GREMLIN Database
Cas_TM1802 - CRISPR-associated protein TM1802 (cas_TM1802)
PFAM: PF09484 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 609 (596)
Sequences: 930 (839)
Seq/√Len: 34.4
META: 0.81

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
206_C249_C8.0321.00
249_C252_C7.9741.00
206_C252_C7.8381.00
461_A600_F5.8151.00
6_K10_E5.0361.00
541_K558_E4.9771.00
543_N551_D4.8991.00
268_S342_Y4.6041.00
10_E255_K4.3921.00
50_F143_E4.1941.00
518_L559_V4.0581.00
530_Y536_K3.9601.00
522_T559_V3.9381.00
373_K470_K3.8961.00
367_I467_F3.8241.00
521_L563_L3.7361.00
238_D241_N3.6991.00
562_K565_Q3.5601.00
561_N565_Q3.5391.00
35_Y61_E3.5011.00
436_F461_A3.1511.00
554_R558_E3.0511.00
346_D349_A2.9791.00
76_G80_G2.8851.00
136_N139_K2.8801.00
432_L436_F2.8331.00
536_K539_L2.7901.00
241_N244_K2.7851.00
507_D512_K2.7801.00
549_E553_K2.6561.00
235_S245_N2.6241.00
367_I471_L2.6021.00
229_D232_G2.5581.00
338_N355_L2.5291.00
92_E95_K2.5111.00
268_S275_N2.5041.00
13_L255_K2.4941.00
552_I598_I2.4801.00
515_L552_I2.4341.00
270_R275_N2.3450.99
547_M599_S2.3070.99
477_G480_M2.2750.99
230_K233_F2.2690.99
63_D66_K2.2320.99
203_C252_C2.1590.99
515_L547_M2.1480.99
395_I417_I2.1350.99
371_K375_D2.1320.99
37_L147_K2.0720.99
262_Y267_L2.0630.98
555_L559_V2.0370.98
515_L598_I2.0180.98
511_E591_W2.0010.98
96_T100_K1.9780.98
279_I340_L1.9580.98
124_L417_I1.9550.98
530_Y534_G1.9520.98
82_N87_S1.9300.98
264_E277_Y1.9240.98
342_Y350_F1.9090.97
79_N82_N1.9040.97
552_I602_F1.9000.97
548_D595_P1.8970.97
74_K77_S1.8880.97
532_K568_K1.8860.97
419_D423_T1.8850.97
82_N88_K1.8840.97
146_E150_E1.8750.97
228_T234_A1.8710.97
363_R424_G1.8600.97
462_L604_L1.8550.97
440_I458_V1.8530.97
526_L538_F1.8520.97
582_K586_D1.8410.97
417_I427_I1.8140.97
542_L545_L1.7720.96
203_C206_C1.7680.96
107_L110_L1.7660.96
427_I513_K1.7600.96
339_F359_V1.7480.96
269_F278_L1.7470.96
401_V410_K1.7400.96
40_N167_G1.7300.95
203_C249_C1.7230.95
509_S512_K1.7130.95
405_K410_K1.7060.95
6_K255_K1.7040.95
97_L102_L1.7010.95
308_K311_K1.6970.95
379_K382_F1.6950.95
84_T88_K1.6810.95
526_L606_M1.6760.95
480_M484_E1.6730.94
23_D26_I1.6690.94
370_A374_V1.6380.94
234_A242_A1.6330.94
511_E552_I1.6330.94
5_I259_G1.6320.94
410_K413_K1.6240.94
401_V408_F1.6200.93
370_A373_K1.6130.93
547_M552_I1.6100.93
408_F411_Y1.6050.93
147_K150_E1.6040.93
42_D49_E1.6020.93
144_L417_I1.5990.93
128_K132_K1.5810.93
276_Y341_F1.5740.92
174_E178_K1.5660.92
498_F502_Y1.5630.92
598_I606_M1.5240.91
391_N394_T1.5110.91
502_Y506_F1.5080.91
429_Y433_I1.4870.90
340_L355_L1.4850.90
38_V164_K1.4840.90
547_M598_I1.4770.90
367_I421_I1.4710.90
536_K575_E1.4710.90
600_F604_L1.4650.89
