CTI - PFAM28P - GREMLIN Contacts

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CTI - Fatty acid cis/trans isomerase (CTI)

PFAM:	PF06934	Sequences: MEPTRLFIDAQTTAEWREKGFFPVLNQTPEANLQASLLYRMLELKQQHPLPAGGLLPESFDLSLDREQQCPTIEEFDDYAKKHPLWGMPYGLPGLSDDEYQTLARWLAQGAPGPAPPPPSAAEQAQIAKWEAFLNGDSLKQQLVARYLYEHLFLAHLYFDDGPPGEFFRLVRSRTPPGQPIDEIATRRPYDDPGVERFYYRLRPIQSTIVHKTHMPYALSDARMARWRELFLDPDYEVTALPGYDPEVAANPFKTFAAIPARSRYQFLLDNAQYFIMGFIKGPVCRGQIALNVINDHFWVFFLDPDHDLSVTDPEFLAEQADNLRLPAEKGSNALLLSLWLKYAKKQNRYLKAKQDFYAKLFPDGLTLDLIWDGDGTNDNAALTVFRHFDSASVVKGLVGELPKTAWVIDYPLLERIHYLLVAGFDVYGNVGHQLNTRLYMDFLRMEGESNFLAFLPAEQRKAIRDSWYRGAGEKLKDYLDYPSADFDQPTGIGYKTDDPKRELYELLKQRLAPVLGRRDPINRCRGGPCRPGQSETLADAEQALRRLASLPGAGLKVISFLPEVAFLRVEDDDGKDLVYTLLRNRAHSNVASLFGEEKRRDPEEDTLTVVPGFIGSYPNFFFDVDESDLPDFVDALAALKSEADYEALVDRYGVRRTDPDFWEYSDWFHAYYRETQPVEAGLLDLNRYEN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	691 (687)
Sequences:	1017 (797)
Seq/√Len:	30.4
META:	0.719

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
174_R	182_D	6.211	1.00
567_F	684_L	5.447	1.00
248_V	255_T	5.103	1.00
138_S	141_Q	4.699	1.00
41_M	76_F	4.511	1.00
144_V	232_L	4.387	1.00
157_L	219_L	4.325	1.00
181_I	203_R	4.245	1.00
226_R	270_D	4.206	1.00
76_F	80_A	4.039	1.00
614_F	684_L	3.891	1.00
26_N	32_N	3.850	1.00
686_L	689_Y	3.712	1.00
585_N	607_T	3.691	1.00
187_R	426_D	3.587	1.00
497_T	503_E	3.492	1.00
567_F	614_F	3.370	1.00
501_K	505_Y	3.344	1.00
262_R	266_Q	3.335	1.00
160_D	220_S	3.275	1.00
40_R	77_D	3.198	1.00
642_S	645_D	3.147	1.00
632_D	653_Y	3.111	1.00
79_Y	86_W	3.025	1.00
169_R	183_E	3.020	1.00
470_R	605_E	3.002	1.00
588_H	597_E	2.979	1.00
171_V	181_I	2.920	1.00
129_K	221_D	2.899	1.00
395_V	399_V	2.800	1.00
136_G	141_Q	2.783	1.00
62_L	91_G	2.769	1.00
413_L	448_G	2.743	1.00
295_N	404_K	2.730	1.00
301_F	398_L	2.719	1.00
278_G	418_H	2.701	1.00
4_T	19_K	2.631	1.00
223_R	271_N	2.624	1.00
592_A	600_R	2.614	1.00
137_D	197_R	2.611	1.00
406_A	505_Y	2.601	1.00
371_I	408_V	2.599	1.00
297_H	585_N	2.593	1.00
262_R	306_D	2.581	1.00
148_L	268_L	2.566	1.00
564_E	586_R	2.559	1.00
408_V	455_F	2.549	0.99
499_D	502_R	2.542	0.99
169_R	203_R	2.533	0.99
601_R	606_D	2.507	0.99
520_D	523_N	2.489	0.99
273_Q	277_M	2.488	0.99
254_K	322_D	2.483	0.99
211_H	673_Y	2.482	0.99
455_F	504_L	2.477	0.99
226_R	230_L	2.471	0.99
239_T	258_A	2.466	0.99
320_Q	323_N	2.449	0.99
379_D	396_K	2.418	0.99
589_S	602_D	2.403	0.99
69_Q	83_H	2.396	0.99
464_I	501_K	2.382	0.99
666_S	686_L	2.378	0.99
641_K	645_D	2.361	0.99
586_R	601_R	2.359	0.99
190_Y	424_G	2.330	0.99
46_Q	97_D	2.317	0.99
568_L	582_L	2.278	0.99
39_Y	104_A	2.255	0.99
33_L	36_S	2.217	0.99
139_L	142_Q	2.208	0.99
456_L	464_I	2.201	0.98
566_A	623_F	2.185	0.98
155_A	274_Y	2.183	0.98
12_T	15_E	2.146	0.98
133_F	232_L	2.135	0.98
570_V	580_Y	2.130	0.98
579_V	614_F	2.112	0.98
650_V	654_G	2.105	0.98
275_F	414_L	2.105	0.98
126_Q	129_K	2.067	0.98
137_D	198_F	2.060	0.98
205_I	209_I	2.028	0.97
273_Q	396_K	2.022	0.97
623_F	633_F	2.019	0.97
124_Q	128_A	1.955	0.97
10_A	15_E	1.951	0.97
226_R	229_E	1.935	0.97
373_D	511_R	1.930	0.96
320_Q	353_A	1.926	0.96
2_E	19_K	1.924	0.96
211_H	617_S	1.900	0.96
