GREMLIN Database
DUF1631 - Protein of unknown function (DUF1631)
PFAM: PF07793 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 742 (733)
Sequences: 3178 (2596)
Seq/√Len: 95.9
META: 0.759

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
502_R546_D8.4011.00
532_G535_S5.2971.00
135_R198_N4.9161.00
441_R445_E4.6551.00
452_V456_L4.4781.00
672_E723_R3.6151.00
551_S600_H3.5621.00
527_A541_A3.5501.00
108_L112_L3.5411.00
656_D718_R3.4491.00
152_L197_L3.4141.00
531_H537_E3.3581.00
434_K459_E3.3141.00
685_L697_F3.3011.00
198_N207_L3.2721.00
434_K437_R3.1811.00
190_L194_Y3.1481.00
486_E689_S3.1311.00
516_L545_A3.0611.00
410_L438_V2.9901.00
708_M716_L2.8951.00
498_E542_L2.8751.00
502_R542_L2.8611.00
498_E502_R2.8271.00
33_D60_R2.7801.00
413_R461_E2.7411.00
730_L733_R2.7351.00
395_L446_F2.6831.00
498_E501_R2.5901.00
663_R710_R2.5821.00
441_R459_E2.5521.00
523_V527_A2.5391.00
544_T574_R2.5281.00
527_A535_S2.5241.00
673_F722_A2.4561.00
557_T560_E2.4491.00
105_D108_L2.4271.00
342_S345_L2.3881.00
207_L210_L2.3681.00
550_W567_L2.3031.00
199_Q203_E2.2871.00
120_R183_E2.2821.00
446_F450_L2.2751.00
446_F449_D2.2671.00
58_E62_K2.2541.00
576_R589_R2.2521.00
129_L154_P2.2461.00
515_F519_A2.2281.00
34_D37_F2.2191.00
716_L721_R2.2021.00
476_Q480_E2.1791.00
39_L52_Y2.1731.00
686_A698_V2.1691.00
671_F697_F2.1541.00
63_R67_E2.1451.00
40_A53_F2.1331.00
268_F272_R2.1291.00
240_P243_A2.1221.00
381_L439_V2.1171.00
37_F53_F2.1161.00
133_N150_N2.1131.00
125_C191_G2.1001.00
62_K65_A2.0951.00
110_E179_L2.0851.00
446_F452_V2.0851.00
550_W569_P2.0681.00
33_D57_R2.0581.00
37_F49_Q2.0521.00
135_R207_L2.0431.00
477_R484_G2.0271.00
563_R567_L2.0101.00
104_D107_E1.9991.00
482_A486_E1.9991.00
73_A163_E1.9871.00
494_R533_E1.9821.00
486_E687_W1.9711.00
43_A46_N1.9671.00
622_P631_P1.9501.00
110_E175_R1.9241.00
593_F600_H1.9161.00
30_D63_R1.9141.00
202_I207_L1.9021.00
53_F56_M1.8971.00
381_L432_Y1.8951.00
374_L418_A1.8921.00
441_R456_L1.8841.00
542_L546_D1.8821.00
441_R455_E1.8691.00
502_R545_A1.8651.00
378_V435_I1.8511.00
389_V407_A1.8501.00
37_F40_A1.8441.00
555_K560_E1.8421.00
410_L460_L1.8231.00
520_W578_G1.8021.00
519_A579_L1.8021.00
240_P249_G1.7961.00
454_E458_A1.7881.00
446_F453_F1.7881.00
550_W563_R1.7821.00
610_A614_A1.7811.00
407_A453_F1.7751.00
132_L201_L1.7701.00
198_N210_L1.7671.00
512_V552_V1.7671.00
37_F41_D1.7571.00
415_A730_L1.7501.00
413_R457_L1.7451.00
198_N202_I1.7421.00
58_E61_R1.7271.00
438_V460_L1.7221.00
523_V541_A1.7201.00
633_D637_E1.7191.00
616_A620_A1.7131.00
550_W555_K1.7021.00
543_A547_D1.6891.00
600_H604_L1.6671.00
634_A637_E1.6651.00
49_Q53_F1.6611.00
135_R202_I1.6601.00
391_K446_F1.6581.00
146_D149_N1.6561.00
662_A710_R1.6421.00
46_N49_Q1.6411.00
658_M718_R1.6411.00
495_A499_L1.6411.00
417_A460_L1.6331.00
217_R220_P1.6281.00
161_F186_V1.6241.00
33_D56_M1.6151.00