261_K265_E1.4590.89
5_I263_I1.4580.89
580_I583_Y1.4560.89
377_L470_K1.4450.89
28_N62_F1.4240.88
548_D554_R1.4180.88
421_I468_L1.4140.88
570_Y573_Y1.4130.88
201_G213_V1.4090.87
43_L166_D1.4080.87
498_F503_L1.4010.87
165_I172_D1.3990.87
441_R444_F1.3970.87
77_S80_G1.3960.87
23_D62_F1.3940.87
42_D51_D1.3850.87
262_Y266_N1.3820.86
30_K33_Y1.3780.86
471_L474_L1.3770.86
100_K104_W1.3760.86
267_L341_F1.3610.86
84_T87_S1.3570.85
78_A85_P1.3420.85
313_L316_R1.3370.85
40_N164_K1.3360.84
405_K411_Y1.3350.84
50_F53_V1.3330.84
139_K143_E1.3310.84
110_L113_K1.3300.84
511_E514_A1.3080.83
366_K370_A1.3040.83
89_T96_T1.2990.83
542_L602_F1.2930.82
371_K467_F1.2910.82
370_A429_Y1.2900.82
308_K367_I1.2880.82
319_S323_E1.2870.82
403_K410_K1.2850.82
107_L111_K1.2810.82
293_I301_K1.2770.82
84_T89_T1.2650.81
537_P565_Q1.2620.81
541_K555_L1.2520.80
51_D488_K1.2520.80
79_N86_T1.2510.80
234_A239_K1.2490.80
523_Q606_M1.2490.80
373_K376_K1.2470.80
523_Q527_N1.2470.80
85_P89_T1.2450.80
575_E578_E1.2400.80
585_L604_L1.2340.79
263_I267_L1.2310.79
560_Q607_S1.2280.79
78_A348_S1.2280.79
38_V162_T1.2260.79
143_E146_E1.2230.79
215_G257_E1.2140.78
525_L559_V1.2130.78
112_K129_K1.2100.78
548_D551_D1.2090.78
404_K408_F1.2030.78
82_N170_L1.2020.78
43_L48_I1.1990.77
27_E74_K1.1970.77
509_S593_L1.1920.77
262_Y547_M1.1790.76
35_Y72_Y1.1770.76
543_N599_S1.1690.76
87_S547_M1.1680.75
323_E326_E1.1660.75
200_N209_K1.1640.75
343_E346_D1.1520.74
344_R347_Q1.1480.74
576_L580_I1.1440.74
70_Y74_K1.1430.74
213_V432_L1.1420.74
414_F418_V1.1400.74
200_N427_I1.1400.74
133_E138_E1.1360.73
6_K205_I1.1320.73
246_F438_E1.1320.73
168_K173_I1.1310.73
367_I473_L1.1260.73
395_I399_F1.1250.73
464_L468_L1.1230.73
343_E409_D1.1230.73
551_D599_S1.1190.72
515_L604_L1.1190.72
499_F503_L1.1160.72
499_F506_F1.1160.72
297_L359_V1.1110.72
20_D263_I1.1110.72
145_K149_K1.1090.72
69_K172_D1.1070.71
97_L104_W1.1060.71
198_A201_G1.1030.71
581_S587_A1.1020.71
454_L458_V1.1020.71
42_D45_N1.0990.71
82_N85_P1.0980.71
62_F160_L1.0980.71
557_P581_S1.0980.71
404_K412_K1.0950.71
324_I493_E1.0930.70
526_L539_L1.0890.70
577_E580_I1.0870.70
401_V406_G1.0860.70
570_Y577_E1.0850.70
113_K129_K1.0810.70
517_L563_L1.0810.70
16_K19_K1.0800.70
131_L163_L1.0800.70
218_S224_K1.0750.69
51_D183_K1.0700.69
117_S168_K1.0650.68
9_G259_G1.0650.68
546_G606_M1.0650.68
401_V404_K1.0640.68
181_L339_F1.0610.68
161_L343_E1.0600.68
224_K246_F1.0600.68
214_Y253_A1.0580.68
159_V162_T1.0580.68
256_L421_I1.0570.68
345_K350_F1.0570.68
186_E190_E1.0430.67
36_V70_Y1.0420.67
236_G367_I1.0390.66
476_G480_M1.0380.66
534_G537_P1.0350.66
94_E145_K1.0350.66
234_A537_P1.0340.66
374_V395_I1.0320.66
