GREMLIN Database
FeoB_C - Ferrous iron transport protein B C terminus
PFAM: PF07664 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 53 (52)
Sequences: 41782 (19779)
Seq/√Len: 2742.8
META: 0.933

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_L21_R3.9971.00
42_T45_N3.0271.00
44_R48_L2.2021.00
45_N48_L2.1331.00
3_G7_L2.1291.00
17_L20_K2.0621.00
5_Y9_I1.8371.00
15_V19_L1.7361.00
43_L47_L1.6771.00
49_K53_R1.6451.00
8_G12_A1.6061.00
48_L52_E1.5281.00
47_L50_T1.5071.00
46_V50_T1.5041.00
9_I13_L1.4101.00
2_F6_L1.3121.00
49_K52_E1.2971.00
12_A16_A1.2841.00
47_L51_W1.1971.00
40_L43_L1.1301.00
12_A15_V1.0881.00
14_L17_L1.0881.00
45_N49_K1.0871.00
11_V14_L1.0741.00
19_L24_L0.9791.00
5_Y14_L0.9791.00
11_V15_V0.9301.00
10_V14_L0.9281.00
7_L10_V0.9171.00
4_L8_G0.8851.00
35_L38_Y0.8841.00
4_L7_L0.8741.00
6_L10_V0.8231.00
12_A32_V0.8151.00
23_T26_G0.8121.00
25_K28_P0.8111.00
14_L18_L0.8071.00
8_G11_V0.7961.00
5_Y11_V0.7901.00
4_L11_V0.7891.00
43_L46_V0.7791.00
7_L11_V0.7751.00
5_Y8_G0.7671.00
18_L36_P0.7601.00
24_L29_S0.7431.00
44_R47_L0.7381.00
19_L23_T0.7321.00
24_L27_E0.7251.00
1_L16_A0.7241.00
10_V13_L0.7161.00
3_G6_L0.6961.00
18_L21_R0.6871.00
15_V31_F0.6861.00
40_L44_R0.6801.00
9_I12_A0.6261.00
6_L9_I0.6191.00
34_E37_P0.6161.00
1_L11_V0.6121.00
30_P33_M0.6121.00
30_P37_P0.5841.00
37_P40_L0.5821.00
42_T46_V0.5781.00
38_Y52_E0.5741.00
15_V18_L0.5631.00
10_V21_R0.5601.00
39_R46_V0.5581.00
16_A20_K0.5561.00
21_R25_K0.5481.00
46_V49_K0.5461.00
38_Y43_L0.5421.00
13_L37_P0.5401.00
1_L9_I0.5301.00
8_G38_Y0.5221.00
16_A19_L0.5221.00
26_G33_M0.5161.00
5_Y12_A0.5061.00
39_R53_R0.5041.00
36_P51_W0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ww8A 1 0 4.1 0.851 Contact Map
3effK 4 0.9623 2.9 0.862 Contact Map
3j8eG 3 0.8868 2.8 0.864 Contact Map
1gaxA 1 0.3962 2.7 0.864 Contact Map
4qmfD 1 0.4906 2.2 0.87 Contact Map
2m8rA 1 0.3774 2.2 0.87 Contact Map
2k1eA 3 0.5283 2.1 0.872 Contact Map
4ogqF 1 0.4717 2.1 0.872 Contact Map
3fymA 1 0 1.9 0.874 Contact Map
3nt8A 1 0.6604 1.8 0.876 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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