383_A386_Q1.6151.00
698_V702_G1.6051.00
550_W564_L1.6021.00
354_D397_P1.5991.00
13_C197_L1.5961.00
547_D567_L1.5961.00
442_I452_V1.5951.00
502_R549_L1.5941.00
198_N208_P1.5861.00
515_F592_F1.5861.00
279_R356_D1.5751.00
495_A516_L1.5711.00
627_A632_L1.5701.00
50_N54_D1.5701.00
229_A232_A1.5681.00
237_A241_A1.5591.00
551_S564_L1.5551.00
389_V399_F1.5521.00
569_P600_H1.5521.00
365_F389_V1.5291.00
200_L204_A1.5141.00
56_M60_R1.5011.00
65_A69_R1.5001.00
644_D648_L1.4961.00
472_E476_Q1.4951.00
338_L342_S1.4931.00
673_F683_A1.4921.00
665_L671_F1.4911.00
735_L738_V1.4871.00
579_L582_I1.4871.00
125_C128_E1.4871.00
238_A241_A1.4751.00
526_L530_R1.4701.00
442_I456_L1.4651.00
268_F271_L1.4651.00
658_M662_A1.4591.00
633_D639_A1.4581.00
271_L274_L1.4561.00
128_E195_A1.4521.00
641_L644_D1.4501.00
626_A629_A1.4481.00
716_L722_A1.4431.00
417_A464_L1.4421.00
33_D63_R1.4331.00
249_G252_G1.4311.00
615_L618_A1.4291.00
113_A176_L1.4231.00
632_L636_E1.4201.00
40_A43_A1.4191.00
623_A628_P1.4090.99
339_R342_S1.4080.99
43_A49_Q1.4060.99
629_A632_L1.4050.99
688_I695_Y1.4040.99
231_A234_A1.3980.99
122_E147_D1.3960.99
495_A521_A1.3870.99
639_A643_A1.3860.99
544_T578_G1.3840.99
12_Q200_L1.3830.99
481_A484_G1.3790.99
272_R275_L1.3660.99
436_E440_Q1.3650.99
699_N703_Q1.3620.99
135_R201_L1.3550.99
409_R461_E1.3510.99
434_K463_F1.3500.99
636_E642_G1.3500.99
522_D687_W1.3470.99
498_E538_W1.3460.99
616_A619_A1.3460.99
391_K395_L1.3370.99
473_L476_Q1.3370.99
416_E468_R1.3340.99
381_L435_I1.3320.99
624_P634_A1.3320.99
336_N342_S1.3320.99
658_M717_L1.3230.99
240_P245_A1.3230.99
634_A638_E1.3190.99
335_L338_L1.3170.99
484_G487_R1.3170.99
597_E600_H1.3080.99
268_F274_L1.3070.99
132_L139_L1.3020.99
392_V450_L1.3010.99
145_L149_N1.3010.99
365_F388_P1.2990.99
309_S312_Q1.2950.99
339_R343_G1.2930.99
242_A247_A1.2910.99
561_R565_L1.2860.99
547_D574_R1.2850.99
76_E80_R1.2800.99
335_L339_R1.2770.99
457_L460_L1.2760.99
549_L552_V1.2720.99
551_S569_P1.2670.99
484_G488_L1.2650.99
438_V456_L1.2630.99
545_A549_L1.2630.99
239_A242_A1.2530.99
233_G237_A1.2510.99
540_A574_R1.2510.99
483_E487_R1.2420.99
198_N206_V1.2410.99
625_A628_P1.2310.99
496_A521_A1.2310.99
248_A253_A1.2260.99
268_F275_L1.2220.98
267_L274_L1.2200.98
34_D38_E1.2190.98
640_L643_A1.2170.98
630_A641_L1.2160.98
643_A648_L1.2140.98
326_A342_S1.2090.98
182_F186_V1.2090.98
40_A49_Q1.2080.98
508_L549_L1.2040.98
580_A589_R1.2000.98
630_A633_D1.1980.98
359_D687_W1.1970.98
622_P626_A1.1940.98
695_Y710_R1.1870.98
68_R72_Q1.1860.98
341_L345_L1.1810.98
381_L436_E1.1790.98
336_N343_G1.1770.98
54_D57_R1.1770.98
121_A186_V1.1750.98
160_A164_A1.1690.98
13_C201_L1.1650.98
250_A253_A1.1650.98
308_L387_I1.1620.98
330_L333_Q1.1610.98
672_E725_L1.1490.98
618_A621_L1.1470.98
345_L348_A1.1440.98
25_L29_F1.1430.98
412_N456_L1.1400.98
66_I165_L1.1400.98
671_F724_L1.1390.98