229_D467_F1.0310.66
366_K424_G1.0310.66
20_D41_F1.0300.66
116_L121_K1.0290.66
60_E70_Y1.0250.65
502_Y591_W1.0200.65
356_I422_F1.0160.65
204_S247_P1.0160.65
22_L27_E1.0150.65
600_F605_G1.0140.65
208_E211_E1.0120.64
402_R405_K1.0120.64
538_F606_M1.0110.64
522_T555_L1.0100.64
581_S585_L1.0070.64
33_Y88_K1.0060.64
8_I263_I1.0040.64
42_D46_G1.0040.64
163_L170_L1.0020.64
225_F352_I0.9990.63
587_A591_W0.9960.63
180_L216_F0.9960.63
390_F398_F0.9960.63
290_L297_L0.9950.63
291_E479_K0.9940.63
297_L300_L0.9880.63
392_F421_I0.9880.63
271_F276_Y0.9850.62
588_G591_W0.9840.62
210_K251_D0.9800.62
356_I372_E0.9780.62
568_K571_Y0.9760.62
596_D599_S0.9730.61
234_A565_Q0.9720.61
229_D362_S0.9690.61
2_I9_G0.9690.61
574_R578_E0.9690.61
289_D294_L0.9680.61
283_L525_L0.9670.61
429_Y465_L0.9650.61
367_I468_L0.9630.61
314_K372_E0.9610.60
439_K457_S0.9550.60
75_V78_A0.9540.60
523_Q536_K0.9510.60
339_F595_P0.9500.59
267_L361_P0.9500.59
178_K494_K0.9490.59
79_N84_T0.9480.59
236_G414_F0.9450.59
90_T100_K0.9430.59
174_E377_L0.9410.59
6_K252_C0.9410.59
97_L144_L0.9370.58
535_S574_R0.9360.58
4_A7_E0.9320.58
599_S602_F0.9310.58
392_F418_V0.9300.58
10_E127_I0.9290.58
361_P562_K0.9240.57
378_F391_N0.9200.57
434_K596_D0.9160.57
237_F522_T0.9130.56
401_V405_K0.9120.56
570_Y574_R0.9110.56
374_V466_L0.9090.56
599_S606_M0.9090.56
1_M9_G0.9050.56
311_K366_K0.9040.56
514_A559_V0.9030.56
516_F608_L0.9000.55
436_F465_L0.8980.55
556_L598_I0.8980.55
36_V504_D0.8980.55
122_E125_K0.8970.55
599_S603_L0.8950.55
306_L309_L0.8940.55
417_I421_I0.8940.55
64_E356_I0.8940.55
481_E484_E0.8920.55
294_L297_L0.8910.55
260_K507_D0.8870.54
580_I584_L0.8850.54
172_D594_S0.8840.54
238_D283_L0.8820.54
515_L602_F0.8820.54
277_Y342_Y0.8790.54
11_Y14_E0.8790.54
229_D517_L0.8790.54
264_E345_K0.8780.53
45_N51_D0.8770.53
406_G438_E0.8770.53
223_F233_F0.8720.53
86_T179_I0.8690.53
595_P599_S0.8680.53
116_L127_I0.8650.52
82_N541_K0.8620.52
287_E590_N0.8620.52
401_V413_K0.8620.52
97_L369_E0.8610.52
192_K196_S0.8610.52
402_R409_D0.8600.52
556_L581_S0.8580.52
245_N351_K0.8580.52
234_A240_K0.8570.52
36_V129_K0.8550.51
510_P588_G0.8540.51
121_K223_F0.8520.51
403_K406_G0.8510.51
37_L144_L0.8450.51
38_V41_F0.8430.50
584_L587_A0.8390.50
244_K542_L0.8390.50
526_L536_K0.8360.50
234_A422_F0.8360.50
272_Y414_F0.8350.50
544_G602_F0.8340.50
525_L542_L0.8330.50
361_P467_F0.8320.50
47_K365_R0.8310.49
564_E574_R0.8310.49
309_L313_L0.8290.49
225_F361_P0.8280.49
232_G414_F0.8260.49
365_R369_E0.8260.49
396_R409_D0.8250.49
516_F519_G0.8230.49
205_I248_V0.8210.49
225_F341_F0.8210.49
510_P513_K0.8200.49
598_I601_Y0.8160.48
436_F439_K0.8140.48
138_E142_K0.8130.48
