GREMLIN Database
CbbQ_C - CbbQ/NirQ/NorQ C-terminal
PFAM: PF08406 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 85 (84)
Sequences: 8905 (4754)
Seq/√Len: 518.7
META: 0.918

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
61_R79_D3.4711.00
2_A17_A2.8811.00
6_A13_E2.3931.00
12_D15_T2.2431.00
11_V15_T2.0291.00
13_E17_A2.0121.00
2_A13_E2.0021.00
50_I56_P1.9411.00
2_A6_A1.9301.00
57_R83_D1.8681.00
26_I38_A1.8111.00
11_V16_A1.7581.00
21_K25_K1.7421.00
9_S47_A1.7211.00
19_L43_L1.6371.00
22_L82_V1.5981.00
23_A43_L1.5971.00
25_K28_N1.4781.00
19_L46_A1.4671.00
3_E6_A1.4061.00
6_A16_A1.3981.00
3_E7_H1.3861.00
46_A63_A1.3691.00
26_I37_G1.3461.00
3_E13_E1.3321.00
55_P58_E1.3011.00
20_V24_E1.2641.00
80_E83_D1.2411.00
65_V82_V1.2181.00
14_E18_K1.2111.00
46_A60_C1.1961.00
26_I78_L1.1921.00
5_V43_L1.1851.00
66_E75_R1.1821.00
79_D83_D1.1581.00
58_E62_A1.1401.00
61_R66_E1.1331.00
15_T18_K1.1031.00
28_N32_H1.1001.00
74_V77_A1.0911.00
66_E79_D1.0791.00
17_A21_K1.0661.00
2_A20_V1.0591.00
21_K24_E1.0481.00
5_V9_S1.0281.00
22_L81_L1.0001.00
80_E84_A0.9981.00
76_A80_E0.9981.00
15_T50_I0.9781.00
16_A20_V0.9721.00
14_E17_A0.9651.00
42_L45_Y0.9241.00
48_R51_A0.9221.00
5_V20_V0.9141.00
10_G51_A0.9071.00
22_L26_I0.8921.00
65_V79_D0.8681.00
58_E61_R0.8601.00
65_V75_R0.8481.00
18_K21_K0.8461.00
43_L64_I0.8451.00
46_A64_I0.8381.00
30_K37_G0.8381.00
40_T44_V0.8361.00
61_R83_D0.8241.00
69_T75_R0.8171.00
38_A42_L0.8161.00
19_L23_A0.7951.00
49_L63_A0.7931.00
79_D82_V0.7861.00
6_A9_S0.7721.00
32_H45_Y0.7671.00
75_R79_D0.7631.00
48_R52_A0.7521.00
1_E27_R0.7251.00
8_E44_V0.7221.00
29_L32_H0.7201.00
4_I8_E0.7161.00
21_K28_N0.7151.00
35_E45_Y0.7111.00
65_V78_L0.7091.00
50_I53_G0.6991.00
19_L50_I0.6951.00
45_Y48_R0.6891.00
9_S51_A0.6881.00
72_P75_R0.6791.00
36_E39_S0.6761.00
27_R40_T0.6761.00
60_C82_V0.6731.00
26_I68_L0.6671.00
76_A79_D0.6611.00
36_E42_L0.6601.00
73_D76_A0.6591.00
11_V47_A0.6591.00
62_A66_E0.6551.00
25_K80_E0.6461.00
76_A83_D0.6411.00
38_A64_I0.6341.00
26_I81_L0.6151.00
64_I67_P0.6051.00
63_A67_P0.6001.00
31_G35_E0.5980.99
35_E74_V0.5970.99
47_A50_I0.5930.99
25_K81_L0.5880.99
5_V47_A0.5860.99
59_A70_D0.5830.99
12_D18_K0.5800.99
50_I59_A0.5780.99
60_C64_I0.5730.99
15_T56_P0.5710.99
24_E28_N0.5680.99
9_S48_R0.5640.99
33_G74_V0.5630.99
57_R61_R0.5590.99
72_P76_A0.5570.99
74_V78_L0.5500.99
32_H81_L0.5450.99
5_V8_E0.5290.99
25_K32_H0.5220.99
9_S44_V0.5200.99
56_P60_C0.5150.98
36_E69_T0.5130.98
18_K84_A0.5050.98
26_I34_L0.5010.98
28_N31_G0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4akgA 2 0.9765 63.4 0.811 Contact Map
3vkgA 2 0.9765 54.9 0.82 Contact Map
2r44A 1 1 42.6 0.833 Contact Map
4r7yA 3 0.8353 31.8 0.845 Contact Map
1tr2A 1 0.9529 23.8 0.854 Contact Map
3nbxX 1 0.9412 22.6 0.855 Contact Map
1g8pA 1 0.8 20.8 0.857 Contact Map
3ja87 1 0.8235 19.8 0.859 Contact Map
3vf0A 1 0.8588 17.6 0.862 Contact Map
3ja83 1 0.8706 16.9 0.864 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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