602_E	1.820	1.00
309_V	570_L	1.803	1.00
543_L	557_L	1.801	1.00
482_H	705_P	1.790	1.00
70_A	257_I	1.780	1.00
19_A	665_Q	1.757	1.00
461_T	641_Q	1.755	1.00
110_D	113_Q	1.747	1.00
683_P	694_E	1.743	1.00
288_A	312_G	1.730	1.00
30_P	33_E	1.725	1.00
32_E	260_E	1.710	1.00
539_D	575_R	1.698	1.00
325_P	450_R	1.674	0.99
147_F	151_V	1.666	0.99
553_H	556_D	1.665	0.99
673_N	709_V	1.665	0.99
330_P	333_D	1.663	0.99
483_A	486_L	1.662	0.99
308_E	570_L	1.656	0.99
457_A	650_L	1.654	0.99
125_F	211_I	1.639	0.99
454_A	503_L	1.622	0.99
50_R	254_R	1.616	0.99
61_R	718_E	1.614	0.99
741_P	744_R	1.613	0.99
613_A	631_R	1.610	0.99
319_A	655_P	1.601	0.99
166_L	176_W	1.583	0.99
270_L	614_A	1.583	0.99
617_V	659_A	1.581	0.99
538_T	597_A	1.579	0.99
173_E	176_W	1.565	0.99
734_E	738_A	1.549	0.99
324_V	506_M	1.545	0.99
694_E	701_R	1.543	0.99
501_R	545_D	1.541	0.99
515_G	518_E	1.538	0.99
595_R	602_E	1.534	0.99
50_R	255_R	1.528	0.99
162_I	214_V	1.525	0.99
560_L	564_L	1.519	0.99
665_Q	708_S	1.517	0.99
329_Q	349_L	1.509	0.99
687_V	693_M	1.508	0.99
651_I	654_A	1.508	0.99
566_E	570_L	1.507	0.99
10_P	19_A	1.507	0.99
118_M	121_R	1.505	0.99
327_Y	338_P	1.502	0.99
649_E	736_I	1.502	0.99
554_R	558_A	1.500	0.99
56_A	262_Y	1.499	0.99
556_D	559_R	1.492	0.99
292_V	318_F	1.471	0.99
743_V	747_V	1.463	0.99
737_L	742_A	1.451	0.99
468_V	527_T	1.441	0.98
475_S	487_D	1.432	0.98
165_A	225_R	1.432	0.98
290_Q	314_E	1.422	0.98
431_L	434_D	1.418	0.98
469_L	560_L	1.409	0.98
649_E	740_H	1.408	0.98
309_V	563_D	1.401	0.98
306_L	313_I	1.400	0.98
154_L	222_A	1.400	0.98
52_E	55_E	1.398	0.98
126_Y	161_A	1.396	0.98
724_V	752_L	1.395	0.98
482_H	678_S	1.391	0.98
635_H	651_I	1.389	0.98
273_A	629_D	1.381	0.98
297_V	608_G	1.381	0.98
514_A	517_A	1.380	0.98
130_R	156_D	1.380	0.98
543_L	564_L	1.380	0.98
98_H	186_A	1.372	0.98
497_G	533_L	1.369	0.98
164_E	225_R	1.368	0.98
63_T	66_D	1.359	0.98
433_L	502_V	1.354	0.98
64_D	68_E	1.350	0.98
211_I	215_D	1.340	0.98
578_R	716_I	1.339	0.98
313_I	563_D	1.338	0.98
291_A	306_L	1.337	0.97
736_I	740_H	1.334	0.97
27_E	745_E	1.333	0.97
486_L	680_S	1.333	0.97
449_D	452_E	1.331	0.97
81_L	85_L	1.331	0.97
102_I	698_G	1.319	0.97
302_F	568_G	1.316	0.97
615_F	635_H	1.315	0.97
110_D	114_A	1.314	0.97
481_P	485_A	1.312	0.97
326_I	499_N	1.309	0.97
306_L	541_V	1.307	0.97
301_S	574_E	1.302	0.97
24_H	665_Q	1.292	0.97
329_Q	336_P	1.288	0.97
19_A	22_P	1.278	0.97
320_G	323_G	1.277	0.97
33_E	37_R	1.277	0.97
66_D	265_S	1.273	0.97
639_W	729_P	1.272	0.97
71_L	75_L	1.270	0.97
10_P	20_H	1.269	0.97
150_R	229_E	1.263	0.96
461_T	521_I	1.259	0.96
290_Q	316_F	1.258	0.96
471_V	541_V	1.253	0.96
48_L	56_A	1.249	0.96
76_P	88_L	1.249	0.96
464_F	523_I	1.244	0.96
309_V	566_E	1.244	0.96
656_M	659_A	1.241	0.96
495_P	533_L	1.238	0.96
729_P	732_A	1.236	0.96
546_L	549_L	1.226	0.96
566_E	569_A	1.224	0.96
67_L	258_W	1.223	0.96
620_R	623_T	1.216	0.96
225_R	229_E	1.214	0.96
293_F	302_F	1.213	0.96
481_P	686_V	1.212	0.96
291_A	313_I	1.212	0.96
19_A	666_Y	1.211	0.95
