Glyco_transf_90 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Glyco_transf_90 - Glycosyl transferase family 90

PFAM:	PF05686	Sequences: SSPTCPDYFRWIHEDLRPWKETGITREMVERAKRTAGFRYVIVNGKLYVEKYGKSFQTRDVFTLWGILQLLRKYPGRLPDLELMFNCGDWPVVPKKDYRGPNAAPPPLFSYCGDDDTLDIVFPDWSFWGWPEINIGPWDLLLKSIKEGNKRVPWEDKEPYAFWRGNPTVAETRLDLLKCNRSDPDLWDARITKQDWDTESKPGFKESSLEDQCKYKYKIYIEGVAWSVRLKYLLACDSVVLKVKPEYYEFFYRGLKPWQHYWPVKRDDDCSDLKEAVDWGNEHDEEAQAIAKAGSDFIRENLKMDYVYCYMFHLLNEYAKLLKFKPTVPPGAVEVCSESMACPAEGLEKKFMMESMVKSPSDTSPCTLPPPYDPAELKAFLERKENSIRQVEKWE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	395 (333)
Sequences:	680 (451)
Seq/√Len:	24.7
META:	0.121

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
283_H	286_E	5.700	1.00
213_C	236_C	3.886	1.00
29_V	324_F	3.791	1.00
46_K	334_E	3.325	1.00
86_N	110_S	3.186	1.00
39_R	82_E	3.112	1.00
155_E	288_Q	2.821	0.99
317_E	320_K	2.798	0.99
159_P	216_K	2.795	0.99
229_R	233_L	2.707	0.99
16_L	314_L	2.585	0.99
81_L	315_L	2.524	0.99
157_K	237_D	2.464	0.99
88_G	224_V	2.429	0.98
44_N	80_D	2.344	0.98
37_G	88_G	2.328	0.98
90_W	224_V	2.259	0.97
265_K	272_D	2.177	0.97
241_L	280_G	2.149	0.97
113_G	248_Y	2.140	0.96
208_S	211_D	2.101	0.96
43_V	80_D	2.088	0.96
319_A	322_L	2.076	0.96
147_E	150_K	2.073	0.96
23_G	323_K	2.068	0.96
175_D	269_D	2.044	0.95
239_V	287_A	2.041	0.95
144_S	210_E	2.036	0.95
279_W	283_H	2.007	0.95
231_K	236_C	1.994	0.95
324_F	331_G	1.944	0.94
239_V	285_E	1.938	0.94
110_S	119_D	1.907	0.93
280_G	287_A	1.893	0.93
47_L	71_L	1.883	0.93
6_P	9_F	1.869	0.93
129_G	132_E	1.858	0.92
7_D	10_R	1.850	0.92
213_C	222_E	1.841	0.92
141_L	145_I	1.835	0.92
312_F	316_N	1.835	0.92
162_F	207_S	1.828	0.92
84_M	108_L	1.827	0.92
91_P	225_A	1.817	0.91
222_E	242_K	1.800	0.91
46_K	335_V	1.791	0.91
157_K	239_V	1.789	0.91
237_D	295_S	1.789	0.91
169_V	249_E	1.788	0.91
161_A	219_I	1.775	0.90
159_P	281_N	1.774	0.90
233_L	249_E	1.769	0.90
216_K	284_D	1.765	0.90
158_E	211_D	1.738	0.89
113_G	117_T	1.729	0.89
40_Y	47_L	1.709	0.89
88_G	110_S	1.705	0.89
17_R	335_V	1.682	0.88
285_E	317_E	1.677	0.88
40_Y	49_V	1.657	0.87
61_V	68_L	1.653	0.87
80_D	325_K	1.640	0.86
153_P	156_D	1.632	0.86
114_D	117_T	1.609	0.85
262_W	280_G	1.607	0.85
121_V	248_Y	1.605	0.85
5_C	15_D	1.597	0.85
213_C	231_K	1.591	0.85
46_K	73_K	1.582	0.84
236_C	250_F	1.546	0.83
329_P	332_A	1.532	0.82
237_D	292_K	1.532	0.82
259_Q	293_A	1.526	0.82
227_S	231_K	1.522	0.82
303_K	306_Y	1.500	0.81
19_W	23_G	1.491	0.81
