Gly_reductase - PFAM28P - GREMLIN Contacts

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Gly_reductase - Glycine/sarcosine/betaine reductase component B subunits

PFAM:	PF09338	Sequences: MRLELGNIPIKDVQFGDKTKVEDGVLTVNKEELLALVLEDERIASVDLEIARPGESVRIIPVKDVIEPRVKVEGPGGVFPGVLGPVETVGEGRTHVLKGAAVVTTGKIVGFQEGIIDMSGPGAEYTPFSKTNNLVLVAEPVEGLEQHEYEKAVRLAGLKAAVYLAEAARDLEPDEVEVYELPPLLERAAEYPGLPRVAYVYQLQSQGLLHDTYVYGVDAKGILPTLLHPNEVLDGAIVSGNCVSACDKNTTYHHQNNPVILELYRRHGKDLNFVGVILTNENVTLADKERSSNMAAKLAEMLGADGAIITEEGGGNPDTDLMMNCKKLEKAGIKTVLITDEYAGRDGASQSLADADPEADAVVSTGNANEVIELPPMDRVIGGLEAADVIAGGFAGSLREDGSIEVELQAITGATNELGFSKLTAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	426 (423)
Sequences:	1624 (913)
Seq/√Len:	44.4
META:	0.789

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
266_R	270_D	5.873	1.00
198_A	304_A	4.980	1.00
277_I	299_A	4.397	1.00
259_V	338_I	4.361	1.00
29_N	32_E	4.073	1.00
19_T	167_A	3.718	1.00
300_E	331_A	3.655	1.00
103_V	116_I	3.637	1.00
48_L	134_L	3.609	1.00
56_S	378_D	3.571	1.00
13_V	134_L	3.444	1.00
100_A	134_L	3.285	1.00
10_I	21_V	3.274	1.00
166_E	169_R	3.220	1.00
16_G	27_T	3.204	1.00
181_L	228_H	2.987	1.00
12_D	52_R	2.979	1.00
330_K	358_E	2.966	1.00
37_V	160_A	2.903	1.00
31_E	35_A	2.867	1.00
33_L	160_A	2.866	1.00
198_A	274_V	2.750	1.00
7_N	98_K	2.745	1.00
406_V	410_A	2.684	1.00
121_P	124_E	2.680	1.00
15_F	30_K	2.680	1.00
11_K	24_G	2.674	1.00
307_A	328_L	2.647	1.00
232_V	260_I	2.622	1.00
230_N	264_Y	2.617	1.00
28_V	134_L	2.601	1.00
9_P	174_D	2.562	1.00
250_T	253_H	2.534	1.00
177_E	261_L	2.529	1.00
77_G	84_G	2.519	1.00
2_R	178_V	2.469	1.00
119_S	377_M	2.446	1.00
4_E	93_R	2.423	1.00
82_V	238_V	2.373	1.00
101_A	131_T	2.261	1.00
177_E	265_R	2.224	1.00
399_R	405_E	2.215	1.00
15_F	50_I	2.204	1.00
34_L	38_L	2.197	1.00
93_R	176_V	2.160	1.00
198_A	307_A	2.153	1.00
52_R	132_N	2.143	1.00
50_I	134_L	2.111	1.00
121_P	375_P	2.102	1.00
65_V	103_V	2.057	0.99
30_K	47_D	2.042	0.99
49_E	137_V	1.975	0.99
322_M	359_A	1.951	0.99
4_E	178_V	1.942	0.99
103_V	133_N	1.931	0.99
49_E	379_R	1.920	0.99
326_K	358_E	1.911	0.99
73_E	93_R	1.909	0.99
196_R	303_G	1.895	0.99
181_L	230_N	1.887	0.99
6_G	95_H	1.883	0.99
259_V	310_T	1.847	0.99
214_V	219_A	1.837	0.99
9_P	98_K	1.815	0.99
