TraG_N - PFAM28P - GREMLIN Contacts

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TraG_N - TraG-like protein, N-terminal region

PFAM:	PF07916	Sequences: EIYTYGGGWILYNVLNAVAMIFGSGDYDSLVATGLLLGLLIALWLAAREEKGGLSLRRIEKWLLVALLVYLLLFVPKVTVTIEDRTQPTGSVPTVDNVPLGLALVASLSSGIGYALTEAIETAFSLPDLLSYSKTGMLFGRQLLMEVRNARITDPVLAQELQDFVRDCVLPDILLTNGKYSLDDLLNSPDLYDTLRSPARTVSGTYPTCKEAWSGLRARLLAEVDPGLATRLAAAAGGFGGADAAAALLASALGDAYQYLTGASQSASAQDILRQALLINALRDASQTLANAVNDAAADAGLAAGSLAYAAAQAEAQQRSSWAAAGDLARQALPMLQAVLEALIYALFPLVLLLSLYPGKGLKVLKGYLFALIWLQLWPPLAAILNSILLDALYGSLAARAAHSNLGLGGLTLATADGIYSAASDLLAVAGYLFLSIPLLALALLKGGGAAGSSLAGALGGAAQSAE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	467 (463)
Sequences:	1861 (1440)
Seq/√Len:	66.9
META:	0.673

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
80_V	103_A	4.507	1.00
15_L	82_I	4.357	1.00
79_T	96_D	4.326	1.00
78_V	103_A	4.191	1.00
160_E	219_R	3.888	1.00
208_T	211_E	3.857	1.00
190_D	193_D	3.537	1.00
117_T	121_E	3.494	1.00
2_I	15_L	3.443	1.00
16_N	19_A	3.434	1.00
16_N	97_N	3.319	1.00
163_D	167_D	3.295	1.00
346_A	384_I	3.286	1.00
381_L	441_A	3.150	1.00
157_L	220_L	3.130	1.00
207_P	211_E	3.100	1.00
363_K	366_K	3.081	1.00
113_G	376_Q	3.016	1.00
192_Y	217_R	2.827	1.00
1_E	83_E	2.809	1.00
207_P	212_A	2.735	1.00
117_T	380_P	2.694	1.00
198_P	202_V	2.685	1.00
114_Y	118_E	2.653	1.00
199_A	202_V	2.628	1.00
102_L	348_F	2.621	1.00
30_L	112_I	2.577	1.00
12_Y	16_N	2.569	1.00
198_P	201_T	2.549	1.00
207_P	215_G	2.515	1.00
181_S	184_D	2.422	1.00
85_R	114_Y	2.420	1.00
271_D	274_R	2.410	1.00
160_E	212_A	2.385	1.00
341_E	345_Y	2.379	1.00
337_Q	341_E	2.370	1.00
73_L	101_G	2.357	1.00
331_Q	425_D	2.330	1.00
16_N	20_M	2.294	1.00
448_G	452_G	2.294	1.00
17_A	124_F	2.244	1.00
106_A	345_Y	2.234	1.00
82_I	95_V	2.227	1.00
371_A	375_L	2.188	1.00
107_S	111_G	2.180	1.00
448_G	451_A	2.130	1.00
450_A	453_S	2.085	1.00
81_T	92_V	2.081	1.00
202_V	212_A	2.061	1.00
326_G	432_Y	2.038	1.00
188_S	194_T	2.035	1.00
19_A	97_N	2.019	1.00
449_G	453_S	2.012	1.00
168_C	209_C	2.007	1.00
35_L	66_A	1.990	1.00
446_K	450_A	1.987	1.00
12_Y	82_I	1.986	1.00
382_A	434_F	1.975	1.00
137_M	140_G	1.944	1.00
381_L	437_I	1.922	1.00
377_L	441_A	1.917	1.00
329_A	334_P	1.913	1.00
4_T	7_G	1.891	1.00
14_V	342_A	1.890	1.00
386_N	390_L	1.877	1.00
192_Y	213_W	1.865	1.00
319_R	425_D	1.859	1.00
38_G	42_A	1.820	1.00
4_T	11_L	1.814	1.00
18_V	102_L	1.778	1.00
106_A	341_E	1.751	1.00
21_I	119_A	1.738	1.00
374_W	378_W	1.736	1.00
