TRP - PFAM28P - GREMLIN Contacts

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TRP - Transient receptor potential (TRP) ion channel

PFAM:	PF06011	Sequences: VSWATAVIAGLALLASAVTSGLGHSNTAAHVAANSLSFGDLFGYFQFIAMTGMLSVNYPPIYQAWTSNFAWSMGLINVSFMQDSIDWYRRATGGNPTTLLYSLSTTSVQVKRLDYWSGTGSSSTLVVRGIQRVAFLAGIESTNLFMTGLLFFLIVIAAVVVLVLLFKVILELLARFGWMKKPDRFLDFRNGWGTVLKGILLRLILIGFPQITILCLFQFTQGDSWAAVVLAVVFLALFTGLLGWAAYKVIRIARRSKKMHGNPAYILYDDPETLLKYGFLYNQYRASAYWFFVPLLLYTFVKGIFIGAAQGSGLAQAIGLLIIEVLYLIALSVLRPFMDKSTNVFNILIAVVRVLNVILLLAFVPEFGQPQIVKGVIGVVIIVINAVFTLVLLILILVNAIIALFSKNPDRRYQPMADDRASFIKS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	426 (414)
Sequences:	816 (595)
Seq/√Len:	29.2
META:	0.126

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
134_A	144_L	6.911	1.00
148_G	214_L	4.894	1.00
52_G	66_T	4.426	1.00
401_I	405_F	4.097	1.00
312_S	315_A	3.545	1.00
212_T	303_G	3.385	1.00
81_M	85_I	3.363	1.00
173_L	178_W	3.150	1.00
359_L	377_I	3.030	1.00
32_A	35_S	2.959	1.00
208_F	239_T	2.792	1.00
370_P	373_V	2.761	1.00
164_L	168_V	2.752	1.00
33_A	37_S	2.745	1.00
383_V	387_V	2.684	1.00
186_L	189_R	2.435	0.99
100_L	103_L	2.392	0.99
34_N	37_S	2.331	0.99
300_F	304_I	2.288	0.99
247_Y	251_R	2.251	0.99
17_A	23_G	2.215	0.98
219_F	240_G	2.215	0.98
139_I	147_T	2.202	0.98
190_N	193_G	2.171	0.98
168_V	172_L	2.162	0.98
315_A	319_G	2.154	0.98
185_F	189_R	2.104	0.98
161_V	165_L	2.081	0.97
99_L	102_S	2.057	0.97
291_F	331_L	1.991	0.97
32_A	37_S	1.957	0.96
356_N	385_N	1.936	0.96
229_V	233_V	1.929	0.96
98_T	101_Y	1.922	0.96
185_F	188_F	1.885	0.95
6_A	10_G	1.869	0.95
190_N	194_T	1.865	0.95
167_K	171_E	1.854	0.95
232_V	236_A	1.827	0.95
11_L	15_A	1.814	0.94
171_E	189_R	1.811	0.94
9_A	13_L	1.797	0.94
25_S	29_A	1.772	0.94
133_V	139_I	1.770	0.94
247_Y	253_A	1.746	0.93
225_W	229_V	1.739	0.93
85_I	89_R	1.738	0.93
222_G	228_V	1.726	0.93
89_R	94_G	1.725	0.93
8_I	27_T	1.724	0.93
183_D	188_F	1.721	0.93
189_R	192_W	1.718	0.93
302_K	328_L	1.712	0.92
143_N	147_T	1.696	0.92
332_S	337_F	1.695	0.92
144_L	148_G	1.694	0.92
267_L	281_Y	1.692	0.92
99_L	103_L	1.675	0.92
321_L	358_I	1.672	0.92
16_S	322_I	1.661	0.91
84_S	87_W	1.658	0.91
215_C	307_G	1.653	0.91
124_T	284_Y	1.648	0.91
192_W	198_G	1.629	0.90
395_L	399_N	1.628	0.90
193_G	197_K	1.623	0.90
174_A	177_G	1.594	0.89
305_F	319_G	1.587	0.89
102_S	105_T	1.566	0.89
248_K	251_R	1.560	0.88
239_T	243_G	1.558	0.88
398_V	402_I	1.545	0.88
190_N	197_K	1.536	0.88
89_R	93_G	1.534	0.88
267_L	274_L	1.527	0.87
31_V	35_S	1.526	0.87
272_E	320_L	1.522	0.87
230_L	234_F	1.519	0.87
225_W	228_V	1.519	0.87