51_A	57_V	1.815	0.99
12_D	25_V	1.805	0.98
182_P	190_E	1.801	0.98
228_H	264_Y	1.793	0.98
8_I	168_A	1.789	0.98
274_V	304_A	1.787	0.98
32_E	163_Y	1.759	0.98
373_E	405_E	1.740	0.98
227_L	278_L	1.721	0.98
200_V	295_A	1.721	0.98
13_V	100_A	1.718	0.98
71_K	94_T	1.691	0.98
160_A	163_Y	1.664	0.97
179_Y	261_L	1.663	0.97
14_Q	25_V	1.653	0.97
200_V	277_I	1.635	0.97
66_I	157_G	1.632	0.97
45_S	139_E	1.628	0.97
79_F	255_Q	1.622	0.97
51_A	59_I	1.609	0.97
215_Y	231_E	1.589	0.96
20_K	27_T	1.587	0.96
31_E	34_L	1.578	0.96
72_V	95_H	1.572	0.96
35_A	39_E	1.563	0.96
56_S	377_M	1.554	0.96
296_A	327_K	1.551	0.96
8_I	21_V	1.533	0.96
6_G	173_P	1.508	0.95
373_E	399_R	1.504	0.95
42_R	152_A	1.503	0.95
33_L	48_L	1.494	0.95
326_K	356_D	1.493	0.95
296_A	331_A	1.490	0.95
67_E	98_K	1.489	0.95
36_L	160_A	1.489	0.95
214_V	227_L	1.486	0.95
65_V	116_I	1.483	0.95
95_H	168_A	1.457	0.94
201_Y	260_I	1.453	0.94
327_K	330_K	1.431	0.94
162_V	166_E	1.411	0.93
51_A	381_I	1.405	0.93
201_Y	232_V	1.400	0.93
134_L	164_L	1.391	0.93
52_R	55_E	1.391	0.93
141_V	144_L	1.391	0.93
307_A	333_I	1.386	0.93
2_R	180_E	1.382	0.93
62_V	116_I	1.380	0.92
94_T	234_D	1.376	0.92
96_V	100_A	1.369	0.92
367_N	370_E	1.356	0.92
42_R	151_K	1.353	0.92
200_V	299_A	1.339	0.91
200_V	328_L	1.339	0.91
294_M	297_K	1.336	0.91
388_D	396_G	1.328	0.91
32_E	36_L	1.326	0.91
44_A	142_E	1.320	0.91
326_K	330_K	1.316	0.91
196_R	274_V	1.315	0.91
36_L	46_V	1.314	0.90
40_D	156_A	1.310	0.90
102_V	164_L	1.307	0.90
38_L	46_V	1.304	0.90
30_K	34_L	1.304	0.90
100_A	132_N	1.299	0.90
185_L	188_A	1.296	0.90
14_Q	27_T	1.291	0.90
34_L	46_V	1.279	0.89
19_T	32_E	1.271	0.89
328_L	331_A	1.260	0.89
11_K	23_D	1.257	0.88
13_V	132_N	1.252	0.88
277_I	304_A	1.244	0.88
8_I	95_H	1.244	0.88
34_L	47_D	1.235	0.87
275_G	304_A	1.235	0.87
62_V	103_V	1.220	0.87
343_A	367_N	1.220	0.87
6_G	93_R	1.212	0.86
66_I	161_A	1.211	0.86
263_L	271_L	1.178	0.85
123_A	129_S	1.169	0.84
329_E	335_T	1.157	0.84
334_K	360_D	1.150	0.83
233_L	261_L	1.150	0.83
28_V	37_V	1.136	0.83
262_E	265_R	1.136	0.83
11_K	25_V	1.132	0.82
71_K	234_D	1.126	0.82
56_S	119_S	1.123	0.82
197_V	306_G	1.108	0.81
219_A	222_I	1.107	0.81
203_L	237_I	1.107	0.81
214_V	278_L	1.107	0.81
397_S	404_I	1.105	0.81
292_S	327_K	1.102	0.81
91_E	300_E	1.089	0.80