232_L	236_A	1.734	1.00
161_L	220_L	1.734	1.00
275_Q	279_I	1.719	1.00
452_G	456_A	1.713	1.00
2_I	80_V	1.712	1.00
108_L	350_L	1.700	0.99
341_E	375_L	1.700	0.99
17_A	20_M	1.697	0.99
128_D	134_K	1.683	0.99
374_W	441_A	1.674	0.99
341_E	376_Q	1.654	0.99
446_K	449_G	1.646	0.99
315_E	331_Q	1.640	0.99
349_P	353_L	1.626	0.99
385_L	437_I	1.605	0.99
19_A	96_D	1.590	0.99
105_V	109_S	1.588	0.99
10_I	342_A	1.584	0.99
455_L	458_A	1.538	0.99
143_L	147_V	1.518	0.99
197_S	202_V	1.482	0.99
215_G	219_R	1.477	0.99
114_Y	133_S	1.477	0.99
270_Q	274_R	1.471	0.99
412_T	415_T	1.461	0.98
251_S	255_D	1.459	0.98
154_D	219_R	1.456	0.98
197_S	201_T	1.435	0.98
316_A	319_R	1.429	0.98
318_Q	322_W	1.424	0.98
236_A	239_F	1.423	0.98
19_A	79_T	1.418	0.98
344_I	372_L	1.410	0.98
157_L	219_R	1.409	0.98
95_V	98_V	1.399	0.98
112_I	115_A	1.391	0.98
233_A	237_G	1.388	0.98
15_L	18_V	1.385	0.98
5_Y	337_Q	1.383	0.98
197_S	200_R	1.380	0.98
196_R	217_R	1.364	0.98
138_L	430_A	1.363	0.98
4_T	372_L	1.340	0.97
14_V	346_A	1.332	0.97
180_Y	184_D	1.330	0.97
80_V	98_V	1.321	0.97
372_L	375_L	1.314	0.97
2_I	345_Y	1.313	0.97
442_L	446_K	1.309	0.97
205_T	215_G	1.305	0.97
141_R	423_A	1.299	0.97
329_A	333_L	1.294	0.97
120_I	387_S	1.291	0.97
337_Q	379_P	1.286	0.96
131_S	134_K	1.273	0.96
387_S	391_D	1.263	0.96
115_A	119_A	1.263	0.96
6_G	10_I	1.257	0.96
423_A	426_L	1.255	0.96
374_W	456_A	1.252	0.96
217_R	221_L	1.251	0.96
411_L	415_T	1.249	0.96
375_L	378_W	1.240	0.96
184_D	194_T	1.240	0.96
257_Y	276_A	1.238	0.96
370_F	442_L	1.234	0.96
172_D	200_R	1.229	0.95
280_N	312_A	1.221	0.95
21_I	350_L	1.221	0.95
379_P	382_A	1.219	0.95
142_Q	146_E	1.217	0.95
188_S	192_Y	1.209	0.95
450_A	456_A	1.206	0.95
263_A	266_S	1.202	0.95
389_L	430_A	1.198	0.95
447_G	452_G	1.192	0.95
190_D	194_T	1.189	0.95
159_Q	163_D	1.188	0.95
193_D	210_K	1.186	0.94
13_N	387_S	1.185	0.94
173_I	180_Y	1.181	0.94
120_I	380_P	1.178	0.94
161_L	216_L	1.177	0.94
15_L	106_A	1.176	0.94
156_V	160_E	1.164	0.94
261_T	265_Q	1.164	0.94
213_W	217_R	1.163	0.94
39_L	43_L	1.160	0.94
113_G	341_E	1.159	0.94
338_A	426_L	1.158	0.94
105_V	369_L	1.157	0.94
87_Q	114_Y	1.148	0.93
374_W	377_L	1.147	0.93
235_A	239_F	1.144	0.93
397_L	423_A	1.144	0.93
19_A	22_F	1.138	0.93
348_F	368_Y	1.136	0.93
232_L	239_F	1.135	0.93
374_W	380_P	1.134	0.93
263_A	268_S	1.133	0.93
349_P	438_P	1.131	0.93
193_D	196_R	1.126	0.93
374_W	445_L	1.108	0.92
90_G	93_P	1.106	0.92
40_L	64_L	1.103	0.92
234_A	237_G	1.099	0.92
352_L	355_S	1.090	0.92
