GREMLIN Database
DUF1302 - Protein of unknown function (DUF1302)
PFAM: PF06980 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 546 (541)
Sequences: 2923 (2079)
Seq/√Len: 89.4
META: 0.65

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
182_N202_F5.0971.00
139_L184_L4.2601.00
418_Y453_F4.2481.00
23_T538_V3.9681.00
328_F339_G3.9251.00
9_G69_L3.8821.00
284_N322_K3.7631.00
280_L326_L3.7341.00
420_H453_F3.4641.00
135_L188_L3.3891.00
17_Y59_N3.3321.00
25_D53_K3.2991.00
474_L506_L3.2251.00
391_T422_L3.2051.00
141_R182_N3.1771.00
284_N320_D3.1421.00
26_P52_D3.0991.00
474_L508_A3.0531.00
182_N203_E3.0501.00
271_A278_F3.0111.00
194_L269_Y3.0031.00
282_Y322_K2.9581.00
75_Y126_G2.8941.00
133_M188_L2.8271.00
20_S57_V2.8181.00
457_Y482_H2.7681.00
345_P389_D2.6861.00
335_T399_K2.6661.00
341_L391_T2.6561.00
514_W542_V2.6221.00
455_W484_V2.5781.00
341_L393_A2.5551.00
251_R254_D2.5471.00
19_A56_L2.5471.00
196_L267_L2.5211.00
346_N389_D2.5131.00
161_P181_V2.4821.00
142_Q185_S2.4791.00
79_V122_A2.4161.00
13_T63_G2.4011.00
11_F65_S2.3841.00
139_L202_F2.3611.00
252_G312_S2.3451.00
322_K346_N2.3281.00
507_D517_D2.2721.00
144_V183_M2.2271.00
286_H319_E2.2051.00
77_A124_V2.1991.00
11_F67_L2.1801.00
76_G125_Y2.1531.00
168_R210_D2.1481.00
257_P319_E2.1441.00
13_T65_S2.1391.00
468_V474_L2.1251.00
268_R277_E2.1161.00
126_G135_L2.1051.00
21_W56_L2.0971.00
141_R203_E2.0801.00
464_T475_S2.0761.00
293_S316_E2.0601.00
516_A540_L2.0471.00
63_G83_A2.0291.00
197_E266_A2.0041.00
455_W485_K1.9931.00
472_V508_A1.9911.00
81_G117_A1.9631.00
207_T289_L1.9621.00
51_F89_L1.9451.00
477_P505_G1.9451.00
282_Y324_Y1.9411.00
518_L540_L1.9361.00
128_F137_V1.8911.00
129_D132_D1.8701.00
93_N96_P1.8561.00
351_I386_A1.8511.00
335_T397_A1.8371.00
269_Y280_L1.8051.00
62_K176_E1.7971.00
349_L390_T1.7961.00
337_V397_A1.7931.00
65_S83_A1.7921.00
88_E95_R1.7901.00
24_E522_N1.7881.00
144_V185_S1.7861.00
408_D466_N1.7681.00
337_V395_L1.7641.00
457_Y484_V1.7591.00
150_L396_T1.7581.00
283_M323_L1.7501.00
113_A214_T1.7481.00
167_L177_A1.7421.00
410_L461_F1.7211.00
338_G396_T1.6991.00
514_W544_Y1.6941.00
496_N499_R1.6811.00
9_G67_L1.6771.00
347_M390_T1.6741.00
261_G286_H1.6681.00
119_L122_A1.6461.00
2_F9_G1.6421.00
285_Y323_L1.6411.00
462_T475_S1.6311.00
20_S58_S1.6311.00
105_F109_A1.6261.00
135_L186_A1.6041.00
500_K524_F1.6021.00
46_D220_D1.6001.00
262_Q286_H1.5971.00
516_A542_V1.5921.00