345_K349_A0.8090.48
36_V160_L0.8090.48
537_P558_E0.8070.47
97_L100_K0.8070.47
338_N358_D0.8060.47
434_K553_K0.8050.47
4_A249_C0.8030.47
420_A583_Y0.8000.47
178_K181_L0.8000.47
519_G605_G0.7990.47
324_I391_N0.7970.47
318_T323_E0.7970.47
137_K140_I0.7970.47
363_R422_F0.7960.46
87_S96_T0.7950.46
252_C563_L0.7940.46
272_Y598_I0.7940.46
271_F418_V0.7940.46
234_A363_R0.7930.46
270_R432_L0.7920.46
87_S90_T0.7890.46
164_K169_Y0.7870.46
293_I470_K0.7860.46
255_K275_N0.7850.46
313_L317_L0.7850.46
271_F374_V0.7850.46
19_K24_I0.7850.46
279_I330_E0.7800.45
82_N86_T0.7800.45
597_E605_G0.7790.45
89_T93_L0.7790.45
27_E88_K0.7770.45
40_N51_D0.7760.45
84_T170_L0.7760.45
354_L419_D0.7760.45
538_F563_L0.7720.44
164_K332_K0.7710.44
120_E124_L0.7710.44
139_K291_E0.7700.44
565_Q591_W0.7680.44
41_F198_A0.7680.44
17_E366_K0.7670.44
343_E353_L0.7670.44
521_L545_L0.7620.44
19_K30_K0.7610.44
249_C563_L0.7610.44
4_A9_G0.7610.44
547_M595_P0.7590.43
182_K428_D0.7590.43
32_K298_K0.7590.43
144_L339_F0.7580.43
406_G409_D0.7580.43
77_S99_K0.7580.43
211_E241_N0.7560.43
102_L309_L0.7550.43
267_L321_E0.7550.43
354_L415_L0.7540.43
278_L456_F0.7540.43
169_Y259_G0.7520.43
406_G410_K0.7510.43
90_T93_L0.7500.43
69_K163_L0.7490.43
174_E177_K0.7490.43
585_L588_G0.7480.42
432_L495_L0.7480.42
375_D390_F0.7480.42
543_N588_G0.7470.42
556_L559_V0.7460.42
398_F422_F0.7450.42
269_F276_Y0.7420.42
216_F599_S0.7410.42
400_P514_A0.7410.42
49_E392_F0.7410.42
23_D27_E0.7400.42
421_I467_F0.7400.42
495_L499_F0.7400.42
216_F253_A0.7390.42
372_E375_D0.7370.42
200_N434_K0.7360.41
561_N564_E0.7350.41
395_I421_I0.7350.41
344_R349_A0.7350.41
223_F260_K0.7340.41
546_G598_I0.7340.41
261_K335_L0.7330.41
436_F456_F0.7320.41
186_E189_F0.7310.41
543_N554_R0.7300.41
72_Y368_F0.7290.41
174_E292_E0.7280.41
186_E241_N0.7280.41
421_I464_L0.7280.41
542_L606_M0.7270.41
422_F467_F0.7260.41
390_F463_L0.7260.41
578_E584_L0.7230.40
94_E590_N0.7220.40
259_G553_K0.7210.40
554_R596_D0.7200.40
292_E295_D0.7190.40
280_P529_Q0.7160.40
546_G599_S0.7160.40
77_S86_T0.7150.40
228_T242_A0.7140.40
511_E593_L0.7130.40
2_I50_F0.7120.39
69_K138_E0.7120.39
216_F342_Y0.7120.39
137_K141_L0.7110.39
127_I311_K0.7110.39
149_K373_K0.7110.39
533_R540_K0.7110.39
495_L498_F0.7110.39
371_K422_F0.7100.39
546_G552_I0.7080.39
212_E251_D0.7080.39
228_T608_L0.7070.39
129_K133_E0.7070.39
97_L103_N0.7070.39
116_L120_E0.7050.39
419_D425_K0.7050.39
229_D363_R0.7050.39
581_S607_S0.7030.39
518_L584_L0.7030.39
469_E600_F0.7030.39
90_T96_T0.6990.38
466_L469_E0.6980.38
237_F414_F0.6970.38
204_S525_L0.6970.38
555_L562_K0.6970.38
290_L294_L0.6950.38
515_L589_D0.6940.38
63_D234_A0.6940.38
