GREMLIN Database
Tail_P2_I - Phage tail protein (Tail_P2_I)
PFAM: PF09684 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 136 (127)
Sequences: 5344 (4254)
Seq/√Len: 377.5
META: 0.759

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
33_D66_K5.1871.00
37_E58_E5.0711.00
74_R79_A3.3891.00
67_N83_R3.3651.00
57_P60_R3.3411.00
31_D34_T3.1451.00
78_P82_R2.9541.00
79_A83_R2.3951.00
83_R86_E2.3221.00
63_A67_N2.0681.00
93_E109_R2.0081.00
30_F46_W1.9771.00
126_R130_E1.9641.00
41_P61_K1.8731.00
104_Y134_P1.8701.00
95_V107_R1.8151.00
100_Y105_T1.7161.00
59_E63_A1.7091.00
48_G72_H1.6941.00
26_L30_F1.6931.00
67_N70_E1.6401.00
68_A72_H1.6321.00
58_E62_R1.6321.00
49_V68_A1.6171.00
70_E74_R1.5861.00
121_T124_R1.5011.00
95_V109_R1.4841.00
118_T121_T1.4841.00
100_Y107_R1.4801.00
74_R83_R1.4381.00
48_G75_R1.3781.00
50_D75_R1.2981.00
119_E123_A1.2921.00
9_E13_A1.2761.00
13_A16_L1.2561.00
85_L125_L1.2031.00
47_L69_I1.1911.00
18_R21_D1.1881.00
14_A18_R1.1701.00
124_R127_R1.1651.00
74_R80_A1.1411.00
42_W45_W1.1381.00
70_E79_A1.1351.00
49_V64_L1.1281.00
44_A52_W1.1221.00
71_L87_A1.1001.00
36_P39_F1.0961.00
86_E91_G1.0921.00
28_A34_T1.0871.00
69_I73_R1.0801.00
40_L58_E1.0681.00
85_L92_V1.0621.00
67_N71_L1.0561.00
15_A20_D1.0541.00
53_D124_R1.0501.00
18_R23_P1.0441.00
16_L20_D1.0391.00
106_F133_K1.0171.00
13_A20_D1.0121.00
102_E105_T0.9811.00
122_Y126_R0.9791.00
67_N87_A0.9711.00
32_P35_C0.9661.00
96_E134_P0.9601.00
64_L84_A0.9561.00
19_L23_P0.9421.00
78_P94_I0.9371.00
10_R13_A0.9321.00
129_I133_K0.9251.00
56_W60_R0.9241.00
130_E133_K0.9211.00
25_P28_A0.9151.00
40_L65_I0.8921.00
52_W61_K0.8901.00
47_L65_I0.8891.00
14_A17_A0.8841.00
17_A20_D0.8781.00
31_D35_C0.8671.00
16_L19_L0.8621.00
70_E73_R0.8481.00
13_A18_R0.8341.00
116_G119_E0.8331.00
56_W61_K0.8311.00
37_E65_I0.8281.00
15_A18_R0.8231.00
82_R86_E0.8151.00
70_E83_R0.8101.00
37_E61_K0.8041.00
80_A132_A0.8011.00
60_R63_A0.7991.00
118_T122_Y0.7891.00
14_A19_L0.7871.00
87_A90_G0.7821.00
108_V129_I0.7781.00
56_W64_L0.7661.00
15_A19_L0.7651.00
33_D63_A0.7641.00
14_A20_D0.7621.00
82_R94_I0.7591.00
20_D23_P0.7571.00
12_L15_A0.7531.00
26_L39_F0.7511.00
58_E61_K0.7481.00
56_W88_L0.7391.00
33_D62_R0.7361.00
30_F35_C0.7351.00
104_Y108_V0.7341.00
117_I122_Y0.7291.00
19_L24_V0.7241.00
17_A21_D0.7221.00
123_A126_R0.7211.00
81_L85_L0.7141.00
106_F113_S0.7111.00
63_A66_K0.7111.00
60_R64_L0.7101.00
85_L90_G0.7091.00
125_L129_I0.7081.00
12_L16_L0.7020.99
35_C39_F0.6930.99
128_L132_A0.6900.99
13_A17_A0.6890.99
30_F47_L0.6880.99
78_P99_E0.6820.99
52_W56_W0.6760.99
84_A128_L0.6650.99
93_E111_D0.6650.99
123_A127_R0.6630.99
20_D24_V0.6620.99
13_A19_L0.6500.99
41_P52_W0.6480.99
79_A82_R0.6390.99
11_A17_A0.6290.99
51_R56_W0.6260.99
35_C46_W0.6210.99
120_E124_R0.6180.99
10_R14_A0.6160.99
78_P96_E0.6160.99
124_R128_L0.6140.99
18_R22_L0.6100.99
32_P62_R0.6060.98
22_L25_P0.6050.98
117_I120_E0.6030.98
72_H75_R0.6020.98
75_R132_A0.6020.98
101_G107_R0.5970.98
51_R71_L0.5940.98
14_A21_D0.5940.98
53_D56_W0.5920.98
83_R87_A0.5910.98
9_E16_L0.5880.98
11_A19_L0.5780.98
109_R113_S0.5780.98
117_I121_T0.5750.98
107_R110_V0.5750.98
119_E122_Y0.5740.98
35_C58_E0.5690.98
64_L71_L0.5680.98
27_R30_F0.5670.98
16_L23_P0.5630.98
116_G121_T0.5620.98
29_L46_W0.5550.97
47_L68_A0.5500.97
46_W69_I0.5500.97
63_A89_G0.5490.97
64_L87_A0.5470.97
42_W56_W0.5470.97
114_D118_T0.5430.97
21_D25_P0.5420.97
15_A25_P0.5410.97
15_A23_P0.5400.97
85_L94_I0.5380.97
90_G111_D0.5350.97
14_A22_L0.5310.97
98_F104_Y0.5290.96
15_A22_L0.5270.96
125_L128_L0.5270.96
16_L24_V0.5230.96
11_A20_D0.5200.96
9_E20_D0.5150.96
82_R93_E0.5120.96
103_P108_V0.5120.96
127_R131_A0.5120.96
120_E123_A0.5120.96
85_L110_V0.5110.96
28_A32_P0.5110.96
58_E65_I0.5100.96
111_D115_R0.5090.96
19_L25_P0.5080.96
42_W46_W0.5030.95
71_L132_A0.5000.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1h2vC 1 0.8971 13 0.912 Contact Map
1hf2A 2 0.4559 8.3 0.92 Contact Map
2m4iA 1 0.5588 7 0.922 Contact Map
1vzyA 3 0.8162 4.6 0.929 Contact Map
4u5rA 3 0.6544 4.5 0.929 Contact Map
2qgqA 1 0.8382 4.3 0.93 Contact Map
1dq3A 1 0.9926 4.2 0.93 Contact Map
3peiA 5 0.5809 4.1 0.931 Contact Map
1oltA 1 0.8603 4.1 0.931 Contact Map
3or1B 2 0.6691 4 0.931 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0062 seconds.