94_G	147_T	1.512	0.87
89_R	92_T	1.509	0.87
411_R	415_P	1.495	0.86
159_V	168_V	1.475	0.85
306_I	320_L	1.461	0.85
25_S	28_A	1.454	0.85
31_V	36_L	1.453	0.84
107_S	110_V	1.452	0.84
24_H	28_A	1.445	0.84
219_F	232_V	1.441	0.84
251_R	254_R	1.431	0.84
325_V	329_I	1.417	0.83
250_I	293_V	1.412	0.83
148_G	152_F	1.411	0.83
278_G	281_Y	1.410	0.83
30_H	34_N	1.410	0.83
186_L	190_N	1.404	0.82
331_L	337_F	1.403	0.82
192_W	196_L	1.400	0.82
120_G	123_S	1.392	0.82
304_I	308_A	1.391	0.82
211_I	238_F	1.387	0.82
12_A	20_S	1.386	0.82
4_A	8_I	1.366	0.81
236_A	240_G	1.366	0.81
202_R	278_G	1.362	0.80
234_F	243_G	1.361	0.80
49_A	69_F	1.355	0.80
100_L	104_S	1.352	0.80
21_G	28_A	1.347	0.80
284_Y	337_F	1.345	0.80
86_D	89_R	1.345	0.80
406_S	417_A	1.342	0.79
120_G	124_T	1.340	0.79
111_K	114_D	1.334	0.79
387_V	391_V	1.333	0.79
150_L	159_V	1.324	0.78
79_S	83_D	1.321	0.78
340_K	343_N	1.317	0.78
191_G	195_V	1.312	0.78
191_G	194_T	1.309	0.78
30_H	33_A	1.294	0.77
231_A	244_W	1.292	0.77
391_V	394_I	1.288	0.76
278_G	291_F	1.288	0.76
355_L	359_L	1.278	0.76
57_N	374_K	1.276	0.76
138_G	153_L	1.269	0.75
71_W	310_Q	1.267	0.75
71_W	306_I	1.264	0.75
85_I	150_L	1.263	0.75
196_L	200_L	1.256	0.75
30_H	36_L	1.249	0.74
188_F	194_T	1.249	0.74
239_T	294_P	1.248	0.74
89_R	143_N	1.243	0.74
50_M	317_A	1.242	0.74
394_I	398_V	1.227	0.73
26_N	29_A	1.221	0.72
145_F	148_G	1.221	0.72
369_Q	374_K	1.212	0.72
31_V	34_N	1.210	0.72
230_L	235_L	1.210	0.72
4_A	411_R	1.210	0.72
50_M	213_I	1.201	0.71
198_G	202_R	1.198	0.71
170_L	401_I	1.180	0.70
362_A	377_I	1.172	0.69
195_V	202_R	1.166	0.69
5_T	71_W	1.163	0.69
10_G	72_S	1.155	0.68
324_E	357_V	1.153	0.68
128_R	131_Q	1.150	0.68
99_L	105_T	1.148	0.68
219_F	222_G	1.147	0.68
1_V	4_A	1.147	0.68
75_L	144_L	1.144	0.67
58_Y	62_Y	1.144	0.67
242_L	245_A	1.143	0.67
372_I	376_V	1.140	0.67
82_Q	147_T	1.137	0.67
16_S	24_H	1.137	0.67
232_V	301_V	1.136	0.67
199_I	246_A	1.135	0.67
16_S	158_A	1.133	0.67
328_L	351_V	1.133	0.67
61_I	74_G	1.132	0.67
155_V	164_L	1.131	0.66
411_R	417_A	1.129	0.66
346_N	349_I	1.128	0.66
406_S	415_P	1.127	0.66
216_L	308_A	1.126	0.66
197_K	200_L	1.125	0.66
82_Q	143_N	1.122	0.66
309_A	319_G	1.116	0.65
412_R	418_D	1.116	0.65
52_G	59_P	1.112	0.65
199_I	202_R	1.112	0.65
249_V	254_R	1.108	0.65
194_T	197_K	1.104	0.65
228_V	232_V	1.100	0.64
256_S	284_Y	1.097	0.64
192_W	200_L	1.090	0.64
114_D	119_T	1.089	0.63
176_F	179_M	1.076	0.63
44_Y	385_N	1.074	0.62
184_R	187_D	1.074	0.62
343_N	346_N	1.069	0.62
393_L	412_R	1.068	0.62
40_D	313_G	1.058	0.61
350_A	377_I	1.058	0.61
274_L	281_Y	1.057	0.61
49_A	133_V	1.056	0.61
