GREMLIN Database
Phage_min_cap2 - Phage minor capsid protein 2
PFAM: PF06152 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 367 (359)
Sequences: 1587 (1371)
Seq/√Len: 72.3
META: 0.778

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
267_A273_P5.1221.00
160_T163_Q5.0921.00
224_V242_Y4.4031.00
316_Y320_Q4.2811.00
332_Q358_L4.2481.00
321_K324_A3.4451.00
324_A328_Q3.2211.00
241_V282_Y3.0921.00
220_D245_S3.0531.00
221_L284_P2.9171.00
149_K171_E2.8891.00
336_L355_L2.8431.00
220_D243_S2.7211.00
153_Q167_R2.6791.00
271_G279_F2.5681.00
207_N271_G2.5431.00
359_Q363_R2.5281.00
174_D335_E2.5231.00
25_I338_A2.5001.00
192_S196_M2.4641.00
188_W196_M2.3791.00
215_E244_I2.3751.00
283_I286_I2.3571.00
189_R192_S2.3311.00
328_Q358_L2.3081.00
323_R326_E2.2761.00
325_L362_Y2.2641.00
90_E213_R2.2251.00
257_P260_S2.1901.00
195_R199_R2.1861.00
62_I65_K2.1501.00
256_Y259_L2.1231.00
336_L352_K2.1211.00
325_L358_L2.1151.00
2_T5_Q2.0451.00
224_V270_L2.0051.00
356_R359_Q1.9811.00
188_W192_S1.9381.00
257_P261_V1.9111.00
262_T270_L1.9071.00
355_L359_Q1.8771.00
336_L348_I1.8681.00
354_K358_L1.8451.00
268_A273_P1.8431.00
262_T265_G1.8091.00
258_L261_V1.8041.00
73_E76_K1.7881.00
208_E211_E1.7841.00
332_Q335_E1.7801.00
221_L241_V1.7761.00
362_Y366_S1.7741.00
329_I333_K1.7561.00
294_D298_E1.7361.00
233_D268_A1.7281.00
348_I352_K1.7271.00
221_L282_Y1.7201.00
314_T317_E1.7121.00
182_Y188_W1.7111.00
181_D187_R1.7051.00
354_K357_E1.6751.00
332_Q355_L1.6401.00
332_Q351_A1.6250.99
323_R330_R1.6080.99
329_I362_Y1.6050.99
233_D236_P1.6040.99
230_A235_A1.6030.99
214_A222_V1.5970.99
263_G266_T1.5830.99
48_K51_E1.5720.99
232_P316_Y1.5700.99
232_P236_P1.5560.99
361_E364_D1.5560.99
257_P262_T1.5350.99
360_A363_R1.5170.99
322_Q326_E1.5160.99
318_A365_F1.5110.99
140_Q144_R1.5000.99
339_A347_D1.4920.99
231_R272_G1.4880.99
220_D246_G1.4820.99
332_Q336_L1.4760.99
224_V279_F1.4660.99
256_Y260_S1.4590.99
27_D31_R1.4580.99
243_S246_G1.4520.99
19_E23_E1.4380.99
335_E351_A1.4190.99
238_Q277_H1.4040.98
358_L362_Y1.4020.98
328_Q332_Q1.3990.98
255_Y258_L1.3990.98
142_A172_L1.3930.98
221_L243_S1.3830.98
178_R187_R1.3770.98
170_K335_E1.3730.98
242_Y258_L1.3630.98
307_K312_E1.3610.98
325_L329_I1.3550.98
259_L262_T1.3460.98
258_L262_T1.3440.98
256_Y262_T1.3320.98
44_W48_K1.3230.98
269_G272_G1.3190.98
359_Q362_Y1.3060.97
225_S277_H1.2990.97
345_K348_I1.2790.97
329_I366_S1.2740.97
226_A238_Q1.2730.97
164_A168_A1.2730.97
271_G278_S1.2680.97
326_E330_R1.2500.97
230_A238_Q1.2310.96
227_H277_H1.2270.96
154_V164_A1.2250.96
246_G249_G1.2190.96
18_E21_E1.2150.96
159_F167_R1.2080.96
180_V188_W1.2070.96
211_E279_F1.2060.96
20_L24_L1.1960.96
340_K348_I1.1960.96
149_K153_Q1.1960.96
246_G251_G1.1920.96
27_D30_R1.1860.96
290_P294_D1.1850.96
196_M273_P1.1740.95
256_Y261_V1.1720.95
213_R216_E1.1630.95
328_Q331_K1.1550.95
117_E121_K1.1500.95