425_K518_L0.6940.38
10_E14_E0.6940.38
233_F502_Y0.6930.38
14_E174_E0.6920.38
138_E330_E0.6920.38
541_K606_M0.6910.38
182_K429_Y0.6910.38
174_E332_K0.6900.38
224_K228_T0.6890.38
111_K114_K0.6890.38
279_I460_K0.6880.38
214_Y228_T0.6880.38
146_E444_F0.6870.37
340_L585_L0.6870.37
541_K554_R0.6860.37
216_F272_Y0.6860.37
337_L422_F0.6840.37
78_A82_N0.6820.37
172_D465_L0.6810.37
524_K607_S0.6810.37
205_I238_D0.6810.37
545_L562_K0.6800.37
14_E23_D0.6790.37
277_Y458_V0.6780.37
206_C563_L0.6780.37
205_I256_L0.6760.37
602_F605_G0.6750.37
163_L426_P0.6740.36
253_A547_M0.6740.36
204_S347_Q0.6740.36
44_D131_L0.6730.36
350_F460_K0.6710.36
560_Q588_G0.6710.36
468_L473_L0.6710.36
11_Y248_V0.6710.36
604_L607_S0.6700.36
346_D421_I0.6700.36
522_T526_L0.6680.36
13_L24_I0.6680.36
144_L149_K0.6680.36
268_S277_Y0.6680.36
393_G471_L0.6670.36
486_E489_L0.6670.36
37_L173_I0.6660.36
229_D566_Y0.6660.36
244_K429_Y0.6660.36
427_I594_S0.6650.36
5_I377_L0.6640.36
549_E591_W0.6620.36
499_F608_L0.6620.36
138_E141_L0.6610.35
547_M555_L0.6590.35
148_L340_L0.6590.35
223_F512_K0.6590.35
294_L298_K0.6590.35
545_L565_Q0.6570.35
136_N141_L0.6570.35
205_I278_L0.6550.35
82_N97_L0.6510.35
589_D593_L0.6490.35
400_P403_K0.6490.35
526_L537_P0.6480.34
517_L521_L0.6480.34
526_L563_L0.6470.34
283_L534_G0.6470.34
77_S91_D0.6460.34
99_K103_N0.6450.34
8_I504_D0.6440.34
227_T230_K0.6430.34
518_L539_L0.6430.34
514_A518_L0.6400.34
517_L597_E0.6400.34
142_K147_K0.6390.34
545_L557_P0.6380.34
437_M551_D0.6380.34
30_K163_L0.6370.34
38_V54_E0.6370.34
2_I538_F0.6370.34
425_K473_L0.6340.33
279_I432_L0.6340.33
108_E114_K0.6330.33
98_S102_L0.6330.33
569_N577_E0.6330.33
17_E22_L0.6320.33
93_L97_L0.6320.33
246_F467_F0.6310.33
232_G360_L0.6300.33
209_K266_N0.6300.33
146_E359_V0.6290.33
123_F315_K0.6290.33
331_E504_D0.6290.33
256_L554_R0.6290.33
507_D567_D0.6290.33
69_K366_K0.6280.33
317_L428_D0.6280.33
226_Y423_T0.6250.33
2_I5_I0.6250.33
310_E364_L0.6250.33
229_D361_P0.6250.33
278_L360_L0.6240.33
560_Q574_R0.6230.33
204_S259_G0.6220.32
23_D72_Y0.6220.32
271_F544_G0.6210.32
85_P96_T0.6200.32
506_F588_G0.6180.32
22_L349_A0.6180.32
4_A206_C0.6180.32
127_I442_K0.6170.32
23_D28_N0.6170.32
23_D337_L0.6170.32
39_I286_L0.6160.32
406_G487_E0.6150.32
274_L600_F0.6140.32
223_F232_G0.6140.32
226_Y350_F0.6140.32
328_L370_A0.6140.32
151_I352_I0.6130.32
60_E66_K0.6130.32
81_P85_P0.6130.32
221_L257_E0.6130.32
541_K599_S0.6120.32
347_Q395_I0.6120.32
32_K347_Q0.6120.32
563_L576_L0.6120.32
454_L461_A0.6110.32
410_K414_F0.6110.32
111_K359_V0.6110.32
48_I160_L0.6110.32
480_M486_E0.6100.32
371_K390_F0.6100.32
170_L447_D0.6100.32
215_G253_A0.6090.31
39_I346_D0.6090.31