449_D453_F1.1390.98
429_D432_Y1.1360.98
244_A261_G1.1350.98
613_A616_A1.1350.98
385_L390_L1.1340.98
371_D733_R1.1330.98
616_A621_L1.1330.98
488_L525_A1.1320.98
494_R528_L1.1320.98
671_F683_A1.1300.97
637_E640_L1.1290.97
334_L342_S1.1270.97
37_F60_R1.1190.97
271_L275_L1.1180.97
417_A420_G1.1160.97
369_L383_A1.1130.97
366_D369_L1.1120.97
568_L600_H1.1090.97
96_S99_E1.1060.97
624_P630_A1.1030.97
254_A257_A1.0970.97
546_D549_L1.0970.97
112_L359_D1.0970.97
251_A254_A1.0950.97
19_E23_A1.0930.97
110_E162_R1.0920.97
34_D57_R1.0910.97
337_Q340_Q1.0910.97
456_L459_E1.0890.97
80_R85_R1.0880.97
135_R210_L1.0870.97
267_L271_L1.0830.97
698_V704_K1.0820.97
617_A621_L1.0810.97
153_G156_V1.0810.97
685_L695_Y1.0790.97
236_A243_A1.0790.97
622_P628_P1.0790.97
360_L476_Q1.0780.97
301_S309_S1.0770.97
465_A468_R1.0700.96
624_P631_P1.0700.96
145_L150_N1.0700.96
617_A620_A1.0690.96
626_A633_D1.0660.96
359_D486_E1.0630.96
240_P246_A1.0620.96
122_E153_G1.0620.96
709_S712_E1.0590.96
57_R61_R1.0520.96
629_A637_E1.0510.96
626_A630_A1.0490.96
486_E490_L1.0480.96
626_A631_P1.0440.96
48_E359_D1.0430.96
236_A240_P1.0430.96
378_V421_W1.0390.96
631_P635_A1.0380.96
729_P733_R1.0360.96
646_S649_E1.0360.96
269_A272_R1.0350.96
628_P636_E1.0340.96
640_L645_A1.0340.96
644_D647_P1.0330.96
267_L272_R1.0320.96
34_D61_R1.0310.96
641_L645_A1.0300.96
131_A134_Q1.0300.96
399_F731_F1.0250.96
100_L103_V1.0250.96
672_E682_R1.0230.95
55_A174_V1.0220.95
519_A584_Y1.0200.95
499_L503_L1.0190.95
34_D56_M1.0170.95
138_V207_L1.0170.95
247_A250_A1.0160.95
376_D379_K1.0140.95
612_A616_A1.0120.95
614_A620_A1.0030.95
230_A233_G1.0010.95
688_I692_T1.0000.95
275_L278_R0.9990.95
337_Q342_S0.9970.95
271_L278_R0.9940.95
437_R459_E0.9940.95
387_I446_F0.9930.95
268_F397_P0.9920.95
331_R335_L0.9880.95
683_A689_S0.9870.94
400_F408_R0.9840.94
729_P732_D0.9840.94
391_K453_F0.9820.94
500_R517_E0.9820.94
622_P627_A0.9810.94
252_G261_G0.9800.94
484_G526_L0.9790.94
291_A294_G0.9780.94
379_K499_L0.9760.94
351_G354_D0.9740.94
387_I453_F0.9730.94
637_E642_G0.9730.94
712_E716_L0.9730.94
392_V453_F0.9710.94
223_A232_A0.9700.94
60_R63_R0.9680.94
449_D452_V0.9680.94
696_L700_R0.9670.94
659_L714_A0.9670.94
696_L702_G0.9630.94
687_W691_R0.9610.94
334_L337_Q0.9600.94
268_F279_R0.9600.94
609_A612_A0.9600.94
29_F63_R0.9590.94
312_Q446_F0.9580.94
240_P244_A0.9540.93
630_A635_A0.9530.93
561_R569_P0.9510.93
633_D642_G0.9480.93
77_A156_V0.9470.93
246_A249_G0.9470.93
73_A160_A0.9460.93
70_F157_L0.9430.93
105_D112_L0.9420.93
624_P639_A0.9410.93
658_M661_R0.9400.93
121_A190_L0.9380.93
270_A273_Q0.9360.93
34_D60_R0.9340.93
124_R191_G0.9340.93
510_E514_D0.9310.93
535_S538_W0.9310.93
519_A523_V0.9280.92
308_L312_Q0.9250.92
625_A629_A0.9210.92
460_L468_R0.9210.92
229_A233_G0.9200.92
635_A638_E0.9200.92
393_A734_A0.9180.92
223_A229_A0.9170.92
508_L516_L0.9170.92
