GREMLIN Database
FlbD - Flagellar protein (FlbD)
PFAM: PF06289 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 59 (58)
Sequences: 10146 (5702)
Seq/√Len: 748.6
META: 0.925

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_D55_R3.0501.00
20_E36_K3.0041.00
3_K11_E2.5361.00
52_I57_R2.2141.00
5_T42_E2.0961.00
9_G41_R1.8951.00
13_V44_V1.7021.00
24_A44_V1.6811.00
43_S46_E1.6311.00
25_T29_V1.6241.00
18_L33_T1.5801.00
46_E50_R1.5751.00
13_V48_I1.5701.00
31_T37_K1.5261.00
21_T38_L1.4871.00
3_K13_V1.3891.00
49_E53_E1.3431.00
29_V37_K1.3191.00
4_L40_V1.3171.00
29_V39_V1.2291.00
13_V16_A1.1821.00
46_E49_E1.1711.00
49_E57_R1.1511.00
16_A51_V1.1261.00
3_K45_D1.1201.00
53_E57_R1.0861.00
42_E50_R0.9881.00
53_E56_R0.9811.00
13_V51_V0.9751.00
51_V55_R0.9601.00
4_L12_F0.9311.00
5_T11_E0.9281.00
45_D49_E0.9041.00
10_E25_T0.9031.00
17_D52_I0.8681.00
24_A45_D0.8501.00
28_T47_V0.8211.00
24_A43_S0.8211.00
16_A55_R0.8201.00
21_T31_T0.8181.00
22_I44_V0.8161.00
19_I30_I0.8151.00
22_I30_I0.7981.00
30_I40_V0.7931.00
14_L32_L0.7911.00
32_L38_L0.7911.00
42_E46_E0.7831.00
17_D54_Y0.7731.00
23_E37_K0.7721.00
4_L47_V0.7671.00
18_L34_T0.7661.00
6_R23_E0.7541.00
16_A54_Y0.7451.00
50_R53_E0.7421.00
21_T36_K0.7391.00
20_E34_T0.7271.00
18_L32_L0.7191.00
7_L26_P0.7141.00
14_L21_T0.7091.00
55_R58_I0.7051.00
26_P39_V0.7031.00
22_I47_V0.7011.00
49_E52_I0.6991.00
6_R21_T0.6971.00
40_V47_V0.6941.00
6_R10_E0.6871.00
20_E32_L0.6781.00
11_E50_R0.6671.00
25_T37_K0.6651.00
12_F21_T0.6411.00
13_V22_I0.6401.00
14_L30_I0.6401.00
44_V48_I0.6291.00
20_E38_L0.6291.00
3_K50_R0.6281.00
52_I56_R0.6221.00
5_T50_R0.6221.00
48_I52_I0.6121.00
52_I55_R0.5911.00
5_T41_R0.5711.00
21_T34_T0.5261.00
3_K44_V0.5201.00
48_I57_R0.5191.00
7_L41_R0.5131.00
34_T38_L0.5091.00
6_R27_D0.5071.00
15_N18_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4g4kA 1 0.9492 36.1 0.813 Contact Map
3d6wA 3 0.9831 31.3 0.819 Contact Map
4cbvA 2 0.9661 24.7 0.828 Contact Map
2ra2A 3 0.5085 18.9 0.837 Contact Map
2k57A 1 0.4576 16.3 0.842 Contact Map
2jn0A 1 0.4237 16 0.842 Contact Map
2p17A 1 0.6441 14.2 0.846 Contact Map
2rb6A 2 0.5085 12.7 0.85 Contact Map
5ajtA 2 0.9831 11.8 0.852 Contact Map
3bduA 3 0.4407 11.8 0.852 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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