559_R	563_D	1.210	0.95
108_Y	118_M	1.210	0.95
262_Y	720_L	1.200	0.95
52_E	56_A	1.196	0.95
267_Q	723_L	1.194	0.95
343_L	654_A	1.193	0.95
86_D	92_D	1.188	0.95
551_A	554_R	1.178	0.95
20_H	666_Y	1.177	0.95
259_Q	667_Y	1.175	0.95
6_H	24_H	1.170	0.95
638_D	641_Q	1.168	0.95
35_V	46_G	1.165	0.94
76_P	85_L	1.161	0.94
524_P	527_T	1.159	0.94
29_L	33_E	1.157	0.94
637_Y	641_Q	1.157	0.94
467_L	528_W	1.155	0.94
558_A	561_R	1.152	0.94
464_F	524_P	1.149	0.94
456_R	461_T	1.147	0.94
574_E	627_D	1.142	0.94
612_N	663_N	1.135	0.94
655_P	724_V	1.133	0.94
639_W	645_G	1.131	0.93
486_L	607_W	1.130	0.93
592_H	602_E	1.127	0.93
611_G	716_I	1.127	0.93
262_Y	718_E	1.127	0.93
168_R	225_R	1.126	0.93
305_H	574_E	1.125	0.93
477_S	487_D	1.124	0.93
741_P	745_E	1.123	0.93
608_G	706_W	1.122	0.93
270_L	725_V	1.120	0.93
183_L	224_E	1.119	0.93
266_Y	720_L	1.119	0.93
11_Q	17_F	1.116	0.93
147_F	150_R	1.114	0.93
459_G	643_P	1.111	0.93
726_I	733_I	1.110	0.93
290_Q	460_L	1.109	0.93
444_L	515_G	1.109	0.93
477_S	665_Q	1.108	0.93
582_A	592_H	1.105	0.93
615_F	659_A	1.100	0.93
348_H	446_E	1.095	0.92
77_R	81_L	1.094	0.92
460_L	463_N	1.094	0.92
458_M	464_F	1.093	0.92
631_R	718_E	1.089	0.92
197_R	690_I	1.086	0.92
652_L	656_M	1.083	0.92
738_A	741_P	1.082	0.92
67_L	261_A	1.079	0.92
23_L	668_F	1.079	0.92
728_A	732_A	1.077	0.92
266_Y	614_A	1.069	0.91
492_G	623_T	1.068	0.91
30_P	750_G	1.068	0.91
256_R	260_E	1.067	0.91
289_A	563_D	1.066	0.91
193_M	197_R	1.065	0.91
292_V	316_F	1.063	0.91
535_D	538_T	1.061	0.91
38_A	42_F	1.061	0.91
297_V	609_L	1.055	0.91
86_D	91_I	1.054	0.91
339_L	497_G	1.053	0.91
324_V	503_L	1.052	0.91
287_P	463_N	1.052	0.91
568_G	572_A	1.052	0.91
383_S	386_S	1.052	0.91
429_T	432_T	1.049	0.91
522_D	525_D	1.046	0.91
323_G	496_G	1.040	0.90
453_G	457_A	1.038	0.90
444_L	509_D	1.036	0.90
617_V	655_P	1.036	0.90
12_W	22_P	1.033	0.90
123_K	131_E	1.029	0.90
24_H	660_Q	1.027	0.90
328_Y	352_E	1.023	0.90
486_L	608_G	1.021	0.89
10_P	22_P	1.019	0.89
652_L	655_P	1.018	0.89
172_P	175_A	1.018	0.89
693_M	697_G	1.016	0.89
144_L	147_F	1.012	0.89
287_P	314_E	1.008	0.89
462_K	641_Q	1.006	0.89
635_H	655_P	1.006	0.89
448_A	512_V	1.005	0.89
388_F	392_E	1.003	0.89
499_N	512_V	0.994	0.88
119_P	128_A	0.992	0.88
337_T	494_R	0.989	0.88
463_N	521_I	0.988	0.88
537_T	597_A	0.987	0.88
82_R	86_D	0.987	0.88
172_P	176_W	0.987	0.88
561_R	565_E	0.980	0.87
656_M	747_V	0.976	0.87
656_M	743_V	0.975	0.87
179_Y	224_E	0.970	0.87
101_L	223_L	0.968	0.87
3_H	6_H	0.967	0.87
55_E	58_A	0.967	0.87
731_E	735_A	0.962	0.86
66_D	70_A	0.961	0.86
24_H	27_E	0.956	0.86
269_Q	273_A	0.955	0.86
576_A	593_V	0.955	0.86
295_I	659_A	0.954	0.86
579_L	593_V	0.954	0.86
475_S	608_G	0.953	0.86
286_R	466_P	0.953	0.86
655_P	661_W	0.952	0.86
6_H	22_P	0.952	0.86
126_Y	129_W	0.951	0.86
44_A	676_Y	0.951	0.86
429_T	433_L	0.949	0.86
240_L	243_A	0.948	0.86
325_P	442_F	0.948	0.86
523_I	529_F	0.946	0.85
487_D	535_D	0.946	0.85
608_G	705_P	0.941	0.85
106_A	687_V	0.939	0.85
10_P	24_H	0.938	0.85
504_A	531_A	0.937	0.85
