GREMLIN Database
Spore_YhcN_YlaJ - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PFAM: PF09580 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 182 (176)
Sequences: 928 (827)
Seq/√Len: 62.4
META: 0.392

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
115_V129_V3.7081.00
130_K134_K3.0001.00
116_D147_D2.9611.00
115_V146_T2.8761.00
93_V129_V2.7531.00
94_A102_A2.6031.00
114_A154_I2.5991.00
100_D116_D2.5771.00
93_V96_L2.5211.00
165_R168_E2.3931.00
160_D165_R2.2881.00
90_A104_V2.2661.00
177_M181_I2.1151.00
86_A90_A2.1141.00
173_E180_R2.0621.00
28_G32_N1.9671.00
174_I178_I1.9151.00
93_V99_V1.8981.00
111_A137_D1.8921.00
114_A145_S1.8761.00
89_I133_V1.8411.00
98_G125_L1.8391.00
169_G173_E1.8351.00
126_K146_T1.8151.00
85_L137_D1.7921.00
105_L154_I1.7881.00
93_V132_A1.7340.99
116_D151_F1.6750.99
2_L5_L1.6740.99
98_G128_K1.6580.99
96_L99_V1.6520.99
63_Q66_N1.6440.99
39_G42_N1.6180.99
132_A135_S1.5920.99
97_P138_P1.5850.99
133_V142_V1.5810.99
110_N141_N1.5600.99
145_S150_L1.5460.99
3_L7_G1.5220.98
98_G111_A1.4420.98
62_Y66_N1.4300.98
59_Y63_Q1.4270.98
169_G180_R1.4220.98
153_R173_E1.4190.98
41_Y44_N1.4180.98
153_R176_E1.3830.97
82_R108_D1.3750.97
59_Y64_N1.3620.97
100_D163_N1.3540.97
125_L129_V1.3340.96
33_V36_N1.3200.96
144_V151_F1.2850.96
85_L89_I1.2770.95
145_S157_Y1.2670.95
49_T53_N1.2610.95
13_N16_D1.2400.95
85_L143_Y1.2350.95
10_N14_A1.2210.94
112_L157_Y1.2050.94
60_V66_N1.2020.94
46_N52_N1.1930.94
59_Y62_Y1.1890.93
85_L106_V1.1800.93
58_G61_R1.1790.93
14_A17_N1.1680.93
86_A105_L1.1680.93
40_P44_N1.1660.93
110_N143_Y1.1650.93
30_T34_N1.1640.93
38_N44_N1.1490.92
13_N17_N1.1350.92
26_N29_N1.1300.92
115_V126_K1.1280.91
28_G33_V1.1220.91
96_L132_A1.1160.91
48_D51_D1.1120.91
138_P181_I1.1050.91
45_N50_N1.1030.91
30_T33_V1.0970.90
112_L150_L1.0970.90
173_E177_M1.0950.90
107_T112_L1.0930.90
166_P170_F1.0890.90
82_R85_L1.0890.90
27_S48_D1.0740.89
92_R132_A1.0660.89
112_L174_I1.0540.88
157_Y160_D1.0530.88
154_I174_I1.0530.88
108_D135_S1.0510.88
107_T169_G1.0490.88
98_G117_L1.0450.88
174_I177_M1.0390.88
160_D169_G1.0360.88
170_F181_I1.0270.87
129_V137_D1.0260.87
112_L145_S1.0090.86
7_G38_N1.0050.86
122_T146_T0.9980.85
46_N51_D0.9910.85
104_V174_I0.9850.85
37_N43_D0.9850.85
103_A151_F0.9660.84
65_N70_N0.9590.83
109_N140_Y0.9530.83
29_N33_V0.9490.82
28_G31_T0.9450.82
43_D47_N0.9450.82
10_N13_N0.9410.82
105_L179_R0.9380.82
161_I164_G0.9330.81
112_L130_K0.9310.81
5_L8_C0.9160.80
111_A145_S0.9060.79
166_P169_G0.9010.79
61_R64_N0.8990.79
47_N50_N0.8960.79
158_A162_R0.8880.78
111_A146_T0.8790.77
11_N14_A0.8790.77
48_D163_N0.8740.77
93_V104_V0.8740.77
81_N140_Y0.8730.77
17_N20_N0.8610.76
27_S32_N0.8600.76
90_A94_A0.8570.76
114_A150_L0.8570.76
145_S151_F0.8510.75
82_R107_T0.8440.74
126_K150_L0.8420.74
62_Y65_N0.8250.73
86_A106_V0.8190.72
147_D150_L0.8180.72
6_T9_G0.8060.71
47_N69_N0.8040.71
160_D164_G0.8020.71
45_N49_T0.7990.70