495_A525_A0.9140.92
198_N201_L0.9140.92
637_E644_D0.9120.92
592_F600_H0.9120.92
667_V688_I0.9120.92
578_G582_I0.9090.92
627_A631_P0.9080.92
552_V600_H0.9050.92
14_R75_R0.9050.92
241_A250_A0.9040.91
336_N339_R0.9010.91
253_A259_A0.9010.91
687_W696_L0.8990.91
338_L345_L0.8990.91
632_L639_A0.8970.91
421_W432_Y0.8960.91
421_W429_D0.8960.91
687_W731_F0.8930.91
37_F56_M0.8930.91
686_A736_E0.8920.91
235_G238_A0.8910.91
560_E563_R0.8910.91
242_A245_A0.8910.91
272_R276_A0.8910.91
672_E680_W0.8900.91
234_A237_A0.8890.91
611_I616_A0.8890.91
555_K561_R0.8880.91
338_L343_G0.8870.91
632_L635_A0.8870.91
137_A145_L0.8870.91
48_E173_E0.8870.91
158_C183_E0.8870.91
645_A648_L0.8860.91
686_A690_P0.8850.91
527_A538_W0.8830.90
514_D518_Q0.8810.90
457_L461_E0.8800.90
21_L24_L0.8800.90
229_A234_A0.8790.90
477_R529_L0.8770.90
62_K70_F0.8760.90
413_R464_L0.8750.90
150_N153_G0.8750.90
494_R498_E0.8720.90
523_V582_I0.8720.90
636_E639_A0.8720.90
20_R24_L0.8700.90
33_D37_F0.8700.90
611_I614_A0.8700.90
181_L185_Y0.8700.90
51_L55_A0.8700.90
161_F182_F0.8690.90
687_W690_P0.8690.90
253_A257_A0.8670.90
624_P629_A0.8660.90
623_A629_A0.8660.90
242_A250_A0.8640.90
575_L593_F0.8640.90
379_K387_I0.8630.89
635_A639_A0.8610.89
633_D641_L0.8610.89
642_G645_A0.8600.89
241_A252_G0.8580.89
551_S604_L0.8560.89
216_R220_P0.8550.89
631_P634_A0.8540.89
248_A255_G0.8530.89
682_R735_L0.8530.89
632_L637_E0.8510.89
69_R73_A0.8490.89
20_R23_A0.8490.89
572_L600_H0.8480.89
536_E540_A0.8480.89
52_Y56_M0.8470.89
506_R553_Q0.8470.89
532_G538_W0.8460.89
158_C179_L0.8460.89
435_I439_V0.8400.88
253_A256_A0.8390.88
362_A386_Q0.8380.88
233_G238_A0.8370.88
627_A637_E0.8360.88
109_E112_L0.8340.88
631_P637_E0.8320.88
231_A235_G0.8310.88
614_A617_A0.8310.88
350_L358_I0.8290.88
304_L307_A0.8290.88
412_N729_P0.8280.87
237_A242_A0.8270.87
230_A234_A0.8260.87
105_D109_E0.8250.87
202_I210_L0.8250.87
499_L545_A0.8230.87
441_R452_V0.8220.87
121_A187_L0.8200.87
662_A717_L0.8190.87
162_R179_L0.8190.87
639_A642_G0.8180.87
630_A637_E0.8180.87
550_W560_E0.8180.87
626_A634_A0.8170.87
611_I615_L0.8170.87
482_A522_D0.8130.86
536_E539_R0.8130.86
643_A647_P0.8130.86
11_E14_R0.8120.86
232_A236_A0.8120.86
61_R65_A0.8120.86
121_A125_C0.8120.86
248_A254_A0.8110.86
384_R387_I0.8110.86
14_R79_A0.8100.86
177_I181_L0.8100.86
646_S650_V0.8100.86
40_A52_Y0.8090.86
49_Q56_M0.8090.86
207_L211_K0.8080.86
218_A221_R0.8070.86
647_P650_V0.8060.86
412_N696_L0.8060.86
642_G646_S0.8060.86
202_I208_P0.8060.86
641_L648_L0.8060.86
561_R604_L0.8060.86
284_A287_G0.8040.86
250_A254_A0.8030.86
484_G530_R0.8020.86
662_A665_L0.7990.86
687_W710_R0.7980.85
385_L442_I0.7970.85
304_L360_L0.7960.85
639_A645_A0.7960.85
692_T695_Y0.7960.85
624_P628_P0.7960.85
682_R725_L0.7940.85
434_K438_V0.7930.85
411_L453_F0.7930.85
305_L311_L0.7930.85
342_S346_K0.7930.85
193_L197_L0.7930.85
329_D333_Q0.7910.85