411_R	414_R	0.937	0.85
445_E	449_D	0.937	0.85
146_G	151_V	0.933	0.85
277_H	625_G	0.932	0.85
271_L	725_V	0.932	0.85
38_A	44_A	0.932	0.85
81_L	84_L	0.930	0.85
435_R	440_E	0.929	0.84
467_L	553_H	0.928	0.84
436_L	440_E	0.928	0.84
26_F	34_A	0.927	0.84
651_I	655_P	0.927	0.84
102_I	693_M	0.926	0.84
576_A	589_A	0.924	0.84
684_H	694_E	0.922	0.84
161_A	165_A	0.921	0.84
318_F	458_M	0.919	0.84
304_R	574_E	0.918	0.84
82_R	85_L	0.916	0.84
609_L	708_S	0.916	0.84
39_A	45_R	0.914	0.83
23_L	38_A	0.914	0.83
710_H	715_E	0.911	0.83
594_E	597_A	0.910	0.83
565_E	568_G	0.910	0.83
736_I	739_R	0.909	0.83
6_H	20_H	0.909	0.83
44_A	675_R	0.907	0.83
321_F	496_G	0.907	0.83
652_L	736_I	0.907	0.83
63_T	518_E	0.905	0.83
432_T	435_R	0.899	0.82
555_A	559_R	0.899	0.82
53_Y	259_Q	0.899	0.82
179_Y	183_L	0.899	0.82
19_A	708_S	0.898	0.82
647_V	650_L	0.898	0.82
326_I	350_V	0.896	0.82
23_L	27_E	0.895	0.82
14_L	484_S	0.895	0.82
93_W	224_E	0.894	0.82
342_V	492_G	0.894	0.82
8_I	11_Q	0.888	0.82
552_S	556_D	0.888	0.82
495_P	607_W	0.886	0.82
549_L	553_H	0.885	0.81
299_S	534_H	0.885	0.81
478_V	608_G	0.884	0.81
711_D	716_I	0.884	0.81
328_Y	350_V	0.882	0.81
266_Y	631_R	0.882	0.81
18_V	342_V	0.880	0.81
80_T	83_D	0.880	0.81
647_V	656_M	0.880	0.81
110_D	116_W	0.877	0.81
105_C	125_F	0.875	0.81
291_A	560_L	0.874	0.81
558_A	562_A	0.874	0.81
708_S	715_E	0.873	0.81
680_S	683_P	0.870	0.80
486_L	670_T	0.869	0.80
445_E	448_A	0.865	0.80
706_W	715_E	0.864	0.80
160_D	164_E	0.863	0.80
659_A	740_H	0.860	0.80
327_Y	336_P	0.859	0.79
193_M	690_I	0.858	0.79
735_A	738_A	0.858	0.79
15_K	111_Q	0.857	0.79
20_H	25_G	0.857	0.79
52_E	262_Y	0.856	0.79
530_V	543_L	0.856	0.79
429_T	435_R	0.854	0.79
405_R	478_V	0.853	0.79
518_E	521_I	0.851	0.79
98_H	187_L	0.850	0.79
45_R	255_R	0.848	0.79
112_G	119_P	0.848	0.79
161_A	225_R	0.843	0.78
535_D	596_R	0.842	0.78
152_A	251_E	0.842	0.78
133_A	139_P	0.842	0.78
486_L	603_V	0.841	0.78
8_I	16_D	0.840	0.78
736_I	743_V	0.838	0.78
510_P	525_D	0.836	0.78
731_E	734_E	0.836	0.78
387_G	391_V	0.835	0.78
339_L	494_R	0.834	0.77
583_P	602_E	0.833	0.77
348_H	442_F	0.833	0.77
737_L	752_L	0.831	0.77
327_Y	349_L	0.830	0.77
224_E	260_E	0.830	0.77
445_E	519_R	0.828	0.77
126_Y	155_P	0.826	0.77
600_W	655_P	0.825	0.77
62_I	258_W	0.825	0.77
477_S	486_L	0.825	0.77
596_R	602_E	0.824	0.77
324_V	454_A	0.823	0.77
383_S	387_G	0.823	0.77
617_V	656_M	0.822	0.76
120_G	123_K	0.820	0.76
514_A	525_D	0.819	0.76
99_P	103_R	0.819	0.76
273_A	626_L	0.818	0.76
61_R	269_Q	0.817	0.76
215_D	690_I	0.817	0.76
600_W	657_V	0.816	0.76
148_R	151_V	0.816	0.76
222_A	226_A	0.814	0.76
532_A	541_V	0.813	0.76
324_V	502_V	0.812	0.76
58_A	163_A	0.810	0.75
22_P	25_G	0.809	0.75
301_S	578_R	0.807	0.75
442_F	506_M	0.805	0.75
295_I	496_G	0.804	0.75
81_L	88_L	0.801	0.75
326_I	450_R	0.798	0.74
728_A	733_I	0.798	0.74
273_A	627_D	0.798	0.74
429_T	434_D	0.796	0.74
487_D	705_P	0.796	0.74
569_A	590_L	0.793	0.74
126_Y	154_L	0.793	0.74
297_V	680_S	0.793	0.74
730_P	734_E	0.793	0.74
