DUF1688 - PFAM28P - GREMLIN Contacts

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DUF1688 - Protein of unknown function (DUF1688)

PFAM:	PF07958	Sequences: YLLSAAAVRERAHRVLALALAGRLPHFRVDLDRLDAAADYVAAVTRRRYGPDLDSIPFHSRWRHFEAGGVDRWAELAARLASWLDPAERARALIDLAIVSVLLDAGAGPAWRYREPETGQTFGRSEGLAVASLRMFAAGAFSSDPADPLRVDAAALARLTAADLARGFQVSPDNPLVGLEGRAALLRRLGEALAARPDVFGREPRPGGLFDYLAARASTSSGGRLPAPAILSALLDGLGPIWPASRLTLGGVPLGDCWRHPALGGDDATDGLVPFHKLSQWLTYSLIEPLEWLAGITVTGLDGLTGLPEYRNGGLFVDTGVLVLRDPADARGLEAYGEARAHEVGSELVVEWRALTVALLDRLAPLVRARLGLDAEELPLAKVLEGGTWAAGREIAAELRPPDGGPPIKIISDGTVF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	417 (399)
Sequences:	1587 (1074)
Seq/√Len:	53.8
META:	0.686

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
234_L	283_T	3.785	1.00
324_L	330_A	3.507	1.00
19_A	24_L	3.506	1.00
317_V	408_I	3.492	1.00
374_D	377_E	3.310	1.00
306_G	360_L	3.260	1.00
47_R	394_E	3.084	1.00
161_A	180_E	3.073	1.00
58_F	291_E	2.990	1.00
324_L	348_L	2.978	1.00
39_D	370_R	2.965	1.00
37_A	319_T	2.818	1.00
95_D	206_P	2.810	1.00
261_P	347_E	2.747	1.00
147_D	150_R	2.715	1.00
135_M	167_G	2.668	1.00
30_D	323_V	2.654	1.00
91_R	211_D	2.632	1.00
35_D	366_L	2.610	1.00
4_S	7_A	2.607	1.00
112_R	121_T	2.600	1.00
183_A	187_R	2.528	1.00
342_H	348_L	2.488	1.00
329_D	348_L	2.466	1.00
385_E	390_A	2.404	1.00
99_V	151_V	2.387	1.00
42_A	367_V	2.373	1.00
257_C	272_L	2.321	1.00
316_F	321_V	2.289	1.00
16_L	358_A	2.271	1.00
199_V	237_G	2.259	1.00
287_I	301_L	2.244	1.00
38_A	366_L	2.205	1.00
161_A	183_A	2.203	1.00
40_Y	398_E	2.197	1.00
234_L	279_S	2.173	1.00
93_L	292_W	2.140	1.00
373_L	377_E	2.106	1.00
140_A	167_G	2.096	1.00
40_Y	319_T	2.075	1.00
5_A	8_V	2.026	1.00
342_H	346_S	1.978	1.00
135_M	141_F	1.955	1.00
300_G	303_G	1.955	1.00
12_A	273_V	1.949	1.00
275_F	308_P	1.904	0.99
87_A	210_F	1.882	0.99
265_G	270_D	1.878	0.99
378_L	383_V	1.861	0.99
363_L	383_V	1.858	0.99
20_L	31_L	1.833	0.99
38_A	42_A	1.831	0.99
364_A	368_R	1.829	0.99
15_V	18_L	1.828	0.99
264_G	270_D	1.790	0.99
247_L	272_L	1.783	0.99
3_L	239_G	1.776	0.99
20_L	29_V	1.773	0.99
395_I	399_L	1.760	0.99
122_F	130_V	1.760	0.99
18_L	24_L	1.757	0.99
364_A	383_V	1.748	0.99
210_F	294_A	1.745	0.99
73_W	77_A	1.723	0.99
159_L	183_A	1.716	0.99
326_D	329_D	1.709	0.99
224_R	297_T	1.703	0.99
18_L	23_R	1.699	0.99
233_A	237_G	1.692	0.99
88_E	147_D	1.691	0.99
115_E	134_R	1.681	0.99
98_I	193_L	1.681	0.99
226_P	300_G	1.667	0.99
114_R	121_T	1.649	0.99
141_F	167_G	1.645	0.99