641_L647_P0.7900.85
516_L549_L0.7890.85
487_R524_L0.7880.85
396_D405_H0.7870.85
135_R206_V0.7860.85
254_A266_A0.7860.85
234_A238_A0.7850.85
473_L477_R0.7850.85
245_A250_A0.7840.84
299_L302_P0.7840.84
216_R219_A0.7830.84
569_P573_K0.7830.84
389_V392_V0.7830.84
544_T593_F0.7800.84
624_P636_E0.7770.84
666_Q669_T0.7770.84
379_K600_H0.7760.84
487_R529_L0.7760.84
417_A421_W0.7750.84
245_A251_A0.7750.84
491_A495_A0.7740.84
400_F575_L0.7740.84
459_E466_E0.7740.84
394_L414_L0.7730.84
502_R553_Q0.7710.83
639_A648_L0.7710.83
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301_S304_L0.7690.83
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234_A266_A0.7670.83
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331_R342_S0.7670.83
262_A265_Q0.7670.83
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230_A236_A0.7660.83
644_D650_V0.7650.83
337_Q341_L0.7640.83
487_R522_D0.7640.83
523_V579_L0.7640.83
246_A252_G0.7640.83
268_F273_Q0.7610.83
579_L585_D0.7600.83
580_A586_P0.7600.83
381_L421_W0.7590.82
713_L733_R0.7590.82
107_E111_S0.7590.82
368_I730_L0.7570.82
625_A632_L0.7570.82
655_D715_R0.7550.82
579_L593_F0.7540.82
275_L279_R0.7530.82
297_P302_P0.7520.82
308_L311_L0.7510.82
713_L717_L0.7510.82
503_L508_L0.7500.82
638_E642_G0.7500.82
634_A639_A0.7480.82
247_A262_A0.7470.81
236_A239_A0.7450.81
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9_L12_Q0.7410.81
267_L270_A0.7400.81
249_G257_A0.7400.81
244_A252_G0.7380.81
467_E700_R0.7380.81
297_P300_S0.7370.81
474_A478_A0.7370.81
638_E641_L0.7370.81
330_L342_S0.7370.81
297_P303_E0.7360.81
479_V486_E0.7360.81
565_L572_L0.7350.80
246_A250_A0.7350.80
634_A643_A0.7330.80
633_D636_E0.7320.80
241_A248_A0.7320.80
604_L667_V0.7290.80
508_L513_R0.7290.80
331_R338_L0.7280.80
275_L579_L0.7280.80
375_P386_Q0.7270.80
51_L54_D0.7270.80
492_R522_D0.7270.80
633_D638_E0.7260.80
41_D53_F0.7250.80
614_A618_A0.7250.80
634_A640_L0.7240.79
196_E199_Q0.7230.79
70_F79_A0.7220.79
240_P248_A0.7220.79
267_L277_G0.7190.79
237_A252_G0.7180.79
392_V446_F0.7170.79
670_W699_N0.7170.79
643_A646_S0.7160.79
239_A247_A0.7150.79
460_L463_F0.7140.78
105_D412_N0.7120.78
694_R702_G0.7120.78
629_A634_A0.7110.78
232_A235_G0.7100.78
334_L339_R0.7080.78
270_A274_L0.7080.78
630_A639_A0.7070.78
631_P636_E0.7060.78
251_A257_A0.7050.78
331_R359_D0.7050.78
418_A431_L0.7050.78
476_Q583_G0.7040.77
697_F707_E0.7040.77
412_N415_A0.7040.77
648_L651_V0.7030.77
53_F57_R0.7030.77
628_P631_P0.7030.77
357_T389_V0.7020.77
261_G264_A0.7020.77
638_E644_D0.7010.77
656_D660_A0.7010.77
636_E643_A0.7010.77
219_A223_A0.7000.77
690_P696_L0.6990.77
77_A91_A0.6970.77
27_A30_D0.6960.77
615_L621_L0.6950.77
336_N341_L0.6950.77
506_R509_P0.6950.77
392_V407_A0.6940.76
230_A237_A0.6940.76
585_D588_E0.6940.76
638_E643_A0.6940.76
399_F407_A0.6930.76
410_L417_A0.6930.76
697_F702_G0.6910.76
