GREMLIN Database
YhhN - YhhN-like protein
PFAM: PF07947 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 185 (182)
Sequences: 12434 (9999)
Seq/√Len: 741.2
META: 0.833

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_S64_A5.1791.00
122_A148_V4.1361.00
62_L117_V3.6111.00
68_Y178_Q3.2581.00
153_L169_L2.8441.00
41_L60_A2.6421.00
69_I124_A2.3721.00
45_L60_A2.3451.00
8_P47_M2.2791.00
32_L71_A2.2531.00
8_P44_V2.1971.00
97_L101_W2.1971.00
163_F166_A2.1151.00
126_L141_A2.0841.00
73_L124_A2.0531.00
119_S148_V2.0111.00
92_A152_S1.9921.00
4_Y47_M1.9501.00
38_F63_L1.9431.00
101_W108_R1.9371.00
11_M14_L1.9171.00
63_L67_A1.8971.00
126_L145_L1.8931.00
45_L56_A1.8881.00
121_M144_A1.8791.00
66_L70_A1.8651.00
34_A67_A1.7711.00
140_V184_G1.7581.00
39_S178_Q1.7541.00
46_L57_G1.7501.00
143_G181_I1.7361.00
146_L176_L1.7091.00
12_L40_L1.6731.00
171_M175_Y1.6591.00
69_I120_A1.6451.00
93_A119_S1.5751.00
36_L182_A1.5701.00
10_L175_Y1.5511.00
95_A99_L1.4981.00
31_L70_A1.4971.00
156_L160_V1.4891.00
42_G60_A1.4521.00
38_F67_A1.4461.00
103_G160_V1.4251.00
157_N166_A1.4151.00
58_L62_L1.4081.00
122_A145_L1.3961.00
37_L41_L1.3851.00
101_W104_L1.3701.00
179_L183_L1.3061.00
35_A68_Y1.3051.00
125_A144_A1.2881.00
78_L82_R1.2841.00
154_L170_I1.2791.00
89_L122_A1.2691.00
72_F121_M1.2561.00
15_I33_L1.2351.00
128_R140_V1.2351.00
168_L172_L1.2131.00
40_L44_V1.1971.00
35_A71_A1.1911.00
41_L45_L1.1871.00
11_M175_Y1.1681.00
149_L173_T1.1631.00
170_I173_T1.1561.00
6_T10_L1.1531.00
84_L88_P1.1481.00
31_L67_A1.1391.00
15_I37_L1.1361.00
165_L168_L1.1251.00
52_R56_A1.1231.00
3_R6_T1.1201.00
122_A144_A1.1121.00
128_R137_A1.1121.00
16_L20_L1.1121.00
79_L83_L1.1021.00
19_L33_L1.1001.00
146_L173_T1.0991.00
50_P53_F1.0861.00
176_L180_L1.0841.00
28_Y184_G1.0841.00
65_H147_F1.0821.00
15_I36_L1.0811.00
173_T177_A1.0691.00
54_F158_R1.0681.00
65_H69_I1.0561.00
28_Y71_A1.0451.00
128_R136_G1.0401.00
139_L183_L1.0271.00
88_P91_L1.0261.00
96_L152_S1.0091.00
97_L115_A1.0061.00
28_Y32_L0.9961.00
166_A170_I0.9921.00
58_L110_P0.9841.00
14_L18_A0.9841.00
10_L13_L0.9701.00
92_A96_L0.9661.00
157_N162_P0.9631.00
97_L112_L0.9631.00
15_I40_L0.9611.00
55_L59_A0.9571.00
72_F140_V0.9441.00
39_S68_Y0.9431.00
114_Y151_D0.9391.00
163_F169_L0.9391.00
58_L111_V0.9391.00
143_G180_L0.9331.00
65_H117_V0.9161.00
165_L169_L0.9151.00
30_R34_A0.9011.00
101_W112_L0.8981.00
58_L155_A0.8801.00
109_I113_V0.8741.00
149_L153_L0.8631.00
55_L107_L0.8621.00
143_G177_A0.8551.00
118_I121_M0.8531.00
82_R86_L0.8511.00
38_F60_A0.8491.00
45_L53_F0.8441.00
11_M178_Q0.8431.00
4_Y8_P0.8391.00
55_L110_P0.8361.00
31_L71_A0.8331.00
107_L110_P0.8321.00
118_I144_A0.8311.00
53_F56_A0.8241.00
157_N170_I0.8161.00
150_S173_T0.8121.00
139_L180_L0.8111.00
14_L182_A0.8101.00
32_L181_I0.8051.00
153_L170_I0.8021.00
17_L183_L0.7991.00
62_L113_V0.7971.00
25_A29_R0.7941.00
94_A98_A0.7891.00
138_L142_A0.7851.00
91_L95_A0.7811.00
54_F58_L0.7711.00
99_L160_V0.7651.00
26_S30_R0.7611.00