31_T35_N0.7970.70
143_Y157_Y0.7960.70
148_P157_Y0.7900.69
57_F61_R0.7820.69
29_N32_N0.7820.69
40_P47_N0.7780.68
37_N40_P0.7770.68
40_P48_D0.7750.68
175_N179_R0.7520.66
113_V149_D0.7500.65
33_V41_Y0.7490.65
92_R95_K0.7480.65
112_L171_F0.7470.65
146_T173_E0.7430.65
31_T50_N0.7430.65
32_N37_N0.7430.65
32_N48_D0.7430.65
85_L171_F0.7410.64
87_D91_D0.7400.64
40_P46_N0.7380.64
106_V111_A0.7280.63
67_N71_N0.7240.63
110_N114_A0.7200.62
3_L6_T0.7200.62
36_N43_D0.7160.62
16_D19_N0.7090.61
42_N45_N0.7060.61
27_S31_T0.7010.60
59_Y68_D0.6970.60
82_R112_L0.6970.60
73_N120_K0.6930.59
4_L7_G0.6920.59
82_R143_Y0.6910.59
91_D112_L0.6860.59
112_L143_Y0.6840.58
168_E173_E0.6730.57
99_V125_L0.6700.57
18_N25_N0.6700.57
90_A103_A0.6660.56
65_N73_N0.6640.56
39_G44_N0.6580.55
47_N80_N0.6560.55
7_G10_N0.6560.55
9_G15_N0.6480.54
45_N52_N0.6430.54
6_T76_N0.6410.53
39_G48_D0.6400.53
48_D159_N0.6390.53
96_L129_V0.6380.53
122_T129_V0.6350.53
111_A173_E0.6320.52
32_N42_N0.6300.52
175_N178_I0.6280.52
126_K147_D0.6230.51
118_D138_P0.6200.51
12_N17_N0.6170.51
171_F175_N0.6170.51
48_D53_N0.6160.51
31_T34_N0.6090.50
44_N51_D0.6060.49
15_N18_N0.6060.49
56_G61_R0.6040.49
44_N47_N0.6030.49
4_L13_N0.6020.49
38_N41_Y0.6020.49
131_K168_E0.6020.49
33_V38_N0.6000.49
6_T114_A0.5970.48
25_N28_G0.5960.48
37_N46_N0.5960.48
112_L147_D0.5930.48
60_V64_N0.5920.48
166_P180_R0.5890.48
89_I142_V0.5890.48
16_D20_N0.5870.47
25_N30_T0.5840.47
105_L170_F0.5830.47
126_K131_K0.5810.47
130_K147_D0.5780.46
130_K174_I0.5780.46
3_L144_V0.5770.46
145_S158_A0.5750.46
83_E105_L0.5720.46
103_A106_V0.5700.45
115_V160_D0.5680.45
34_N37_N0.5670.45
143_Y150_L0.5660.45
129_V140_Y0.5650.45
66_N73_N0.5650.45
101_D146_T0.5650.45
61_R65_N0.5640.45
119_D152_D0.5630.45
45_N48_D0.5630.45
34_N40_P0.5590.44
103_A112_L0.5580.44
38_N45_N0.5570.44
122_T126_K0.5560.44
9_G12_N0.5550.44
34_N91_D0.5540.44
40_P53_N0.5500.43
57_F60_V0.5490.43
60_V65_N0.5470.43
40_P50_N0.5450.43
128_K131_K0.5430.42
78_N83_E0.5410.42
4_L56_G0.5410.42
47_N52_N0.5410.42
63_Q68_D0.5400.42
30_T40_P0.5370.42
97_P135_S0.5360.42
73_N78_N0.5360.42
46_N49_T0.5250.40
103_A145_S0.5240.40
126_K134_K0.5240.40
5_L98_G0.5220.40
130_K140_Y0.5210.40
107_T180_R0.5210.40
108_D113_V0.5210.40
68_D73_N0.5180.40
41_Y46_N0.5180.40
31_T38_N0.5160.39
29_N35_N0.5140.39
41_Y49_T0.5140.39
154_I181_I0.5100.39
30_T37_N0.5060.38
100_D118_D0.5050.38
123_D126_K0.5000.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4q2lA 1 0.3516 77.1 0.875 Contact Map
2ru9A 1 0.3846 74.6 0.877 Contact Map
2g9oA 1 0.4176 39.5 0.902 Contact Map
3j09A 2 0.489 33.7 0.905 Contact Map
1q8lA 1 0.4615 33.7 0.905 Contact Map
1y3jA 1 0.4231 31 0.907 Contact Map
1kviA 1 0.4341 30.6 0.907 Contact Map
1opzA 1 0.4176 26.5 0.91 Contact Map
4oycA 1 0.4121 26.4 0.91 Contact Map
1fvqA 1 0.3956 26.3 0.91 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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