GREMLIN Database
GvpO - Gas vesicle synthesis protein GvpO
PFAM: PF05800 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 93 (86)
Sequences: 2616 (1748)
Seq/√Len: 188.5
META: 0.838

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
47_R71_E3.1621.00
38_G49_T2.7271.00
37_S67_S2.4081.00
47_R69_E2.3801.00
56_R60_D2.3681.00
71_E80_G2.2361.00
51_E87_Y2.1981.00
12_L17_A1.9571.00
14_A39_L1.9241.00
40_E82_R1.7201.00
60_D63_D1.7051.00
15_A27_E1.6561.00
56_R63_D1.6271.00
73_D77_E1.6081.00
32_E56_R1.5951.00
49_T67_S1.5801.00
40_E47_R1.5521.00
57_R62_T1.5201.00
15_A19_R1.4691.00
88_R91_Q1.4681.00
42_T71_E1.4561.00
20_R24_Q1.4421.00
42_T47_R1.4351.00
64_V92_A1.4291.00
58_I61_T1.3911.00
63_D89_R1.3811.00
54_E66_A1.3671.00
19_R27_E1.3641.00
13_S16_E1.3421.00
34_E53_V1.3281.00
40_E80_G1.3011.00
18_A22_R1.2641.00
53_V65_L1.2551.00
55_L60_D1.2291.00
13_S77_E1.2071.00
26_A33_P1.2031.00
18_A39_L1.1951.00
21_A26_A1.1911.00
25_L29_T1.1731.00
49_T69_E1.1681.00
41_R74_D1.1651.00
31_R52_V1.1501.00
34_E63_D1.1491.00
7_R10_G1.0791.00
25_L81_Y1.0761.00
58_I62_T1.0281.00
55_L61_T0.9970.99
55_L62_T0.9880.99
37_S51_E0.9850.99
69_E82_R0.9750.99
62_T88_R0.9750.99
24_Q77_E0.9640.99
19_R23_E0.9450.99
29_T52_V0.9360.99
12_L20_R0.9260.99
17_A72_L0.9150.99
69_E84_T0.9080.99
42_T45_G0.8950.99
26_A32_E0.8890.99
21_A72_L0.8650.98
31_R35_S0.8540.98
51_E67_S0.8480.98
7_R74_D0.8470.98
88_R92_A0.8450.98
36_V50_V0.8370.98
25_L50_V0.8350.98
22_R33_P0.8210.98
17_A30_G0.8160.98
20_R72_L0.8030.98
64_V88_R0.8020.98
55_L64_V0.7810.97
47_R82_R0.7650.97
61_T91_Q0.7570.97
33_P52_V0.7340.96
73_D79_L0.7310.96
67_S85_R0.7290.96
15_A24_Q0.7260.96
55_L66_A0.7230.95
25_L70_V0.7150.95
13_S27_E0.7130.95
70_V82_R0.6940.94
60_D90_G0.6910.94
64_V90_G0.6910.94
18_A38_G0.6830.94
82_R85_R0.6830.94
48_V63_D0.6690.93
48_V72_L0.6670.93
17_A41_R0.6580.93
19_R22_R0.6570.93
22_R30_G0.6500.92
22_R72_L0.6440.92
31_R56_R0.6400.92
34_E67_S0.6360.91
34_E62_T0.6220.90
17_A48_V0.6210.90
23_E27_E0.6140.90
7_R11_R0.6100.90
29_T50_V0.6090.90
16_E20_R0.6080.89
21_A78_L0.5980.89
16_E19_R0.5900.88
49_T66_A0.5740.87
68_Y89_R0.5740.87
11_R74_D0.5600.85
79_L84_T0.5570.85
59_P62_T0.5560.85
9_R12_L0.5530.85
53_V61_T0.5530.85
40_E65_L0.5520.84
22_R92_A0.5500.84
54_E83_R0.5470.84
34_E37_S0.5470.84
8_S11_R0.5410.83
21_A48_V0.5370.83
55_L58_I0.5360.83
18_A21_A0.5350.83
81_Y91_Q0.5280.82
20_R23_E0.5280.82
40_E49_T0.5260.81
40_E92_A0.5240.81
21_A41_R0.5230.81
34_E52_V0.5230.81
38_G48_V0.5220.81
22_R36_V0.5170.80
50_V70_V0.5120.80
22_R37_S0.5110.80
50_V80_G0.5050.79
25_L68_Y0.5020.78
51_E60_D0.5000.78
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1jnsA 1 0.5914 26 0.887 Contact Map
4exrA 2 0.828 25.3 0.888 Contact Map
3tc5A 1 0.5699 24.2 0.889 Contact Map
2mntA 1 0.5699 23.2 0.89 Contact Map
2pv1A 1 0.5914 23.1 0.89 Contact Map
1yw5A 1 0.5699 22.6 0.891 Contact Map
2lj4A 1 0.5699 19.1 0.894 Contact Map
1j6yA 1 0.5699 17.9 0.896 Contact Map
4tnsA 1 0.5699 17.3 0.897 Contact Map
3i6cA 1 0.5699 15.4 0.899 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0048 seconds.