460_K514_A0.6080.31
281_K379_K0.6080.31
559_V585_L0.6070.31
176_Y321_E0.6070.31
346_D351_K0.6060.31
213_V540_K0.6060.31
72_Y82_N0.6050.31
68_K170_L0.6040.31
146_E178_K0.6040.31
276_Y352_I0.6040.31
260_K545_L0.6030.31
374_V467_F0.6030.31
253_A342_Y0.6030.31
323_E327_I0.6020.31
525_L557_P0.6020.31
115_E118_K0.6020.31
515_L546_G0.6020.31
353_L415_L0.6020.31
218_S235_S0.6010.31
215_G547_M0.6010.31
298_K407_D0.5990.31
48_I209_K0.5980.31
464_L576_L0.5980.31
224_K351_K0.5980.31
242_A246_F0.5980.31
556_L580_I0.5970.31
36_V171_G0.5970.31
497_E501_E0.5940.30
538_F566_Y0.5930.30
96_T102_L0.5930.30
519_G529_Q0.5930.30
62_F256_L0.5930.30
198_A213_V0.5920.30
14_E145_K0.5900.30
367_I567_D0.5900.30
518_L599_S0.5900.30
145_K148_L0.5880.30
342_Y349_A0.5880.30
361_P542_L0.5870.30
578_E583_Y0.5860.30
42_D48_I0.5860.30
552_I599_S0.5850.30
151_I159_V0.5850.30
125_K209_K0.5850.30
398_F467_F0.5850.30
163_L287_E0.5850.30
241_N421_I0.5840.30
12_L259_G0.5840.30
165_I372_E0.5840.30
480_M487_E0.5840.30
163_L198_A0.5830.30
526_L598_I0.5820.30
350_F415_L0.5800.29
127_I372_E0.5800.29
130_E468_L0.5800.29
133_E426_P0.5790.29
347_Q351_K0.5790.29
427_I537_P0.5790.29
168_K172_D0.5780.29
221_L342_Y0.5780.29
279_I369_E0.5770.29
234_A246_F0.5760.29
213_V367_I0.5750.29
551_D554_R0.5750.29
22_L25_L0.5750.29
20_D23_D0.5740.29
235_S536_K0.5730.29
77_S83_I0.5720.29
81_P84_T0.5720.29
249_C363_R0.5720.29
36_V244_K0.5710.29
260_K263_I0.5710.29
12_L59_L0.5700.29
330_E370_A0.5700.29
542_L599_S0.5700.29
42_D170_L0.5690.29
164_K167_G0.5690.29
127_I323_E0.5690.29
31_S46_G0.5690.29
234_A245_N0.5680.29
291_E346_D0.5680.29
2_I425_K0.5680.29
278_L452_F0.5680.29
448_E474_L0.5680.29
320_D323_E0.5670.28
288_E295_D0.5670.28
309_L312_E0.5670.28
8_I338_N0.5660.28
120_E126_K0.5660.28
493_E496_E0.5640.28
401_V411_Y0.5640.28
48_I474_L0.5630.28
139_K199_K0.5630.28
78_A93_L0.5630.28
369_E373_K0.5620.28
359_V447_D0.5620.28
102_L374_V0.5620.28
3_E63_D0.5620.28
231_P263_I0.5620.28
596_D600_F0.5610.28
593_L598_I0.5610.28
256_L513_K0.5600.28
152_K428_D0.5600.28
514_A591_W0.5590.28
269_F538_F0.5580.28
245_N338_N0.5580.28
522_T599_S0.5580.28
5_I60_E0.5580.28
338_N448_E0.5570.28
440_I530_Y0.5560.28
237_F247_P0.5560.28
182_K187_K0.5550.28
348_S594_S0.5540.28
95_K241_N0.5540.28
8_I202_V0.5540.28
543_N560_Q0.5530.28
166_D265_E0.5530.28
192_K351_K0.5530.28
277_Y587_A0.5530.28
74_K78_A0.5520.27
350_F459_L0.5520.27
332_K395_I0.5520.27
575_E580_I0.5510.27
306_L427_I0.5510.27
297_L302_K0.5500.27
558_E565_Q0.5500.27
528_I568_K0.5500.27
80_G83_I0.5490.27
185_L250_E0.5480.27
29_P62_F0.5480.27
502_Y505_F0.5470.27
24_I254_L0.5470.27
318_T322_E0.5470.27