264_Y279_F1.1490.95
252_S255_Y1.1430.95
316_Y319_T1.1400.94
258_L264_Y1.1370.94
250_G255_Y1.1300.94
212_A215_E1.1210.94
200_T204_Q1.1200.94
122_Q132_N1.1120.94
358_L361_E1.1110.94
290_P293_T1.1090.94
303_E306_E1.0990.93
302_E306_E1.0930.93
355_L358_L1.0930.93
296_E300_I1.0840.93
224_V262_T1.0830.93
261_V265_G1.0800.93
242_Y261_V1.0790.93
293_T296_E1.0760.93
122_Q129_N1.0760.93
226_A300_I1.0750.93
39_T42_A1.0750.93
237_W270_L1.0730.92
276_R319_T1.0610.92
47_E51_E1.0550.92
179_T187_R1.0540.92
242_Y270_L1.0540.92
344_D347_D1.0490.92
253_D256_Y1.0480.92
332_Q354_K1.0440.91
242_Y279_F1.0410.91
222_V279_F1.0390.91
222_V270_L1.0380.91
222_V244_I1.0300.91
258_L265_G1.0290.91
24_L177_I1.0240.91
47_E50_Q1.0180.90
324_A358_L1.0160.90
341_A346_E1.0130.90
208_E212_A1.0080.90
5_Q8_A1.0030.90
118_A122_Q1.0010.90
27_D42_A1.0000.90
184_S188_W0.9970.89
242_Y262_T0.9940.89
243_S247_K0.9900.89
20_L63_I0.9890.89
225_S278_S0.9880.89
209_G213_R0.9850.89
310_G313_Y0.9850.89
196_M199_R0.9750.88
335_E339_A0.9710.88
300_I304_E0.9710.88
234_H271_G0.9700.88
189_R334_R0.9690.88
192_S195_R0.9690.88
237_W242_Y0.9660.88
105_P108_E0.9580.87
285_G288_S0.9550.87
30_R45_Q0.9470.87
222_V242_Y0.9440.87
119_L126_D0.9420.87
249_G253_D0.9410.86
357_E361_E0.9360.86
359_Q366_S0.9310.86
30_R42_A0.9290.86
222_V262_T0.9280.86
345_K349_K0.9280.86
119_L123_T0.9270.86
251_G255_Y0.9270.86
249_G252_S0.9270.86
172_L177_I0.9260.86
119_L205_A0.9250.86
193_Y234_H0.9240.85
152_M155_L0.9220.85
141_D145_K0.9210.85
304_E307_K0.9180.85
42_A45_Q0.9160.85
119_L130_L0.9130.85
223_E290_P0.9080.84
258_L279_F0.9060.84
141_D144_R0.9010.84
351_A354_K0.9000.84
243_S257_P0.8990.84
223_E292_Y0.8980.84
356_R360_A0.8970.84
325_L332_Q0.8930.83
115_L119_L0.8920.83
266_T273_P0.8890.83
212_A216_E0.8890.83
347_D350_K0.8850.83
175_S178_R0.8810.83
347_D351_A0.8790.83
330_R333_K0.8760.82
331_K335_E0.8750.82
363_R366_S0.8740.82
113_Q117_E0.8710.82
166_R344_D0.8700.82
325_L328_Q0.8700.82
255_Y259_L0.8690.82
13_I17_Y0.8630.81
19_E149_K0.8630.81
329_I359_Q0.8620.81
322_Q366_S0.8620.81
340_K352_K0.8610.81
69_K74_I0.8600.81
122_Q126_D0.8590.81
126_D148_D0.8580.81
258_L263_G0.8580.81
352_K356_R0.8570.81
137_R141_D0.8570.81
348_I355_L0.8500.80
267_A272_G0.8450.80
322_Q362_Y0.8440.80
310_G314_T0.8410.80
11_D15_E0.8400.80
142_A146_A0.8360.79
227_H276_R0.8360.79
315_G319_T0.8350.79
259_L279_F0.8320.79
60_E74_I0.8310.79
129_N134_T0.8310.79
18_E22_L0.8300.79
313_Y318_A0.8290.79
188_W197_A0.8240.78
323_R333_K0.8240.78
97_K100_G0.8220.78
270_L279_F0.8190.78
262_T272_G0.8180.78
321_K325_L0.8150.77
192_S274_N0.8150.77
90_E217_L0.8140.77
163_Q167_R0.8120.77
223_E289_K0.8100.77
337_A340_K0.8090.77
163_Q166_R0.8060.77
318_A322_Q0.8040.77
227_H238_Q0.8020.76
235_A238_Q0.8010.76
23_E153_Q0.7990.76
258_L270_L0.7950.76
69_K73_E0.7930.76
75_R124_K0.7850.75
130_L133_T0.7840.75
4_E8_A0.7830.75