323_G	454_A	0.793	0.74
465_A	739_R	0.793	0.74
543_L	546_L	0.791	0.74
16_D	484_S	0.791	0.74
301_S	630_G	0.790	0.74
61_R	262_Y	0.790	0.74
18_V	24_H	0.789	0.73
535_D	542_T	0.788	0.73
188_P	192_G	0.787	0.73
186_A	220_R	0.787	0.73
11_Q	482_H	0.786	0.73
653_T	743_V	0.786	0.73
51_A	518_E	0.785	0.73
100_Q	138_T	0.785	0.73
62_I	262_Y	0.783	0.73
9_P	20_H	0.782	0.73
12_W	16_D	0.782	0.73
297_V	630_G	0.778	0.72
340_C	346_P	0.777	0.72
310_G	559_R	0.776	0.72
474_G	487_D	0.774	0.72
85_L	91_I	0.773	0.72
738_A	744_R	0.773	0.72
121_R	128_A	0.773	0.72
338_P	494_R	0.773	0.72
592_H	595_R	0.772	0.72
609_L	661_W	0.772	0.72
47_Y	259_Q	0.772	0.72
537_T	593_V	0.772	0.72
581_S	589_A	0.771	0.72
486_L	661_W	0.770	0.72
126_Y	145_P	0.770	0.72
39_A	252_L	0.769	0.72
118_M	132_L	0.769	0.72
5_A	213_L	0.769	0.72
27_E	660_Q	0.769	0.72
196_W	200_Q	0.769	0.72
45_R	672_D	0.769	0.72
47_Y	256_R	0.765	0.71
125_F	194_I	0.762	0.71
710_H	713_D	0.760	0.71
576_A	581_S	0.759	0.71
665_Q	668_F	0.759	0.71
53_Y	62_I	0.759	0.71
483_A	607_W	0.759	0.71
164_E	167_E	0.759	0.71
305_H	570_L	0.758	0.70
143_G	147_F	0.758	0.70
32_E	256_R	0.757	0.70
266_Y	270_L	0.754	0.70
576_A	580_P	0.753	0.70
725_V	747_V	0.751	0.70
97_V	224_E	0.751	0.70
22_P	708_S	0.751	0.70
7_V	26_F	0.750	0.70
259_Q	682_L	0.750	0.70
733_I	736_I	0.749	0.70
482_H	692_V	0.748	0.69
102_I	187_L	0.748	0.69
526_D	556_D	0.748	0.69
650_L	653_T	0.747	0.69
468_V	523_I	0.747	0.69
161_A	222_A	0.747	0.69
127_A	215_D	0.747	0.69
551_A	555_A	0.745	0.69
617_V	651_I	0.745	0.69
23_L	672_D	0.743	0.69
404_A	412_S	0.740	0.69
526_D	550_P	0.739	0.68
113_Q	686_V	0.739	0.68
318_F	343_L	0.738	0.68
22_P	665_Q	0.737	0.68
659_A	724_V	0.737	0.68
455_L	460_L	0.736	0.68
48_L	54_R	0.735	0.68
198_E	213_L	0.735	0.68
599_D	610_A	0.734	0.68
323_G	391_V	0.733	0.68
737_L	748_D	0.733	0.68
609_L	635_H	0.732	0.68
63_T	265_S	0.731	0.68
619_P	640_R	0.731	0.68
684_H	701_R	0.731	0.68
600_W	607_W	0.730	0.68
543_L	560_L	0.729	0.67
35_V	38_A	0.729	0.67
607_W	630_G	0.729	0.67
270_L	632_A	0.729	0.67
322_F	496_G	0.728	0.67
129_W	133_A	0.728	0.67
620_R	628_L	0.728	0.67
259_Q	720_L	0.726	0.67
4_A	35_V	0.725	0.67
100_Q	103_R	0.724	0.67
253_E	256_R	0.724	0.67
157_D	162_I	0.724	0.67
184_L	217_L	0.723	0.67
265_S	718_E	0.723	0.67
609_L	655_P	0.723	0.67
572_A	589_A	0.720	0.66
124_G	215_D	0.719	0.66
186_A	602_E	0.719	0.66
33_E	591_R	0.719	0.66
262_Y	324_V	0.719	0.66
734_E	737_L	0.719	0.66
47_Y	667_Y	0.719	0.66
19_A	25_G	0.718	0.66
328_Y	339_L	0.718	0.66
167_E	280_A	0.718	0.66
737_L	744_R	0.716	0.66
646_S	649_E	0.715	0.66
436_L	439_E	0.715	0.66
737_L	743_V	0.714	0.66
76_P	81_L	0.714	0.66
222_A	225_R	0.713	0.66
255_R	259_Q	0.713	0.66
316_F	414_R	0.713	0.66
68_E	731_E	0.713	0.66
10_P	665_Q	0.712	0.66
23_L	42_F	0.711	0.65
62_I	265_S	0.711	0.65
185_L	675_R	0.711	0.65
288_A	563_D	0.710	0.65
11_Q	24_H	0.710	0.65
100_Q	223_L	0.709	0.65
653_T	736_I	0.709	0.65
363_R	366_R	0.708	0.65
743_V	748_D	0.708	0.65
203_A	210_P	0.708	0.65
184_L	191_A	0.706	0.65
