GREMLIN Database
Tape_meas_lam_C - Lambda phage tail tape-measure protein (Tape_meas_lam_C)
PFAM: PF09718 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 76 (72)
Sequences: 4937 (4033)
Seq/√Len: 475.3
META: 0.872

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
63_A66_A2.4491.00
55_A65_I2.3301.00
57_S61_D2.2251.00
34_S37_E2.1551.00
71_I74_P2.1461.00
20_D23_K2.1421.00
45_T60_A2.1021.00
50_S53_D1.9581.00
69_Q73_G1.8251.00
61_D64_R1.6991.00
52_K56_D1.6541.00
9_R26_E1.6441.00
67_I70_A1.6271.00
48_K53_D1.5751.00
36_M43_F1.4951.00
55_A59_I1.4541.00
66_A70_A1.4521.00
41_V45_T1.4481.00
29_F36_M1.3721.00
13_D17_S1.3711.00
53_D56_D1.3261.00
9_R13_D1.2961.00
42_D45_T1.2881.00
55_A58_I1.2881.00
54_L58_I1.2841.00
26_E30_T1.2641.00
38_D64_R1.2231.00
21_A25_A1.2171.00
38_D41_V1.2141.00
23_K26_E1.1961.00
58_I65_I1.1901.00
61_D68_Q1.1841.00
56_D60_A1.1371.00
17_S20_D1.1001.00
44_V54_L1.0821.00
37_E41_V1.0611.00
8_K17_S1.0411.00
27_D30_T1.0211.00
8_K12_A1.0121.00
13_D26_E1.0091.00
12_A16_D1.0051.00
55_A61_D0.9921.00
22_A29_F0.9871.00
11_L15_A0.9821.00
5_A9_R0.9781.00
12_A15_A0.9411.00
19_T24_Q0.9371.00
47_G54_L0.9041.00
31_S35_G0.9021.00
5_A8_K0.8831.00
23_K27_D0.8801.00
15_A19_T0.8781.00
41_V44_V0.8761.00
40_L67_I0.8691.00
14_Y18_A0.8451.00
59_I63_A0.8251.00
41_V64_R0.8051.00
4_S8_K0.7971.00
8_K13_D0.7861.00
56_D64_R0.7841.00
25_A28_A0.7831.00
46_T49_L0.7811.00
64_R68_Q0.7741.00
70_A74_P0.7681.00
65_I69_Q0.7631.00
45_T49_L0.7601.00
36_M39_A0.7491.00
60_A64_R0.7491.00
7_A10_A0.7371.00
25_A29_F0.7271.00
9_R12_A0.7251.00
67_I74_P0.7191.00
19_T23_K0.7181.00
62_L66_A0.7131.00
56_D59_I0.7101.00
41_V67_I0.7091.00
66_A69_Q0.7001.00
42_D60_A0.6981.00
15_A21_A0.6711.00
29_F33_F0.6661.00
12_A17_S0.6621.00
45_T63_A0.6511.00
42_D46_T0.6461.00
10_A26_E0.6421.00
66_A72_T0.6291.00
27_D31_S0.6250.99
44_V50_S0.6230.99
45_T56_D0.5940.99
72_T75_L0.5930.99
37_E68_Q0.5860.99
44_V51_F0.5780.99
31_S34_S0.5740.99
70_A73_G0.5680.99
5_A12_A0.5620.99
22_A25_A0.5610.99
65_I72_T0.5610.99
38_D42_D0.5600.99
60_A63_A0.5460.99
48_K57_S0.5430.99
53_D57_S0.5380.98
30_T34_S0.5310.98
18_A22_A0.5250.98
14_Y33_F0.5250.98
16_D19_T0.5180.98
22_A26_E0.5180.98
39_A42_D0.5070.98
14_Y37_E0.5010.98
29_F32_A0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3g1gA 2 0.5132 9.9 0.839 Contact Map
3g21A 2 0.5263 8.9 0.842 Contact Map
3favB 1 0.5789 8 0.846 Contact Map
3ogiB 1 0.6842 7.1 0.849 Contact Map
4lwsB 1 0.5789 6.5 0.852 Contact Map
3h6pC 1 0.4605 6.5 0.852 Contact Map
3gwkC 2 0.7368 5.1 0.859 Contact Map
2vs0A 2 0.6184 5 0.86 Contact Map
2a01A 1 0.8553 4.8 0.86 Contact Map
1d1dA 1 0.9868 4.7 0.861 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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