GREMLIN Database
FliD_C - Flagellar hook-associated protein 2 C-terminus
PFAM: PF07195 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 240 (224)
Sequences: 16530 (13396)
Seq/√Len: 895.0
META: 0.807

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
68_S134_T3.3271.00
53_K143_D3.1511.00
5_K12_T2.9721.00
149_N152_A2.9151.00
221_E225_R2.7461.00
57_K139_E2.5891.00
7_T12_T2.4981.00
3_D14_T2.4671.00
53_K139_E2.4341.00
57_K61_D2.3201.00
129_D136_S2.2721.00
220_L223_R2.1901.00
5_K14_T2.1771.00
69_T73_L2.1461.00
15_S22_D2.0161.00
54_D58_S2.0061.00
222_A226_A1.9351.00
226_A230_A1.9181.00
129_D134_T1.9101.00
3_D16_S1.8691.00
68_S72_S1.8521.00
61_D65_A1.8481.00
6_F20_I1.8111.00
19_T30_T1.7791.00
144_A148_S1.7781.00
137_L142_L1.7291.00
20_I31_L1.7131.00
124_I156_L1.7041.00
6_F13_I1.6861.00
214_E218_E1.6851.00
215_D219_A1.6661.00
143_D147_A1.6641.00
53_K57_K1.6611.00
139_E143_D1.6591.00
218_E222_A1.6241.00
220_L224_L1.6151.00
50_D54_D1.5991.00
208_D212_D1.5981.00
62_A65_A1.5891.00
138_D141_K1.5641.00
218_E221_E1.5531.00
95_D195_R1.5511.00
49_T147_A1.5411.00
120_S123_D1.5391.00
119_S123_D1.5051.00
223_R227_Q1.5021.00
108_A180_L1.4951.00
50_D143_D1.4911.00
60_V137_L1.4851.00
48_D51_A1.4771.00
58_S62_A1.4601.00
57_K137_L1.4291.00
233_T237_Q1.4101.00
211_D215_D1.4101.00
200_N204_K1.4091.00
35_T41_V1.4021.00
90_G93_A1.3981.00
229_T233_T1.3881.00
67_I102_Q1.3621.00
207_D211_D1.3571.00
213_L217_L1.3561.00
212_D215_D1.3551.00
54_D57_K1.3321.00
213_L216_R1.3211.00
65_A69_T1.3001.00
104_Q180_L1.2981.00
58_S61_D1.2771.00
66_L70_I1.2631.00
180_L184_Y1.2571.00
69_T72_S1.2501.00
49_T143_D1.2381.00
222_A225_R1.2371.00
209_Q212_D1.2361.00
219_A222_A1.2251.00
178_D182_D1.2191.00
8_V23_A1.2151.00
51_A54_D1.1981.00
225_R229_T1.1971.00
20_I23_A1.1911.00
231_M235_L1.1811.00
4_A31_L1.1751.00
60_V126_I1.1711.00
131_D134_T1.1691.00
55_A58_S1.1621.00
56_I142_L1.1401.00
151_D155_A1.1381.00
76_Y93_A1.1331.00
127_T136_S1.1311.00
124_I153_V1.1261.00
155_A159_G1.1201.00
186_D193_T1.1131.00
65_A68_S1.1031.00
142_L146_L1.1031.00
196_T200_N1.0991.00
67_I134_T1.0971.00
197_D201_S1.0961.00
63_Y135_L1.0951.00
4_A18_N1.0941.00
6_F15_S1.0931.00
2_Q5_K1.0931.00
70_I102_Q1.0931.00
202_Q205_D1.0861.00
203_I207_D1.0801.00
127_T138_D1.0791.00
21_T28_T1.0631.00
205_D209_Q1.0611.00
27_V45_V1.0571.00
152_A155_A1.0551.00
215_D218_E1.0471.00
76_Y83_D1.0381.00
140_T144_A1.0351.00
71_N102_Q1.0331.00
207_D210_I1.0291.00