266_Q	375_D	1.896	0.96
152_L	227_W	1.880	0.96
268_L	278_G	1.867	0.96
460_Q	463_A	1.852	0.96
5_R	9_D	1.851	0.96
547_R	635_D	1.850	0.96
552_P	555_G	1.848	0.95
71_P	75_E	1.838	0.95
467_S	470_R	1.823	0.95
141_Q	232_L	1.812	0.95
456_L	504_L	1.812	0.95
61_D	90_Y	1.793	0.95
649_L	653_Y	1.787	0.95
83_H	86_W	1.776	0.94
402_L	505_Y	1.774	0.94
266_Q	270_D	1.772	0.94
370_L	455_F	1.761	0.94
291_L	391_S	1.756	0.94
325_R	346_K	1.735	0.94
120_S	123_E	1.720	0.93
181_I	202_L	1.704	0.93
293_V	417_I	1.699	0.93
176_P	179_Q	1.690	0.93
386_F	609_T	1.689	0.93
190_Y	423_A	1.676	0.92
127_I	202_L	1.657	0.92
209_I	682_G	1.647	0.92
565_V	616_G	1.624	0.91
109_Q	112_P	1.622	0.91
249_A	328_A	1.621	0.91
26_N	31_A	1.611	0.91
389_F	588_H	1.586	0.90
288_Q	389_F	1.579	0.90
301_F	508_L	1.573	0.90
672_Y	676_T	1.564	0.90
328_A	437_T	1.540	0.89
139_L	241_L	1.535	0.89
602_D	605_E	1.522	0.88
399_V	611_V	1.520	0.88
571_E	626_D	1.518	0.88
684_L	687_N	1.510	0.88
55_L	62_L	1.497	0.87
160_D	218_A	1.497	0.87
156_H	209_I	1.490	0.87
8_I	183_E	1.489	0.87
14_A	18_E	1.486	0.87
44_L	76_F	1.486	0.87
655_V	659_D	1.475	0.87
452_F	501_K	1.471	0.86
289_I	425_F	1.471	0.86
274_Y	278_G	1.460	0.86
611_V	615_I	1.455	0.86
119_P	168_F	1.443	0.85
301_F	406_A	1.440	0.85
612_P	655_V	1.438	0.85
262_R	304_D	1.437	0.85
217_Y	230_L	1.436	0.85
195_V	198_F	1.426	0.85
683_L	687_N	1.421	0.84
100_Y	104_A	1.420	0.84
183_E	198_F	1.409	0.84
144_V	148_L	1.401	0.84
259_I	263_S	1.398	0.83
4_T	10_A	1.398	0.83
261_A	412_P	1.395	0.83
441_M	444_L	1.392	0.83
566_A	633_F	1.390	0.83
571_E	624_D	1.379	0.83
495_Y	503_E	1.378	0.82
152_L	217_Y	1.378	0.82
371_I	508_L	1.374	0.82
525_C	530_C	1.372	0.82
52_A	55_L	1.366	0.82
589_S	600_R	1.359	0.82
493_I	507_L	1.358	0.82
378_N	381_A	1.357	0.81
6_L	9_D	1.353	0.81
184_I	198_F	1.352	0.81
271_N	275_F	1.351	0.81
677_Q	680_E	1.349	0.81
171_V	495_Y	1.333	0.80
56_L	60_F	1.328	0.80
250_A	328_A	1.323	0.80
354_K	451_N	1.322	0.80
226_R	266_Q	1.321	0.80
215_M	277_M	1.321	0.80
217_Y	414_L	1.309	0.79
246_P	255_T	1.306	0.79
531_R	535_S	1.304	0.79
458_A	490_P	1.296	0.78
167_F	209_I	1.296	0.78
637_L	649_L	1.291	0.78
544_A	547_R	1.291	0.78
623_F	654_G	1.287	0.78
670_H	686_L	1.283	0.78
565_V	583_L	1.275	0.77
77_D	80_A	1.266	0.77
661_D	664_E	1.266	0.77
26_N	33_L	1.264	0.77
596_G	600_R	1.264	0.77
685_D	688_R	1.261	0.76
350_Y	412_P	1.261	0.76
33_L	39_Y	1.259	0.76
156_H	205_I	1.255	0.76
28_T	224_M	1.253	0.76
51_P	54_G	1.250	0.76
211_H	281_K	1.249	0.76
588_H	591_V	1.248	0.76
142_Q	197_R	1.245	0.75
325_R	329_E	1.244	0.75
209_I	214_H	1.242	0.75
63_S	90_Y	1.240	0.75
37_L	76_F	1.235	0.75
459_E	490_P	1.234	0.75
443_F	446_M	1.231	0.75
188_R	426_D	1.225	0.74
656_R	691_N	1.223	0.74
166_E	204_P	1.222	0.74
94_G	100_Y	1.220	0.74
425_F	437_T	1.218	0.74
236_Y	418_H	1.211	0.73
143_L	242_P	1.210	0.73
5_R	10_A	1.209	0.73
45_K	291_L	1.209	0.73
670_H	681_A	1.205	0.73
40_R	80_A	1.204	0.73
460_Q	464_I	1.198	0.73
582_L	610_V	1.196	0.72
46_Q	100_Y	1.195	0.72
137_D	195_V	1.194	0.72
245_D	249_A	1.187	0.72
625_V	630_L	1.182	0.72
248_V	254_K	1.180	0.71
119_P	124_Q	1.178	0.71
500_P	503_E	1.177	0.71
148_L	157_L	1.175	0.71
39_Y	100_Y	1.174	0.71
404_K	501_K	1.170	0.71