623_A626_A0.6910.76
565_L569_P0.6890.76
484_G529_L0.6890.76
629_A635_A0.6890.76
286_A292_G0.6890.76
445_E452_V0.6880.76
38_E41_D0.6880.76
379_K383_A0.6870.76
689_S696_L0.6860.76
299_L304_L0.6860.76
573_K577_E0.6860.76
696_L704_K0.6850.76
28_L31_R0.6850.76
485_R492_R0.6850.76
176_L180_K0.6840.75
236_A242_A0.6840.75
384_R440_Q0.6840.75
614_A621_L0.6830.75
168_L545_A0.6810.75
694_R707_E0.6790.75
281_G285_A0.6790.75
640_L644_D0.6790.75
368_I385_L0.6790.75
243_A251_A0.6760.75
515_F548_L0.6760.75
471_A475_E0.6750.74
699_N705_V0.6740.74
478_A485_R0.6740.74
689_S692_T0.6730.74
267_L275_L0.6730.74
117_M176_L0.6710.74
691_R694_R0.6710.74
688_I693_G0.6710.74
568_L589_R0.6700.74
699_N702_G0.6680.74
731_F735_L0.6680.74
128_E191_G0.6680.74
683_A687_W0.6680.74
528_L533_E0.6660.74
15_D19_E0.6660.74
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421_W431_L0.6650.73
655_D731_F0.6650.73
229_A253_A0.6650.73
236_A245_A0.6650.73
37_F43_A0.6640.73
480_E483_E0.6640.73
56_M184_R0.6630.73
473_L481_A0.6630.73
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568_L601_A0.6630.73
368_I411_L0.6620.73
655_D663_R0.6600.73
325_A328_A0.6590.73
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139_L201_L0.6580.73
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132_L198_N0.6550.72
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22_E71_L0.6520.72
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439_V443_L0.6510.72
386_Q389_V0.6500.72
56_M61_R0.6490.72
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309_S391_K0.6490.72
550_W561_R0.6470.71
630_A638_E0.6470.71
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287_G291_A0.6460.71
662_A714_A0.6450.71
674_D680_W0.6450.71
357_T365_F0.6450.71
541_A684_K0.6440.71
469_R477_R0.6430.71
28_L186_V0.6420.71
531_H535_S0.6420.71
116_R119_S0.6410.71
405_H408_R0.6410.71
673_F716_L0.6410.71
72_Q80_R0.6400.71
549_L662_A0.6400.71
113_A180_K0.6400.71
231_A236_A0.6390.70
728_E736_E0.6380.70
358_I363_M0.6380.70
486_E691_R0.6370.70
357_T412_N0.6370.70
40_A55_A0.6370.70
421_W682_R0.6370.70
475_E698_V0.6370.70
364_L738_V0.6360.70
690_P693_G0.6350.70
29_F161_F0.6340.70
118_A524_L0.6340.70
61_R64_A0.6330.70
243_A248_A0.6330.70
632_L640_L0.6330.70
286_A289_A0.6330.70
251_A259_A0.6320.70
306_S310_R0.6320.70
246_A251_A0.6310.69
387_I391_K0.6310.69
72_Q76_E0.6310.69
299_L303_E0.6300.69
40_A364_L0.6300.69
299_L311_L0.6280.69
561_R601_A0.6280.69
280_G285_A0.6270.69
636_E641_L0.6270.69
303_E310_R0.6270.69
270_A275_L0.6270.69
579_L589_R0.6260.69
520_W523_V0.6250.69
300_S303_E0.6250.69
686_A691_R0.6250.69
35_A42_K0.6230.68
257_A261_G0.6230.68
371_D374_L0.6220.68
26_Q67_E0.6220.68
52_Y63_R0.6210.68
570_G573_K0.6210.68
523_V593_F0.6200.68
239_A244_A0.6200.68
190_L512_V0.6200.68
388_P442_I0.6200.68
367_F443_L0.6190.68
627_A633_D0.6180.68