319_T	395_I	1.640	0.98
16_L	29_V	1.624	0.98
134_R	137_A	1.622	0.98
123_G	130_V	1.599	0.98
45_T	48_R	1.590	0.98
63_R	66_E	1.581	0.98
8_V	257_C	1.564	0.98
228_P	300_G	1.563	0.98
94_I	210_F	1.560	0.98
66_E	71_D	1.556	0.98
324_L	408_I	1.553	0.98
379_P	382_K	1.552	0.98
160_T	163_D	1.537	0.98
40_Y	395_I	1.534	0.98
72_R	115_E	1.498	0.97
88_E	92_A	1.484	0.97
316_F	359_L	1.479	0.97
18_L	263_L	1.461	0.97
16_L	31_L	1.457	0.97
344_V	416_V	1.451	0.97
143_S	155_A	1.447	0.97
44_V	49_Y	1.443	0.97
188_R	191_E	1.441	0.97
98_I	206_P	1.440	0.96
341_A	411_I	1.438	0.96
48_R	385_E	1.423	0.96
200_F	237_G	1.417	0.96
40_Y	45_T	1.413	0.96
75_E	134_R	1.404	0.96
168_F	176_L	1.404	0.96
193_L	206_P	1.395	0.96
17_A	20_L	1.383	0.96
39_D	43_A	1.381	0.96
129_A	177_V	1.368	0.95
95_D	136_F	1.366	0.95
228_P	303_G	1.361	0.95
20_L	362_R	1.360	0.95
68_G	130_V	1.351	0.95
212_Y	233_A	1.350	0.95
306_G	316_F	1.346	0.95
397_A	403_D	1.336	0.95
13_H	16_L	1.334	0.95
68_G	72_R	1.330	0.95
329_D	342_H	1.322	0.94
366_L	370_R	1.318	0.94
150_R	155_A	1.299	0.94
99_V	141_F	1.292	0.94
117_E	134_R	1.292	0.94
165_A	179_L	1.278	0.93
87_A	214_A	1.277	0.93
287_I	298_V	1.270	0.93
142_S	148_P	1.269	0.93
63_R	288_E	1.267	0.93
196_R	236_D	1.265	0.93
343_E	346_S	1.246	0.92
42_A	365_P	1.240	0.92
31_L	362_R	1.239	0.92
187_R	190_G	1.238	0.92
273_V	354_A	1.237	0.92
151_V	206_P	1.235	0.92
48_R	390_A	1.234	0.92
33_R	36_A	1.221	0.92
94_I	98_I	1.214	0.91
28_R	323_V	1.211	0.91
196_R	199_V	1.211	0.91
230_I	287_I	1.203	0.91
157_A	194_A	1.202	0.91
192_A	240_P	1.202	0.91
14_R	263_L	1.192	0.91
36_A	39_D	1.187	0.90
329_D	340_R	1.182	0.90
37_A	321_V	1.173	0.90
373_L	378_L	1.171	0.90
343_E	411_I	1.167	0.90
192_A	237_G	1.165	0.90
225_L	298_V	1.153	0.89
56_I	378_L	1.146	0.89
130_V	133_L	1.145	0.89
22_G	28_R	1.144	0.89
67_A	129_A	1.142	0.89
363_L	388_T	1.128	0.88
367_V	371_L	1.127	0.88
263_L	270_D	1.126	0.88
38_A	383_V	1.124	0.88
13_H	362_R	1.120	0.88
362_R	365_P	1.113	0.87
91_R	207_G	1.110	0.87
197_P	200_F	1.102	0.87
27_F	351_E	1.100	0.87
212_Y	216_R	1.099	0.87
68_G	120_Q	1.096	0.86
347_E	350_V	1.096	0.86
157_A	191_E	1.091	0.86
113_Y	134_R	1.090	0.86
143_S	150_R	1.087	0.86
77_A	93_L	1.086	0.86
37_A	41_V	1.069	0.85
67_A	130_V	1.066	0.85
28_R	325_R	1.058	0.84
75_E	78_A	1.054	0.84
217_A	223_G	1.054	0.84
95_D	193_L	1.054	0.84
71_D	74_A	1.050	0.84
90_A	210_F	1.050	0.84
267_D	270_D	1.050	0.84
366_L	369_A	1.047	0.84
73_W	93_L	1.046	0.84
229_A	233_A	1.041	0.83
12_A	16_L	1.038	0.83
200_F	208_G	1.037	0.83