191_D	202_L	1.167	0.71
3_P	6_L	1.157	0.70
541_A	544_A	1.156	0.70
556_L	562_L	1.154	0.70
268_L	271_N	1.152	0.70
91_G	642_S	1.147	0.69
5_R	16_W	1.144	0.69
44_L	80_A	1.142	0.69
568_L	610_V	1.142	0.69
626_D	629_D	1.141	0.69
27_Q	32_N	1.138	0.69
682_G	685_D	1.136	0.68
141_Q	145_A	1.123	0.68
547_R	638_A	1.118	0.67
148_L	278_G	1.115	0.67
11_Q	15_E	1.111	0.67
174_R	177_P	1.109	0.67
95_L	99_E	1.109	0.67
554_A	604_E	1.109	0.67
562_L	608_L	1.108	0.66
243_G	248_V	1.106	0.66
102_T	120_S	1.101	0.66
203_R	206_Q	1.100	0.66
462_K	466_D	1.100	0.66
278_G	432_G	1.097	0.66
636_A	653_Y	1.096	0.66
288_Q	588_H	1.095	0.66
655_V	665_Y	1.094	0.65
28_T	32_N	1.091	0.65
19_K	232_L	1.089	0.65
48_H	85_L	1.088	0.65
435_L	594_L	1.086	0.65
223_R	227_W	1.084	0.65
60_F	64_L	1.084	0.65
455_F	495_Y	1.079	0.64
6_L	10_A	1.075	0.64
544_A	631_P	1.074	0.64
33_L	108_A	1.074	0.64
45_K	93_P	1.059	0.63
156_H	210_V	1.054	0.63
230_L	234_P	1.054	0.63
41_M	391_S	1.051	0.62
464_I	504_L	1.050	0.62
261_A	411_Y	1.050	0.62
640_L	649_L	1.049	0.62
54_G	651_D	1.047	0.62
101_Q	105_R	1.044	0.62
395_V	615_I	1.043	0.62
368_L	507_L	1.042	0.62
549_A	610_V	1.041	0.62
365_G	490_P	1.040	0.61
228_R	233_D	1.040	0.61
174_R	184_I	1.039	0.61
139_L	239_T	1.037	0.61
232_L	259_I	1.036	0.61
636_A	652_R	1.034	0.61
637_L	640_L	1.031	0.61
86_W	90_Y	1.031	0.61
158_Y	216_P	1.029	0.61
496_K	503_E	1.028	0.61
61_D	68_Q	1.027	0.60
245_D	248_V	1.026	0.60
467_S	605_E	1.025	0.60
297_H	607_T	1.024	0.60
274_Y	617_S	1.021	0.60
670_H	689_Y	1.020	0.60
190_Y	328_A	1.020	0.60
671_A	675_E	1.015	0.60
569_R	668_W	1.009	0.59
423_A	444_L	1.009	0.59
391_S	425_F	1.009	0.59
674_R	681_A	1.008	0.59
542_E	580_Y	1.006	0.59
540_D	544_A	1.006	0.59
60_F	90_Y	1.002	0.59
409_I	417_I	1.001	0.58
551_L	556_L	1.000	0.58
409_I	448_G	0.998	0.58
577_D	668_W	0.997	0.58
417_I	444_L	0.991	0.58
38_L	79_Y	0.988	0.57
161_D	220_S	0.987	0.57
408_V	504_L	0.987	0.57
41_M	79_Y	0.986	0.57
569_R	665_Y	0.981	0.57
389_F	581_T	0.980	0.57
621_F	689_Y	0.980	0.57
368_L	504_L	0.979	0.57
565_V	580_Y	0.975	0.56
144_V	234_P	0.975	0.56
10_A	19_K	0.975	0.56
133_F	144_V	0.975	0.56
9_D	16_W	0.974	0.56
119_P	127_I	0.974	0.56
185_A	627_E	0.973	0.56
638_A	655_V	0.973	0.56
275_F	418_H	0.972	0.56
254_K	321_A	0.970	0.56
665_Y	669_F	0.968	0.56
570_V	581_T	0.968	0.56
341_L	344_A	0.966	0.56
69_Q	86_W	0.965	0.56
595_F	629_D	0.963	0.56
647_E	651_D	0.960	0.55
437_T	606_D	0.959	0.55
137_D	142_Q	0.955	0.55
130_W	219_L	0.954	0.55
134_L	462_K	0.954	0.55
227_W	275_F	0.953	0.55
632_D	636_A	0.953	0.55
68_Q	90_Y	0.952	0.55
128_A	132_A	0.951	0.55
669_F	686_L	0.951	0.55
239_T	385_V	0.950	0.54
217_Y	271_N	0.947	0.54
45_K	49_P	0.945	0.54
581_T	626_D	0.943	0.54
368_L	493_I	0.942	0.54
629_D	652_R	0.940	0.54
142_Q	610_V	0.939	0.54
43_E	47_Q	0.938	0.54
520_D	611_V	0.938	0.54
571_E	577_D	0.936	0.53
177_P	351_L	0.933	0.53
582_L	629_D	0.932	0.53
404_K	467_S	0.928	0.53
62_L	66_R	0.923	0.52
446_M	465_R	0.922	0.52
402_L	509_K	0.921	0.52
60_F	86_W	0.921	0.52
579_V	669_F	0.920	0.52
629_D	632_D	0.920	0.52
23_P	32_N	0.919	0.52
217_Y	227_W	0.918	0.52
108_A	545_L	0.918	0.52
430_N	436_N	0.917	0.52
544_A	634_V	0.916	0.52
590_N	595_F	0.914	0.52