36_L	39_E	1.086	0.80
7_N	96_V	1.082	0.79
8_I	171_L	1.075	0.79
48_L	136_L	1.074	0.79
28_V	50_I	1.067	0.79
341_E	364_S	1.064	0.78
73_E	76_G	1.061	0.78
10_I	14_Q	1.060	0.78
90_G	234_D	1.053	0.78
88_T	297_K	1.051	0.77
288_K	316_N	1.040	0.77
200_V	307_A	1.036	0.76
83_L	162_V	1.032	0.76
207_G	211_D	1.027	0.76
69_R	256_N	1.023	0.76
79_F	161_A	1.016	0.75
165_A	168_A	1.009	0.75
50_I	100_A	1.008	0.74
408_L	415_T	1.000	0.74
55_E	136_L	1.000	0.74
36_L	159_K	0.998	0.74
355_A	359_A	0.996	0.74
388_D	394_F	0.993	0.73
227_L	294_M	0.993	0.73
168_A	171_L	0.987	0.73
254_H	257_N	0.981	0.72
199_Y	310_T	0.979	0.72
44_A	139_E	0.977	0.72
296_A	328_L	0.976	0.72
17_D	29_N	0.973	0.72
376_P	403_S	0.962	0.71
244_S	314_G	0.961	0.71
225_T	294_M	0.954	0.70
180_E	264_Y	0.950	0.70
10_I	168_A	0.936	0.69
79_F	83_L	0.925	0.68
47_D	139_E	0.922	0.68
322_M	355_A	0.921	0.68
266_R	271_L	0.919	0.67
90_G	94_T	0.918	0.67
22_E	27_T	0.915	0.67
24_G	174_D	0.913	0.67
309_I	325_C	0.912	0.67
55_E	379_R	0.911	0.67
43_I	152_A	0.910	0.67
258_P	418_L	0.908	0.66
34_L	45_S	0.908	0.66
4_E	176_V	0.907	0.66
179_Y	264_Y	0.907	0.66
44_A	141_V	0.904	0.66
14_Q	52_R	0.903	0.66
57_V	119_S	0.901	0.66
198_A	302_L	0.900	0.66
288_K	341_E	0.900	0.66
52_R	57_V	0.898	0.66
72_V	76_G	0.887	0.65
241_N	312_E	0.885	0.64
73_E	145_E	0.885	0.64
104_T	157_G	0.884	0.64
237_I	278_L	0.882	0.64
37_V	159_K	0.881	0.64
68_P	102_V	0.878	0.64
154_R	240_G	0.877	0.64
17_D	24_G	0.874	0.63
206_Q	312_E	0.873	0.63
36_L	142_E	0.867	0.63
201_Y	254_H	0.866	0.63
18_K	22_E	0.865	0.63
215_Y	236_A	0.861	0.62
206_Q	316_N	0.860	0.62
19_T	163_Y	0.858	0.62
196_R	272_N	0.858	0.62
260_I	273_F	0.855	0.62
15_F	32_E	0.852	0.61
32_E	164_L	0.849	0.61
106_G	109_V	0.849	0.61
344_G	347_G	0.847	0.61
150_E	316_N	0.844	0.61
183_P	303_G	0.843	0.61
341_E	347_G	0.842	0.61
39_E	159_K	0.841	0.60
232_V	276_V	0.840	0.60
299_A	304_A	0.838	0.60
207_G	210_H	0.833	0.60
187_R	196_R	0.833	0.60
181_L	264_Y	0.829	0.59
292_S	324_N	0.828	0.59
37_V	136_L	0.825	0.59
409_Q	415_T	0.824	0.59
383_G	386_A	0.820	0.58
17_D	31_E	0.817	0.58
233_L	257_N	0.816	0.58
206_Q	313_G	0.814	0.58
101_A	133_N	0.814	0.58
280_N	283_V	0.811	0.58
95_H	173_P	0.809	0.57
314_G	368_A	0.808	0.57
93_R	172_E	0.807	0.57
6_G	72_V	0.805	0.57
