GREMLIN Database
Phage_TAC_6 - Phage tail assembly chaperone protein, TAC
PFAM: PF09550 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 58 (56)
Sequences: 3377 (2463)
Seq/√Len: 329.2
META: 0.886

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_S20_E4.1511.00
16_L24_L3.6731.00
44_D47_E2.8591.00
19_D23_A2.6701.00
47_E50_A2.5351.00
7_M11_L2.4861.00
43_L48_L1.8041.00
9_A13_V1.7491.00
14_L32_A1.7391.00
24_L32_A1.5781.00
49_E52_M1.5341.00
10_G29_L1.5151.00
2_P5_A1.4661.00
9_A33_L1.3711.00
50_A54_R1.3061.00
6_L29_L1.2541.00
48_L52_M1.2431.00
45_R49_E1.2281.00
43_L47_E1.1791.00
3_W28_E1.1581.00
50_A53_A1.1371.00
46_A49_E1.1181.00
12_G32_A1.0901.00
7_M31_A1.0681.00
25_T29_L1.0641.00
26_P29_L1.0531.00
49_E53_A1.0231.00
30_A34_G0.9741.00
10_G16_L0.9441.00
51_L55_F0.9431.00
22_W28_E0.9151.00
4_P8_R0.8471.00
26_P30_A0.8411.00
8_R12_G0.8391.00
8_R34_G0.8051.00
8_R13_V0.7981.00
34_G39_G0.7901.00
4_P34_G0.7591.00
6_L21_F0.7550.99
40_A46_A0.7530.99
16_L25_T0.7530.99
2_P6_L0.7520.99
18_P24_L0.7460.99
47_E54_R0.7320.99
25_T30_A0.7210.99
45_R52_M0.7210.99
35_A38_G0.7200.99
8_R36_L0.7150.99
10_G14_L0.7130.99
15_G36_L0.7130.99
5_A8_R0.7050.99
30_A33_L0.6980.99
27_R31_A0.6940.99
11_L15_G0.6800.99
3_W6_L0.6460.98
44_D52_M0.6420.98
2_P31_A0.6330.98
24_L29_L0.6250.98
21_F29_L0.6180.98
47_E51_L0.6170.98
35_A39_G0.6030.98
22_W26_P0.6010.97
12_G31_A0.6000.97
31_A34_G0.5980.97
9_A12_G0.5950.97
11_L16_L0.5890.97
11_L18_P0.5800.97
11_L17_S0.5720.97
6_L30_A0.5660.96
7_M10_G0.5500.96
47_E52_M0.5500.96
5_A12_G0.5380.95
36_L41_A0.5300.95
12_G52_M0.5300.95
13_V55_F0.5270.95
17_S24_L0.5260.95
27_R30_A0.5230.94
34_G45_R0.5210.94
21_F47_E0.5170.94
19_D41_A0.5110.94
32_A36_L0.5080.94
2_P26_P0.5030.93
43_L46_A0.5020.93
45_R48_L0.5000.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qyhB 1 0.931 19.9 0.839 Contact Map
4zgjB 2 0.9483 13.2 0.852 Contact Map
1j3bA 2 0.8621 13.2 0.852 Contact Map
3hhtB 2 0.9483 12.8 0.853 Contact Map
4muoA 2 0.6034 10.6 0.858 Contact Map
3thgA 2 0.6034 10.5 0.858 Contact Map
4ob0B 1 0.9483 8.7 0.863 Contact Map
2guzB 1 0.6034 8.7 0.863 Contact Map
1iv8A 1 0.9138 8.1 0.865 Contact Map
3u52A 2 1 8.1 0.865 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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