188_R	191_D	0.914	0.52
496_K	507_L	0.912	0.51
297_H	401_E	0.910	0.51
621_F	654_G	0.910	0.51
316_F	417_I	0.909	0.51
443_F	593_S	0.909	0.51
154_L	315_E	0.908	0.51
63_S	66_R	0.908	0.51
605_E	640_L	0.907	0.51
502_R	506_E	0.906	0.51
677_Q	681_A	0.903	0.51
142_Q	241_L	0.903	0.51
123_E	166_E	0.901	0.51
143_L	238_V	0.901	0.51
577_D	581_T	0.897	0.50
685_D	689_Y	0.896	0.50
634_V	642_S	0.895	0.50
567_F	579_V	0.894	0.50
210_V	684_L	0.893	0.50
97_D	101_Q	0.890	0.50
156_H	167_F	0.889	0.50
152_L	267_F	0.889	0.50
78_D	102_T	0.888	0.50
549_A	556_L	0.887	0.49
50_L	94_G	0.886	0.49
253_F	411_Y	0.883	0.49
600_R	620_N	0.880	0.49
107_L	111_A	0.877	0.49
646_Y	649_L	0.876	0.49
349_R	581_T	0.875	0.48
569_R	669_F	0.873	0.48
4_T	9_D	0.872	0.48
196_E	653_Y	0.871	0.48
177_P	220_S	0.869	0.48
393_S	413_L	0.868	0.48
579_V	672_Y	0.866	0.48
639_A	659_D	0.864	0.48
328_A	424_G	0.864	0.48
133_F	145_A	0.863	0.48
402_L	502_R	0.862	0.47
50_L	60_F	0.861	0.47
306_D	373_D	0.860	0.47
573_D	628_S	0.859	0.47
458_A	488_D	0.858	0.47
426_D	430_N	0.857	0.47
28_T	31_A	0.857	0.47
51_P	55_L	0.857	0.47
643_E	690_E	0.856	0.47
291_L	417_I	0.856	0.47
105_R	109_Q	0.855	0.47
92_L	295_N	0.853	0.47
243_G	249_A	0.850	0.46
385_V	598_E	0.850	0.46
242_P	255_T	0.850	0.46
272_A	378_N	0.849	0.46
224_M	228_R	0.849	0.46
181_I	321_A	0.848	0.46
134_L	219_L	0.847	0.46
10_A	16_W	0.845	0.46
11_Q	182_D	0.842	0.46
460_Q	500_P	0.840	0.46
244_Y	256_F	0.836	0.45
310_S	358_Y	0.834	0.45
418_H	423_A	0.833	0.45
190_Y	335_L	0.833	0.45
584_R	588_H	0.833	0.45
631_P	635_D	0.830	0.45
367_T	492_G	0.830	0.45
404_K	594_L	0.830	0.45
41_M	83_H	0.829	0.45
134_L	474_E	0.828	0.45
582_L	608_L	0.828	0.45
120_S	127_I	0.828	0.45
209_I	410_D	0.827	0.45
145_A	230_L	0.825	0.45
157_L	396_K	0.825	0.45
126_Q	255_T	0.824	0.44
109_Q	631_P	0.824	0.44
38_L	107_L	0.823	0.44
177_P	198_F	0.822	0.44
624_D	665_Y	0.821	0.44
48_H	60_F	0.821	0.44
259_I	314_P	0.821	0.44
198_F	202_L	0.820	0.44
512_L	515_V	0.819	0.44
436_N	593_S	0.816	0.44
119_P	123_E	0.813	0.44
154_L	168_F	0.812	0.43
153_F	217_Y	0.810	0.43
49_P	79_Y	0.810	0.43
105_R	108_A	0.809	0.43
162_G	165_G	0.808	0.43
268_L	455_F	0.807	0.43
210_V	683_L	0.805	0.43
103_L	671_A	0.805	0.43
597_E	600_R	0.804	0.43
274_Y	418_H	0.803	0.43
632_D	635_D	0.801	0.43
471_G	589_S	0.800	0.43
42_L	45_K	0.799	0.42
145_A	583_L	0.798	0.42
4_T	7_F	0.798	0.42
23_P	26_N	0.795	0.42
65_D	471_G	0.794	0.42
57_P	85_L	0.793	0.42
199_Y	350_Y	0.793	0.42
274_Y	412_P	0.792	0.42
408_V	627_E	0.791	0.42
107_L	326_L	0.790	0.42
348_N	354_K	0.790	0.42
186_T	233_D	0.790	0.42
386_F	616_G	0.789	0.42
176_P	199_Y	0.789	0.42
568_L	631_P	0.789	0.42
569_R	624_D	0.788	0.42
174_R	185_A	0.788	0.42
551_L	562_L	0.787	0.42
263_S	304_D	0.784	0.41
6_L	16_W	0.784	0.41
624_D	661_D	0.783	0.41
588_H	601_R	0.783	0.41
86_W	354_K	0.782	0.41
37_L	48_H	0.782	0.41
358_Y	412_P	0.781	0.41
7_F	437_T	0.781	0.41
430_N	662_F	0.780	0.41
607_T	680_E	0.779	0.41
161_D	218_A	0.777	0.41
96_S	108_A	0.777	0.41
98_D	224_M	0.775	0.41
444_L	667_D	0.775	0.41
215_M	271_N	0.774	0.41
401_E	550_S	0.773	0.40
236_Y	420_L	0.772	0.40
328_A	440_Y	0.772	0.40
139_L	289_I	0.771	0.40
92_L	689_Y	0.771	0.40