426_P	429_T	0.706	0.65
20_H	708_S	0.706	0.65
360_A	363_R	0.705	0.65
266_Y	632_A	0.705	0.65
37_R	40_R	0.705	0.65
470_L	531_A	0.704	0.65
76_P	80_T	0.704	0.65
377_W	380_F	0.703	0.65
495_P	544_F	0.702	0.64
69_A	264_R	0.700	0.64
723_L	752_L	0.700	0.64
444_L	511_E	0.698	0.64
92_D	95_E	0.697	0.64
316_F	636_S	0.696	0.64
461_T	643_P	0.695	0.64
274_L	725_V	0.695	0.64
161_A	164_E	0.694	0.64
487_D	608_G	0.694	0.64
694_E	697_G	0.693	0.63
316_F	464_F	0.692	0.63
140_E	146_G	0.692	0.63
44_A	672_D	0.692	0.63
358_A	428_R	0.690	0.63
28_D	745_E	0.689	0.63
4_A	181_H	0.688	0.63
643_P	646_S	0.688	0.63
302_F	537_T	0.687	0.63
390_F	398_Y	0.687	0.63
155_P	161_A	0.686	0.63
471_V	543_L	0.685	0.63
674_E	701_R	0.684	0.62
459_G	647_V	0.684	0.62
53_Y	671_V	0.683	0.62
53_Y	502_V	0.683	0.62
742_A	745_E	0.682	0.62
392_E	486_L	0.682	0.62
600_W	609_L	0.682	0.62
366_R	370_R	0.681	0.62
17_F	31_F	0.681	0.62
425_P	429_T	0.681	0.62
257_I	752_L	0.680	0.62
348_H	450_R	0.679	0.62
57_L	62_I	0.679	0.62
105_C	612_N	0.678	0.62
285_A	551_A	0.678	0.62
443_T	447_Q	0.677	0.62
736_I	746_L	0.676	0.62
615_F	630_G	0.675	0.61
732_A	735_A	0.674	0.61
452_E	652_L	0.674	0.61
660_Q	746_L	0.674	0.61
85_L	88_L	0.672	0.61
350_V	502_V	0.671	0.61
474_G	498_P	0.670	0.61
121_R	124_G	0.670	0.61
535_D	678_S	0.668	0.61
316_F	460_L	0.667	0.61
458_M	470_L	0.667	0.61
397_L	400_L	0.667	0.61
467_L	530_V	0.665	0.60
487_D	495_P	0.665	0.60
158_P	162_I	0.665	0.60
562_A	566_E	0.664	0.60
654_A	747_V	0.663	0.60
537_T	610_A	0.662	0.60
325_P	344_L	0.661	0.60
487_D	597_A	0.661	0.60
82_R	92_D	0.660	0.60
336_P	349_L	0.659	0.60
297_V	603_V	0.659	0.60
565_E	569_A	0.658	0.60
742_A	748_D	0.658	0.60
680_S	706_W	0.657	0.59
51_A	58_A	0.657	0.59
431_L	435_R	0.656	0.59
51_A	55_E	0.656	0.59
28_D	174_E	0.654	0.59
318_F	457_A	0.654	0.59
323_G	503_L	0.652	0.59
609_L	615_F	0.651	0.59
144_L	150_R	0.650	0.59
478_V	495_P	0.650	0.59
503_L	506_M	0.649	0.58
375_R	378_H	0.648	0.58
555_A	558_A	0.648	0.58
360_A	364_R	0.647	0.58
270_L	628_L	0.647	0.58
46_G	676_Y	0.645	0.58
150_R	225_R	0.645	0.58
468_V	552_S	0.645	0.58
590_L	594_E	0.644	0.58
609_L	630_G	0.643	0.58
650_L	740_H	0.643	0.58
173_E	517_A	0.642	0.58
85_L	89_T	0.641	0.58
31_F	256_R	0.640	0.57
652_L	743_V	0.640	0.57
367_R	420_G	0.639	0.57
103_R	612_N	0.639	0.57
297_V	708_S	0.638	0.57
38_A	668_F	0.638	0.57
426_P	431_L	0.638	0.57
340_C	503_L	0.637	0.57
619_P	638_D	0.636	0.57
633_F	637_Y	0.636	0.57
32_E	36_A	0.636	0.57
56_A	59_S	0.635	0.57
88_L	92_D	0.634	0.57
297_V	607_W	0.634	0.57
528_W	548_L	0.633	0.57
646_S	650_L	0.632	0.56
98_H	101_L	0.632	0.56
162_I	467_L	0.631	0.56
535_D	597_A	0.631	0.56
318_F	635_H	0.630	0.56
325_P	564_L	0.630	0.56
562_A	726_I	0.630	0.56
611_G	630_G	0.629	0.56
293_F	391_V	0.629	0.56
343_L	653_T	0.629	0.56
55_E	358_A	0.628	0.56
332_G	363_R	0.628	0.56
535_D	540_E	0.628	0.56
672_D	675_R	0.628	0.56
415_L	419_L	0.627	0.56
173_E	525_D	0.627	0.56
340_C	636_S	0.626	0.56
33_E	518_E	0.626	0.56
633_F	663_N	0.626	0.56