402_I	406_S	1.056	0.61
136_L	376_V	1.054	0.61
2_S	5_T	1.053	0.61
26_N	31_V	1.050	0.61
139_I	301_V	1.049	0.61
11_L	100_L	1.047	0.60
18_V	23_G	1.047	0.60
100_L	126_V	1.043	0.60
328_L	347_I	1.043	0.60
36_L	216_L	1.040	0.60
159_V	164_L	1.039	0.60
228_V	311_G	1.032	0.59
72_S	218_Q	1.031	0.59
224_S	267_L	1.025	0.59
332_S	347_I	1.025	0.59
166_F	169_I	1.020	0.58
284_Y	295_L	1.018	0.58
406_S	411_R	1.015	0.58
187_D	190_N	1.012	0.58
91_A	94_G	1.006	0.57
75_L	148_G	1.006	0.57
10_G	25_S	1.002	0.57
56_V	364_V	1.001	0.57
32_A	36_L	1.000	0.57
243_G	291_F	1.000	0.57
55_S	357_V	0.993	0.56
19_T	27_T	0.990	0.56
99_L	141_S	0.988	0.56
23_G	26_N	0.983	0.55
184_R	190_N	0.980	0.55
217_F	297_L	0.979	0.55
206_I	317_A	0.977	0.55
298_Y	302_K	0.974	0.55
82_Q	223_D	0.973	0.55
351_V	355_L	0.969	0.54
106_T	111_K	0.968	0.54
281_Y	291_F	0.968	0.54
165_L	168_V	0.967	0.54
63_Q	320_L	0.967	0.54
16_S	23_G	0.960	0.54
352_V	384_I	0.956	0.53
380_V	384_I	0.955	0.53
237_L	306_I	0.953	0.53
411_R	414_Q	0.951	0.53
157_A	161_V	0.951	0.53
332_S	351_V	0.951	0.53
21_G	26_N	0.949	0.53
230_L	245_A	0.945	0.53
17_A	21_G	0.945	0.53
16_S	192_W	0.944	0.52
200_L	203_L	0.939	0.52
307_G	310_Q	0.939	0.52
87_W	91_A	0.938	0.52
144_L	291_F	0.938	0.52
101_Y	104_S	0.935	0.52
71_W	343_N	0.933	0.52
111_K	124_T	0.931	0.51
204_I	276_K	0.931	0.51
12_A	400_A	0.928	0.51
146_M	149_L	0.927	0.51
89_R	327_Y	0.916	0.50
311_G	350_A	0.915	0.50
65_W	69_F	0.914	0.50
140_E	385_N	0.912	0.50
5_T	9_A	0.911	0.50
13_L	17_A	0.910	0.50
167_K	298_Y	0.904	0.49
274_L	278_G	0.902	0.49
410_D	413_Y	0.902	0.49
16_S	28_A	0.900	0.49
14_L	384_I	0.897	0.49
309_A	315_A	0.896	0.49
98_T	103_L	0.896	0.49
355_L	384_I	0.894	0.49
14_L	27_T	0.894	0.49
168_V	171_E	0.889	0.48
13_L	16_S	0.888	0.48
11_L	293_V	0.888	0.48
305_F	323_I	0.887	0.48
145_F	152_F	0.886	0.48
172_L	176_F	0.886	0.48
376_V	379_V	0.883	0.48
113_L	119_T	0.880	0.47
361_L	367_F	0.880	0.47
164_L	170_L	0.874	0.47
145_F	150_L	0.872	0.47
144_L	149_L	0.869	0.47
7_V	368_G	0.869	0.47
52_G	228_V	0.869	0.47
26_N	242_L	0.865	0.46
87_W	93_G	0.863	0.46
169_I	178_W	0.863	0.46
55_S	311_G	0.860	0.46
253_A	267_L	0.859	0.46
242_L	252_I	0.859	0.46
238_F	248_K	0.857	0.46
177_G	181_K	0.857	0.46
21_G	27_T	0.854	0.45
103_L	108_V	0.853	0.45
17_A	22_L	0.852	0.45
19_T	406_S	0.851	0.45
89_R	227_A	0.849	0.45
209_P	310_Q	0.845	0.45
98_T	104_S	0.842	0.44
19_T	28_A	0.841	0.44
10_G	16_S	0.840	0.44
13_L	22_L	0.831	0.44
14_L	337_F	0.830	0.44
152_F	212_T	0.830	0.44
280_L	324_E	0.829	0.43
210_Q	214_L	0.825	0.43
13_L	23_G	0.825	0.43
25_S	170_L	0.821	0.43