347_Q	443_F	0.769	0.40
58_E	182_D	0.766	0.40
567_F	581_T	0.764	0.40
281_K	418_H	0.764	0.40
284_V	407_W	0.763	0.40
215_M	414_L	0.763	0.40
60_F	85_L	0.761	0.40
45_K	281_K	0.760	0.39
280_I	588_H	0.760	0.39
623_F	650_V	0.760	0.39
504_L	508_L	0.759	0.39
26_N	35_A	0.758	0.39
190_Y	516_L	0.757	0.39
221_D	568_L	0.756	0.39
155_A	277_M	0.755	0.39
520_D	524_R	0.755	0.39
268_L	279_F	0.754	0.39
417_I	441_M	0.754	0.39
38_L	42_L	0.752	0.39
250_A	343_Y	0.749	0.39
263_S	268_L	0.744	0.38
75_E	78_D	0.744	0.38
199_Y	495_Y	0.743	0.38
121_A	496_K	0.742	0.38
441_M	667_D	0.740	0.38
622_F	669_F	0.738	0.38
275_F	525_C	0.737	0.38
121_A	233_D	0.737	0.38
344_A	443_F	0.736	0.38
586_R	591_V	0.736	0.38
116_P	399_V	0.735	0.38
50_L	54_G	0.734	0.37
688_R	691_N	0.734	0.37
332_S	388_H	0.734	0.37
548_L	562_L	0.732	0.37
2_E	321_A	0.732	0.37
497_T	500_P	0.732	0.37
41_M	80_A	0.732	0.37
128_A	134_L	0.731	0.37
437_T	580_Y	0.730	0.37
136_G	385_V	0.727	0.37
62_L	625_V	0.725	0.37
202_L	219_L	0.724	0.37
79_Y	175_T	0.724	0.37
301_F	371_I	0.723	0.37
448_G	611_V	0.723	0.37
398_L	508_L	0.722	0.37
292_N	597_E	0.721	0.37
541_A	627_E	0.721	0.37
158_Y	218_A	0.720	0.36
634_V	638_A	0.719	0.36
329_E	332_S	0.719	0.36
3_P	9_D	0.718	0.36
382_A	398_L	0.718	0.36
257_A	321_A	0.717	0.36
120_S	166_E	0.717	0.36
540_D	630_L	0.716	0.36
566_A	584_R	0.715	0.36
196_E	245_D	0.715	0.36
59_S	604_E	0.714	0.36
196_E	631_P	0.714	0.36
262_R	581_T	0.713	0.36
266_Q	321_A	0.713	0.36
311_V	418_H	0.712	0.36
84_P	87_G	0.711	0.36
53_G	56_L	0.711	0.36
629_D	633_F	0.708	0.36
385_V	448_G	0.706	0.35
134_L	629_D	0.705	0.35
579_V	684_L	0.703	0.35
168_F	216_P	0.703	0.35
3_P	8_I	0.703	0.35
392_A	613_G	0.702	0.35
373_D	378_N	0.701	0.35
273_Q	612_P	0.700	0.35
506_E	510_Q	0.700	0.35
194_G	225_A	0.700	0.35
138_S	234_P	0.700	0.35
464_I	491_T	0.699	0.35
125_A	629_D	0.699	0.35
29_P	32_N	0.698	0.35
36_S	39_Y	0.697	0.35
553_G	556_L	0.696	0.35
347_Q	446_M	0.695	0.35
614_F	672_Y	0.694	0.35
637_L	645_D	0.694	0.35
666_S	670_H	0.693	0.34
581_T	601_R	0.693	0.34
14_A	98_D	0.691	0.34
7_F	206_Q	0.691	0.34
79_Y	208_T	0.691	0.34
332_S	430_N	0.691	0.34
68_Q	584_R	0.690	0.34
552_P	556_L	0.690	0.34
593_S	600_R	0.690	0.34
404_K	455_F	0.687	0.34
470_R	476_L	0.687	0.34
639_A	675_E	0.687	0.34
277_M	281_K	0.686	0.34
622_F	689_Y	0.686	0.34
493_I	503_E	0.684	0.34
371_I	385_V	0.683	0.34
114_P	118_P	0.682	0.34
93_P	107_L	0.682	0.34
636_A	639_A	0.681	0.34
111_A	134_L	0.681	0.34
224_M	324_L	0.680	0.34
413_L	435_L	0.680	0.34
63_S	68_Q	0.679	0.33
548_L	634_V	0.679	0.33
157_L	391_S	0.678	0.33
30_E	79_Y	0.677	0.33
80_A	83_H	0.676	0.33
268_L	448_G	0.676	0.33
382_A	420_L	0.675	0.33
118_P	127_I	0.672	0.33
170_L	630_L	0.672	0.33
35_A	39_Y	0.671	0.33
213_T	617_S	0.671	0.33
300_V	409_I	0.670	0.33
69_Q	73_I	0.670	0.33
322_D	353_A	0.669	0.33
181_I	630_L	0.669	0.33
345_K	633_F	0.668	0.33
299_W	403_P	0.668	0.33
224_M	233_D	0.666	0.33
564_E	591_V	0.666	0.33
347_Q	351_L	0.666	0.33
651_D	656_R	0.665	0.32
299_W	687_N	0.665	0.32
116_P	574_D	0.664	0.32
327_P	440_Y	0.663	0.32
222_A	582_L	0.663	0.32
62_L	85_L	0.662	0.32
33_L	73_I	0.661	0.32
243_G	250_A	0.660	0.32
672_Y	677_Q	0.659	0.32