40_L175_Y0.7531.00
157_N167_R0.7481.00
172_L175_Y0.7461.00
11_M18_A0.7451.00
80_P83_L0.7431.00
93_A115_A0.7381.00
100_L103_G0.7371.00
11_M40_L0.7361.00
14_L17_L0.7361.00
109_I112_L0.7331.00
125_A140_V0.7311.00
77_G82_R0.7301.00
11_M15_I0.7281.00
155_A159_F0.7281.00
59_A63_L0.7241.00
30_R33_L0.7231.00
65_H177_A0.7221.00
10_L171_M0.7211.00
18_A33_L0.7201.00
157_N163_F0.7181.00
70_A73_L0.7141.00
8_P12_L0.7131.00
35_A67_A0.7111.00
115_A118_I0.6991.00
10_L40_L0.6951.00
156_L166_A0.6941.00
56_A60_A0.6931.00
71_A140_V0.6921.00
22_G25_A0.6911.00
167_R170_I0.6911.00
77_G81_L0.6891.00
153_L172_L0.6891.00
49_L52_R0.6821.00
18_A32_L0.6821.00
61_F174_Y0.6811.00
105_G108_R0.6801.00
12_L16_L0.6801.00
83_L87_L0.6791.00
26_S29_R0.6721.00
43_D46_L0.6711.00
169_L172_L0.6701.00
10_L14_L0.6701.00
149_L154_L0.6691.00
145_L149_L0.6621.00
17_L20_L0.6621.00
89_L92_A0.6611.00
86_L123_A0.6581.00
148_V152_S0.6571.00
100_L104_L0.6561.00
156_L163_F0.6501.00
79_L82_R0.6411.00
10_L18_A0.6391.00
172_L176_L0.6341.00
43_D174_Y0.6321.00
85_L89_L0.6321.00
46_L54_F0.6291.00
155_A158_R0.6291.00
144_A181_I0.6281.00
77_G80_P0.6241.00
95_A98_A0.6241.00
129_L141_A0.6231.00
93_A97_L0.6221.00
65_H151_D0.6221.00
76_G80_P0.6211.00
75_R79_L0.6201.00
129_L138_L0.6171.00
69_I73_L0.6141.00
99_L102_P0.6101.00
136_G140_V0.6071.00
156_L161_R0.6061.00
133_S137_A0.6051.00
116_L120_A0.6021.00
120_A124_A0.6021.00
11_M36_L0.6011.00
38_F41_L0.6001.00
153_L173_T0.6001.00
134_A138_L0.5981.00
153_L163_F0.5971.00
15_I19_L0.5971.00
56_A59_A0.5961.00
133_S136_G0.5961.00
177_A180_L0.5931.00
129_L137_A0.5901.00
147_F151_D0.5881.00
38_F42_G0.5841.00
108_R112_L0.5831.00
7_K14_L0.5801.00
49_L53_F0.5781.00
18_A29_R0.5701.00
125_A141_A0.5681.00
33_L37_L0.5681.00
128_R132_L0.5681.00
106_A110_P0.5671.00
96_L115_A0.5651.00
27_R31_L0.5621.00
162_P166_A0.5621.00
89_L93_A0.5611.00
107_L159_F0.5601.00
64_A68_Y0.5601.00
96_L99_L0.5581.00
27_R30_R0.5511.00
42_G61_F0.5491.00
177_A181_I0.5491.00
96_L100_L0.5481.00
7_K46_L0.5471.00
85_L88_P0.5441.00
83_L86_L0.5371.00
92_A95_A0.5361.00
147_F177_A0.5351.00
84_L87_L0.5331.00
98_A102_P0.5331.00
78_L85_L0.5311.00
69_I117_V0.5271.00
99_L156_L0.5261.00
78_L81_L0.5241.00
118_I122_A0.5241.00
18_A36_L0.5231.00
75_R78_L0.5231.00
144_A177_A0.5221.00
153_L166_A0.5191.00
175_Y179_L0.5181.00
134_A137_A0.5171.00
130_L133_S0.5151.00
28_Y31_L0.5141.00
97_L104_L0.5131.00
137_A141_A0.5111.00
74_R78_L0.5071.00
88_P92_A0.5051.00
58_L159_F0.5051.00
124_A127_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4qtnA 3 0.8649 7.5 0.918 Contact Map
3l1lA 2 0.4486 2.7 0.934 Contact Map
3b5dA 2 0.5297 2.3 0.937 Contact Map
4njnA 4 0.6757 1.4 0.943 Contact Map
3m73A 3 0.5676 1.4 0.943 Contact Map
2i68A 2 0.4216 1.4 0.944 Contact Map
1wazA 1 0.1514 1.4 0.944 Contact Map
4xtrG 1 0.1189 1 0.949 Contact Map
2h3oA 1 0.1568 0.8 0.952 Contact Map
1vkoA 4 0.3027 0.7 0.953 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.