325_C	359_A	0.804	0.57
253_H	416_N	0.802	0.57
164_L	423_L	0.798	0.56
232_V	237_I	0.798	0.56
11_K	17_D	0.796	0.56
394_F	406_V	0.795	0.56
267_H	272_N	0.795	0.56
78_V	165_A	0.793	0.56
161_A	255_Q	0.793	0.56
18_K	32_E	0.791	0.56
67_E	256_N	0.790	0.56
417_E	420_F	0.790	0.56
64_D	71_K	0.789	0.56
78_V	89_V	0.789	0.56
206_Q	248_K	0.787	0.55
172_E	176_V	0.785	0.55
226_L	302_L	0.785	0.55
199_Y	257_N	0.784	0.55
293_N	327_K	0.782	0.55
194_L	267_H	0.782	0.55
248_K	312_E	0.782	0.55
9_P	175_E	0.781	0.55
140_P	149_Y	0.781	0.55
72_V	173_P	0.779	0.55
325_C	337_L	0.778	0.54
204_Q	281_E	0.777	0.54
206_Q	254_H	0.776	0.54
297_K	301_M	0.772	0.54
28_V	33_L	0.771	0.54
61_P	383_G	0.767	0.53
136_L	156_A	0.764	0.53
119_S	375_P	0.756	0.52
316_N	344_G	0.756	0.52
97_L	168_A	0.756	0.52
21_V	27_T	0.754	0.52
7_N	177_E	0.753	0.52
11_K	18_K	0.753	0.52
15_F	48_L	0.752	0.52
356_D	359_A	0.752	0.52
13_V	28_V	0.751	0.52
100_A	131_T	0.750	0.52
135_V	381_I	0.749	0.52
399_R	403_S	0.747	0.51
224_P	294_M	0.747	0.51
262_E	266_R	0.747	0.51
345_R	394_F	0.747	0.51
48_L	100_A	0.747	0.51
75_P	91_E	0.745	0.51
182_P	187_R	0.740	0.51
311_E	416_N	0.739	0.51
50_I	132_N	0.738	0.51
233_L	264_Y	0.736	0.50
231_E	236_A	0.735	0.50
317_P	349_S	0.732	0.50
43_I	140_P	0.730	0.50
71_K	90_G	0.729	0.50
289_E	306_G	0.729	0.50
122_G	129_S	0.727	0.50
24_G	27_T	0.726	0.49
21_V	167_A	0.726	0.49
232_V	278_L	0.726	0.49
38_L	45_S	0.723	0.49
208_L	211_D	0.721	0.49
46_V	156_A	0.721	0.49
316_N	325_C	0.717	0.49
384_L	387_A	0.716	0.49
202_Q	309_I	0.716	0.49
7_N	175_E	0.714	0.48
14_Q	28_V	0.714	0.48
343_A	370_E	0.714	0.48
22_E	269_K	0.712	0.48
199_Y	259_V	0.710	0.48
413_G	416_N	0.708	0.48
292_S	323_M	0.707	0.48
214_V	222_I	0.706	0.48
227_L	232_V	0.705	0.47
63_K	317_P	0.703	0.47
192_P	272_N	0.702	0.47
191_Y	196_R	0.702	0.47
105_T	137_V	0.702	0.47
48_L	160_A	0.701	0.47
21_V	24_G	0.701	0.47
63_K	150_E	0.701	0.47
60_I	387_A	0.700	0.47
155_L	159_K	0.698	0.47
51_A	55_E	0.697	0.47
319_T	355_A	0.696	0.47
51_A	135_V	0.695	0.46
311_E	337_L	0.692	0.46
116_I	133_N	0.692	0.46
393_G	410_A	0.691	0.46
95_H	165_A	0.689	0.46
340_D	368_A	0.688	0.46
344_G	369_N	0.687	0.46
181_L	187_R	0.687	0.46
5_L	69_R	0.685	0.46
78_V	162_V	0.684	0.45
15_F	18_K	0.683	0.45
242_C	312_E	0.681	0.45