224_V258_L0.7800.74
355_L363_R0.7800.74
259_L263_G0.7770.74
43_D47_E0.7770.74
299_E303_E0.7760.74
117_E120_I0.7750.74
292_Y297_L0.7750.74
197_A201_G0.7680.73
247_K251_G0.7660.73
191_D195_R0.7660.73
15_E19_E0.7650.73
174_D331_K0.7600.72
231_R242_Y0.7580.72
11_D14_V0.7540.72
145_K149_K0.7530.72
325_L361_E0.7520.72
188_W193_Y0.7520.72
85_G89_D0.7520.72
173_A338_A0.7500.71
236_P268_A0.7450.71
263_G272_G0.7430.71
130_L134_T0.7430.71
242_Y259_L0.7400.70
153_Q159_F0.7370.70
186_R196_M0.7370.70
230_A272_G0.7330.70
12_P15_E0.7310.69
227_H230_A0.7300.69
31_R51_E0.7290.69
13_I77_L0.7260.69
350_K354_K0.7230.69
262_T279_F0.7220.68
210_Q213_R0.7210.68
146_A172_L0.7210.68
31_R42_A0.7140.68
226_A230_A0.7140.68
229_G319_T0.7080.67
261_V264_Y0.7060.67
115_L126_D0.7060.67
295_E299_E0.7060.67
250_G254_K0.6990.66
318_A321_K0.6970.66
261_V270_L0.6960.66
22_L26_A0.6950.66
90_E94_A0.6950.66
30_R39_T0.6940.65
245_S259_L0.6940.65
225_S270_L0.6930.65
299_E302_E0.6930.65
62_I66_L0.6920.65
237_W262_T0.6910.65
231_R237_W0.6900.65
104_I108_E0.6890.65
27_D41_T0.6880.65
353_A357_E0.6870.65
123_T126_D0.6870.65
318_A325_L0.6870.65
188_W327_R0.6840.64
223_E293_T0.6830.64
245_S257_P0.6820.64
231_R273_P0.6810.64
193_Y199_R0.6770.64
322_Q330_R0.6770.64
324_A327_R0.6750.63
15_E18_E0.6750.63
226_A292_Y0.6750.63
31_R35_A0.6740.63
120_I126_D0.6740.63
221_L245_S0.6740.63
214_A281_P0.6740.63
348_I359_Q0.6730.63
58_E73_E0.6730.63
348_I353_A0.6710.63
270_L277_H0.6690.63
42_A47_E0.6690.63
282_Y290_P0.6650.62
115_L127_L0.6650.62
169_V173_A0.6630.62
26_A341_A0.6630.62
247_K257_P0.6630.62
118_A208_E0.6620.62
96_Y100_G0.6620.62
343_G348_I0.6610.62
326_E333_K0.6590.61
351_A355_L0.6570.61
321_K361_E0.6570.61
223_E226_A0.6560.61
269_G273_P0.6540.61
229_G242_Y0.6540.61
5_Q9_L0.6520.61
231_R268_A0.6520.61
264_Y272_G0.6510.60
122_Q208_E0.6510.60
146_A149_K0.6490.60
182_Y186_R0.6490.60
255_Y261_V0.6470.60
64_A71_E0.6470.60
38_G41_T0.6450.60
195_R274_N0.6440.60
231_R265_G0.6420.59
349_K353_A0.6410.59
320_Q323_R0.6390.59
225_S280_Y0.6360.59
55_L143_Y0.6360.59
54_A58_E0.6350.59
322_Q327_R0.6340.58
95_I98_A0.6340.58
27_D59_I0.6320.58
289_K293_T0.6290.58
72_K76_K0.6280.58
220_D247_K0.6270.58
180_V192_S0.6270.58
131_T151_V0.6270.58
210_Q281_P0.6260.58
120_I124_K0.6260.58
295_E300_I0.6260.58
27_D39_T0.6260.58
293_T297_L0.6250.57
262_T269_G0.6250.57
356_R363_R0.6240.57
332_Q362_Y0.6240.57
133_T136_F0.6230.57
304_E312_E0.6210.57
115_L122_Q0.6190.57
229_G315_G0.6190.57
224_V237_W0.6170.56
35_A42_A0.6170.56
321_K365_F0.6160.56
150_A165_I0.6160.56
131_T134_T0.6160.56
260_S265_G0.6140.56
20_L66_L0.6130.56
215_E245_S0.6120.56
233_D263_G0.6120.56
220_D284_P0.6110.56
240_K294_D0.6110.56
265_G269_G0.6110.56
146_A169_V0.6100.56
233_D271_G0.6090.55
333_K355_L0.6080.55
123_T148_D0.6080.55
235_A305_N0.6070.55
64_A67_T0.6070.55
265_G272_G0.6040.55