266_S	271_D	1.087	0.91
9_W	12_Y	1.084	0.91
289_L	292_A	1.077	0.91
297_A	301_G	1.076	0.91
280_N	283_R	1.073	0.91
338_A	358_P	1.073	0.91
393_L	407_G	1.070	0.91
121_E	386_N	1.067	0.91
70_Y	101_G	1.061	0.90
19_A	122_T	1.059	0.90
335_M	426_L	1.053	0.90
271_D	275_Q	1.049	0.90
87_Q	90_G	1.048	0.90
429_V	434_F	1.046	0.90
337_Q	376_Q	1.044	0.90
178_G	181_S	1.040	0.89
11_L	15_L	1.038	0.89
309_Y	313_Q	1.034	0.89
68_L	347_L	1.029	0.89
313_Q	317_Q	1.028	0.89
248_L	252_A	1.027	0.89
70_Y	74_F	1.026	0.89
318_Q	341_E	1.025	0.89
136_G	139_F	1.025	0.89
2_I	106_A	1.021	0.89
337_Q	389_L	1.019	0.89
196_R	213_W	1.019	0.89
3_Y	83_E	1.017	0.88
458_A	463_A	1.017	0.88
451_A	455_L	1.015	0.88
132_Y	135_T	1.013	0.88
347_L	444_L	1.013	0.88
18_V	98_V	1.008	0.88
18_V	213_W	1.008	0.88
459_L	462_A	1.007	0.88
195_L	221_L	1.005	0.88
439_L	454_S	1.002	0.88
443_A	452_G	1.001	0.88
277_L	312_A	0.999	0.88
428_A	431_G	0.998	0.87
99_P	209_C	0.997	0.87
98_V	103_A	0.994	0.87
191_L	279_I	0.994	0.87
172_D	175_L	0.992	0.87
7_G	106_A	0.989	0.87
339_V	429_V	0.989	0.87
453_S	456_A	0.980	0.87
172_D	180_Y	0.979	0.86
339_V	430_A	0.978	0.86
432_Y	435_L	0.972	0.86
63_L	333_L	0.970	0.86
154_D	183_D	0.966	0.86
147_V	276_A	0.965	0.86
231_R	234_A	0.958	0.85
99_P	168_C	0.952	0.85
21_I	123_A	0.947	0.85
355_S	377_L	0.945	0.84
89_T	93_P	0.944	0.84
342_A	345_Y	0.939	0.84
376_Q	379_P	0.936	0.84
113_G	322_W	0.935	0.84
19_A	98_V	0.934	0.84
59_I	347_L	0.933	0.84
191_L	278_L	0.931	0.84
88_P	93_P	0.931	0.84
29_S	33_T	0.923	0.83
172_D	178_G	0.920	0.83
314_A	328_L	0.920	0.83
447_G	455_L	0.915	0.82
165_V	285_A	0.912	0.82
172_D	177_N	0.909	0.82
188_S	193_D	0.907	0.82
377_L	380_P	0.906	0.82
169_V	185_L	0.902	0.82
19_A	123_A	0.901	0.81
80_V	110_S	0.900	0.81
305_G	308_A	0.896	0.81
113_G	379_P	0.895	0.81
203_S	218_A	0.894	0.81
123_A	350_L	0.890	0.81
30_L	353_L	0.890	0.81
188_S	191_L	0.890	0.81
392_A	426_L	0.887	0.80
1_E	7_G	0.886	0.80
355_S	365_L	0.885	0.80
279_I	412_T	0.884	0.80
359_G	382_A	0.882	0.80
234_A	238_G	0.880	0.80
83_E	90_G	0.877	0.80
432_Y	442_L	0.874	0.79
336_L	340_L	0.873	0.79
59_I	354_L	0.870	0.79
218_A	222_A	0.867	0.79
334_P	431_G	0.866	0.79
235_A	238_G	0.866	0.79
131_S	138_L	0.866	0.79
450_A	454_S	0.865	0.79
271_D	411_L	0.862	0.79
343_L	437_I	0.861	0.78
130_L	137_M	0.855	0.78
317_Q	321_S	0.852	0.78
12_Y	93_P	0.851	0.78
430_A	438_P	0.849	0.77
177_N	185_L	0.849	0.77
216_L	220_L	0.848	0.77
439_L	446_K	0.848	0.77
290_A	294_N	0.847	0.77