325_P	340_C	0.626	0.56
154_L	165_A	0.626	0.56
462_K	525_D	0.625	0.56
577_R	627_D	0.625	0.56
35_V	47_Y	0.624	0.55
410_R	413_A	0.623	0.55
652_L	724_V	0.623	0.55
77_R	82_R	0.621	0.55
143_G	146_G	0.620	0.55
80_T	87_A	0.619	0.55
609_L	627_D	0.619	0.55
661_W	665_Q	0.618	0.55
299_S	609_L	0.617	0.55
4_A	16_D	0.615	0.54
687_V	736_I	0.615	0.54
124_G	127_A	0.614	0.54
109_L	212_T	0.614	0.54
578_R	629_D	0.614	0.54
565_E	738_A	0.614	0.54
693_M	716_I	0.613	0.54
102_I	106_A	0.613	0.54
362_R	447_Q	0.612	0.54
129_W	136_D	0.612	0.54
435_R	438_D	0.612	0.54
574_E	579_L	0.611	0.54
477_S	483_A	0.611	0.54
33_E	51_A	0.610	0.54
108_Y	125_F	0.610	0.54
657_V	661_W	0.609	0.54
160_D	163_A	0.608	0.54
656_M	740_H	0.608	0.54
561_R	727_E	0.607	0.53
77_R	80_T	0.606	0.53
471_V	530_V	0.605	0.53
545_D	548_L	0.605	0.53
5_A	199_W	0.604	0.53
99_P	693_M	0.604	0.53
670_T	708_S	0.604	0.53
340_C	602_E	0.604	0.53
579_L	596_R	0.604	0.53
343_L	470_L	0.604	0.53
462_K	522_D	0.603	0.53
448_A	738_A	0.602	0.53
323_G	534_H	0.602	0.53
104_W	219_V	0.602	0.53
107_A	114_A	0.602	0.53
352_E	699_D	0.602	0.53
223_L	701_R	0.601	0.53
652_L	752_L	0.600	0.53
297_V	661_W	0.600	0.53
330_P	741_P	0.600	0.53
111_Q	603_V	0.600	0.53
129_W	599_D	0.599	0.53
262_Y	265_S	0.599	0.53
478_V	537_T	0.599	0.53
108_Y	179_Y	0.597	0.52
570_L	573_A	0.597	0.52
413_A	598_V	0.596	0.52
63_T	69_A	0.596	0.52
295_I	607_W	0.596	0.52
650_L	654_A	0.595	0.52
215_D	226_A	0.594	0.52
338_P	346_P	0.594	0.52
318_F	650_L	0.594	0.52
475_S	500_A	0.594	0.52
8_I	184_L	0.593	0.52
54_R	58_A	0.593	0.52
462_K	554_R	0.593	0.52
208_A	731_E	0.593	0.52
673_N	706_W	0.593	0.52
580_P	607_W	0.593	0.52
616_I	634_L	0.592	0.52
396_L	400_L	0.592	0.52
14_L	20_H	0.592	0.52
52_E	670_T	0.592	0.52
88_L	91_I	0.592	0.52
94_D	98_H	0.591	0.52
305_H	308_E	0.591	0.52
97_V	626_L	0.591	0.52
193_M	196_W	0.591	0.52
635_H	659_A	0.591	0.52
608_G	665_Q	0.590	0.51
165_A	169_L	0.586	0.51
610_A	695_G	0.586	0.51
683_P	701_R	0.585	0.51
487_D	533_L	0.585	0.51
523_I	629_D	0.585	0.51
11_Q	16_D	0.585	0.51
308_E	578_R	0.585	0.51
683_P	689_L	0.585	0.51
265_S	686_V	0.584	0.51
422_M	425_P	0.583	0.51
167_E	173_E	0.583	0.51
713_D	736_I	0.583	0.51
571_A	608_G	0.582	0.50
393_A	396_L	0.582	0.50
169_L	179_Y	0.582	0.50
297_V	538_T	0.582	0.50
199_W	202_D	0.581	0.50
356_D	445_E	0.579	0.50
394_L	398_Y	0.579	0.50
49_P	52_E	0.579	0.50
37_R	42_F	0.578	0.50
568_G	594_E	0.578	0.50
617_V	726_I	0.578	0.50
615_F	724_V	0.577	0.50
33_E	55_E	0.577	0.50
62_I	67_L	0.577	0.50
350_V	442_F	0.577	0.50
617_V	634_L	0.577	0.50
95_E	470_L	0.576	0.50
648_L	733_I	0.576	0.50
472_G	531_A	0.576	0.50
660_Q	665_Q	0.575	0.50
259_Q	262_Y	0.575	0.50
26_F	31_F	0.575	0.50
683_P	712_G	0.575	0.50
38_A	46_G	0.574	0.49
23_L	47_Y	0.574	0.49
711_D	714_R	0.574	0.49
486_L	495_P	0.573	0.49
295_I	320_G	0.573	0.49
293_F	651_I	0.572	0.49
281_P	552_S	0.572	0.49
331_L	354_P	0.571	0.49
476_S	597_A	0.571	0.49
109_L	113_Q	0.571	0.49
607_W	716_I	0.570	0.49
6_H	11_Q	0.570	0.49
328_Y	374_E	0.570	0.49