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438_V442_I0.6170.68
10_L15_D0.6160.68
715_R719_A0.6150.68
628_P638_E0.6150.68
652_S655_D0.6140.67
16_L200_L0.6140.67
494_R501_R0.6130.67
287_G294_G0.6130.67
197_L201_L0.6130.67
222_A232_A0.6120.67
33_D53_F0.6100.67
669_T724_L0.6100.67
388_P524_L0.6100.67
589_R601_A0.6090.67
612_A615_L0.6090.67
628_P633_D0.6090.67
579_L584_Y0.6090.67
567_L570_G0.6070.66
69_R160_A0.6050.66
42_K45_S0.6040.66
243_A252_G0.6040.66
396_D407_A0.6040.66
441_R446_F0.6030.66
137_A149_N0.6020.66
475_E684_K0.6020.66
238_A247_A0.6020.66
559_E562_A0.6000.66
288_A624_P0.6000.66
548_L578_G0.5990.65
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331_R339_R0.5980.65
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266_A269_A0.5900.64
135_R139_L0.5900.64
563_R566_A0.5900.64
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385_L520_W0.5860.64
637_E645_A0.5860.64
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632_L644_D0.5850.64
513_R517_E0.5850.64
523_V581_S0.5850.64
638_E645_A0.5840.64
244_A248_A0.5840.64
703_Q725_L0.5830.63
524_L538_W0.5830.63
691_R696_L0.5820.63
28_L32_A0.5810.63
387_I417_A0.5810.63
312_Q452_V0.5810.63
713_L722_A0.5800.63
40_A46_N0.5790.63
206_V234_A0.5790.63
232_A253_A0.5790.63
183_E187_L0.5780.63
543_A546_D0.5780.63
157_L193_L0.5780.63
492_R505_G0.5780.63
623_A627_A0.5780.63
259_A264_A0.5780.63
511_F595_E0.5770.63
366_D403_K0.5770.63
622_P630_A0.5770.63
416_E523_V0.5770.63
70_F164_A0.5770.63
694_R712_E0.5770.63
134_Q137_A0.5770.63
364_L400_F0.5750.62
593_F703_Q0.5750.62
57_R180_K0.5740.62
565_L604_L0.5730.62
176_L693_G0.5720.62
657_A660_A0.5720.62
361_V389_V0.5720.62
180_K183_E0.5720.62
244_A254_A0.5720.62
640_L646_S0.5720.62
242_A637_E0.5700.62
234_A239_A0.5690.62
247_A251_A0.5690.62
517_E521_A0.5690.62
637_E646_S0.5680.61
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343_G347_A0.5670.61
587_E590_D0.5670.61
499_L521_A0.5660.61
282_A288_A0.5660.61
110_E180_K0.5650.61
457_L682_R0.5640.61
8_A12_Q0.5640.61
492_R696_L0.5630.61
290_G293_A0.5630.61
435_I463_F0.5620.61
26_Q30_D0.5610.60
327_A378_V0.5600.60
672_E732_D0.5600.60
660_A663_R0.5590.60
23_A26_Q0.5590.60
66_I175_R0.5580.60
251_A256_A0.5580.60
198_N209_E0.5570.60
132_L385_L0.5570.60
711_E715_R0.5570.60
248_A651_V0.5570.60
551_S571_L0.5560.60
112_L486_E0.5540.59
459_E462_A0.5540.59
431_L532_G0.5540.59
343_G346_K0.5540.59
378_V414_L0.5540.59
145_L360_L0.5530.59
57_R60_R0.5530.59
576_R593_F0.5520.59
631_P650_V0.5520.59
301_S311_L0.5510.59
696_L707_E0.5500.59
690_P711_E0.5500.59
473_L484_G0.5500.59
381_L417_A0.5500.59
643_A649_E0.5490.59
263_G266_A0.5480.59
252_G260_A0.5470.59
458_A462_A0.5470.59
451_A549_L0.5460.58
251_A255_G0.5460.58
301_S310_R0.5460.58
251_A629_A0.5460.58
360_L401_S0.5460.58
363_M417_A0.5450.58
234_A240_P0.5450.58
415_A551_S0.5440.58
366_D410_L0.5430.58