58_F	381_A	1.037	0.83
118_T	122_F	1.037	0.83
98_I	238_L	1.036	0.83
56_I	382_K	1.035	0.83
46_R	53_L	1.033	0.83
308_P	357_V	1.032	0.83
72_R	134_R	1.026	0.83
245_S	253_P	1.024	0.82
28_R	322_L	1.021	0.82
230_I	283_T	1.021	0.82
326_D	340_R	1.019	0.82
80_L	83_W	1.015	0.82
66_E	115_E	1.012	0.82
144_D	147_D	1.011	0.82
308_P	316_F	1.009	0.81
5_A	231_L	1.008	0.81
143_S	152_D	1.003	0.81
62_W	97_A	1.003	0.81
246_R	258_W	1.001	0.81
3_L	257_C	1.000	0.81
40_Y	394_E	0.998	0.81
201_G	208_G	0.995	0.81
133_L	137_A	0.994	0.81
227_A	231_L	0.991	0.80
316_F	388_T	0.983	0.80
25_P	347_E	0.982	0.80
192_A	196_R	0.978	0.79
414_G	417_F	0.974	0.79
199_V	212_Y	0.965	0.78
216_R	229_A	0.962	0.78
68_G	115_E	0.960	0.78
128_L	176_L	0.954	0.78
3_L	7_A	0.948	0.77
3_L	236_D	0.944	0.77
37_A	45_T	0.943	0.77
44_V	394_E	0.943	0.77
391_A	395_I	0.941	0.77
142_S	150_R	0.938	0.76
70_V	115_E	0.937	0.76
324_L	329_D	0.937	0.76
209_L	238_L	0.937	0.76
155_A	163_D	0.936	0.76
341_A	409_K	0.936	0.76
383_V	388_T	0.935	0.76
43_A	47_R	0.935	0.76
38_A	367_V	0.923	0.75
58_F	97_A	0.922	0.75
72_R	76_L	0.919	0.75
216_R	225_L	0.914	0.75
37_A	40_Y	0.914	0.75
40_Y	43_A	0.911	0.74
6_A	10_E	0.910	0.74
5_A	228_P	0.909	0.74
115_E	118_T	0.908	0.74
35_D	370_R	0.904	0.74
58_F	301_L	0.902	0.74
67_A	72_R	0.901	0.74
277_K	310_Y	0.900	0.73
19_A	322_L	0.898	0.73
413_D	416_V	0.897	0.73
12_A	358_A	0.896	0.73
43_A	398_E	0.896	0.73
154_A	158_R	0.896	0.73
161_A	165_A	0.894	0.73
70_V	75_E	0.893	0.73
13_H	358_A	0.892	0.73
373_L	383_V	0.891	0.73
161_A	179_L	0.891	0.73
17_A	21_A	0.891	0.73
19_A	29_V	0.891	0.73
394_E	398_E	0.888	0.72
387_G	391_A	0.887	0.72
247_L	259_R	0.886	0.72
85_D	91_R	0.883	0.72
12_A	15_V	0.882	0.72
351_E	354_A	0.879	0.72
226_P	299_T	0.879	0.72
14_R	265_G	0.872	0.71
227_A	304_L	0.872	0.71
395_I	404_G	0.868	0.71
122_F	133_L	0.867	0.71
231_L	235_L	0.864	0.70
11_R	274_P	0.863	0.70
89_R	93_L	0.860	0.70
397_A	402_P	0.859	0.70
224_R	299_T	0.857	0.70
164_L	179_L	0.856	0.70
317_V	324_L	0.855	0.70
330_A	348_L	0.853	0.69
395_I	405_G	0.850	0.69
226_P	229_A	0.849	0.69
216_R	233_A	0.847	0.69
42_A	370_R	0.845	0.69
14_R	18_L	0.844	0.69
393_R	396_A	0.844	0.69
129_A	134_R	0.843	0.68
264_G	267_D	0.842	0.68
201_G	204_P	0.841	0.68
44_V	47_R	0.838	0.68
54_D	382_K	0.823	0.67
7_A	10_E	0.821	0.66
344_V	348_L	0.820	0.66
159_L	162_A	0.819	0.66
291_E	297_T	0.818	0.66
290_L	298_V	0.818	0.66
157_A	190_G	0.818	0.66
364_A	381_A	0.816	0.66
136_F	149_L	0.815	0.66
362_R	366_L	0.813	0.66