255_R314_F1.5891.00
199_F283_M1.5851.00
83_A117_A1.5811.00
187_S195_S1.5571.00
149_S394_Q1.5571.00
56_L59_N1.5481.00
181_V201_Q1.5411.00
193_N272_E1.5171.00
472_V510_Y1.4911.00
286_H320_D1.4901.00
324_Y345_P1.4841.00
206_P317_Y1.4721.00
321_I348_P1.4680.99
338_G398_T1.4650.99
191_T194_L1.4580.99
137_V184_L1.4510.99
457_Y480_F1.4360.99
416_V455_W1.4270.99
271_A274_L1.4260.99
465_Y476_P1.4240.99
137_V186_A1.4170.99
451_T487_N1.4160.99
23_T26_P1.4120.99
194_L267_L1.4120.99
70_K125_Y1.4100.99
257_P286_H1.4010.99
346_N387_R1.3970.99
502_L524_F1.3960.99
505_G519_S1.3940.99
203_E259_D1.3930.99
159_I199_F1.3910.99
6_D72_G1.3900.99
200_Y261_G1.3900.99
386_A429_Y1.3900.99
377_A380_Q1.3890.99
519_S539_S1.3850.99
251_R313_Y1.3810.99
502_L522_N1.3630.99
186_A198_A1.3580.99
255_R316_E1.3540.99
128_F135_L1.3510.99
173_E543_K1.3310.99
190_L267_L1.3240.99
57_V215_Y1.3180.99
293_S314_F1.3160.99
19_A59_N1.3150.99
410_L463_P1.3120.99
16_S62_K1.3100.99
7_L71_Y1.3090.99
287_S321_I1.3070.99
156_I342_S1.2940.99
2_F5_G1.2900.99
322_K345_P1.2870.99
23_T54_G1.2840.99
31_I49_L1.2700.99
280_L324_Y1.2630.98
343_Y391_T1.2600.98
144_V199_F1.2530.98
481_S501_S1.2450.98
254_D315_L1.2440.98
397_A414_G1.2410.98
113_A211_P1.2400.98
517_D541_S1.2340.98
201_Q288_R1.2270.98
469_F472_V1.2260.98
407_A465_Y1.2210.98
223_G226_G1.2200.98
349_L388_G1.2180.98
414_G459_L1.2150.98
64_L82_A1.2130.98
20_S539_S1.2110.98
482_H500_K1.2100.98
477_P517_D1.2100.98
258_R320_D1.2050.98
134_P189_G1.2020.98
79_V119_L1.2000.98
174_L178_L1.1930.98
32_G42_P1.1920.98
23_T215_Y1.1880.98
485_K497_E1.1820.98
458_R481_S1.1790.98
515_T543_K1.1720.97
198_A265_V1.1710.97
52_D55_D1.1700.97
480_F500_K1.1700.97
388_G429_Y1.1690.97
401_F410_L1.1660.97
3_D6_D1.1630.97
271_A276_T1.1630.97
31_I45_D1.1600.97
158_S283_M1.1540.97
430_G436_G1.1520.97
164_V209_L1.1440.97
505_G517_D1.1420.97
252_G314_F1.1380.97
390_T421_V1.1380.97
509_D512_N1.1360.97
393_A418_Y1.1330.97
156_I323_L1.1320.97
59_N87_F1.1280.97
388_G425_P1.1230.97
22_R48_N1.1210.97
261_G284_N1.1210.97
468_V473_D1.1170.97
255_R381_D1.1150.97
416_V484_V1.1120.97
92_D95_R1.1110.97
470_P473_D1.1020.96
522_N536_D1.0960.96
80_R121_D1.0950.96
525_G530_N1.0920.96
89_L95_R1.0910.96
14_T543_K1.0870.96
118_E208_R1.0860.96
274_L278_F1.0860.96
8_E70_K1.0840.96
3_D8_E1.0830.96
47_G50_N1.0800.96
341_L422_L1.0800.96
429_Y433_G1.0790.96
212_C223_G1.0780.96
258_R319_E1.0780.96
361_A365_P1.0760.96