382_R	387_G	0.570	0.49
621_S	643_P	0.570	0.49
421_H	431_L	0.569	0.49
85_L	92_D	0.569	0.49
501_R	574_E	0.569	0.49
733_I	742_A	0.569	0.49
275_A	738_A	0.568	0.49
312_G	563_D	0.568	0.49
18_V	297_V	0.567	0.49
433_L	505_A	0.567	0.49
650_L	736_I	0.567	0.49
392_E	600_W	0.566	0.49
393_A	403_L	0.566	0.49
5_A	158_P	0.565	0.48
98_H	102_I	0.565	0.48
515_G	519_R	0.564	0.48
660_Q	694_E	0.564	0.48
511_E	709_V	0.564	0.48
321_F	655_P	0.564	0.48
452_E	516_L	0.564	0.48
730_P	733_I	0.562	0.48
80_T	84_L	0.562	0.48
700_L	707_Q	0.562	0.48
223_L	482_H	0.561	0.48
46_G	49_P	0.561	0.48
300_E	304_R	0.561	0.48
43_G	47_Y	0.560	0.48
517_A	525_D	0.560	0.48
339_L	495_P	0.559	0.48
501_R	547_D	0.559	0.48
532_A	564_L	0.559	0.48
510_P	521_I	0.559	0.48
571_A	630_G	0.559	0.48
94_D	186_A	0.558	0.48
9_P	12_W	0.557	0.47
109_L	211_I	0.557	0.47
362_R	366_R	0.557	0.47
9_P	24_H	0.557	0.47
503_L	603_V	0.556	0.47
11_Q	23_L	0.556	0.47
581_S	602_E	0.556	0.47
573_A	590_L	0.556	0.47
687_V	698_G	0.555	0.47
454_A	470_L	0.555	0.47
174_E	241_A	0.554	0.47
456_R	650_L	0.554	0.47
61_R	265_S	0.553	0.47
355_A	548_L	0.553	0.47
38_A	109_L	0.552	0.47
78_L	84_L	0.552	0.47
682_L	706_W	0.552	0.47
663_N	734_E	0.552	0.47
129_W	161_A	0.552	0.47
487_D	665_Q	0.552	0.47
626_L	672_D	0.551	0.47
748_D	752_L	0.551	0.47
415_L	420_G	0.551	0.47
398_Y	696_N	0.550	0.47
84_L	91_I	0.550	0.47
130_R	222_A	0.549	0.46
288_A	311_P	0.549	0.46
56_A	266_Y	0.549	0.46
249_F	254_R	0.549	0.46
511_E	515_G	0.548	0.46
29_L	34_A	0.548	0.46
481_P	664_L	0.548	0.46
272_A	511_E	0.548	0.46
724_V	743_V	0.548	0.46
617_V	650_L	0.547	0.46
610_A	709_V	0.547	0.46
89_T	231_A	0.547	0.46
740_H	743_V	0.547	0.46
109_L	194_I	0.546	0.46
632_A	692_V	0.546	0.46
34_A	38_A	0.545	0.46
6_H	665_Q	0.545	0.46
295_I	617_V	0.544	0.46
611_G	715_E	0.544	0.46
8_I	302_F	0.543	0.46
654_A	659_A	0.543	0.46
97_V	100_Q	0.543	0.46
568_G	590_L	0.543	0.46
26_F	37_R	0.542	0.46
478_V	483_A	0.542	0.46
146_G	150_R	0.542	0.46
365_R	525_D	0.542	0.46
460_L	464_F	0.542	0.46
427_P	431_L	0.541	0.46
96_L	139_P	0.541	0.46
329_Q	351_K	0.540	0.45
11_Q	20_H	0.539	0.45
148_R	153_A	0.539	0.45
14_L	185_L	0.538	0.45
497_G	544_F	0.538	0.45
109_L	193_M	0.538	0.45
126_Y	130_R	0.538	0.45
653_T	742_A	0.538	0.45
63_T	514_A	0.537	0.45
452_E	464_F	0.537	0.45
609_L	660_Q	0.537	0.45
317_G	633_F	0.537	0.45
432_T	514_A	0.537	0.45
180_L	183_L	0.536	0.45
319_A	472_G	0.536	0.45
68_E	468_V	0.536	0.45
377_W	651_I	0.535	0.45
323_G	696_N	0.535	0.45
486_L	610_A	0.535	0.45
297_V	492_G	0.535	0.45
414_R	510_P	0.535	0.45
299_S	661_W	0.535	0.45
694_E	746_L	0.534	0.45
656_M	752_L	0.534	0.45
327_Y	494_R	0.534	0.45
104_W	128_A	0.534	0.45
611_G	629_D	0.533	0.45
194_I	216_L	0.533	0.45
603_V	607_W	0.532	0.44
215_D	624_R	0.532	0.44
194_I	340_C	0.531	0.44
483_A	487_D	0.531	0.44
286_R	591_R	0.531	0.44
274_L	622_L	0.531	0.44
426_P	433_L	0.531	0.44
366_R	423_F	0.531	0.44
133_A	136_D	0.530	0.44
692_V	705_P	0.530	0.44
299_S	655_P	0.529	0.44
625_G	709_V	0.529	0.44