151_V	193_L	0.810	0.65
97_A	289_P	0.802	0.65
170_V	175_P	0.792	0.64
77_A	80_L	0.790	0.63
138_A	166_R	0.790	0.63
79_R	349_V	0.789	0.63
81_A	84_L	0.787	0.63
230_I	298_V	0.784	0.63
48_R	394_E	0.780	0.62
200_F	207_G	0.778	0.62
7_A	11_R	0.776	0.62
115_E	130_V	0.775	0.62
90_A	211_D	0.773	0.62
231_L	279_S	0.773	0.62
13_H	17_A	0.769	0.61
365_P	383_V	0.769	0.61
163_D	166_R	0.768	0.61
164_L	183_A	0.768	0.61
85_D	88_E	0.768	0.61
213_L	233_A	0.767	0.61
61_R	64_H	0.765	0.61
139_G	142_S	0.764	0.61
90_A	94_I	0.763	0.61
42_A	373_L	0.763	0.61
275_F	322_L	0.762	0.61
234_L	328_A	0.760	0.60
171_S	175_P	0.760	0.60
98_I	239_G	0.758	0.60
316_F	363_L	0.757	0.60
41_V	387_G	0.756	0.60
14_R	264_G	0.756	0.60
19_A	272_L	0.756	0.60
254_L	257_C	0.756	0.60
365_P	369_A	0.753	0.60
275_F	354_A	0.752	0.60
258_W	345_G	0.750	0.59
209_L	233_A	0.748	0.59
397_A	405_G	0.748	0.59
164_L	304_L	0.746	0.59
208_G	212_Y	0.746	0.59
67_A	122_F	0.746	0.59
325_R	342_H	0.744	0.59
405_G	409_K	0.742	0.59
145_P	148_P	0.740	0.58
122_F	257_C	0.737	0.58
181_G	258_W	0.737	0.58
4_S	8_V	0.734	0.58
76_L	80_L	0.730	0.57
283_T	287_I	0.730	0.57
76_L	133_L	0.729	0.57
16_L	20_L	0.727	0.57
140_A	159_L	0.722	0.56
158_R	196_R	0.721	0.56
15_V	258_W	0.721	0.56
115_E	122_F	0.717	0.56
116_P	134_R	0.715	0.56
72_R	75_E	0.714	0.56
5_A	303_G	0.712	0.55
44_V	48_R	0.709	0.55
15_V	19_A	0.708	0.55
88_E	208_G	0.704	0.55
77_A	89_R	0.701	0.54
16_L	19_A	0.699	0.54
325_R	370_R	0.699	0.54
196_R	240_P	0.698	0.54
2_L	7_A	0.697	0.54
214_A	217_A	0.696	0.54
213_L	225_L	0.693	0.53
351_E	355_L	0.688	0.53
92_A	206_P	0.687	0.53
366_L	383_V	0.687	0.53
60_S	382_K	0.687	0.53
45_T	257_C	0.687	0.53
6_A	228_P	0.687	0.53
3_L	8_V	0.687	0.53
358_A	362_R	0.686	0.53
207_G	211_D	0.685	0.53
153_A	194_A	0.685	0.53
8_V	12_A	0.685	0.53
110_A	403_D	0.684	0.52
258_W	412_S	0.682	0.52
89_R	292_W	0.682	0.52
118_T	202_R	0.682	0.52
195_A	215_A	0.682	0.52
228_P	299_T	0.682	0.52
45_T	367_V	0.677	0.52
386_G	390_A	0.676	0.52
291_E	301_L	0.676	0.52
378_L	382_K	0.675	0.52
275_F	351_E	0.674	0.51
94_I	233_A	0.670	0.51
2_L	11_R	0.670	0.51
76_L	99_V	0.668	0.51
246_R	412_S	0.665	0.50
136_F	206_P	0.665	0.50
350_V	408_I	0.664	0.50
378_L	388_T	0.662	0.50
280_Q	305_T	0.661	0.50
191_E	296_I	0.660	0.50
412_S	415_T	0.659	0.50
66_E	73_W	0.659	0.50
100_S	132_S	0.658	0.50
232_S	236_D	0.658	0.50
65_F	133_L	0.656	0.50
45_T	60_S	0.654	0.49
200_F	212_Y	0.652	0.49
15_V	260_H	0.652	0.49
206_P	237_G	0.650	0.49
26_H	351_E	0.650	0.49