81_G119_L1.0760.96
88_E92_D1.0740.96
15_L63_G1.0690.96
101_S104_G1.0630.96
57_V216_F1.0620.96
445_E448_G1.0590.95
483_D499_R1.0590.95
150_L398_T1.0570.95
263_F284_N1.0540.95
420_H452_R1.0530.95
430_G433_G1.0520.95
152_I417_G1.0490.95
106_S109_A1.0490.95
335_T412_L1.0470.95
222_A315_L1.0450.95
366_L369_G1.0390.95
216_F537_F1.0390.95
69_L77_A1.0370.95
404_T410_L1.0370.95
150_L413_V1.0350.95
405_L463_P1.0320.95
475_S509_D1.0310.95
65_S81_G1.0310.95
133_M190_L1.0250.95
151_F460_R1.0240.95
293_S350_Q1.0130.94
87_F92_D1.0130.94
17_Y61_L1.0120.94
89_L94_D1.0110.94
397_A416_V1.0110.94
412_L459_L1.0080.94
88_E93_N1.0050.94
218_T531_L1.0040.94
322_K389_D1.0020.94
425_P429_Y0.9990.94
371_S374_G0.9990.94
141_R205_E0.9980.94
89_L96_P0.9960.94
45_D49_L0.9920.94
43_N46_D0.9900.93
513_K544_Y0.9880.93
278_F328_F0.9880.93
261_G320_D0.9880.93
26_P31_I0.9870.93
89_L93_N0.9860.93
263_F282_Y0.9840.93
172_A177_A0.9770.93
91_K94_D0.9700.93
468_V506_L0.9650.93
398_T413_V0.9650.93
11_F83_A0.9540.92
361_A364_S0.9500.92
193_N269_Y0.9480.92
148_E327_S0.9470.92
330_T339_G0.9470.92
276_T330_T0.9440.92
164_V167_L0.9430.92
82_A166_K0.9400.92
91_K95_R0.9400.92
411_T464_T0.9380.91
199_F288_R0.9350.91
201_Q262_Q0.9350.91
102_D105_F0.9340.91
318_P348_P0.9310.91
294_G357_L0.9300.91
66_E78_F0.9270.91
94_D97_F0.9180.91
74_N126_G0.9150.90
271_A275_N0.9130.90
316_E383_P0.9100.90
23_T53_K0.9080.90
507_D515_T0.9080.90
130_L135_L0.9060.90
419_T490_G0.9040.90
27_D30_L0.9030.90
35_N49_L0.9010.90
235_A238_D0.8980.90
291_Q318_P0.8980.90
343_Y422_L0.8970.90
249_V311_G0.8970.90
152_I394_Q0.8910.89
430_G435_F0.8900.89
332_L337_V0.8890.89
365_P369_G0.8880.89
77_A81_G0.8880.89
508_A516_A0.8870.89
66_E80_R0.8870.89
428_R431_R0.8860.89
276_T328_F0.8830.89
45_D220_D0.8820.89
7_L69_L0.8800.89
150_L338_G0.8790.89
126_G137_V0.8770.89
391_T420_H0.8680.88
421_V489_P0.8670.88
389_D423_D0.8670.88
164_V207_T0.8660.88
46_D50_N0.8660.88
287_S318_P0.8660.88
71_Y75_Y0.8650.88
162_V178_L0.8630.88
179_L205_E0.8610.88
133_M191_T0.8600.88
127_N136_S0.8600.88
13_T83_A0.8590.87
287_S291_Q0.8560.87
155_G456_G0.8550.87
438_N441_P0.8520.87
347_M490_G0.8520.87
252_G255_R0.8520.87
77_A122_A0.8510.87
46_D49_L0.8440.87
273_E276_T0.8440.87
139_L182_N0.8410.86
478_L504_L0.8380.86
190_L196_L0.8370.86
516_A543_K0.8360.86
409_Q466_N0.8300.86
33_K38_G0.8300.86
409_Q464_T0.8270.85
78_F121_D0.8250.85
155_G488_S0.8240.85