164_E	168_R	0.529	0.44
434_D	447_Q	0.528	0.44
703_G	707_Q	0.528	0.44
484_S	663_N	0.527	0.44
306_L	532_A	0.525	0.44
160_D	218_A	0.525	0.44
627_D	630_G	0.525	0.44
78_L	88_L	0.525	0.44
646_S	735_A	0.525	0.44
222_A	393_A	0.524	0.43
588_A	652_L	0.524	0.43
404_A	410_R	0.524	0.43
717_H	721_R	0.524	0.43
103_R	132_L	0.524	0.43
321_F	651_I	0.524	0.43
126_Y	158_P	0.523	0.43
57_L	276_A	0.523	0.43
136_D	155_P	0.523	0.43
458_M	461_T	0.522	0.43
129_W	386_S	0.522	0.43
167_E	735_A	0.522	0.43
541_V	567_A	0.522	0.43
29_L	32_E	0.521	0.43
48_L	486_L	0.521	0.43
615_F	657_V	0.521	0.43
478_V	698_G	0.520	0.43
342_V	597_A	0.520	0.43
653_T	720_L	0.520	0.43
295_I	635_H	0.520	0.43
49_P	55_E	0.520	0.43
442_F	450_R	0.519	0.43
166_L	171_I	0.519	0.43
562_A	644_D	0.519	0.43
172_P	214_V	0.519	0.43
728_A	746_L	0.519	0.43
182_R	185_L	0.518	0.43
482_H	694_E	0.518	0.43
274_L	616_I	0.518	0.43
523_I	735_A	0.518	0.43
338_P	345_T	0.518	0.43
263_E	613_A	0.518	0.43
737_L	747_V	0.518	0.43
661_W	708_S	0.518	0.43
381_K	405_R	0.517	0.43
33_E	514_A	0.517	0.43
607_W	715_E	0.517	0.43
391_V	398_Y	0.517	0.43
128_A	350_V	0.516	0.43
449_D	597_A	0.516	0.43
280_A	555_A	0.516	0.43
258_W	535_D	0.516	0.43
664_L	667_Y	0.515	0.42
439_E	522_D	0.515	0.42
325_P	343_L	0.515	0.42
259_Q	576_A	0.515	0.42
376_A	380_F	0.515	0.42
66_D	718_E	0.514	0.42
297_V	483_A	0.514	0.42
285_A	312_G	0.514	0.42
33_E	292_V	0.514	0.42
533_L	607_W	0.513	0.42
589_A	592_H	0.513	0.42
576_A	579_L	0.512	0.42
706_W	710_H	0.512	0.42
392_E	655_P	0.512	0.42
707_Q	717_H	0.512	0.42
383_S	503_L	0.512	0.42
293_F	471_V	0.511	0.42
363_R	426_P	0.511	0.42
137_L	530_V	0.511	0.42
13_P	193_M	0.511	0.42
689_L	701_R	0.511	0.42
319_A	635_H	0.511	0.42
413_A	416_R	0.510	0.42
401_K	405_R	0.510	0.42
539_D	571_A	0.509	0.42
703_G	717_H	0.509	0.42
4_A	184_L	0.509	0.42
165_A	222_A	0.509	0.42
292_V	454_A	0.509	0.42
347_K	446_E	0.509	0.42
633_F	662_I	0.508	0.42
447_Q	451_A	0.508	0.42
326_I	348_H	0.508	0.42
507_A	665_Q	0.507	0.41
178_D	182_R	0.507	0.41
323_G	655_P	0.507	0.41
11_Q	702_T	0.507	0.41
450_R	615_F	0.507	0.41
476_S	495_P	0.507	0.41
285_A	566_E	0.506	0.41
10_P	25_G	0.506	0.41
105_C	194_I	0.506	0.41
31_F	667_Y	0.505	0.41
152_A	532_A	0.505	0.41
448_A	451_A	0.504	0.41
69_A	731_E	0.504	0.41
195_R	213_L	0.503	0.41
609_L	665_Q	0.503	0.41
385_V	389_L	0.502	0.41
16_D	19_A	0.502	0.41
321_F	326_I	0.501	0.41
729_P	733_I	0.501	0.41
138_T	652_L	0.501	0.41
737_L	745_E	0.501	0.41
654_A	657_V	0.501	0.41
25_G	34_A	0.501	0.41
439_E	554_R	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2w3qA	2	0.242	40.4	0.987	Contact Map
2xwsA	2	0.1569	36.9	0.988	Contact Map
3e3iA	6	0.2314	27.4	0.988	Contact Map
3lyhA	2	0.1516	27	0.988	Contact Map
3fauA	3	0.1037	21.6	0.989	Contact Map
2ab1A	1	0.137	21.1	0.989	Contact Map
2ct6A	1	0.117	20.6	0.989	Contact Map
3qd7X	1	0.1529	17.1	0.989	Contact Map
1ym3A	2	0.2008	16.7	0.99	Contact Map
3ipzA	3	0.137	15.9	0.99	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0171 seconds.