7_A	239_G	0.648	0.49
265_G	269_T	0.647	0.49
106_G	309_E	0.647	0.49
16_L	316_F	0.647	0.49
73_W	97_A	0.647	0.49
53_L	282_L	0.646	0.48
29_V	359_L	0.645	0.48
62_W	288_E	0.645	0.48
138_A	141_F	0.645	0.48
94_I	230_I	0.643	0.48
49_Y	58_F	0.643	0.48
90_A	207_G	0.643	0.48
210_F	214_A	0.643	0.48
68_G	122_F	0.643	0.48
177_V	308_P	0.642	0.48
283_T	304_L	0.641	0.48
290_L	301_L	0.640	0.48
49_Y	53_L	0.640	0.48
15_V	24_L	0.637	0.47
90_A	294_A	0.636	0.47
181_G	412_S	0.633	0.47
113_Y	322_L	0.633	0.47
231_L	239_G	0.630	0.47
66_E	130_V	0.630	0.47
147_D	155_A	0.630	0.47
217_A	222_G	0.628	0.47
386_G	391_A	0.628	0.47
125_S	309_E	0.624	0.46
80_L	93_L	0.621	0.46
134_R	138_A	0.620	0.46
56_I	308_P	0.619	0.46
26_H	347_E	0.618	0.45
187_R	191_E	0.617	0.45
190_G	194_A	0.616	0.45
364_A	379_P	0.616	0.45
33_R	319_T	0.613	0.45
279_S	288_E	0.612	0.45
151_V	155_A	0.611	0.45
37_A	70_V	0.607	0.44
358_A	363_L	0.607	0.44
62_W	289_P	0.606	0.44
375_A	379_P	0.605	0.44
325_R	351_E	0.604	0.44
263_L	271_G	0.604	0.44
206_P	225_L	0.604	0.44
158_R	195_A	0.603	0.44
191_E	195_A	0.603	0.44
259_R	269_T	0.602	0.44
316_F	360_L	0.602	0.44
12_A	18_L	0.602	0.44
70_V	130_V	0.600	0.44
129_A	385_E	0.598	0.43
47_R	85_D	0.598	0.43
13_H	322_L	0.595	0.43
227_A	235_L	0.595	0.43
277_K	309_E	0.595	0.43
80_L	88_E	0.593	0.43
264_G	269_T	0.592	0.43
213_L	234_L	0.592	0.43
327_P	346_S	0.592	0.43
259_R	267_D	0.591	0.43
15_V	263_L	0.590	0.43
308_P	390_A	0.589	0.42
326_D	330_A	0.589	0.42
24_L	60_S	0.587	0.42
112_R	173_D	0.587	0.42
65_F	280_Q	0.586	0.42
291_E	382_K	0.584	0.42
144_D	150_R	0.584	0.42
135_M	140_A	0.582	0.42
106_G	277_K	0.581	0.42
201_G	205_R	0.579	0.41
22_G	48_R	0.575	0.41
129_A	409_K	0.574	0.41
158_R	191_E	0.573	0.41
365_P	368_R	0.572	0.41
22_G	31_L	0.572	0.41
392_G	396_A	0.572	0.41
99_V	135_M	0.572	0.41
207_G	212_Y	0.572	0.41
99_V	155_A	0.571	0.41
34_L	121_T	0.571	0.41
321_V	359_L	0.571	0.41
155_A	160_T	0.567	0.40
227_A	260_H	0.567	0.40
97_A	151_V	0.567	0.40
350_V	410_I	0.566	0.40
16_L	359_L	0.564	0.40
58_F	385_E	0.563	0.40
42_A	46_R	0.563	0.40
130_V	134_R	0.562	0.40
346_S	363_L	0.562	0.40
80_L	92_A	0.562	0.40
210_F	230_I	0.560	0.39
217_A	296_I	0.560	0.39
192_A	195_A	0.560	0.39
217_A	225_L	0.558	0.39
374_D	378_L	0.556	0.39
42_A	378_L	0.555	0.39
320_G	323_V	0.555	0.39
339_A	394_E	0.555	0.39
108_G	125_S	0.554	0.39
64_H	310_Y	0.554	0.39
288_E	388_T	0.552	0.39
43_A	394_E	0.552	0.39
348_L	408_I	0.552	0.39
308_P	317_V	0.552	0.39
196_R	237_G	0.551	0.39
89_R	147_D	0.551	0.39