181_I	208_T	0.659	0.32
102_T	356_D	0.657	0.32
167_F	679_V	0.657	0.32
163_P	199_Y	0.656	0.32
14_A	28_T	0.654	0.32
323_N	353_A	0.654	0.32
544_A	550_S	0.654	0.32
633_F	651_D	0.654	0.32
291_L	441_M	0.653	0.32
141_Q	144_V	0.653	0.32
10_A	17_R	0.650	0.31
52_A	56_L	0.650	0.31
93_P	420_L	0.650	0.31
274_Y	281_K	0.649	0.31
236_Y	281_K	0.647	0.31
38_L	46_Q	0.647	0.31
205_I	513_A	0.647	0.31
350_Y	410_D	0.646	0.31
190_Y	444_L	0.645	0.31
401_E	549_A	0.645	0.31
229_E	270_D	0.644	0.31
547_R	634_V	0.644	0.31
208_T	463_A	0.643	0.31
538_L	541_A	0.642	0.31
279_F	440_Y	0.641	0.31
184_I	191_D	0.641	0.31
425_F	565_V	0.641	0.31
40_R	105_R	0.641	0.31
310_S	354_K	0.641	0.31
399_V	609_T	0.640	0.31
388_H	393_S	0.639	0.31
180_P	353_A	0.639	0.31
76_F	398_L	0.639	0.31
61_D	66_R	0.639	0.31
156_H	213_T	0.639	0.31
204_P	425_F	0.639	0.31
123_E	162_G	0.638	0.31
174_R	183_E	0.638	0.31
467_S	602_D	0.637	0.31
140_K	214_H	0.637	0.31
125_A	192_D	0.637	0.31
40_R	581_T	0.636	0.30
190_Y	331_G	0.635	0.30
167_F	214_H	0.635	0.30
572_D	575_G	0.635	0.30
347_Q	444_L	0.634	0.30
107_L	474_E	0.634	0.30
421_L	433_H	0.633	0.30
154_L	279_F	0.632	0.30
124_Q	625_V	0.632	0.30
124_Q	132_A	0.632	0.30
138_S	471_G	0.632	0.30
663_W	667_D	0.631	0.30
208_T	595_F	0.630	0.30
75_E	655_V	0.630	0.30
333_N	431_V	0.630	0.30
214_H	230_L	0.629	0.30
130_W	145_A	0.629	0.30
82_K	121_A	0.627	0.30
62_L	92_L	0.627	0.30
227_W	268_L	0.627	0.30
440_Y	606_D	0.627	0.30
633_F	653_Y	0.627	0.30
90_Y	533_G	0.626	0.30
250_A	325_R	0.625	0.30
175_T	179_Q	0.624	0.30
26_N	29_P	0.623	0.30
289_I	293_V	0.623	0.30
58_E	174_R	0.622	0.30
26_N	39_Y	0.622	0.30
96_S	369_D	0.622	0.30
158_Y	493_I	0.622	0.30
106_W	110_G	0.621	0.29
168_F	205_I	0.621	0.29
145_A	546_R	0.621	0.29
100_Y	393_S	0.621	0.29
142_Q	198_F	0.619	0.29
144_V	210_V	0.619	0.29
23_P	33_L	0.618	0.29
154_L	280_I	0.617	0.29
420_L	444_L	0.617	0.29
167_F	430_N	0.617	0.29
142_Q	401_E	0.616	0.29
291_L	447_E	0.616	0.29
259_I	413_L	0.615	0.29
21_F	24_V	0.615	0.29
344_A	479_Y	0.615	0.29
217_Y	409_I	0.614	0.29
569_R	577_D	0.614	0.29
281_K	420_L	0.614	0.29
27_Q	31_A	0.614	0.29
393_S	447_E	0.614	0.29
141_Q	228_R	0.614	0.29
11_Q	393_S	0.614	0.29
130_W	253_F	0.613	0.29
409_I	664_E	0.613	0.29
201_R	407_W	0.612	0.29
69_Q	181_I	0.611	0.29
470_R	602_D	0.611	0.29
406_A	501_K	0.610	0.29
453_L	461_R	0.610	0.29
123_E	126_Q	0.610	0.29
123_E	165_G	0.609	0.29
128_A	179_Q	0.608	0.29
300_V	385_V	0.608	0.29
520_D	546_R	0.608	0.29
283_P	292_N	0.608	0.29
432_G	493_I	0.608	0.29
240_A	258_A	0.608	0.29
390_D	687_N	0.606	0.28
75_E	368_L	0.606	0.28
439_L	592_A	0.606	0.28
12_T	377_T	0.605	0.28
299_W	343_Y	0.604	0.28
417_I	423_A	0.604	0.28
86_W	316_F	0.602	0.28
417_I	667_D	0.602	0.28
376_G	515_V	0.601	0.28
188_R	294_I	0.600	0.28
257_A	318_A	0.599	0.28
385_V	512_L	0.598	0.28
190_Y	329_E	0.598	0.28
90_Y	404_K	0.598	0.28
28_T	67_E	0.597	0.28
75_E	107_L	0.596	0.28
426_D	469_Y	0.596	0.28
76_F	354_K	0.595	0.28
308_D	311_V	0.594	0.28
241_L	244_Y	0.593	0.28
288_Q	292_N	0.593	0.28
295_N	591_V	0.593	0.28
280_I	421_L	0.593	0.28
23_P	159_F	0.593	0.28
144_V	263_S	0.593	0.28
544_A	583_L	0.592	0.28
422_V	570_V	0.591	0.28
165_G	658_T	0.591	0.28