390_I	410_A	0.681	0.45
397_S	405_E	0.679	0.45
25_V	31_E	0.678	0.45
19_T	165_A	0.678	0.45
262_E	270_D	0.678	0.45
89_V	94_T	0.676	0.45
6_G	171_L	0.675	0.45
393_G	396_G	0.673	0.44
322_M	356_D	0.673	0.44
204_Q	248_K	0.671	0.44
37_V	163_Y	0.670	0.44
14_Q	20_K	0.669	0.44
185_L	189_A	0.668	0.44
180_E	183_P	0.664	0.44
12_D	55_E	0.663	0.43
204_Q	311_E	0.662	0.43
13_V	48_L	0.662	0.43
322_M	325_C	0.659	0.43
60_I	383_G	0.659	0.43
253_H	421_S	0.656	0.43
60_I	198_A	0.656	0.43
37_V	40_D	0.656	0.43
408_L	423_L	0.656	0.43
95_H	171_L	0.655	0.43
299_A	333_I	0.653	0.42
186_E	189_A	0.653	0.42
347_G	351_S	0.650	0.42
49_E	135_V	0.648	0.42
155_L	238_V	0.648	0.42
122_G	372_I	0.648	0.42
289_E	326_K	0.647	0.42
78_V	255_Q	0.645	0.42
183_P	190_E	0.640	0.41
57_V	379_R	0.639	0.41
207_G	254_H	0.638	0.41
247_D	314_G	0.637	0.41
247_D	340_D	0.636	0.41
304_A	333_I	0.636	0.41
128_F	250_T	0.636	0.41
342_Y	364_S	0.635	0.41
30_K	38_L	0.635	0.41
96_V	99_G	0.634	0.41
254_H	312_E	0.633	0.41
194_L	268_G	0.633	0.41
112_Q	209_L	0.633	0.41
257_N	289_E	0.633	0.41
94_T	231_E	0.633	0.41
318_D	353_A	0.633	0.41
381_I	411_I	0.631	0.40
179_Y	265_R	0.631	0.40
365_T	417_E	0.630	0.40
124_E	130_K	0.630	0.40
369_N	409_Q	0.630	0.40
207_G	212_T	0.628	0.40
194_L	273_F	0.628	0.40
396_G	406_V	0.627	0.40
72_V	93_R	0.626	0.40
38_L	43_I	0.625	0.40
411_I	414_A	0.625	0.40
388_D	395_A	0.623	0.40
70_V	169_R	0.623	0.40
204_Q	280_N	0.621	0.39
400_E	403_S	0.619	0.39
198_A	275_G	0.618	0.39
122_G	374_L	0.618	0.39
225_T	290_R	0.617	0.39
170_D	305_D	0.617	0.39
99_G	132_N	0.616	0.39
101_A	255_Q	0.615	0.39
19_T	29_N	0.615	0.39
138_A	160_A	0.615	0.39
282_N	291_S	0.614	0.39
340_D	349_S	0.612	0.39
217_V	222_I	0.612	0.39
206_Q	285_L	0.611	0.39
261_L	265_R	0.611	0.39
10_I	27_T	0.609	0.38
12_D	132_N	0.609	0.38
215_Y	234_D	0.609	0.38
6_G	10_I	0.608	0.38
376_P	380_V	0.607	0.38
251_T	255_Q	0.606	0.38
191_Y	272_N	0.605	0.38
384_L	388_D	0.605	0.38
311_E	318_D	0.605	0.38
138_A	153_V	0.605	0.38
115_I	374_L	0.605	0.38
238_V	251_T	0.603	0.38
226_L	274_V	0.602	0.38
182_P	185_L	0.601	0.38
2_R	134_L	0.600	0.38
313_G	317_P	0.600	0.38
128_F	253_H	0.599	0.37
296_A	324_N	0.598	0.37
198_A	299_A	0.598	0.37
248_K	316_N	0.596	0.37
153_V	156_A	0.596	0.37
63_K	213_Y	0.596	0.37