35_S	233_V	0.820	0.43
158_A	161_V	0.818	0.43
243_G	247_Y	0.818	0.43
161_V	168_V	0.816	0.42
23_G	28_A	0.814	0.42
407_K	410_D	0.814	0.42
318_I	361_L	0.812	0.42
230_L	233_V	0.811	0.42
205_L	217_F	0.808	0.42
131_Q	397_L	0.808	0.42
20_S	23_G	0.806	0.42
19_T	24_H	0.806	0.42
401_I	406_S	0.805	0.42
285_R	288_A	0.805	0.42
156_I	159_V	0.802	0.41
236_A	401_I	0.801	0.41
10_G	210_Q	0.800	0.41
189_R	205_L	0.797	0.41
16_S	22_L	0.797	0.41
28_A	31_V	0.796	0.41
113_L	325_V	0.792	0.41
223_D	331_L	0.791	0.41
19_T	22_L	0.790	0.40
15_A	371_Q	0.787	0.40
372_I	375_G	0.786	0.40
87_W	94_G	0.782	0.40
404_L	417_A	0.782	0.40
96_P	102_S	0.782	0.40
128_R	268_Y	0.781	0.40
167_K	170_L	0.780	0.40
64_A	74_G	0.780	0.40
290_W	374_K	0.780	0.40
224_S	227_A	0.777	0.40
288_A	375_G	0.777	0.40
330_A	333_V	0.776	0.39
14_L	18_V	0.775	0.39
344_V	347_I	0.775	0.39
324_E	345_F	0.772	0.39
77_N	238_F	0.771	0.39
28_A	235_L	0.771	0.39
412_R	417_A	0.770	0.39
142_T	351_V	0.769	0.39
104_S	200_L	0.766	0.39
290_W	309_A	0.766	0.39
88_Y	94_G	0.764	0.39
149_L	157_A	0.764	0.39
48_I	57_N	0.762	0.38
229_V	326_L	0.760	0.38
300_F	396_I	0.758	0.38
390_L	394_I	0.758	0.38
72_S	76_I	0.756	0.38
13_L	26_N	0.756	0.38
192_W	197_K	0.756	0.38
21_G	24_H	0.755	0.38
219_F	239_T	0.754	0.38
145_F	149_L	0.753	0.38
27_T	30_H	0.752	0.38
88_Y	93_G	0.752	0.38
22_L	29_A	0.752	0.38
54_L	58_Y	0.751	0.38
224_S	296_L	0.750	0.38
197_K	204_I	0.750	0.38
202_R	206_I	0.745	0.37
98_T	102_S	0.742	0.37
190_N	200_L	0.739	0.37
233_V	243_G	0.731	0.36
190_N	195_V	0.729	0.36
302_K	365_P	0.728	0.36
327_Y	352_V	0.727	0.36
25_S	36_L	0.726	0.36
49_A	66_T	0.726	0.36
181_K	184_R	0.726	0.36
195_V	201_L	0.725	0.36
86_D	90_R	0.723	0.36
230_L	244_W	0.722	0.35
41_L	45_F	0.722	0.35
218_Q	353_R	0.721	0.35
73_M	301_V	0.720	0.35
62_Y	364_V	0.719	0.35
33_A	36_L	0.719	0.35
304_I	315_A	0.718	0.35
321_L	325_V	0.718	0.35
208_F	300_F	0.715	0.35
215_C	349_I	0.714	0.35
192_W	392_L	0.711	0.35
16_S	75_L	0.710	0.35
329_I	390_L	0.709	0.35
408_N	412_R	0.708	0.34
300_F	308_A	0.708	0.34
54_L	306_I	0.707	0.34
10_G	155_V	0.707	0.34
185_F	190_N	0.706	0.34
65_W	223_D	0.706	0.34
149_L	165_L	0.705	0.34
130_I	151_F	0.704	0.34
396_I	399_N	0.703	0.34
276_K	286_A	0.703	0.34
15_A	23_G	0.702	0.34
222_G	232_V	0.702	0.34
357_V	390_L	0.700	0.34
19_T	31_V	0.700	0.34
224_S	284_Y	0.699	0.34
292_F	375_G	0.699	0.34
382_I	386_A	0.698	0.34
162_L	234_F	0.698	0.34
18_V	22_L	0.698	0.34
113_L	176_F	0.694	0.33
42_F	305_F	0.692	0.33
196_L	202_R	0.690	0.33
18_V	21_G	0.690	0.33
51_T	302_K	0.689	0.33
165_L	174_A	0.689	0.33
101_Y	144_L	0.688	0.33