230_A234_A1.0201.00
100_S104_Q1.0171.00
210_I214_E1.0121.00
171_T179_D1.0101.00
35_T38_G1.0091.00
193_T197_D1.0081.00
101_L184_Y1.0031.00
36_P39_T1.0021.00
219_A223_R1.0011.00
74_T98_L0.9961.00
171_T175_T0.9931.00
212_D216_R0.9881.00
154_A158_T0.9821.00
51_A55_A0.9811.00
13_I23_A0.9811.00
102_Q106_R0.9771.00
151_D154_A0.9751.00
156_L173_L0.9731.00
56_I126_I0.9721.00
234_A237_Q0.9671.00
201_S205_D0.9641.00
107_S111_S0.9591.00
141_K145_A0.9581.00
230_A233_T0.9571.00
204_K208_D0.9521.00
128_T135_L0.9501.00
53_K137_L0.9461.00
86_T89_A0.9421.00
67_I71_N0.9311.00
206_L210_I0.9291.00
234_A238_L0.9281.00
184_Y191_L0.9271.00
175_T179_D0.9261.00
208_D211_D0.9191.00
203_I206_L0.9161.00
211_D214_E0.9161.00
6_F31_L0.9151.00
63_Y67_I0.9131.00
150_P154_A0.9111.00
50_D53_K0.9091.00
196_T199_L0.9061.00
111_S176_R0.9061.00
109_L135_L0.9051.00
145_A148_S0.9051.00
217_L220_L0.9031.00
201_S204_K0.8991.00
103_S107_S0.8981.00
35_T39_T0.8921.00
15_S20_I0.8921.00
76_Y87_A0.8811.00
23_A29_L0.8781.00
52_I55_A0.8761.00
74_T102_Q0.8751.00
121_L126_I0.8681.00
217_L221_E0.8671.00
108_A176_R0.8671.00
24_I27_V0.8661.00
89_A93_A0.8621.00
35_T40_P0.8601.00
73_L91_P0.8601.00
56_I137_L0.8591.00
83_D86_T0.8581.00
97_T100_S0.8581.00
106_R128_T0.8581.00
117_S152_A0.8521.00
231_M234_A0.8491.00
141_K144_A0.8471.00
224_L228_F0.8461.00
198_S202_Q0.8441.00
96_S99_R0.8441.00
200_N203_I0.8391.00
92_L98_L0.8331.00
99_R103_S0.8301.00
193_T196_T0.8291.00
197_D200_N0.8281.00
216_R220_L0.8241.00
179_D182_D0.8211.00
118_Y124_I0.8211.00
176_R179_D0.8201.00
72_S75_K0.8181.00
194_T198_S0.8171.00
126_I135_L0.8131.00
182_D186_D0.8081.00
146_L153_V0.8011.00
179_D183_S0.7991.00
52_I150_P0.7921.00
32_K35_T0.7871.00
104_Q183_S0.7871.00
204_K207_D0.7841.00
62_A66_L0.7831.00
60_V135_L0.7811.00
205_D208_D0.7741.00
180_L183_S0.7661.00
195_R198_S0.7651.00
20_I29_L0.7621.00
6_F12_T0.7611.00
99_R102_Q0.7551.00
206_L209_Q0.7531.00
140_T143_D0.7491.00
115_S119_S0.7481.00
171_T176_R0.7481.00
107_S110_S0.7471.00
210_I213_L0.7451.00
144_A147_A0.7431.00
176_R180_L0.7411.00
70_I73_L0.7381.00
8_V13_I0.7361.00
115_S118_Y0.7341.00
213_L220_L0.7301.00
194_T197_D0.7281.00
178_D181_L0.7261.00
188_G193_T0.7231.00
209_Q213_L0.7221.00
104_Q107_S0.7211.00
71_N134_T0.7191.00
159_G171_T0.7191.00
182_D185_T0.7161.00
226_A229_T0.7091.00
118_Y123_D0.7071.00
210_I232_E0.7061.00
183_S186_D0.7031.00
70_I98_L0.7021.00
4_A15_S0.6951.00
224_L227_Q0.6931.00
