GREMLIN Database
TMP_2 - Prophage tail length tape measure protein
PFAM: PF06791 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 205 (200)
Sequences: 1805 (1582)
Seq/√Len: 111.9
META: 0.735

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
71_N74_T3.4201.00
186_A195_F3.2501.00
170_E173_K2.8021.00
181_D184_K2.7171.00
190_N195_F2.4911.00
121_A151_E2.3831.00
8_I12_Q2.3661.00
30_S40_V2.3201.00
161_A171_A2.2791.00
88_Y92_K2.2041.00
27_I40_V2.1391.00
31_L40_V2.1231.00
166_Q174_Q2.1091.00
188_A191_R2.1051.00
198_A202_E2.0601.00
184_K188_A2.0381.00
30_S35_Q2.0361.00
85_A89_Q1.9401.00
81_G84_A1.9281.00
20_L48_L1.9271.00
6_A13_T1.9091.00
98_N107_A1.9021.00
167_D170_E1.8631.00
80_V87_A1.8621.00
155_Q159_D1.8461.00
30_S33_S1.8271.00
177_K188_A1.8271.00
197_T200_Q1.7861.00
32_A39_T1.7831.00
25_T50_D1.7701.00
166_Q171_A1.6221.00
89_Q92_K1.6201.00
25_T29_T1.6121.00
81_G85_A1.6071.00
25_T46_G1.5891.00
136_L154_A1.5861.00
186_A204_I1.5861.00
200_Q203_Q1.5701.00
173_K177_K1.5661.00
182_P189_L1.5541.00
199_A202_E1.5471.00
23_Q26_D1.5411.00
139_L153_A1.4921.00
160_M164_T1.4851.00
177_K180_D1.4481.00
38_L41_L1.4481.00
29_T32_A1.4341.00
157_A171_A1.4201.00
115_L136_L1.4131.00
100_A137_A1.4111.00
59_A62_L1.4041.00
19_Q51_M1.4031.00
187_L191_R1.3961.00
37_P41_L1.3781.00
107_A194_H1.3771.00
142_T145_I1.3711.00
26_D47_Q1.3661.00
116_A121_A1.3271.00
166_Q170_E1.3171.00
44_Q47_Q1.3100.99
190_N201_Y1.3050.99
91_S95_R1.3010.99
116_A133_R1.2890.99
96_A99_K1.2740.99
160_M171_A1.2660.99
22_A25_T1.2650.99
55_V62_L1.2470.99
18_R22_A1.2380.99
84_A88_Y1.2340.99
9_S12_Q1.2280.99
8_I11_K1.2240.99
138_A169_D1.2140.99
23_Q29_T1.2050.99
12_Q15_A1.1970.99
193_Y200_Q1.1910.99
73_L76_A1.1810.99
27_I31_L1.1790.99
187_L192_Q1.1480.99
184_K187_L1.1460.99
138_A141_A1.1350.99
79_A82_A1.1120.98
26_D29_T1.1030.98
123_A129_Q1.1000.98
72_P75_L1.0980.98
188_A192_Q1.0930.98
24_F28_V1.0890.98
56_G60_K1.0810.98
23_Q47_Q1.0790.98
113_G117_D1.0710.98
98_N112_A1.0620.98
134_E138_A1.0600.98
12_Q16_A1.0590.98
16_A21_P1.0510.98
97_F137_A1.0500.98
110_V114_Q1.0470.98
66_L73_L1.0470.98
159_D162_A1.0450.97
131_A134_E1.0450.97
174_Q192_Q1.0400.97
97_F115_L1.0330.97
80_V83_L1.0260.97
185_A189_L1.0230.97
153_A179_L1.0210.97
123_A128_S1.0150.97
87_A94_A1.0110.97
19_Q22_A1.0100.97
135_A138_A1.0040.97
90_G94_A1.0040.97
29_T46_G1.0020.97
7_G13_T0.9950.97
27_I48_L0.9910.97
90_G93_E0.9820.96
95_R98_N0.9800.96
46_G49_K0.9770.96
118_L136_L0.9770.96
78_A81_G0.9760.96
26_D43_Q0.9590.96
112_A121_A0.9440.95
92_K96_A0.9410.95
149_Q152_R0.9390.95
26_D30_S0.9360.95
123_A127_G0.9350.95
130_G134_E0.9280.95
190_N199_A0.9220.95
14_A18_R0.9180.95
118_L151_E0.9180.95
68_G72_P0.9170.95
23_Q43_Q0.9150.95
153_A160_M0.9140.95
168_V175_L0.9120.95
186_A196_L0.9100.94
36_S39_T0.9060.94
10_A13_T0.9020.94
22_A39_T0.8850.94
30_S39_T0.8800.93
114_Q117_D0.8740.93
23_Q30_S0.8680.93
23_Q44_Q0.8670.93
27_I30_S0.8660.93
95_R100_A0.8650.93
11_K14_A0.8630.93
153_A156_A0.8620.93
19_Q23_Q0.8580.93
20_L62_L0.8570.92
105_G114_Q0.8550.92
112_A116_A0.8540.92
71_N75_L0.8540.92
174_Q177_K0.8520.92
16_A22_A0.8510.92
179_L185_A0.8500.92
197_T203_Q0.8490.92
183_V187_L0.8450.92
78_A82_A0.8420.92
97_F133_R0.8270.91
25_T49_K0.8230.91