70_V	120_Q	0.551	0.39
74_A	78_A	0.551	0.39
106_G	125_S	0.551	0.39
106_G	310_Y	0.550	0.38
31_L	316_F	0.549	0.38
215_A	249_L	0.549	0.38
277_K	312_N	0.548	0.38
113_Y	369_A	0.547	0.38
115_E	137_A	0.547	0.38
188_R	203_E	0.546	0.38
18_L	271_G	0.545	0.38
109_P	319_T	0.544	0.38
236_D	239_G	0.544	0.38
109_P	129_A	0.543	0.38
76_L	136_F	0.543	0.38
213_L	230_I	0.542	0.38
15_V	22_G	0.542	0.38
134_R	252_V	0.541	0.38
8_V	303_G	0.539	0.37
171_S	248_T	0.539	0.37
155_A	167_G	0.538	0.37
2_L	9_R	0.536	0.37
192_A	246_R	0.536	0.37
60_S	66_E	0.535	0.37
289_P	295_G	0.535	0.37
389_W	393_R	0.534	0.37
17_A	56_I	0.534	0.37
189_L	241_I	0.534	0.37
117_E	120_Q	0.534	0.37
100_S	106_G	0.534	0.37
147_D	238_L	0.533	0.37
63_R	364_A	0.533	0.37
45_T	385_E	0.532	0.37
33_R	323_V	0.532	0.37
241_I	416_V	0.531	0.37
257_C	385_E	0.531	0.37
278_L	310_Y	0.531	0.37
151_V	223_G	0.529	0.36
259_R	347_E	0.529	0.36
166_R	171_S	0.528	0.36
400_R	407_P	0.528	0.36
60_S	63_R	0.527	0.36
322_L	374_D	0.527	0.36
368_R	375_A	0.526	0.36
58_F	94_I	0.526	0.36
67_A	115_E	0.526	0.36
364_A	382_K	0.525	0.36
18_L	21_A	0.524	0.36
58_F	382_K	0.523	0.36
326_D	348_L	0.523	0.36
74_A	179_L	0.523	0.36
167_G	316_F	0.523	0.36
216_R	224_R	0.522	0.36
123_G	404_G	0.520	0.35
20_L	24_L	0.520	0.35
355_L	359_L	0.519	0.35
85_D	211_D	0.518	0.35
40_Y	44_V	0.517	0.35
108_G	311_R	0.516	0.35
73_W	83_W	0.516	0.35
75_E	79_R	0.515	0.35
113_Y	375_A	0.514	0.35
58_F	162_A	0.514	0.35
45_T	187_R	0.513	0.35
181_G	246_R	0.513	0.35
379_P	387_G	0.511	0.35
193_L	237_G	0.509	0.34
107_A	243_P	0.508	0.34
165_A	270_D	0.508	0.34
10_E	13_H	0.507	0.34
132_S	279_S	0.507	0.34
49_Y	346_S	0.507	0.34
233_A	257_C	0.507	0.34
233_A	236_D	0.506	0.34
42_A	45_T	0.506	0.34
21_A	36_A	0.506	0.34
62_W	152_D	0.506	0.34
94_I	234_L	0.505	0.34
110_A	317_V	0.505	0.34
84_L	349_V	0.505	0.34
402_P	405_G	0.505	0.34
245_S	308_P	0.503	0.34
164_L	383_V	0.502	0.34
261_P	264_G	0.501	0.34
393_R	400_R	0.500	0.34
344_V	349_V	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ts7A	2	0.1295	34.6	0.981	Contact Map
4f62A	2	0.1007	31.4	0.981	Contact Map
2c4bA	2	0.1271	29.4	0.982	Contact Map
1tizA	1	0.1559	14.6	0.984	Contact Map
3h4mA	1	0.1103	14.1	0.984	Contact Map
2ycuA	1	0.1511	14	0.984	Contact Map
1mbaA	1	0.223	14	0.984	Contact Map
4uz0A	1	0.1079	13.5	0.984	Contact Map
1bm9A	2	0.1175	12.3	0.985	Contact Map
1c3pA	1	0.2038	10.8	0.985	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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