156_H	214_H	0.590	0.27
103_L	476_L	0.590	0.27
281_K	291_L	0.590	0.27
276_I	414_L	0.589	0.27
127_I	463_A	0.589	0.27
77_D	180_P	0.589	0.27
236_Y	382_A	0.588	0.27
144_V	233_D	0.587	0.27
217_Y	580_Y	0.587	0.27
113_G	350_Y	0.586	0.27
561_F	643_E	0.586	0.27
373_D	659_D	0.586	0.27
25_L	51_P	0.584	0.27
102_T	105_R	0.584	0.27
600_R	603_P	0.584	0.27
95_L	266_Q	0.583	0.27
655_V	671_A	0.583	0.27
59_S	658_T	0.583	0.27
20_G	428_Y	0.583	0.27
102_T	107_L	0.583	0.27
465_R	630_L	0.582	0.27
292_N	588_H	0.582	0.27
428_Y	432_G	0.582	0.27
324_L	425_F	0.582	0.27
133_F	224_M	0.579	0.27
170_L	202_L	0.579	0.27
96_S	99_E	0.579	0.27
520_D	615_I	0.578	0.27
477_K	482_Y	0.578	0.27
425_F	536_E	0.578	0.27
398_L	406_A	0.577	0.27
367_T	370_L	0.576	0.27
308_D	418_H	0.576	0.27
71_P	86_W	0.575	0.27
345_K	595_F	0.575	0.27
570_V	631_P	0.574	0.26
398_L	512_L	0.573	0.26
255_T	637_L	0.573	0.26
33_L	76_F	0.572	0.26
359_A	489_Q	0.572	0.26
220_S	295_N	0.572	0.26
645_D	651_D	0.571	0.26
7_F	10_A	0.571	0.26
67_E	127_I	0.571	0.26
351_L	355_Q	0.570	0.26
389_F	597_E	0.570	0.26
393_S	615_I	0.570	0.26
101_Q	369_D	0.570	0.26
48_H	71_P	0.569	0.26
522_I	650_V	0.569	0.26
22_F	37_L	0.569	0.26
645_D	648_A	0.569	0.26
668_W	689_Y	0.568	0.26
7_F	316_F	0.568	0.26
292_N	427_V	0.568	0.26
333_N	354_K	0.568	0.26
407_W	593_S	0.568	0.26
672_Y	689_Y	0.567	0.26
168_F	413_L	0.566	0.26
113_G	259_I	0.566	0.26
153_F	168_F	0.565	0.26
205_I	633_F	0.564	0.26
297_H	453_L	0.564	0.26
556_L	586_R	0.564	0.26
42_L	49_P	0.564	0.26
682_G	688_R	0.564	0.26
46_Q	79_Y	0.563	0.26
219_L	223_R	0.563	0.26
217_Y	274_Y	0.563	0.26
526_R	529_P	0.562	0.26
371_I	510_Q	0.562	0.26
291_L	444_L	0.561	0.26
101_Q	607_T	0.560	0.26
303_L	310_S	0.559	0.26
190_Y	306_D	0.559	0.26
56_L	90_Y	0.559	0.26
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288_Q	425_F	0.559	0.26
624_D	669_F	0.558	0.25
13_T	17_R	0.558	0.25
424_G	683_L	0.557	0.25
17_R	21_F	0.557	0.25
120_S	645_D	0.557	0.25
385_V	492_G	0.557	0.25
157_L	660_P	0.557	0.25
59_S	85_L	0.556	0.25
289_I	638_A	0.556	0.25
174_R	548_L	0.556	0.25
142_Q	196_E	0.556	0.25
414_L	418_H	0.555	0.25
289_I	472_A	0.554	0.25
340_W	443_F	0.554	0.25
74_E	122_A	0.554	0.25
475_K	479_Y	0.554	0.25
11_Q	134_L	0.553	0.25
48_H	51_P	0.553	0.25
581_T	627_E	0.553	0.25
682_G	686_L	0.553	0.25
355_Q	491_T	0.552	0.25
630_L	681_A	0.552	0.25
246_P	263_S	0.551	0.25
60_F	79_Y	0.551	0.25
344_A	382_A	0.550	0.25
158_Y	343_Y	0.550	0.25
535_S	540_D	0.549	0.25
256_F	428_Y	0.549	0.25
242_P	256_F	0.549	0.25
209_I	581_T	0.549	0.25
378_N	525_C	0.548	0.25
146_R	151_H	0.548	0.25
154_L	391_S	0.547	0.25
398_L	404_K	0.547	0.25
114_P	117_P	0.547	0.25
366_L	410_D	0.547	0.25
224_M	227_W	0.547	0.25
416_R	447_E	0.546	0.25
7_F	205_I	0.545	0.25
512_L	516_L	0.544	0.25
475_K	594_L	0.544	0.25
509_K	526_R	0.544	0.25
566_A	631_P	0.544	0.25
518_R	521_P	0.544	0.25
636_A	649_L	0.544	0.25
316_F	320_Q	0.543	0.25
91_G	519_R	0.543	0.25
155_A	278_G	0.542	0.25
450_S	588_H	0.542	0.25
332_S	426_D	0.542	0.25
493_I	500_P	0.542	0.25
81_K	301_F	0.542	0.25
268_L	587_A	0.542	0.25
528_G	533_G	0.542	0.25
185_A	581_T	0.542	0.25
238_V	420_L	0.541	0.24
671_A	681_A	0.540	0.24
9_D	17_R	0.540	0.24
