GREMLIN Database
Spore_YunB - Sporulation protein YunB (Spo_YunB)
PFAM: PF09560 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 91 (90)
Sequences: 2591 (1999)
Seq/√Len: 210.7
META: 0.811

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
37_K55_E3.6271.00
39_E51_R3.4431.00
57_E72_E3.4101.00
55_E74_S3.0211.00
55_E76_E2.8901.00
57_E74_S2.7391.00
59_E72_E2.5971.00
3_S21_K2.2351.00
37_K76_E2.0751.00
59_E70_E1.9981.00
41_E49_R1.9601.00
35_D55_E1.9421.00
53_Y78_P1.7391.00
61_R70_E1.7191.00
33_E57_E1.6871.00
34_T56_V1.6861.00
49_R81_E1.6801.00
41_E51_R1.6131.00
50_H81_E1.5661.00
81_E85_V1.5491.00
40_F48_T1.5391.00
53_Y76_E1.5131.00
43_A48_T1.5051.00
78_P81_E1.4741.00
40_F81_E1.4431.00
40_F50_H1.3321.00
38_S53_Y1.2841.00
8_Q16_A1.2831.00
82_T85_V1.2791.00
61_R68_S1.2551.00
37_K53_Y1.2301.00
3_S23_P1.2131.00
35_D76_E1.1921.00
10_T13_P1.1721.00
47_Q85_V1.1071.00
7_G19_G1.0511.00
38_S52_I1.0491.00
87_D90_D1.0381.00
49_R83_V1.0251.00
48_T85_V1.0161.00
54_L79_I1.0141.00
38_S50_H0.9821.00
43_A85_V0.9771.00
51_R81_E0.9751.00
43_A81_E0.9711.00
44_G47_Q0.9480.99
36_F79_I0.9370.99
6_L20_P0.9190.99
47_Q50_H0.9130.99
35_D57_E0.8720.99
47_Q81_E0.8690.99
17_G61_R0.8510.99
86_G89_P0.8460.99
40_F43_A0.8450.99
8_Q18_L0.8340.99
8_Q13_P0.8320.99
17_G27_I0.8260.99
52_I80_A0.8150.98
38_S49_R0.8070.98
28_P63_I0.7980.98
23_P34_T0.7940.98
28_P31_S0.7860.98
32_V56_V0.7850.98
40_F83_V0.7850.98
12_S17_G0.7800.98
4_I8_Q0.7780.98
43_A52_I0.7750.98
40_F47_Q0.7740.98
8_Q11_G0.7730.98
10_T15_L0.7660.98
7_G10_T0.7570.98
15_L18_L0.7500.97
38_S51_R0.7330.97
50_H80_A0.7310.97
39_E76_E0.7200.97
54_L68_S0.7190.97
17_G25_K0.7150.97
25_K69_E0.7060.96
54_L62_I0.6980.96
8_Q36_F0.6890.96
33_E80_A0.6860.96
67_A77_V0.6860.96
43_A47_Q0.6750.95
30_G52_I0.6710.95
10_T19_G0.6610.95
58_V75_T0.6610.95
28_P32_V0.6540.94
39_E53_Y0.6500.94
30_G60_V0.6430.94
18_L21_K0.6420.94
60_V71_I0.6370.93
20_P52_I0.6220.93
69_E72_E0.6190.93
13_P24_V0.6170.92
50_H83_V0.6170.92
43_A82_T0.6080.92
9_L51_R0.6070.92
47_Q83_V0.6030.92
43_A50_H0.6010.91
33_E59_E0.5970.91
60_V65_P0.5930.91
6_L21_K0.5860.90
27_I63_I0.5840.90
9_L22_I0.5820.90
43_A49_R0.5800.90
16_A29_V0.5790.90
23_P27_I0.5790.90
67_A79_I0.5780.90
56_V77_V0.5780.90
28_P64_I0.5770.90
10_T18_L0.5690.89
36_F77_V0.5670.89
28_P40_F0.5650.89
23_P28_P0.5650.89
13_P36_F0.5630.89
38_S82_T0.5610.88
63_I68_S0.5600.88
16_A19_G0.5580.88
25_K36_F0.5480.87
62_I69_E0.5460.87
32_V58_V0.5460.87
28_P62_I0.5440.87
36_F39_E0.5440.87
9_L78_P0.5350.86
4_I75_T0.5310.85
21_K59_E0.5210.84
50_H82_T0.5180.84
7_G45_I0.5150.84
26_I68_S0.5140.84
40_F82_T0.5120.83
66_F69_E0.5110.83
26_I64_I0.5100.83
50_H85_V0.5090.83
62_I71_I0.5030.82
13_P69_E0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2y26A 8 0.5495 3.9 0.922 Contact Map
1ou8A 2 0.3297 2.4 0.93 Contact Map
4kq7A 4 0.7473 1.9 0.934 Contact Map
3napB 4 0.6923 1.7 0.935 Contact Map
2lr4A 1 0.3846 1.6 0.937 Contact Map
1wc3A 2 0.8791 1.3 0.939 Contact Map
4jk8A 1 0.9451 1.2 0.941 Contact Map
1a6cA 6 0.5385 1.1 0.942 Contact Map
3gd0A 1 0.8901 1.1 0.943 Contact Map
3ogzA 1 0.9011 1 0.943 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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