GREMLIN Database
Self-incomp_S1 - Plant self-incompatibility protein S1
PFAM: PF05938 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 104 (103)
Sequences: 1588 (1299)
Seq/√Len: 128.0
META: 0.064

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_H24_D3.8571.00
43_N47_T3.4111.00
75_C79_C3.2941.00
64_D67_K2.5381.00
89_Y101_C2.3401.00
100_K103_P2.3271.00
54_F65_V2.2271.00
8_L14_L2.2031.00
31_P34_Q2.1331.00
83_A88_I2.1251.00
3_H35_S2.0841.00
19_K51_F1.9721.00
16_V28_H1.9161.00
7_D82_S1.8921.00
20_S50_F1.8801.00
20_S23_D1.8341.00
42_P66_Y1.8331.00
7_D84_R1.7591.00
54_F88_I1.7341.00
3_H37_S1.7291.00
23_D48_T1.6811.00
49_L64_D1.6421.00
86_D89_Y1.6081.00
42_P68_A1.5541.00
25_L50_F1.5511.00
14_L54_F1.4761.00
21_K49_L1.4651.00
23_D40_F1.4171.00
9_G85_E1.3771.00
15_T27_V1.3721.00
3_H80_I1.3681.00
14_L83_A1.3601.00
15_T29_V1.3381.00
25_L28_H1.3061.00
13_P29_V1.2961.00
13_P31_P1.2791.00
16_V36_F1.2661.00
21_K51_F1.2090.99
19_K49_L1.1800.99
23_D50_F1.1710.99
53_S60_H1.1140.99
12_K85_E1.0880.99
5_T80_I1.0740.99
53_S62_S1.0460.98
71_D74_R1.0280.98
51_F62_S1.0070.98
28_H36_F1.0020.98
83_A89_Y0.9990.98
86_D100_K0.9970.98
10_N32_P0.9840.98
9_G12_K0.9670.97
17_H26_G0.9630.97
20_S40_F0.9440.97
72_D75_C0.9440.97
47_T68_A0.9390.97
30_L34_Q0.9370.97
17_H25_L0.9270.97
54_F101_C0.9160.96
91_F94_D0.9060.96
22_D48_T0.9050.96
51_F64_D0.9030.96
97_P100_K0.8980.96
20_S48_T0.8980.96
27_V55_W0.8940.96
92_N95_N0.8930.96
74_R90_L0.8880.96
7_D33_G0.8840.96
4_I36_F0.8810.95
25_L48_T0.8760.95
22_D40_F0.8630.95
4_I54_F0.8590.95
46_G68_A0.8490.94
54_F83_A0.8320.94
82_S98_W0.8230.93
84_R89_Y0.8180.93
9_G32_P0.8140.93
91_F98_W0.7910.92
12_K59_K0.7760.91
12_K56_W0.7600.90
90_L93_N0.7550.90
19_K24_D0.7520.90
30_L36_F0.7510.90
28_H39_S0.7500.90
22_D50_F0.7300.89
12_K57_G0.7140.88
40_F66_Y0.7120.87
17_H20_S0.7090.87
49_L53_S0.7060.87
38_F50_F0.7040.87
84_R87_G0.7030.87
19_K62_S0.6970.86
14_L81_W0.6880.86
8_L56_W0.6840.85
16_V30_L0.6660.84
41_R45_F0.6660.84
24_D79_C0.6630.83
92_N98_W0.6610.83
99_E102_Y0.6590.83
19_K64_D0.6590.83
55_W60_H0.6550.83
21_K48_T0.6480.82
75_C78_L0.6380.81
37_S41_R0.6340.81
66_Y94_D0.6330.80
49_L67_K0.6290.80
12_K32_P0.6280.80
63_F66_Y0.6250.80
6_N52_C0.6240.80
42_P73_D0.6190.79
25_L36_F0.6170.79
25_L40_F0.6130.78
98_W102_Y0.6080.78
5_T35_S0.5980.77
94_D98_W0.5950.76
5_T82_S0.5920.76
69_K77_K0.5900.76
4_I38_F0.5890.76
72_D76_G0.5870.75
73_D76_G0.5850.75
7_D92_N0.5820.75
30_L85_E0.5750.74
74_R99_E0.5710.73
29_V83_A0.5700.73
17_H48_T0.5650.73
98_W101_C0.5640.72
19_K53_S0.5630.72
15_T36_F0.5610.72
96_G99_E0.5560.71
54_F89_Y0.5550.71
43_N48_T0.5540.71
78_L93_N0.5500.71
63_F88_I0.5480.70
36_F85_E0.5450.70
29_V77_K0.5410.69
43_N66_Y0.5410.69
42_P45_F0.5400.69
6_N18_C0.5380.69
33_G55_W0.5290.68
90_L101_C0.5280.67
13_P57_G0.5260.67
46_G69_K0.5250.67
51_F54_F0.5250.67
20_S25_L0.5220.67
89_Y100_K0.5190.66
61_H81_W0.5160.66
10_N82_S0.5120.65
70_R74_R0.5110.65
71_D75_C0.5110.65
9_G33_G0.5110.65
13_P32_P0.5100.65
65_V70_R0.5070.64
92_N97_P0.5040.64
76_G93_N0.5020.64
92_N96_G0.5000.63
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c75A 1 0.6058 42.3 0.87 Contact Map
2ov0A 1 0.6058 31.3 0.879 Contact Map
4knuA 3 0.8365 28.3 0.882 Contact Map
3cvbA 1 0.6442 26 0.884 Contact Map
3wkqA 3 0.9808 22 0.888 Contact Map
1id2A 1 0.6058 20.1 0.89 Contact Map
2xu9A 1 0.8462 18.8 0.891 Contact Map
3ziyA 3 0.9808 18.6 0.891 Contact Map
2aanA 2 0.6346 18.3 0.892 Contact Map
3gdcA 3 0.9904 17.9 0.892 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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