125_S	132_Y	0.847	0.77
120_I	352_L	0.847	0.77
310_A	324_A	0.846	0.77
74_F	101_G	0.845	0.77
455_L	461_G	0.843	0.77
353_L	452_G	0.842	0.77
273_L	283_R	0.842	0.77
216_L	368_Y	0.840	0.77
276_A	279_I	0.840	0.77
380_P	383_A	0.839	0.77
375_L	379_P	0.839	0.77
29_S	115_A	0.839	0.77
355_S	444_L	0.838	0.77
448_G	458_A	0.836	0.76
325_A	431_G	0.833	0.76
456_A	463_A	0.832	0.76
102_L	107_S	0.830	0.76
192_Y	278_L	0.829	0.76
218_A	264_S	0.829	0.76
243_D	247_A	0.828	0.76
185_L	188_S	0.828	0.76
443_A	453_S	0.825	0.75
258_Q	460_G	0.825	0.75
160_E	204_G	0.823	0.75
175_L	197_S	0.821	0.75
403_H	407_G	0.820	0.75
192_Y	220_L	0.819	0.75
157_L	161_L	0.818	0.75
232_L	235_A	0.817	0.75
138_L	167_D	0.816	0.75
121_E	322_W	0.816	0.75
381_L	385_L	0.814	0.74
238_G	241_G	0.811	0.74
173_I	181_S	0.808	0.74
117_T	383_A	0.807	0.74
339_V	433_L	0.802	0.73
102_L	105_V	0.800	0.73
382_A	386_N	0.800	0.73
102_L	106_A	0.800	0.73
135_T	138_L	0.799	0.73
173_I	260_L	0.799	0.73
9_W	334_P	0.797	0.73
107_S	177_N	0.796	0.73
420_Y	423_A	0.791	0.72
422_A	429_V	0.790	0.72
384_I	446_K	0.789	0.72
363_K	367_G	0.789	0.72
7_G	337_Q	0.788	0.72
364_V	368_Y	0.788	0.72
17_A	438_P	0.787	0.72
94_T	97_N	0.786	0.72
172_D	179_K	0.784	0.72
457_G	462_A	0.784	0.72
156_V	351_V	0.784	0.72
414_A	417_D	0.783	0.72
116_L	187_N	0.783	0.72
281_A	285_A	0.780	0.71
24_S	119_A	0.779	0.71
372_L	445_L	0.776	0.71
231_R	235_A	0.774	0.71
288_T	291_N	0.773	0.71
75_V	101_G	0.773	0.71
298_A	301_G	0.770	0.70
144_L	385_L	0.770	0.70
289_L	293_V	0.769	0.70
147_V	253_L	0.768	0.70
276_A	280_N	0.768	0.70
347_L	381_L	0.766	0.70
115_A	184_D	0.765	0.70
458_A	464_Q	0.763	0.70
23_G	26_D	0.761	0.69
333_L	378_W	0.761	0.69
38_G	378_W	0.759	0.69
452_G	460_G	0.758	0.69
164_F	318_Q	0.755	0.69
65_V	368_Y	0.755	0.69
452_G	458_A	0.754	0.69
441_A	449_G	0.751	0.68
437_I	441_A	0.751	0.68
427_L	430_A	0.750	0.68
330_R	428_A	0.750	0.68
68_L	117_T	0.749	0.68
402_A	405_N	0.747	0.68
253_L	281_A	0.743	0.68
441_A	445_L	0.742	0.67
139_F	379_P	0.742	0.67
164_F	345_Y	0.739	0.67
141_R	393_L	0.739	0.67
120_I	350_L	0.739	0.67
297_A	304_A	0.738	0.67
23_G	29_S	0.737	0.67
3_Y	17_A	0.733	0.67
216_L	300_A	0.732	0.66
396_S	431_G	0.732	0.66
268_S	271_D	0.732	0.66
371_A	445_L	0.731	0.66
211_E	214_S	0.731	0.66
210_K	214_S	0.731	0.66
437_I	447_G	0.729	0.66
451_A	454_S	0.728	0.66
31_V	107_S	0.727	0.66
346_A	383_A	0.727	0.66
354_L	445_L	0.727	0.66
77_K	310_A	0.725	0.66
319_R	424_S	0.724	0.66
117_T	386_N	0.724	0.66
79_T	94_T	0.723	0.65