509_D513_K0.8230.85
133_M189_G0.8220.85
393_A416_V0.8210.85
303_A306_A0.8210.85
237_P240_G0.8180.85
430_G434_T0.8160.85
33_K37_G0.8160.85
407_A463_P0.8160.85
526_G530_N0.8150.85
166_K169_V0.8130.84
111_D116_G0.8130.84
342_S392_Q0.8120.84
350_Q356_L0.8080.84
163_D166_K0.8070.84
454_S489_P0.8070.84
457_Y500_K0.8060.84
79_V124_V0.8050.84
129_D134_P0.8030.84
503_S519_S0.8020.84
407_A461_F0.8010.84
88_E96_P0.8000.83
510_Y516_A0.7980.83
226_G251_R0.7960.83
235_A239_P0.7930.83
390_T419_T0.7880.83
458_R479_A0.7880.83
367_L370_G0.7850.82
244_G247_L0.7850.82
181_V205_E0.7840.82
483_D495_F0.7840.82
292_L315_L0.7840.82
145_S155_G0.7830.82
145_S396_T0.7810.82
475_S507_D0.7800.82
289_L491_P0.7790.82
100_L105_F0.7750.81
344_R390_T0.7740.81
305_L308_A0.7730.81
258_R286_H0.7720.81
85_Y115_S0.7720.81
285_Y288_R0.7630.80
458_R483_D0.7630.80
268_R279_G0.7620.80
419_T488_S0.7620.80
23_T520_Y0.7610.80
291_Q347_M0.7600.80
32_G35_N0.7560.80
232_G238_D0.7550.80
526_G533_R0.7550.80
431_R434_T0.7530.80
343_Y389_D0.7510.79
263_F267_L0.7500.79
498_G525_G0.7490.79
215_Y333_G0.7470.79
143_V178_L0.7470.79
212_C227_C0.7450.79
413_V460_R0.7430.79
320_D423_D0.7420.79
104_G109_A0.7420.79
450_A487_N0.7410.79
157_N178_L0.7400.78
66_E175_K0.7380.78
437_A441_P0.7370.78
427_L432_P0.7350.78
412_L461_F0.7340.78
401_F412_L0.7330.78
466_N473_D0.7310.78
209_L223_G0.7290.77
160_N183_M0.7280.77
141_R202_F0.7260.77
471_G511_L0.7260.77
474_L516_A0.7260.77
379_G382_I0.7240.77
85_Y114_G0.7240.77
105_F211_P0.7230.77
398_T411_T0.7220.77
285_Y347_M0.7200.77
479_A503_S0.7190.76
74_N127_N0.7180.76
328_F395_L0.7170.76
493_G498_G0.7170.76
364_S368_A0.7170.76
109_A214_T0.7150.76
238_D241_G0.7150.76
257_P261_G0.7150.76
270_F277_E0.7140.76
263_F322_K0.7120.76
279_G327_S0.7110.76
33_K36_G0.7100.76
441_P445_E0.7100.76
221_F226_G0.7090.75
269_Y272_E0.7090.75
468_V508_A0.7080.75
373_L376_V0.7080.75
400_V409_Q0.7080.75
521_T537_F0.7070.75
26_P30_L0.7050.75
204_W256_E0.7040.75
431_R436_G0.7020.75
148_E329_N0.7020.75
314_F381_D0.7010.75
225_G229_L0.6990.74
3_D215_Y0.6990.74
124_V139_L0.6980.74
89_L114_G0.6980.74
421_V424_L0.6970.74
432_P435_F0.6970.74
111_D115_S0.6970.74
18_G62_K0.6950.74
59_N88_E0.6940.74
397_A412_L0.6910.74
193_N271_A0.6910.74
480_F484_V0.6910.74
2_F6_D0.6910.74
153_Q167_L0.6900.73
258_R261_G0.6890.73
339_G393_A0.6880.73
361_A370_G0.6880.73
400_V411_T0.6870.73
235_A240_G0.6870.73
167_L174_L0.6860.73
