GREMLIN Database
NapE - Periplasmic nitrate reductase protein NapE
PFAM: PF06796 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 53 (50)
Sequences: 1754 (1013)
Seq/√Len: 143.3
META: 0.856

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
44_Y48_A4.1861.00
39_F43_M3.7621.00
32_A35_G3.0581.00
43_M46_L2.6771.00
21_L26_A2.0111.00
37_Y41_V1.8591.00
10_R13_R1.5511.00
36_G40_L1.4581.00
31_V35_G1.4351.00
35_G39_F1.3941.00
12_R16_R1.3501.00
13_R16_R1.3291.00
31_V34_V1.2641.00
18_F22_T1.2391.00
17_A25_L1.2131.00
9_R13_R1.1711.00
40_L44_Y1.1621.00
43_M47_I1.1290.99
26_A29_L1.0810.99
16_R20_F1.0670.99
20_F24_V1.0460.99
26_A30_A1.0390.99
19_L24_V1.0370.99
30_A33_V1.0330.99
17_A53_P0.9940.98
29_L33_V0.9910.98
41_V45_Q0.9050.97
36_G39_F0.8870.97
32_A36_G0.8800.97
16_R23_V0.8800.97
16_R25_L0.8780.97
22_T26_A0.8420.96
37_Y40_L0.8360.96
17_A26_A0.8320.95
30_A34_V0.8230.95
4_T8_P0.8050.95
4_T7_P0.7890.94
36_G43_M0.7880.94
9_R12_R0.7840.94
20_F47_I0.7740.93
6_D10_R0.7700.93
23_V26_A0.7650.93
7_P53_P0.7480.92
15_L26_A0.7260.91
24_V28_V0.7230.91
5_D8_P0.7200.91
10_R40_L0.7140.90
8_P12_R0.7090.90
19_L22_T0.7020.90
31_V41_V0.6970.89
6_D9_R0.6910.89
18_F53_P0.6870.89
50_P53_P0.6590.86
15_L21_L0.6550.86
4_T9_R0.6300.84
37_Y44_Y0.6290.84
9_R17_A0.6230.83
33_V41_V0.5980.81
17_A24_V0.5850.79
37_Y45_Q0.5840.79
6_D12_R0.5820.79
19_L23_V0.5820.79
24_V37_Y0.5760.78
5_D9_R0.5680.77
28_V45_Q0.5640.77
16_R32_A0.5500.75
31_V36_G0.5500.75
42_W45_Q0.5430.74
33_V36_G0.5400.74
5_D47_I0.5330.73
17_A23_V0.5320.72
46_L50_P0.5230.71
40_L43_M0.5040.68
7_P36_G0.5010.68
7_P10_R0.5000.68
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3pe5A 1 0 14.5 0.868 Contact Map
3owqA 1 0.0189 10.5 0.876 Contact Map
2m8rA 1 0.6981 5.4 0.891 Contact Map
1a91A 1 0.8491 4.8 0.894 Contact Map
4bbjA 1 0.9057 4.3 0.897 Contact Map
3fymA 1 0 4 0.898 Contact Map
4aq5A 1 0.8679 3.7 0.9 Contact Map
3wvfA 1 0 3.6 0.9 Contact Map
2xndJ 3 0.7925 3.6 0.9 Contact Map
3vmtA 1 0.5283 3.6 0.9 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0038 seconds.