GREMLIN Database
FlbT - Flagellar protein FlbT
PFAM: PF07378 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 125 (125)
Sequences: 4203 (2453)
Seq/√Len: 219.4
META: 0.891

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
48_D52_R4.9211.00
51_A82_L3.3361.00
54_I82_L2.8801.00
52_R122_E2.7591.00
106_R109_K2.5771.00
19_T30_E2.3691.00
101_H106_R2.1631.00
57_A78_L2.1601.00
78_L81_E2.1551.00
97_E113_A2.1511.00
100_N104_A2.0731.00
99_S103_L2.0381.00
83_L96_D1.9711.00
64_D67_D1.8491.00
72_H76_F1.8021.00
82_L91_A1.7791.00
4_E24_R1.7271.00
76_F99_S1.6961.00
43_T46_E1.6851.00
102_V110_A1.6361.00
101_H113_A1.6041.00
101_H109_K1.5911.00
73_D77_R1.5861.00
91_A120_Y1.5741.00
50_P53_R1.5661.00
13_I18_I1.5601.00
14_N34_P1.5501.00
77_R81_E1.5421.00
29_I35_I1.5041.00
53_R81_E1.4941.00
73_D76_F1.4741.00
75_Y102_V1.4041.00
67_D70_E1.4041.00
98_I114_A1.3981.00
113_A116_K1.3671.00
70_E73_D1.3611.00
65_P68_P1.3521.00
13_I29_I1.3511.00
64_D71_Y1.3511.00
61_M75_Y1.3271.00
19_T28_L1.3101.00
75_Y99_S1.3051.00
51_A91_A1.2951.00
16_A33_A1.2741.00
44_P56_F1.2571.00
76_F103_L1.2551.00
21_G25_T1.2391.00
75_Y79_V1.2021.00
52_R118_I1.1951.00
88_A91_A1.1581.00
54_I78_L1.1521.00
18_I27_L1.1481.00
29_I33_A1.1481.00
83_L99_S1.1191.00
74_L78_L1.1151.00
12_I63_L1.1091.00
47_A53_R1.0961.00
4_E26_R1.0951.00
69_E73_D1.0941.00
5_L9_E1.0851.00
87_A90_S1.0831.00
68_P72_H1.0791.00
92_R96_D1.0711.00
94_L97_E1.0651.00
93_A97_E1.0511.00
119_P122_E1.0471.00
9_E38_E1.0261.00
98_I117_L1.0211.00
2_K26_R1.0111.00
118_I122_E0.9981.00
91_A94_L0.9721.00
120_Y124_L0.9611.00
51_A118_I0.9531.00
58_V114_A0.9491.00
10_R17_V0.9481.00
96_D100_N0.9451.00
58_V110_A0.9441.00
16_A31_N0.9401.00
42_L46_E0.9260.99
69_E72_H0.9260.99
54_I79_V0.9210.99
37_R40_D0.9170.99
88_A120_Y0.9060.99
71_Y74_L0.9010.99
40_D115_R0.8990.99
115_R119_P0.8970.99
47_A52_R0.8840.99
90_S120_Y0.8750.99
68_P107_Y0.8620.99
59_Q114_A0.8580.99
64_D68_P0.8560.99
42_L47_A0.8490.99
8_G22_D0.8430.99
14_N33_A0.8410.99
116_K119_P0.8310.99
26_R35_I0.8210.99
80_R86_F0.8180.99
42_L55_Y0.8030.99
82_L94_L0.7950.98
54_I95_L0.7720.98
58_V107_Y0.7690.98
82_L95_L0.7650.98
97_E116_K0.7450.98
61_M71_Y0.7450.98
79_V95_L0.7440.98
57_A74_L0.7420.98
58_V75_Y0.7280.97
40_D109_K0.7270.97
86_F91_A0.7230.97
44_P57_A0.7160.97
83_L95_L0.7110.97
59_Q112_K0.7080.97
90_S123_E0.7020.97
10_R19_T0.6880.96
84_Q89_P0.6700.96
34_P61_M0.6680.95
97_E100_N0.6630.95
19_T23_R0.6530.95
93_A104_A0.6510.95
100_N103_L0.6480.95
39_K47_A0.6440.94
8_G13_I0.6430.94
82_L88_A0.6410.94
72_H105_G0.6410.94
74_L77_R0.6360.94
84_Q87_A0.6330.94
120_Y123_E0.6300.94
21_G27_L0.6290.94
33_A109_K0.6270.94
118_I124_L0.6250.94
48_D122_E0.6240.94
15_G66_A0.6240.94
58_V102_V0.6130.93
114_A118_I0.6110.93
51_A114_A0.6080.93
80_R84_Q0.6060.92
58_V116_K0.6060.92
55_Y111_L0.5950.92
42_L49_T0.5900.91
11_I15_G0.5880.91
86_F92_R0.5860.91
16_A19_T0.5850.91
20_N27_L0.5830.91
11_I27_L0.5750.90
17_V31_N0.5700.90
97_E101_H0.5680.90
2_K28_L0.5680.90
10_R60_L0.5670.90
21_G28_L0.5620.89
44_P71_Y0.5610.89
101_H104_A0.5610.89
4_E7_P0.5510.88
76_F96_D0.5490.88
56_F104_A0.5490.88
93_A96_D0.5450.88
75_Y83_L0.5410.88
57_A71_Y0.5380.87
119_P123_E0.5350.87
6_K34_P0.5350.87
32_D66_A0.5340.87
8_G16_A0.5320.87
20_N40_D0.5310.87
32_D65_P0.5310.87
67_D71_Y0.5280.86
76_F80_R0.5280.86
4_E39_K0.5270.86
58_V61_M0.5260.86
69_E76_F0.5260.86
20_N37_R0.5220.86
19_T41_I0.5220.86
72_H107_Y0.5200.85
34_P62_Y0.5200.85
12_I111_L0.5150.85
8_G21_G0.5140.85
5_L24_R0.5140.85
4_E9_E0.5130.85
70_E74_L0.5130.85
13_I16_A0.5130.85
94_L113_A0.5120.85
72_H103_L0.5100.84
61_M72_H0.5100.84
60_L64_D0.5080.84
21_G26_R0.5070.84
1_L5_L0.5060.84
82_L86_F0.5060.84
8_G23_R0.5020.83
94_L116_K0.5020.83
26_R31_N0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wpvA 1 0.296 39 0.906 Contact Map
1vpzA 2 0.384 32.3 0.91 Contact Map
4krwA 2 0.328 27.5 0.913 Contact Map
2btiA 2 0.4 25.8 0.914 Contact Map
1t3oA 1 0.536 24.8 0.915 Contact Map
1ltlA 4 0.32 21.9 0.917 Contact Map
2jppA 2 0.336 21.8 0.917 Contact Map
2wnvB 1 0.312 17.9 0.92 Contact Map
4m2aA 1 0.2 16.2 0.921 Contact Map
1rj8A 3 0.32 16.1 0.922 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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