206_P254_D0.6860.73
92_D96_P0.6850.73
154_N494_N0.6840.73
204_W257_P0.6810.72
393_A397_A0.6800.72
419_T489_P0.6800.72
340_E394_Q0.6790.72
183_M203_E0.6780.72
321_I387_R0.6770.72
369_G372_Q0.6760.72
535_R546_F0.6740.72
366_L370_G0.6720.71
285_Y321_I0.6710.71
367_L371_S0.6710.71
93_N97_F0.6700.71
238_D242_P0.6700.71
458_R501_S0.6690.71
429_Y432_P0.6680.71
399_K412_L0.6680.71
395_L416_V0.6680.71
196_L265_V0.6670.71
322_K387_R0.6650.71
184_L453_F0.6650.71
259_D286_H0.6630.70
300_A303_A0.6630.70
53_K345_P0.6610.70
429_Y436_G0.6600.70
293_S384_G0.6590.70
120_L176_E0.6580.70
169_V172_A0.6570.70
75_Y128_F0.6570.70
116_G166_K0.6570.70
145_S178_L0.6570.70
480_F502_L0.6550.70
376_V380_Q0.6550.70
158_S285_Y0.6550.70
118_E179_L0.6540.69
62_K82_A0.6520.69
440_N443_G0.6510.69
233_F238_D0.6510.69
131_G134_P0.6510.69
490_G499_R0.6510.69
141_R179_L0.6500.69
509_D515_T0.6500.69
107_D111_D0.6490.69
451_T497_E0.6480.69
523_F532_L0.6480.69
102_D106_S0.6470.69
365_P368_A0.6470.69
490_G494_N0.6450.68
21_W54_G0.6440.68
124_V265_V0.6440.68
66_E121_D0.6440.68
433_G436_G0.6390.68
342_S394_Q0.6390.68
334_G399_K0.6390.68
17_Y60_R0.6380.68
365_P370_G0.6370.67
276_T339_G0.6360.67
417_G495_F0.6360.67
27_D533_R0.6350.67
504_L538_V0.6350.67
437_A440_N0.6330.67
523_F537_F0.6330.67
527_G530_N0.6320.67
151_F458_R0.6320.67
74_N129_D0.6310.67
107_D110_R0.6310.67
467_N470_P0.6300.67
431_R435_F0.6300.67
105_F110_R0.6300.67
206_P224_A0.6300.67
473_D509_D0.6300.67
527_G533_R0.6290.66
64_L120_L0.6280.66
442_N445_E0.6280.66
472_V516_A0.6270.66
161_P288_R0.6270.66
11_F63_G0.6260.66
67_L81_G0.6260.66
55_D95_R0.6260.66
146_W283_M0.6260.66
269_Y278_F0.6250.66
431_R487_N0.6250.66
145_S175_K0.6250.66
364_S370_G0.6240.66
72_G75_Y0.6240.66
88_E94_D0.6240.66
291_Q316_E0.6240.66
299_A303_A0.6230.66
291_Q385_Y0.6220.66
121_D336_A0.6220.66
255_R293_S0.6220.66
104_G108_A0.6220.66
221_F292_L0.6210.65
259_D319_E0.6190.65
30_L215_Y0.6190.65
440_N444_C0.6180.65
427_L434_T0.6180.65
183_M283_M0.6170.65
229_L232_G0.6170.65
222_A292_L0.6170.65
221_F357_L0.6160.65
200_Y260_S0.6150.65
4_T7_L0.6140.65
84_W544_Y0.6140.65
14_T545_S0.6140.65
438_N442_N0.6140.65
502_L536_D0.6120.64
41_S44_G0.6100.64
218_T532_L0.6090.64
221_F229_L0.6090.64
82_A176_E0.6070.64
428_R433_G0.6070.64
491_P494_N0.6070.64
356_L384_G0.6060.64
189_G195_S0.6060.64
294_G356_L0.6060.64
368_A374_G0.6040.63
30_L48_N0.6010.63
454_S488_S0.6010.63