66_L105_L0.6881.00
223_R226_A0.6831.00
235_L239_N0.6791.00
232_E236_S0.6741.00
227_Q230_A0.6691.00
108_A111_S0.6651.00
49_T52_I0.6651.00
118_Y156_L0.6641.00
15_S23_A0.6621.00
82_E85_E0.6591.00
88_K91_P0.6561.00
71_N75_K0.6551.00
235_L238_L0.6541.00
228_F231_M0.6521.00
67_I106_R0.6481.00
98_L102_Q0.6461.00
118_Y145_A0.6421.00
96_S100_S0.6391.00
84_E87_A0.6381.00
60_V64_N0.6331.00
221_E224_L0.6311.00
15_S21_T0.6281.00
63_Y105_L0.6271.00
159_G175_T0.6271.00
49_T150_P0.6251.00
175_T178_D0.6241.00
57_K60_V0.6231.00
118_Y149_N0.6231.00
118_Y152_A0.6201.00
233_T236_S0.6201.00
84_E88_K0.6191.00
74_T99_R0.6171.00
63_Y106_R0.6161.00
15_S18_N0.6161.00
56_I157_F0.6151.00
145_A153_V0.6121.00
94_G99_R0.6101.00
122_S127_T0.6091.00
60_V142_L0.6081.00
216_R219_A0.6081.00
127_T141_K0.6071.00
52_I146_L0.6021.00
102_Q108_A0.6011.00
157_F169_S0.5981.00
195_R199_L0.5921.00
27_V30_T0.5901.00
97_T191_L0.5881.00
41_V44_T0.5861.00
34_A37_G0.5851.00
172_G176_R0.5831.00
73_L76_Y0.5811.00
53_K142_L0.5781.00
76_Y89_A0.5761.00
103_S106_R0.5741.00
74_T90_G0.5741.00
187_S190_G0.5741.00
19_T28_T0.5721.00
209_Q216_R0.5701.00
95_D98_L0.5671.00
54_D61_D0.5661.00
17_S20_I0.5631.00
54_D139_E0.5621.00
104_Q108_A0.5611.00
75_K93_A0.5611.00
160_D175_T0.5591.00
160_D170_T0.5571.00
47_R150_P0.5571.00
159_G169_S0.5561.00
228_F232_E0.5541.00
33_K39_T0.5471.00
46_S49_T0.5441.00
22_D31_L0.5431.00
102_Q105_L0.5431.00
214_E220_L0.5421.00
59_F63_Y0.5421.00
122_S128_T0.5411.00
146_L150_P0.5401.00
147_A150_P0.5351.00
160_D169_S0.5321.00
100_S103_S0.5321.00
137_L146_L0.5291.00
6_F29_L0.5261.00
37_G40_P0.5221.00
186_D190_G0.5191.00
97_T195_R0.5161.00
59_F177_L0.5161.00
49_T146_L0.5161.00
114_G118_Y0.5161.00
113_V176_R0.5121.00
4_A20_I0.5101.00
181_L185_T0.5081.00
22_D29_L0.5081.00
131_D136_S0.5051.00
66_L69_T0.5021.00
31_L34_A0.5001.00
121_L173_L0.5001.00
170_T175_T0.5001.00
53_K56_I0.5001.00
93_A98_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ghgA 2 0.5667 66.2 0.917 Contact Map
3swyA 3 0.1917 43.5 0.927 Contact Map
1deqA 1 0.5 33.3 0.932 Contact Map
2z5iA 3 0.2083 32.2 0.933 Contact Map
1x8yA 2 0.1583 31.3 0.933 Contact Map
1gk4A 2 0.1958 27.8 0.935 Contact Map
2xdjA 3 0.2875 27.1 0.935 Contact Map
3nftA 2 0.75 26.2 0.935 Contact Map
3tnuA 2 0.2417 22.9 0.937 Contact Map
3swfA 3 0.2167 21.9 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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