253_A	344_V	0.686	0.33
166_F	241_L	0.685	0.33
101_Y	108_V	0.683	0.33
105_T	109_Q	0.683	0.33
309_A	396_I	0.682	0.33
127_V	379_V	0.682	0.33
134_A	404_L	0.679	0.32
40_D	353_R	0.679	0.32
64_A	269_D	0.678	0.32
323_I	326_L	0.677	0.32
252_I	255_R	0.676	0.32
259_M	263_P	0.675	0.32
403_A	417_A	0.674	0.32
160_V	297_L	0.674	0.32
79_S	113_L	0.673	0.32
397_L	400_A	0.672	0.32
154_I	172_L	0.671	0.32
390_L	393_L	0.670	0.32
53_M	73_M	0.669	0.32
40_D	71_W	0.668	0.32
27_T	166_F	0.668	0.32
247_Y	314_L	0.668	0.32
184_R	240_G	0.666	0.32
68_N	74_G	0.665	0.32
119_T	236_A	0.665	0.32
171_E	175_R	0.665	0.32
234_F	238_F	0.662	0.31
159_V	368_G	0.660	0.31
12_A	17_A	0.659	0.31
6_A	9_A	0.659	0.31
301_V	306_I	0.658	0.31
147_T	223_D	0.657	0.31
328_L	335_R	0.654	0.31
17_A	20_S	0.653	0.31
240_G	348_L	0.653	0.31
369_Q	415_P	0.652	0.31
310_Q	343_N	0.652	0.31
198_G	201_L	0.651	0.31
285_R	334_L	0.650	0.30
301_V	304_I	0.647	0.30
106_T	121_S	0.647	0.30
167_K	189_R	0.647	0.30
339_D	380_V	0.646	0.30
153_L	350_A	0.646	0.30
197_K	203_L	0.643	0.30
202_R	274_L	0.643	0.30
193_G	196_L	0.642	0.30
92_T	223_D	0.639	0.30
190_N	205_L	0.638	0.30
140_E	356_N	0.636	0.30
303_G	349_I	0.634	0.29
413_Y	418_D	0.634	0.29
305_F	309_A	0.632	0.29
239_T	323_I	0.632	0.29
296_L	334_L	0.632	0.29
7_V	386_A	0.632	0.29
4_A	18_V	0.631	0.29
268_Y	300_F	0.631	0.29
45_F	69_F	0.631	0.29
345_F	354_V	0.630	0.29
8_I	29_A	0.630	0.29
201_L	288_A	0.629	0.29
49_A	73_M	0.628	0.29
121_S	384_I	0.627	0.29
53_M	72_S	0.627	0.29
403_A	415_P	0.627	0.29
119_T	123_S	0.626	0.29
190_N	411_R	0.626	0.29
83_D	397_L	0.626	0.29
148_G	173_L	0.626	0.29
88_Y	140_E	0.625	0.29
127_V	325_V	0.624	0.29
42_F	317_A	0.623	0.29
266_I	287_S	0.623	0.29
130_I	192_W	0.623	0.29
318_I	366_E	0.622	0.29
64_A	136_L	0.622	0.29
152_F	207_G	0.620	0.29
148_G	210_Q	0.619	0.28
3_W	10_G	0.619	0.28
9_A	25_S	0.619	0.28
157_A	325_V	0.617	0.28
15_A	320_L	0.616	0.28
102_S	122_S	0.616	0.28
97_T	105_T	0.614	0.28
98_T	105_T	0.613	0.28
152_F	168_V	0.612	0.28
81_M	236_A	0.612	0.28
131_Q	134_A	0.608	0.28
22_L	28_A	0.608	0.28
26_N	30_H	0.608	0.28
311_G	315_A	0.607	0.28
143_N	146_M	0.605	0.28
155_V	295_L	0.604	0.28
151_F	154_I	0.604	0.28
157_A	284_Y	0.602	0.27
360_L	364_V	0.601	0.27
252_I	348_L	0.601	0.27
174_A	179_M	0.600	0.27
170_L	241_L	0.599	0.27
82_Q	94_G	0.596	0.27
68_N	147_T	0.594	0.27
169_I	348_L	0.594	0.27
254_R	258_K	0.592	0.27
256_S	262_N	0.591	0.27
85_I	92_T	0.590	0.27
144_L	302_K	0.589	0.27
196_L	209_P	0.589	0.27
144_L	152_F	0.589	0.27
162_L	241_L	0.587	0.26
73_M	207_G	0.587	0.26
13_L	27_T	0.585	0.26
169_I	190_N	0.584	0.26