364_S367_L0.6010.63
119_L141_R0.6010.63
439_A442_N0.6000.63
221_F294_G0.5990.63
520_Y536_D0.5990.63
259_D284_N0.5990.63
91_K115_S0.5990.63
28_P52_D0.5990.63
421_V488_S0.5980.63
217_S535_R0.5950.62
371_S376_V0.5940.62
429_Y434_T0.5930.62
83_A115_S0.5930.62
57_V537_F0.5920.62
371_S375_A0.5920.62
405_L461_F0.5910.62
25_D52_D0.5910.62
60_R169_V0.5900.61
275_N330_T0.5900.61
427_L430_G0.5890.61
389_D422_L0.5880.61
287_S348_P0.5880.61
323_L344_R0.5880.61
158_S323_L0.5880.61
88_E91_K0.5870.61
503_S521_T0.5860.61
237_P242_P0.5850.61
216_F521_T0.5850.61
77_A139_L0.5850.61
441_P444_C0.5830.61
424_L452_R0.5830.61
321_I347_M0.5810.60
444_C447_D0.5810.60
66_E173_E0.5790.60
439_A443_G0.5790.60
417_G456_G0.5780.60
152_I174_L0.5780.60
301_A305_L0.5770.60
211_P224_A0.5740.59
47_G217_S0.5740.59
31_I46_D0.5740.59
148_E279_G0.5730.59
43_N50_N0.5730.59
311_G360_A0.5720.59
416_V459_L0.5720.59
8_E130_L0.5720.59
428_R434_T0.5710.59
31_I35_N0.5710.59
112_L165_S0.5700.59
215_Y537_F0.5700.59
345_P387_R0.5690.59
238_D243_A0.5690.59
228_R248_A0.5680.59
139_L200_Y0.5680.59
106_S225_G0.5680.59
149_S396_T0.5680.59
259_D497_E0.5670.58
121_D143_V0.5670.58
134_P191_T0.5660.58
372_Q375_A0.5650.58
155_G158_S0.5640.58
254_D257_P0.5630.58
321_I346_N0.5630.58
153_Q289_L0.5630.58
329_N398_T0.5610.58
250_P312_S0.5590.57
336_A396_T0.5580.57
103_D109_A0.5580.57
138_R177_A0.5580.57
212_C226_G0.5580.57
148_E268_R0.5580.57
239_P242_P0.5580.57
361_A367_L0.5570.57
275_N454_S0.5560.57
123_F344_R0.5550.57
92_D442_N0.5550.57
354_V357_L0.5540.57
108_A111_D0.5530.57
487_N497_E0.5530.57
152_I396_T0.5530.57
480_F524_F0.5520.56
149_S152_I0.5520.56
182_N205_E0.5510.56
364_S369_G0.5510.56
351_I356_L0.5510.56
405_L408_D0.5510.56
453_F485_K0.5500.56
48_N55_D0.5500.56
47_G51_F0.5500.56
536_D544_Y0.5500.56
281_Y327_S0.5490.56
517_D543_K0.5490.56
145_S159_I0.5490.56
64_L176_E0.5490.56
26_P49_L0.5490.56
232_G239_P0.5480.56
272_E278_F0.5480.56
236_L243_A0.5480.56
143_V160_N0.5470.56
406_G476_P0.5470.56
532_L535_R0.5470.56
316_E381_D0.5470.56
262_Q288_R0.5460.56
357_L360_A0.5450.56
370_G374_G0.5450.56
159_I183_M0.5450.56
105_F108_A0.5450.56
428_R435_F0.5440.55
82_A118_E0.5440.55
295_A298_A0.5440.55
142_Q268_R0.5440.55
145_S157_N0.5440.55
215_Y523_F0.5430.55
219_N226_G0.5430.55
275_N280_L0.5430.55
47_G532_L0.5420.55
124_V420_H0.5410.55
165_S479_A0.5410.55
432_P436_G0.5400.55
162_V167_L0.5390.55
437_A442_N0.5390.55