360_A364_D0.6010.54
222_V258_L0.6000.54
161_Y199_R0.5970.54
154_V198_V0.5960.54
230_A269_G0.5940.54
237_W269_G0.5940.54
29_A338_A0.5940.54
27_D45_Q0.5930.53
336_L358_L0.5910.53
34_K41_T0.5910.53
115_L118_A0.5900.53
229_G305_N0.5870.53
129_N133_T0.5860.53
322_Q329_I0.5860.53
288_S292_Y0.5860.53
339_A344_D0.5860.53
362_Y365_F0.5850.53
355_L362_Y0.5850.53
52_L56_R0.5840.52
16_L66_L0.5830.52
76_K80_E0.5830.52
164_A167_R0.5820.52
282_Y289_K0.5820.52
241_V290_P0.5820.52
224_V271_G0.5820.52
138_P178_R0.5800.52
200_T269_G0.5800.52
197_A200_T0.5790.52
167_R170_K0.5790.52
109_S112_L0.5780.52
108_E111_A0.5770.52
348_I351_A0.5770.52
119_L131_T0.5720.51
48_K52_L0.5710.51
186_R192_S0.5710.51
183_K188_W0.5700.51
71_E75_R0.5700.51
211_E215_E0.5700.51
318_A326_E0.5670.50
214_A282_Y0.5640.50
19_E145_K0.5640.50
226_A297_L0.5600.49
38_G42_A0.5600.49
346_E350_K0.5600.49
238_Q242_Y0.5580.49
75_R120_I0.5570.49
126_D130_L0.5550.49
301_D304_E0.5530.49
24_L59_I0.5510.48
217_L283_I0.5500.48
21_E52_L0.5500.48
126_D129_N0.5490.48
227_H231_R0.5490.48
231_R267_A0.5490.48
234_H272_G0.5480.48
227_H316_Y0.5480.48
288_S291_T0.5460.48
321_K328_Q0.5460.48
63_I74_I0.5450.48
131_T135_A0.5450.48
223_E280_Y0.5440.47
182_Y193_Y0.5430.47
146_A168_A0.5430.47
151_V155_L0.5430.47
211_E244_I0.5410.47
246_G250_G0.5400.47
114_Q117_E0.5400.47
149_K168_A0.5390.47
312_E315_G0.5390.47
31_R45_Q0.5370.47
160_T166_R0.5370.47
4_E7_E0.5370.47
305_N308_V0.5360.46
25_I173_A0.5340.46
222_V257_P0.5340.46
337_A341_A0.5330.46
119_L122_Q0.5320.46
346_E349_K0.5310.46
81_A85_G0.5290.46
168_A194_V0.5270.45
162_N165_I0.5270.45
222_V269_G0.5270.45
161_Y165_I0.5260.45
237_W268_A0.5260.45
262_T266_T0.5260.45
94_A97_K0.5250.45
249_G255_Y0.5250.45
352_K362_Y0.5250.45
244_I247_K0.5240.45
203_N207_N0.5240.45
17_Y21_E0.5240.45
231_R238_Q0.5230.45
56_R60_E0.5220.45
79_E120_I0.5220.45
245_S249_G0.5210.45
322_Q325_L0.5200.45
241_V284_P0.5200.45
6_L10_A0.5200.45
302_E305_N0.5180.44
20_L62_I0.5180.44
223_E242_Y0.5170.44
210_Q223_E0.5160.44
127_L130_L0.5160.44
23_E26_A0.5140.44
28_I43_D0.5140.44
339_A351_A0.5130.44
336_L351_A0.5110.43
67_T74_I0.5110.43
209_G272_G0.5110.43
226_A235_A0.5110.43
244_I258_L0.5100.43
200_T273_P0.5090.43
26_A33_K0.5080.43
139_A180_V0.5070.43
225_S236_P0.5060.43
285_G290_P0.5040.43
116_L120_I0.5020.42
336_L340_K0.5010.42
8_A11_D0.5010.42
166_R170_K0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gd5A 2 0.1853 32.7 0.962 Contact Map
3frtA 1 0.1662 32 0.963 Contact Map
1t3jA 2 0.158 17.8 0.967 Contact Map
1zq1C 1 0 11.3 0.97 Contact Map
3al0B 1 0.4169 10.5 0.97 Contact Map
2g3qA 1 0.1172 9.9 0.97 Contact Map
3ip4B 1 0.4414 9.7 0.971 Contact Map
4zuzA 1 0.2153 9.6 0.971 Contact Map
3sjaC 1 0.1444 8.3 0.971 Contact Map
2zc2A 1 0.188 8.2 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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