106_N110_V0.8190.91
83_L87_A0.8120.90
26_D44_Q0.8110.90
78_A85_A0.8100.90
16_A19_Q0.8090.90
48_L51_M0.8070.90
35_Q38_L0.8050.90
151_E155_Q0.7930.89
142_T176_A0.7930.89
15_A19_Q0.7910.89
135_A168_V0.7900.89
33_S39_T0.7900.89
103_L143_G0.7870.89
24_F65_Y0.7860.89
135_A158_L0.7830.89
116_A120_R0.7780.88
7_G10_A0.7780.88
95_R99_K0.7750.88
21_P25_T0.7740.88
12_Q19_Q0.7720.88
147_G151_E0.7660.88
56_G62_L0.7660.88
46_G50_D0.7630.87
91_S96_A0.7580.87
22_A50_D0.7580.87
29_T42_L0.7570.87
77_A83_L0.7530.87
169_D173_K0.7530.87
168_V172_A0.7480.86
133_R137_A0.7480.86
181_D185_A0.7400.86
99_K103_L0.7400.86
77_A81_G0.7390.86
56_G65_Y0.7380.86
146_A149_Q0.7360.85
182_P185_A0.7350.85
22_A26_D0.7320.85
29_T33_S0.7320.85
194_H202_E0.7260.85
122_L125_A0.7240.84
6_A9_S0.7130.84
9_S16_A0.7130.84
128_S131_A0.7120.83
28_V42_L0.7110.83
190_N194_H0.7100.83
49_K57_P0.7100.83
157_A161_A0.7090.83
67_L71_N0.7090.83
132_A136_L0.7060.83
10_A14_A0.7040.83
180_D184_K0.7020.83
110_V151_E0.7010.83
121_A124_A0.6990.82
117_D120_R0.6970.82
17_L20_L0.6930.82
18_R25_T0.6920.82
17_L21_P0.6920.82
65_Y69_L0.6900.82
151_E159_D0.6890.81
145_I149_Q0.6880.81
79_A83_L0.6850.81
139_L145_I0.6840.81
33_S40_V0.6820.81
106_N109_G0.6800.81
87_A97_F0.6770.80
15_A18_R0.6700.80
30_S43_Q0.6700.80
6_A10_A0.6690.79
137_A141_A0.6690.79
136_L140_A0.6630.79
187_L190_N0.6610.79
43_Q47_Q0.6590.78
122_L158_L0.6540.78
96_A100_A0.6520.78
154_A158_L0.6480.77
85_A88_Y0.6460.77
80_V84_A0.6430.77
187_L201_Y0.6330.76
77_A82_A0.6320.76
109_G114_Q0.6320.76
55_V58_A0.6290.75
31_L35_Q0.6270.75
35_Q43_Q0.6250.75
149_Q153_A0.6250.75
30_S36_S0.6210.74
68_G71_N0.6170.74
157_A164_T0.6140.73
37_P40_V0.6110.73
69_L74_T0.6100.73
20_L27_I0.6050.72
69_L72_P0.6050.72
81_G88_Y0.6040.72
13_T17_L0.6010.72
121_A125_A0.5990.72
18_R23_Q0.5920.71
161_A164_T0.5890.70
164_T167_D0.5860.70
115_L118_L0.5850.70
123_A130_G0.5800.69
8_I13_T0.5790.69
61_A64_G0.5790.69
139_L142_T0.5790.69
19_Q36_S0.5780.69
48_L61_A0.5770.69
189_L196_L0.5770.69
5_K8_I0.5670.67
70_I74_T0.5630.67
93_E96_A0.5630.67
82_A85_A0.5580.66
37_P42_L0.5580.66
168_V178_A0.5580.66
22_A29_T0.5550.66
120_R124_A0.5540.66
49_K55_V0.5530.66
195_F201_Y0.5470.65
17_L24_F0.5470.65
87_A91_S0.5460.65
175_L179_L0.5450.64
11_K20_L0.5450.64
98_N104_T0.5450.64
22_A28_V0.5420.64
23_Q27_I0.5410.64
29_T40_V0.5410.64
8_I15_A0.5390.64
21_P24_F0.5390.64
36_S40_V0.5390.64
178_A181_D0.5340.63
122_L154_A0.5340.63
122_L126_T0.5330.63
178_A185_A0.5290.62
147_G152_R0.5280.62
174_Q193_Y0.5270.62
140_A150_F0.5260.62
35_Q40_V0.5260.62
157_A172_A0.5200.61
39_T42_L0.5180.61
198_A201_Y0.5140.60
135_A157_A0.5140.60
58_A61_A0.5110.60
156_A159_D0.5100.59
173_K192_Q0.5060.59
49_K54_G0.5050.59
24_F30_S0.5020.58
196_L201_Y0.5010.58
29_T36_S0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zx6A 2 0.9366 30 0.913 Contact Map
2ch7A 2 0.961 12.2 0.927 Contact Map
1qu7A 2 0.9463 9.7 0.93 Contact Map
4j42A 2 0.4049 9.1 0.931 Contact Map
4q4gX 1 0 7.8 0.933 Contact Map
2nrjA 1 0.7951 7.4 0.934 Contact Map
2wssS 1 0.6439 7.2 0.934 Contact Map
4cgkA 3 0.5073 6.6 0.935 Contact Map
1ciiA 1 0.4634 4.2 0.941 Contact Map
3gwkC 2 0.4732 3.5 0.943 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0075 seconds.