333_L	442_L	0.723	0.65
458_A	462_A	0.720	0.65
410_G	415_T	0.720	0.65
12_Y	193_D	0.720	0.65
324_A	431_G	0.720	0.65
3_Y	392_A	0.719	0.65
124_F	383_A	0.719	0.65
38_G	64_L	0.717	0.65
201_T	206_Y	0.716	0.65
256_A	263_A	0.716	0.65
112_I	244_A	0.716	0.65
161_L	213_W	0.715	0.65
366_K	370_F	0.715	0.65
177_N	184_D	0.714	0.64
175_L	179_K	0.714	0.64
195_L	350_L	0.713	0.64
156_V	353_L	0.713	0.64
180_Y	194_T	0.712	0.64
76_P	381_L	0.712	0.64
19_A	23_G	0.708	0.64
333_L	338_A	0.707	0.64
128_D	217_R	0.705	0.63
110_S	379_P	0.704	0.63
369_L	373_I	0.703	0.63
191_L	275_Q	0.703	0.63
291_N	295_D	0.702	0.63
228_L	239_F	0.701	0.63
31_V	36_L	0.701	0.63
62_W	65_V	0.701	0.63
249_L	440_L	0.699	0.63
428_A	435_L	0.699	0.63
207_P	407_G	0.698	0.63
446_K	452_G	0.698	0.63
376_Q	437_I	0.696	0.62
449_G	452_G	0.694	0.62
337_Q	382_A	0.694	0.62
106_A	113_G	0.694	0.62
5_Y	15_L	0.694	0.62
367_G	446_K	0.694	0.62
380_P	387_S	0.693	0.62
180_Y	185_L	0.693	0.62
17_A	249_L	0.692	0.62
257_Y	265_Q	0.689	0.62
442_L	449_G	0.689	0.62
406_L	444_L	0.687	0.61
452_G	455_L	0.686	0.61
419_I	422_A	0.686	0.61
394_Y	429_V	0.685	0.61
20_M	123_A	0.684	0.61
152_I	157_L	0.680	0.61
257_Y	264_S	0.679	0.61
430_A	447_G	0.679	0.61
10_I	322_W	0.679	0.61
162_Q	429_V	0.678	0.60
63_L	350_L	0.677	0.60
123_A	333_L	0.675	0.60
138_L	213_W	0.675	0.60
164_F	194_T	0.675	0.60
25_G	181_S	0.675	0.60
25_G	29_S	0.674	0.60
358_P	388_I	0.669	0.59
322_W	338_A	0.669	0.59
15_L	97_N	0.668	0.59
207_P	213_W	0.667	0.59
175_L	180_Y	0.666	0.59
354_L	365_L	0.664	0.59
31_V	266_S	0.664	0.59
43_L	55_S	0.663	0.59
190_D	274_R	0.663	0.59
166_R	218_A	0.661	0.59
24_S	109_S	0.661	0.59
225_D	229_A	0.661	0.59
217_R	351_V	0.660	0.58
196_R	218_A	0.660	0.58
349_P	378_W	0.660	0.58
173_I	177_N	0.659	0.58
210_K	340_L	0.658	0.58
378_W	441_A	0.658	0.58
450_A	458_A	0.656	0.58
288_T	292_A	0.652	0.57
257_Y	272_I	0.652	0.57
406_L	410_G	0.652	0.57
273_L	380_P	0.652	0.57
37_L	357_Y	0.651	0.57
24_S	34_G	0.650	0.57
11_L	341_E	0.648	0.57
17_A	387_S	0.647	0.57
4_T	387_S	0.647	0.57
177_N	181_S	0.647	0.57
43_L	111_G	0.646	0.57
456_A	460_G	0.644	0.57
291_N	296_A	0.643	0.56
232_L	237_G	0.643	0.56
336_L	457_G	0.641	0.56
321_S	325_A	0.640	0.56
220_L	224_V	0.639	0.56
451_A	456_A	0.638	0.56
88_P	91_S	0.638	0.56
4_T	338_A	0.637	0.56
240_G	271_D	0.636	0.56
164_F	212_A	0.635	0.55
30_L	33_T	0.633	0.55
7_G	341_E	0.632	0.55
378_W	438_P	0.631	0.55
329_A	337_Q	0.631	0.55
157_L	216_L	0.630	0.55
32_A	43_L	0.630	0.55