51_T	57_N	0.583	0.26
56_V	163_V	0.583	0.26
137_A	165_L	0.580	0.26
328_L	354_V	0.580	0.26
107_S	111_K	0.579	0.26
318_I	398_V	0.579	0.26
224_S	242_L	0.578	0.26
304_I	322_I	0.576	0.26
375_G	382_I	0.574	0.26
112_R	315_A	0.573	0.26
71_W	274_L	0.572	0.26
6_A	21_G	0.569	0.25
25_S	53_M	0.567	0.25
106_T	240_G	0.567	0.25
347_I	359_L	0.565	0.25
102_S	351_V	0.564	0.25
212_T	238_F	0.564	0.25
75_L	223_D	0.564	0.25
10_G	303_G	0.563	0.25
360_L	371_Q	0.563	0.25
121_S	161_V	0.560	0.25
62_Y	66_T	0.559	0.25
45_F	389_T	0.558	0.25
275_L	329_I	0.558	0.25
320_L	324_E	0.555	0.25
268_Y	282_N	0.554	0.25
257_K	262_N	0.553	0.24
55_S	146_M	0.553	0.24
226_A	284_Y	0.552	0.24
121_S	130_I	0.552	0.24
407_K	411_R	0.549	0.24
285_R	331_L	0.546	0.24
165_L	297_L	0.546	0.24
184_R	194_T	0.545	0.24
164_L	284_Y	0.544	0.24
85_I	88_Y	0.544	0.24
212_T	296_L	0.544	0.24
243_G	311_G	0.543	0.24
170_L	179_M	0.543	0.24
163_V	167_K	0.542	0.24
192_W	195_V	0.541	0.24
298_Y	324_E	0.539	0.24
211_I	284_Y	0.538	0.24
211_I	296_L	0.538	0.24
363_F	378_G	0.538	0.24
173_L	179_M	0.537	0.24
61_I	376_V	0.536	0.23
280_L	351_V	0.535	0.23
350_A	365_P	0.534	0.23
189_R	214_L	0.534	0.23
114_D	329_I	0.534	0.23
390_L	398_V	0.534	0.23
401_I	404_L	0.532	0.23
28_A	326_L	0.531	0.23
97_T	364_V	0.528	0.23
2_S	237_L	0.527	0.23
325_V	332_S	0.526	0.23
104_S	172_L	0.525	0.23
36_L	107_S	0.524	0.23
95_N	323_I	0.524	0.23
18_V	165_L	0.523	0.23
73_M	214_L	0.523	0.23
200_L	365_P	0.523	0.23
339_D	383_V	0.522	0.23
162_L	309_A	0.522	0.23
106_T	114_D	0.522	0.23
69_F	145_F	0.517	0.22
121_S	359_L	0.516	0.22
184_R	188_F	0.516	0.22
96_P	215_C	0.516	0.22
239_T	250_I	0.515	0.22
105_T	119_T	0.515	0.22
219_F	308_A	0.515	0.22
158_A	176_F	0.513	0.22
149_L	154_I	0.513	0.22
139_I	148_G	0.512	0.22
213_I	344_V	0.512	0.22
183_D	189_R	0.510	0.22
355_L	369_Q	0.509	0.22
166_F	348_L	0.509	0.22
15_A	270_D	0.508	0.22
114_D	391_V	0.507	0.22
151_F	305_F	0.507	0.22
301_V	311_G	0.506	0.22
17_A	29_A	0.506	0.22
341_S	402_I	0.504	0.22
361_L	391_V	0.502	0.22
1_V	111_K	0.502	0.22
285_R	327_Y	0.502	0.22
121_S	348_L	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2kncB	1	0.1385	34	0.965	Contact Map
2m20A	2	0.1033	8.1	0.973	Contact Map
2kncA	1	0.1268	7.2	0.974	Contact Map
2l8sA	1	0.108	4.3	0.977	Contact Map
1scfA	4	0	4.1	0.977	Contact Map
2kluA	1	0.1221	3	0.978	Contact Map
2k1eA	3	0.2418	2.8	0.979	Contact Map
2micA	2	0.0939	2.7	0.979	Contact Map
3hd6A	3	0.1033	2.6	0.979	Contact Map
2l9uA	2	0.0869	2.5	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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