75_R79_A0.5430.58
365_F520_W0.5430.58
515_F707_E0.5430.58
91_A95_A0.5430.58
460_L683_A0.5420.58
81_L153_G0.5410.58
368_I386_Q0.5410.58
615_L620_A0.5410.58
240_P250_A0.5400.58
124_R157_L0.5390.57
242_A252_G0.5390.57
27_A59_L0.5390.57
87_A90_A0.5380.57
655_D661_R0.5380.57
597_E601_A0.5370.57
676_D721_R0.5370.57
32_A181_L0.5370.57
242_A249_G0.5360.57
285_A288_A0.5360.57
652_S656_D0.5360.57
38_E42_K0.5360.57
656_D662_A0.5350.57
240_P258_A0.5350.57
435_I460_L0.5350.57
336_N346_K0.5340.57
257_A265_Q0.5340.57
488_L492_R0.5340.57
525_A583_G0.5330.57
434_K460_L0.5320.56
389_V452_V0.5320.56
550_W600_H0.5320.56
249_G254_A0.5320.56
136_L139_L0.5310.56
244_A247_A0.5310.56
197_L433_A0.5310.56
178_L365_F0.5310.56
273_Q279_R0.5300.56
258_A265_Q0.5300.56
238_A257_A0.5300.56
379_K420_G0.5300.56
622_P625_A0.5290.56
243_A246_A0.5280.56
635_A644_D0.5280.56
486_E690_P0.5270.56
320_A323_A0.5260.56
296_A299_L0.5250.55
49_Q66_I0.5240.55
519_A582_I0.5240.55
244_A255_G0.5240.55
217_R222_A0.5230.55
305_L309_S0.5220.55
575_L600_H0.5210.55
474_A477_R0.5210.55
232_A250_A0.5200.55
629_A638_E0.5190.55
24_L125_C0.5190.55
390_L516_L0.5190.55
69_R167_A0.5190.55
281_G284_A0.5190.55
359_D399_F0.5180.54
272_R279_R0.5180.54
525_A687_W0.5170.54
321_A324_A0.5160.54
179_L698_V0.5160.54
286_A295_G0.5160.54
112_L734_A0.5160.54
694_R731_F0.5160.54
715_R718_R0.5150.54
101_S104_D0.5150.54
243_A250_A0.5140.54
407_A417_A0.5140.54
169_G700_R0.5130.54
677_D721_R0.5120.54
676_D679_R0.5110.54
299_L307_A0.5100.53
28_L117_M0.5100.53
233_G242_A0.5100.53
108_L116_R0.5090.53
134_Q382_I0.5090.53
689_S710_R0.5090.53
208_P713_L0.5080.53
641_L646_S0.5080.53
176_L183_E0.5080.53
414_L418_A0.5070.53
253_A258_A0.5070.53
15_D21_L0.5070.53
63_R110_E0.5070.53
220_P223_A0.5070.53
21_L27_A0.5070.53
459_E516_L0.5070.53
637_E641_L0.5070.53
241_A289_A0.5070.53
103_V108_L0.5060.53
475_E483_E0.5060.53
262_A266_A0.5050.53
152_L407_A0.5050.53
134_Q209_E0.5050.53
640_L647_P0.5040.53
711_E718_R0.5040.53
468_R472_E0.5030.52
358_I390_L0.5030.52
301_S307_A0.5030.52
705_V708_M0.5020.52
255_G258_A0.5020.52
453_F456_L0.5020.52
86_P89_A0.5010.52
246_A253_A0.5010.52
461_E464_L0.5010.52
331_R334_L0.5010.52
50_N53_F0.5010.52
32_A59_L0.5010.52
629_A639_A0.5000.52
307_A312_Q0.5000.52
37_F63_R0.5000.52
479_V566_A0.5000.52
312_Q453_F0.5000.52
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3wctD 1 0.1819 18.3 0.979 Contact Map
2wy4A 1 0.1779 16.7 0.98 Contact Map
2hq7A 3 0.124 14.6 0.98 Contact Map
1x9fA 1 0.1833 14.3 0.98 Contact Map
4anjA 1 0.0903 13.8 0.98 Contact Map
3wctC 1 0.1873 12.2 0.981 Contact Map
4e9mA 2 0.1159 11.6 0.981 Contact Map
1c7cA 1 0.2345 11.4 0.981 Contact Map
2qeaA 5 0.1213 11.1 0.981 Contact Map
3tm9A 2 0.1887 10.8 0.981 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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