GREMLIN Database
PspB - Phage shock protein B
PFAM: PF06667 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 73 (69)
Sequences: 2697 (1453)
Seq/√Len: 175.0
META: 0.871

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
28_K31_T3.6311.00
10_I13_L2.5011.00
22_I26_I1.9951.00
7_V10_I1.9061.00
20_W24_H1.8561.00
46_L50_A1.8311.00
55_D58_E1.8281.00
65_D71_W1.8201.00
38_E41_K1.8011.00
13_L17_A1.6991.00
11_V14_L1.6891.00
53_L57_I1.6691.00
13_L18_P1.6321.00
65_D72_R1.6211.00
47_W51_R1.6211.00
37_E41_K1.5831.00
64_L71_W1.5751.00
12_F17_A1.5311.00
12_F16_V1.4811.00
60_L64_L1.4641.00
59_T62_R1.4131.00
20_W25_Y1.4011.00
7_V11_V1.3081.00
41_K45_E1.2781.00
16_V25_Y1.2691.00
26_I29_W1.2651.00
19_P22_I1.2431.00
6_F10_I1.1941.00
9_L12_F1.1851.00
45_E49_L1.1851.00
33_A37_E1.1651.00
48_E52_R1.1591.00
57_I60_L1.1421.00
8_P12_F1.0851.00
64_L67_E1.0400.99
39_D42_L1.0130.99
40_E44_E1.0050.99
58_E63_I0.9860.99
49_L54_E0.9620.99
23_L26_I0.9620.99
4_F9_L0.9400.99
18_P21_L0.9200.99
17_A21_L0.9180.99
15_F18_P0.9020.99
18_P22_I0.8990.99
19_P23_L0.8840.98
40_E45_E0.8750.98
33_A36_S0.8700.98
42_L47_W0.8700.98
11_V15_F0.8690.98
57_I65_D0.8520.98
15_F19_P0.8280.97
31_T34_T0.8170.97
51_R55_D0.8140.97
35_L43_L0.8120.97
59_T63_I0.8120.97
60_L68_N0.8030.97
42_L45_E0.7930.97
53_L60_L0.7920.97
23_L28_K0.7450.95
41_K48_E0.7430.95
49_L53_L0.7280.95
14_L19_P0.7240.94
6_F9_L0.7190.94
55_D62_R0.7070.94
12_F18_P0.7010.93
37_E48_E0.6910.93
47_W53_L0.6850.93
44_E63_I0.6770.92
42_L58_E0.6750.92
34_T38_E0.6750.92
54_E58_E0.6730.92
9_L13_L0.6700.92
57_I71_W0.6560.91
63_I71_W0.6510.91
49_L64_L0.6480.91
32_A45_E0.6380.90
60_L65_D0.6320.89
14_L18_P0.6290.89
56_R61_E0.6270.89
42_L54_E0.6240.89
44_E47_W0.6220.89
54_E62_R0.6110.88
37_E57_I0.6070.87
67_E71_W0.6020.87
7_V12_F0.5920.86
15_F20_W0.5870.86
4_F7_V0.5810.85
10_I18_P0.5800.85
32_A38_E0.5770.85
41_K46_L0.5630.83
38_E63_I0.5610.83
47_W68_N0.5570.83
28_K43_L0.5520.82
21_L30_K0.5500.82
68_N72_R0.5440.81
7_V13_L0.5360.80
8_P11_V0.5350.80
65_D68_N0.5270.79
10_I14_L0.5170.78
62_R67_E0.5100.77
5_L27_T0.5020.76
62_R66_A0.5020.76
48_E71_W0.5000.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4bgnA 3 0.5342 74.8 0.786 Contact Map
3rvyA 3 0.3562 70.8 0.792 Contact Map
3pjsK 4 0.9452 70.7 0.793 Contact Map
3effK 4 0.9452 50.3 0.817 Contact Map
4ltoA 3 0.8767 48.4 0.819 Contact Map
4cbcA 3 0.3151 46.1 0.822 Contact Map
3cveA 4 0.5068 36.7 0.832 Contact Map
3layA 5 0.5479 34.1 0.835 Contact Map
4i5sA 2 0.7671 26.7 0.843 Contact Map
2mfrA 1 0.5753 26.6 0.843 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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