499_D	661_D	0.540	0.24
674_R	691_N	0.540	0.24
242_P	378_N	0.540	0.24
491_T	595_F	0.540	0.24
171_V	203_R	0.540	0.24
16_W	21_F	0.539	0.24
197_R	256_F	0.539	0.24
275_F	278_G	0.539	0.24
336_L	681_A	0.539	0.24
424_G	614_F	0.539	0.24
104_A	169_R	0.539	0.24
130_W	133_F	0.539	0.24
640_L	645_D	0.538	0.24
343_Y	491_T	0.538	0.24
178_G	435_L	0.537	0.24
239_T	484_S	0.537	0.24
74_E	117_P	0.536	0.24
112_P	466_D	0.536	0.24
268_L	516_L	0.536	0.24
303_L	312_T	0.536	0.24
47_Q	180_P	0.536	0.24
507_L	510_Q	0.535	0.24
424_G	444_L	0.535	0.24
30_E	85_L	0.534	0.24
227_W	263_S	0.534	0.24
453_L	465_R	0.534	0.24
226_R	453_L	0.534	0.24
136_G	642_S	0.534	0.24
186_T	548_L	0.534	0.24
288_Q	597_E	0.533	0.24
34_Q	39_Y	0.533	0.24
182_D	428_Y	0.533	0.24
358_Y	523_N	0.532	0.24
93_P	441_M	0.532	0.24
48_H	333_N	0.532	0.24
177_P	201_R	0.532	0.24
325_R	630_L	0.532	0.24
439_L	591_V	0.532	0.24
236_Y	311_V	0.532	0.24
2_E	466_D	0.532	0.24
447_E	667_D	0.530	0.24
406_A	512_L	0.530	0.24
321_A	522_I	0.530	0.24
321_A	324_L	0.529	0.24
128_A	671_A	0.529	0.24
444_L	447_E	0.528	0.24
121_A	648_A	0.528	0.24
354_K	443_F	0.528	0.24
564_E	583_L	0.527	0.24
332_S	490_P	0.527	0.24
161_D	411_Y	0.527	0.24
163_P	342_K	0.526	0.24
145_A	373_D	0.526	0.24
61_D	498_D	0.525	0.24
182_D	185_A	0.525	0.24
355_Q	485_A	0.524	0.23
82_K	109_Q	0.524	0.23
650_V	655_V	0.524	0.23
221_D	225_A	0.523	0.23
152_L	407_W	0.523	0.23
487_F	492_G	0.522	0.23
267_F	407_W	0.521	0.23
236_Y	259_I	0.521	0.23
428_Y	633_F	0.520	0.23
201_R	296_D	0.519	0.23
81_K	240_A	0.518	0.23
155_A	230_L	0.517	0.23
202_L	589_S	0.517	0.23
175_T	201_R	0.516	0.23
4_T	16_W	0.516	0.23
123_E	168_F	0.515	0.23
24_V	239_T	0.514	0.23
272_A	275_F	0.514	0.23
653_Y	668_W	0.513	0.23
327_P	433_H	0.512	0.23
233_D	576_K	0.512	0.23
271_N	396_K	0.512	0.23
672_Y	675_E	0.512	0.23
323_N	489_Q	0.511	0.23
499_D	529_P	0.511	0.23
325_R	332_S	0.511	0.23
438_R	469_Y	0.511	0.23
73_I	76_F	0.510	0.23
347_Q	420_L	0.510	0.23
562_L	640_L	0.510	0.23
117_P	239_T	0.510	0.23
518_R	529_P	0.510	0.23
540_D	543_Q	0.510	0.23
59_S	371_I	0.509	0.23
188_R	428_Y	0.509	0.23
392_A	434_Q	0.509	0.23
228_R	642_S	0.507	0.22
279_F	421_L	0.507	0.22
426_D	545_L	0.507	0.22
58_E	595_F	0.507	0.22
41_M	48_H	0.507	0.22
3_P	19_K	0.506	0.22
73_I	243_G	0.506	0.22
79_Y	322_D	0.506	0.22
272_A	380_N	0.506	0.22
504_L	614_F	0.504	0.22
406_A	448_G	0.504	0.22
493_I	602_D	0.504	0.22
409_I	674_R	0.503	0.22
626_D	630_L	0.503	0.22
329_E	424_G	0.502	0.22
564_E	690_E	0.502	0.22
350_Y	450_S	0.502	0.22
13_T	32_N	0.502	0.22
93_P	423_A	0.501	0.22
596_G	599_K	0.501	0.22
324_L	465_R	0.501	0.22
673_Y	684_L	0.501	0.22
412_P	620_N	0.501	0.22
174_R	345_K	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
155cA	1	0.1158	18.4	0.99	Contact Map
1rijA	1	0.0333	18.3	0.99	Contact Map
2ihr1	1	0.0854	17.3	0.99	Contact Map
1gqeA	1	0.097	15.3	0.991	Contact Map
2vpkA	2	0.1664	12.6	0.991	Contact Map
4uzmA	1	0.0767	9.7	0.991	Contact Map
1kb0A	1	0.1447	9.1	0.992	Contact Map
4dncD	1	0.068	7.7	0.992	Contact Map
3gzaA	2	0.0984	7.3	0.992	Contact Map
3riyA	1	0.1302	7	0.992	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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