278_L510_P0.5460.27
111_K118_K0.5460.27
451_D536_K0.5460.27
233_F459_L0.5450.27
227_T361_P0.5450.27
176_Y180_L0.5440.27
119_E311_K0.5430.27
23_D168_K0.5430.27
343_E349_A0.5420.27
477_G481_E0.5410.27
170_L177_K0.5410.27
440_I454_L0.5410.27
528_I539_L0.5410.27
238_D395_I0.5410.27
468_L474_L0.5410.27
577_E583_Y0.5400.27
556_L560_Q0.5400.27
421_I471_L0.5400.27
4_A534_G0.5400.27
23_D468_L0.5390.27
364_L391_N0.5390.27
54_E59_L0.5390.27
26_I469_E0.5390.27
123_F161_L0.5370.26
215_G271_F0.5370.26
562_K591_W0.5370.26
38_V60_E0.5360.26
465_L469_E0.5340.26
25_L28_N0.5340.26
599_S604_L0.5340.26
448_E453_Y0.5330.26
118_K127_I0.5330.26
483_G487_E0.5330.26
122_E126_K0.5320.26
561_N601_Y0.5320.26
169_Y279_I0.5320.26
542_L580_I0.5310.26
162_T201_G0.5310.26
146_E317_L0.5310.26
576_L579_A0.5310.26
161_L294_L0.5290.26
292_E323_E0.5280.26
400_P406_G0.5280.26
162_T333_D0.5280.26
127_I132_K0.5260.26
363_R399_F0.5250.26
46_G251_D0.5240.26
29_P257_E0.5240.26
226_Y246_F0.5230.26
436_F607_S0.5230.26
301_K304_K0.5220.25
184_L188_Y0.5220.25
21_P359_V0.5210.25
110_L559_V0.5210.25
278_L353_L0.5210.25
108_E112_K0.5200.25
434_K509_S0.5200.25
462_L498_F0.5190.25
127_I248_V0.5190.25
219_T223_F0.5190.25
499_F513_K0.5180.25
480_M483_G0.5180.25
390_F395_I0.5180.25
443_D479_K0.5170.25
520_V556_L0.5170.25
333_D367_I0.5170.25
144_L459_L0.5160.25
251_D372_E0.5160.25
223_F230_K0.5160.25
275_N348_S0.5150.25
493_E497_E0.5150.25
417_I461_A0.5150.25
443_D457_S0.5150.25
368_F371_K0.5140.25
195_K309_L0.5130.25
286_L290_L0.5130.25
352_I525_L0.5130.25
293_I372_E0.5120.25
405_K413_K0.5120.25
150_E310_E0.5120.25
91_D155_K0.5110.25
368_F600_F0.5110.25
92_E295_D0.5100.25
327_I372_E0.5100.25
359_V440_I0.5100.25
16_K21_P0.5100.25
34_K37_L0.5100.25
499_F502_Y0.5090.25
524_K571_Y0.5090.25
538_F562_K0.5090.25
83_I547_M0.5080.25
40_N49_E0.5070.25
569_N573_Y0.5070.25
49_E92_E0.5070.25
325_L339_F0.5060.24
560_Q578_E0.5060.24
337_L502_Y0.5060.24
232_G560_Q0.5050.24
273_G401_V0.5050.24
277_Y348_S0.5030.24
346_D406_G0.5030.24
179_I183_K0.5020.24
198_A594_S0.5020.24
593_L601_Y0.5020.24
352_I380_E0.5010.24
88_K160_L0.5010.24
396_R401_V0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ds5A 2 0.0722 41.9 0.972 Contact Map
2zjrU 1 0.0969 38.5 0.972 Contact Map
4tp8N 1 0.1576 22.4 0.975 Contact Map
4rb61 1 0.1379 22.1 0.975 Contact Map
4tp9X 1 0.1133 19.4 0.976 Contact Map
3bbnN 1 0.1626 15.6 0.977 Contact Map
4lh9A 4 0.0657 15.6 0.977 Contact Map
1ovxA 2 0.0624 7.2 0.98 Contact Map
4rb5N 1 0.0985 6.9 0.98 Contact Map
2jz6A 1 0.1166 5.4 0.981 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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