GREMLIN Database
BatA - Aerotolerance regulator N-terminal
PFAM: PF07584 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 77 (75)
Sequences: 71102 (45095)
Seq/√Len: 5207.1
META: 0.971

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_L11_L2.7521.00
14_L17_P2.4261.00
6_N9_F2.3591.00
22_L26_L2.3091.00
10_L75_A2.1621.00
11_L14_L2.1541.00
21_L25_L2.1241.00
35_F41_L2.1071.00
57_H61_L1.9881.00
5_L76_R1.9041.00
9_F12_L1.7531.00
12_L71_I1.7531.00
20_I24_L1.7481.00
13_L68_A1.6951.00
60_L64_L1.4701.00
59_L63_R1.4501.00
16_L64_L1.3961.00
14_L18_L1.3671.00
16_L68_A1.3421.00
9_F74_L1.3211.00
64_L68_A1.3021.00
37_S40_L1.2641.00
4_F75_A1.2611.00
21_L24_L1.2471.00
45_P48_R1.2451.00
28_R32_R1.1841.00
9_F71_I1.1791.00
23_H27_R1.1751.00
35_F38_L1.1641.00
58_L61_L1.1621.00
35_F40_L1.0831.00
63_R67_L1.0651.00
6_N76_R1.0551.00
11_L15_L1.0521.00
67_L71_I1.0491.00
39_R42_R1.0461.00
68_A72_L1.0361.00
4_F10_L1.0341.00
45_P49_R1.0341.00
63_R66_A1.0211.00
69_L73_A1.0171.00
8_L12_L1.0121.00
54_L57_H1.0021.00
57_H60_L0.9811.00
30_R33_V0.9711.00
47_R50_R0.9611.00
61_L65_L0.9571.00
3_S8_L0.9541.00
26_L30_R0.9491.00
13_L16_L0.9411.00
7_P11_L0.9361.00
39_R43_R0.9001.00
50_R54_L0.8881.00
56_R60_L0.8771.00
26_L29_R0.8541.00
13_L17_P0.8461.00
5_L8_L0.8421.00
10_L72_L0.8251.00
20_I64_L0.8251.00
60_L63_R0.8141.00
27_R33_V0.8071.00
56_R59_L0.8051.00
48_R55_R0.7991.00
23_H26_L0.7831.00
24_L28_R0.7831.00
28_R31_R0.7821.00
15_L18_L0.7691.00
36_S41_L0.7501.00
38_L42_R0.7381.00
62_L66_A0.7371.00
42_R45_P0.7211.00
66_A70_L0.7201.00
20_I67_L0.7161.00
54_L58_L0.7151.00
5_L9_F0.6971.00
10_L13_L0.6971.00
29_R33_V0.6931.00
27_R31_R0.6921.00
15_L19_P0.6821.00
44_A48_R0.6811.00
40_L43_R0.6781.00
27_R32_R0.6751.00
16_L71_I0.6681.00
56_R61_L0.6511.00
13_L71_I0.6381.00
63_R70_L0.6351.00
42_R46_P0.6321.00
63_R69_L0.6311.00
65_L69_L0.6181.00
37_S41_L0.6101.00
26_L33_V0.6091.00
15_L67_L0.6051.00
29_R32_R0.6001.00
48_R52_R0.5971.00
40_L44_A0.5951.00
14_L71_I0.5911.00
3_S6_N0.5891.00
26_L52_R0.5841.00
15_L71_I0.5781.00
61_L64_L0.5661.00
30_R51_R0.5661.00
27_R30_R0.5511.00
24_L27_R0.5501.00
36_S39_R0.5331.00
19_P23_H0.5281.00
51_R55_R0.5231.00
38_L41_L0.5181.00
23_H33_V0.5161.00
65_L68_A0.5041.00
71_I75_A0.5031.00
25_L29_R0.5011.00
49_R55_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wswA 3 0.8831 14 0.817 Contact Map
3mk7C 2 0.9481 6.1 0.844 Contact Map
4r2fA 1 0 3.7 0.861 Contact Map
2p4eP 2 0 3.6 0.861 Contact Map
4c7rA 3 0.8701 3.4 0.863 Contact Map
3l1lA 2 0.5065 3.3 0.864 Contact Map
3owqA 1 0 3.1 0.866 Contact Map
1yewA 3 0.9351 3.1 0.866 Contact Map
3giaA 1 0.5455 3 0.867 Contact Map
4i0uA 4 0.3766 3 0.867 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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