11_L	82_I	0.630	0.55
119_A	457_G	0.630	0.55
375_L	436_S	0.626	0.54
407_G	412_T	0.626	0.54
355_S	361_G	0.624	0.54
160_E	215_G	0.623	0.54
373_I	377_L	0.623	0.54
316_A	435_L	0.623	0.54
21_I	33_T	0.621	0.54
354_L	411_L	0.620	0.54
294_N	298_A	0.618	0.54
195_L	278_L	0.618	0.54
74_F	352_L	0.618	0.54
143_L	448_G	0.616	0.53
454_S	463_A	0.616	0.53
370_F	447_G	0.616	0.53
322_W	432_Y	0.615	0.53
67_L	71_L	0.615	0.53
297_A	307_L	0.614	0.53
454_S	458_A	0.613	0.53
371_A	374_W	0.613	0.53
322_W	428_A	0.613	0.53
20_M	126_L	0.612	0.53
344_I	415_T	0.612	0.53
18_V	22_F	0.612	0.53
213_W	249_L	0.612	0.53
172_D	181_S	0.611	0.53
117_T	334_P	0.611	0.53
5_Y	113_G	0.608	0.52
103_A	341_E	0.606	0.52
323_A	349_P	0.605	0.52
361_G	447_G	0.603	0.52
244_A	247_A	0.602	0.52
269_A	273_L	0.600	0.51
339_V	388_I	0.599	0.51
155_P	159_Q	0.598	0.51
98_V	106_A	0.597	0.51
8_G	88_P	0.597	0.51
33_T	369_L	0.596	0.51
183_D	187_N	0.595	0.51
190_D	238_G	0.594	0.51
182_L	195_L	0.594	0.51
22_F	122_T	0.594	0.51
88_P	444_L	0.592	0.50
131_S	191_L	0.592	0.50
214_S	217_R	0.592	0.50
443_A	446_K	0.592	0.50
332_A	382_A	0.590	0.50
378_W	387_S	0.590	0.50
338_A	348_F	0.588	0.50
117_T	133_S	0.587	0.50
247_A	267_A	0.586	0.50
227_G	230_T	0.586	0.50
67_L	346_A	0.586	0.50
178_G	234_A	0.585	0.50
438_P	447_G	0.584	0.49
186_L	190_D	0.584	0.49
47_A	54_L	0.584	0.49
15_L	345_Y	0.583	0.49
81_T	84_D	0.582	0.49
36_L	108_L	0.581	0.49
325_A	334_P	0.580	0.49
6_G	335_M	0.580	0.49
1_E	386_N	0.579	0.49
291_N	297_A	0.578	0.49
278_L	350_L	0.577	0.49
291_N	294_N	0.575	0.48
195_L	213_W	0.575	0.48
275_Q	280_N	0.575	0.48
287_Q	411_L	0.575	0.48
40_L	112_I	0.574	0.48
113_G	337_Q	0.573	0.48
142_Q	145_M	0.573	0.48
11_L	14_V	0.573	0.48
10_I	333_L	0.573	0.48
366_K	441_A	0.572	0.48
413_L	416_A	0.571	0.48
371_A	442_L	0.570	0.48
295_D	299_D	0.570	0.48
366_K	445_L	0.570	0.48
264_S	405_N	0.563	0.47
460_G	463_A	0.562	0.47
213_W	274_R	0.561	0.47
365_L	408_L	0.557	0.46
9_W	13_N	0.556	0.46
2_I	11_L	0.556	0.46
191_L	449_G	0.556	0.46
240_G	300_A	0.555	0.46
185_L	202_V	0.555	0.46
344_I	375_L	0.555	0.46
314_A	431_G	0.554	0.46
260_L	275_Q	0.554	0.46
446_K	459_L	0.554	0.46
104_L	154_D	0.553	0.46
160_E	216_L	0.553	0.46
79_T	239_F	0.552	0.46
363_K	435_L	0.552	0.46
98_V	177_N	0.552	0.46
215_G	218_A	0.551	0.46
366_K	446_K	0.550	0.45
81_T	89_T	0.550	0.45
439_L	450_A	0.550	0.45
7_G	15_L	0.549	0.45
21_I	184_D	0.548	0.45
33_T	258_Q	0.546	0.45
36_L	353_L	0.546	0.45
351_V	355_S	0.544	0.45
273_L	309_Y	0.542	0.45