342_Y	368_A	0.594	0.37
204_Q	282_N	0.594	0.37
413_G	418_L	0.593	0.37
198_A	277_I	0.592	0.37
158_L	238_V	0.592	0.37
279_T	291_S	0.592	0.37
52_R	334_K	0.591	0.37
161_A	251_T	0.591	0.37
122_G	136_L	0.591	0.37
10_I	24_G	0.589	0.37
233_L	307_A	0.589	0.37
49_E	57_V	0.588	0.36
148_E	152_A	0.588	0.36
226_L	301_M	0.588	0.36
197_V	385_E	0.586	0.36
401_D	407_E	0.584	0.36
202_Q	317_P	0.580	0.36
84_G	135_V	0.579	0.36
209_L	244_S	0.579	0.36
47_D	137_V	0.578	0.36
112_Q	313_G	0.577	0.36
42_R	295_A	0.575	0.35
345_R	349_S	0.575	0.35
36_L	163_Y	0.575	0.35
85_P	289_E	0.575	0.35
149_Y	153_V	0.573	0.35
409_Q	418_L	0.573	0.35
105_T	149_Y	0.573	0.35
200_V	279_T	0.571	0.35
202_Q	290_R	0.570	0.35
39_E	46_V	0.569	0.35
281_E	311_E	0.568	0.35
208_L	212_T	0.568	0.35
209_L	212_T	0.567	0.35
107_K	110_G	0.567	0.35
323_M	326_K	0.567	0.35
248_K	313_G	0.566	0.35
205_S	282_N	0.566	0.35
130_K	269_K	0.565	0.34
317_P	340_D	0.564	0.34
281_E	318_D	0.564	0.34
145_E	148_E	0.563	0.34
106_G	111_F	0.563	0.34
359_A	362_V	0.562	0.34
248_K	367_N	0.562	0.34
116_I	239_S	0.562	0.34
127_P	133_N	0.561	0.34
350_Q	368_A	0.560	0.34
175_E	178_V	0.560	0.34
314_G	409_Q	0.560	0.34
245_A	368_A	0.559	0.34
206_Q	344_G	0.559	0.34
388_D	404_I	0.559	0.34
404_I	412_T	0.558	0.34
237_I	249_N	0.558	0.34
362_V	417_E	0.558	0.34
6_G	70_V	0.557	0.34
187_R	364_S	0.556	0.34
190_E	272_N	0.555	0.34
225_T	298_L	0.555	0.34
394_F	403_S	0.554	0.33
395_A	421_S	0.554	0.33
78_V	233_L	0.554	0.33
266_R	308_I	0.551	0.33
368_A	391_A	0.551	0.33
414_A	417_E	0.550	0.33
199_Y	325_C	0.550	0.33
282_N	319_T	0.550	0.33
92_G	234_D	0.550	0.33
289_E	327_K	0.549	0.33
391_A	409_Q	0.548	0.33
187_R	190_E	0.548	0.33
377_M	397_S	0.547	0.33
18_K	29_N	0.547	0.33
416_N	421_S	0.546	0.33
314_G	342_Y	0.546	0.33
183_P	187_R	0.545	0.33
237_I	386_A	0.545	0.33
299_A	309_I	0.545	0.33
51_A	56_S	0.545	0.33
387_A	391_A	0.544	0.33
62_V	65_V	0.543	0.33
203_L	257_N	0.542	0.32
257_N	319_T	0.542	0.32
113_E	213_Y	0.541	0.32
180_E	184_L	0.540	0.32
233_L	255_Q	0.539	0.32
21_V	174_D	0.538	0.32
283_V	318_D	0.538	0.32
250_T	412_T	0.538	0.32
225_T	297_K	0.537	0.32
5_L	94_T	0.537	0.32
204_Q	344_G	0.537	0.32
350_Q	353_A	0.536	0.32
104_T	110_G	0.536	0.32
119_S	378_D	0.536	0.32
20_K	23_D	0.536	0.32
202_Q	318_D	0.535	0.32