184_L202_F0.5390.55
234_G238_D0.5380.55
224_A317_Y0.5380.55
477_P507_D0.5360.54
56_L88_E0.5360.54
374_G381_D0.5360.54
14_T66_E0.5360.54
347_M389_D0.5360.54
7_L280_L0.5360.54
206_P256_E0.5360.54
329_N337_V0.5350.54
145_S283_M0.5340.54
233_F237_P0.5330.54
64_L80_R0.5330.54
131_G191_T0.5330.54
187_S197_E0.5330.54
403_P408_D0.5320.54
483_D494_N0.5320.54
48_N215_Y0.5320.54
361_A366_L0.5320.54
76_G126_G0.5310.54
48_N167_L0.5300.53
336_A398_T0.5290.53
8_E11_F0.5290.53
240_G243_A0.5290.53
297_G301_A0.5290.53
372_Q376_V0.5290.53
146_W197_E0.5280.53
444_C449_F0.5280.53
319_E497_E0.5280.53
130_L516_A0.5270.53
29_D38_G0.5270.53
159_I283_M0.5270.53
152_I456_G0.5270.53
372_Q377_A0.5260.53
107_D259_D0.5260.53
41_S45_D0.5250.53
16_S169_V0.5250.53
24_E536_D0.5250.53
344_R347_M0.5240.53
378_P382_I0.5230.53
15_L61_L0.5230.53
249_V294_G0.5220.52
134_P541_S0.5210.52
4_T8_E0.5210.52
168_R172_A0.5200.52
221_F353_D0.5200.52
324_Y346_N0.5190.52
487_N496_N0.5180.52
146_W264_G0.5180.52
55_D59_N0.5180.52
62_K80_R0.5180.52
365_P372_Q0.5180.52
444_C448_G0.5170.52
254_D317_Y0.5170.52
76_G123_F0.5170.52
68_D78_F0.5170.52
159_I490_G0.5160.52
174_L177_A0.5160.52
135_L139_L0.5160.52
50_N55_D0.5150.51
129_D133_M0.5150.51
522_N538_V0.5130.51
278_F326_L0.5120.51
153_Q174_L0.5110.51
373_L377_A0.5110.51
210_D214_T0.5110.51
368_A373_L0.5110.51
350_Q450_A0.5110.51
229_L233_F0.5100.51
60_R84_W0.5100.51
451_T486_G0.5090.51
519_S537_F0.5080.50
185_S266_A0.5080.50
307_A310_T0.5080.50
260_S286_H0.5070.50
304_G308_A0.5070.50
125_Y175_K0.5050.50
328_F338_G0.5050.50
167_L172_A0.5050.50
350_Q385_Y0.5050.50
89_L92_D0.5050.50
374_G377_A0.5040.50
206_P223_G0.5040.50
365_P374_G0.5030.50
448_G451_T0.5020.50
349_L397_A0.5020.50
79_V117_A0.5020.50
152_I458_R0.5010.49
293_S381_D0.5010.49
48_N52_D0.5010.49
506_L518_L0.5010.49
110_R115_S0.5010.49
84_W118_E0.5000.49
411_T462_T0.5000.49
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gufA 1 0.5733 51.4 0.977 Contact Map
3nb3A 2 0.2436 47.5 0.978 Contact Map
2ervA 1 0.2582 39.9 0.979 Contact Map
3qlbA 1 0.6062 39.7 0.979 Contact Map
3qraA 1 0.2729 39.4 0.979 Contact Map
2jmmA 1 0.2509 38.4 0.979 Contact Map
3efmA 1 0.6044 28.5 0.98 Contact Map
1qjpA 1 0.2436 28.4 0.98 Contact Map
1kmoA 1 0.6795 26.6 0.981 Contact Map
1ormA 1 0.2656 13.9 0.983 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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