237_G	240_G	0.541	0.44
214_S	411_L	0.541	0.44
393_L	423_A	0.539	0.44
144_L	256_A	0.538	0.44
206_Y	347_L	0.537	0.44
370_F	446_K	0.537	0.44
125_S	133_S	0.537	0.44
106_A	110_S	0.537	0.44
310_A	314_A	0.533	0.43
243_D	246_A	0.532	0.43
453_S	460_G	0.532	0.43
362_L	365_L	0.532	0.43
194_T	282_L	0.532	0.43
211_E	406_L	0.531	0.43
140_G	382_A	0.530	0.43
340_L	393_L	0.529	0.43
315_E	318_Q	0.529	0.43
259_Y	262_G	0.528	0.43
161_L	277_L	0.528	0.43
231_R	240_G	0.528	0.43
453_S	461_G	0.527	0.43
382_A	385_L	0.526	0.43
274_R	443_A	0.526	0.43
175_L	184_D	0.525	0.43
223_E	247_A	0.525	0.43
63_L	76_P	0.525	0.43
77_K	83_E	0.524	0.42
126_L	355_S	0.524	0.42
138_L	454_S	0.524	0.42
30_L	425_D	0.523	0.42
188_S	284_D	0.521	0.42
434_F	437_I	0.521	0.42
38_G	49_E	0.520	0.42
110_S	380_P	0.520	0.42
48_R	67_L	0.519	0.42
206_Y	366_K	0.519	0.42
218_A	221_L	0.519	0.42
392_A	395_G	0.519	0.42
37_L	344_I	0.519	0.42
171_P	429_V	0.518	0.42
110_S	345_Y	0.517	0.42
43_L	164_F	0.517	0.42
30_L	36_L	0.517	0.42
438_P	441_A	0.516	0.41
17_A	89_T	0.516	0.41
73_L	129_L	0.516	0.41
323_A	427_L	0.516	0.41
20_M	24_S	0.515	0.41
141_R	386_N	0.514	0.41
5_Y	114_Y	0.514	0.41
68_L	207_P	0.514	0.41
451_A	463_A	0.513	0.41
14_V	345_Y	0.513	0.41
340_L	375_L	0.513	0.41
361_G	368_Y	0.513	0.41
453_S	458_A	0.512	0.41
100_L	103_A	0.512	0.41
33_T	36_L	0.512	0.41
197_S	210_K	0.512	0.41
318_Q	326_G	0.511	0.41
1_E	431_G	0.510	0.41
313_Q	320_S	0.509	0.41
14_V	32_A	0.509	0.41
154_D	263_A	0.509	0.41
177_N	180_Y	0.509	0.41
327_D	330_R	0.508	0.41
351_V	387_S	0.508	0.41
112_I	148_R	0.508	0.41
113_G	345_Y	0.507	0.40
2_I	110_S	0.507	0.40
166_R	300_A	0.507	0.40
358_P	385_L	0.506	0.40
320_S	337_Q	0.505	0.40
314_A	456_A	0.505	0.40
228_L	232_L	0.505	0.40
314_A	385_L	0.504	0.40
40_L	281_A	0.504	0.40
363_K	446_K	0.504	0.40
191_L	309_Y	0.503	0.40
113_G	377_L	0.503	0.40
11_L	333_L	0.502	0.40
376_Q	386_N	0.502	0.40
7_G	358_P	0.501	0.40
8_G	91_S	0.501	0.40
339_V	458_A	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ccdA	2	0.1649	4.1	0.972	Contact Map
2mmuA	1	0.1071	3.4	0.973	Contact Map
4c48C	1	0.0942	2.7	0.974	Contact Map
4z35A	1	0.2591	2.6	0.975	Contact Map
4u15A	2	0.2762	1.9	0.977	Contact Map
4mqsA	1	0.2719	1.8	0.977	Contact Map
4ognA	1	0.2099	1.6	0.977	Contact Map
4ldeA	1	0.2612	1.6	0.978	Contact Map
4h33A	3	0.1949	1.5	0.978	Contact Map
3v2yA	1	0.2891	1.4	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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