29_N	163_Y	0.535	0.32
34_L	48_L	0.534	0.32
9_P	21_V	0.533	0.32
28_V	67_E	0.532	0.32
224_P	315_G	0.531	0.32
150_E	241_N	0.531	0.32
271_L	338_I	0.531	0.32
7_N	167_A	0.530	0.31
14_Q	46_V	0.530	0.31
202_Q	205_S	0.530	0.31
9_P	170_D	0.530	0.31
176_V	307_A	0.530	0.31
207_G	354_D	0.530	0.31
393_G	397_S	0.530	0.31
243_V	312_E	0.529	0.31
239_S	248_K	0.529	0.31
197_V	307_A	0.529	0.31
45_S	193_G	0.528	0.31
7_N	179_Y	0.528	0.31
104_T	107_K	0.527	0.31
6_G	176_V	0.527	0.31
50_I	181_L	0.526	0.31
12_D	27_T	0.526	0.31
77_G	162_V	0.525	0.31
54_G	58_R	0.525	0.31
103_V	131_T	0.525	0.31
390_I	394_F	0.525	0.31
153_V	168_A	0.525	0.31
92_G	231_E	0.522	0.31
94_T	225_T	0.522	0.31
153_V	160_A	0.521	0.31
306_G	357_P	0.520	0.31
253_H	306_G	0.519	0.31
106_G	392_G	0.518	0.30
2_R	17_D	0.518	0.30
37_V	46_V	0.518	0.30
243_V	247_D	0.517	0.30
218_D	221_G	0.517	0.30
82_V	201_Y	0.517	0.30
387_A	394_F	0.517	0.30
200_V	309_I	0.516	0.30
68_P	255_Q	0.516	0.30
388_D	398_L	0.516	0.30
199_Y	273_F	0.516	0.30
224_P	264_Y	0.515	0.30
55_E	58_R	0.515	0.30
357_P	360_D	0.515	0.30
187_R	274_V	0.513	0.30
109_V	242_C	0.512	0.30
223_L	294_M	0.512	0.30
299_A	328_L	0.511	0.30
205_S	219_A	0.511	0.30
409_Q	412_T	0.511	0.30
37_V	43_I	0.511	0.30
33_L	134_L	0.510	0.30
37_V	45_S	0.510	0.30
70_V	95_H	0.510	0.30
196_R	271_L	0.509	0.30
239_S	243_V	0.509	0.30
98_K	175_E	0.508	0.30
223_L	277_I	0.508	0.30
340_D	343_A	0.508	0.30
300_E	333_I	0.507	0.30
85_P	303_G	0.506	0.30
37_V	48_L	0.506	0.30
243_V	342_Y	0.505	0.29
386_A	389_V	0.504	0.29
21_V	50_I	0.504	0.29
91_E	296_A	0.503	0.29
101_A	252_Y	0.503	0.29
254_H	318_D	0.503	0.29
129_S	177_E	0.502	0.29
280_N	317_P	0.502	0.29
189_A	192_P	0.501	0.29
63_K	242_C	0.501	0.29
187_R	228_H	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ra9B	1	0.2864	55.6	0.975	Contact Map
2hy5A	2	0.2136	17.2	0.981	Contact Map
1tr8A	4	0.1714	15.6	0.981	Contact Map
3x2fA	4	0.3967	14.5	0.982	Contact Map
3ofhA	2	0.1221	14.5	0.982	Contact Map
2cfuA	2	0.1573	14.3	0.982	Contact Map
3u12A	2	0.1197	14	0.982	Contact Map
3offA	1	0.1221	13.3	0.982	Contact Map
2himA	4	0.6315	10.5	0.983	Contact Map
3f02C	1	0.0869	10.5	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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