289_A	293_A	1.481	0.80
239_V	302_L	1.428	0.78
234_L	251_F	1.423	0.77
194_Q	207_S	1.418	0.77
29_V	293_A	1.416	0.77
5_C	16_L	1.416	0.77
8_Y	25_T	1.413	0.77
292_K	296_D	1.390	0.76
173_R	176_L	1.384	0.75
286_E	289_A	1.373	0.75
43_V	325_K	1.365	0.74
192_T	215_Y	1.363	0.74
221_I	243_V	1.347	0.73
94_P	97_D	1.341	0.73
282_E	285_E	1.339	0.73
11_W	15_D	1.336	0.73
108_L	289_A	1.335	0.73
256_K	259_Q	1.332	0.72
128_W	236_C	1.325	0.72
82_E	309_C	1.324	0.72
297_F	302_L	1.314	0.71
222_E	236_C	1.310	0.71
86_N	224_V	1.307	0.71
83_L	160_Y	1.304	0.71
46_K	271_S	1.303	0.71
145_I	211_D	1.286	0.70
91_P	110_S	1.277	0.69
296_D	300_E	1.274	0.69
265_K	271_S	1.272	0.69
242_K	245_P	1.272	0.69
86_N	91_P	1.264	0.68
211_D	214_K	1.254	0.68
223_G	227_S	1.247	0.67
186_L	189_A	1.244	0.67
268_D	271_S	1.238	0.67
121_V	153_P	1.226	0.66
154_W	284_D	1.226	0.66
112_C	247_Y	1.223	0.66
256_K	284_D	1.206	0.65
62_F	70_L	1.198	0.64
110_S	169_V	1.195	0.64
186_L	192_T	1.186	0.63
21_E	323_K	1.180	0.63
115_D	285_E	1.179	0.63
131_P	191_I	1.178	0.63
69_Q	72_R	1.172	0.62
173_R	189_A	1.165	0.62
82_E	324_F	1.154	0.61
47_L	335_V	1.152	0.61
333_V	337_S	1.150	0.61
46_K	150_K	1.148	0.61
56_F	191_I	1.140	0.60
91_P	119_D	1.139	0.60
4_T	293_A	1.134	0.60
255_L	273_L	1.129	0.59
141_L	144_S	1.128	0.59
168_T	224_V	1.119	0.59
17_R	327_T	1.117	0.59
23_G	127_F	1.116	0.58
246_E	327_T	1.115	0.58
113_G	302_L	1.111	0.58
227_S	236_C	1.107	0.58
47_L	198_T	1.105	0.58
56_F	224_V	1.101	0.57
141_L	273_L	1.081	0.56
30_E	282_E	1.079	0.56
50_E	331_G	1.073	0.55
110_S	249_E	1.069	0.55
65_W	69_Q	1.067	0.55
6_P	12_I	1.067	0.55
257_P	261_Y	1.057	0.54
17_R	330_P	1.053	0.54
165_G	173_R	1.047	0.54
180_N	189_A	1.046	0.54
14_E	17_R	1.044	0.53
64_L	70_L	1.043	0.53
239_V	280_G	1.040	0.53
80_D	87_C	1.039	0.53
297_F	301_N	1.038	0.53
12_I	297_F	1.036	0.53
210_E	272_D	1.029	0.52
32_A	225_A	1.028	0.52
189_A	273_L	1.026	0.52
41_V	50_E	1.025	0.52
27_E	31_R	1.001	0.50
89_D	123_P	0.993	0.50
66_G	69_Q	0.991	0.50
48_Y	108_L	0.987	0.49
212_Q	311_M	0.986	0.49
283_H	288_Q	0.981	0.49
264_V	276_A	0.980	0.49
77_R	93_V	0.979	0.49
139_D	204_F	0.978	0.49
183_D	274_K	0.972	0.48
268_D	272_D	0.970	0.48
95_K	118_L	0.970	0.48
71_L	75_P	0.960	0.47
207_S	277_V	0.959	0.47
113_G	245_P	0.957	0.47
176_L	264_V	0.956	0.47
56_F	193_K	0.956	0.47
115_D	330_P	0.954	0.47
269_D	272_D	0.952	0.47
82_E	331_G	0.949	0.47
188_D	191_I	0.947	0.46
42_I	67_I	0.943	0.46
19_W	22_T	0.942	0.46
41_V	328_V	0.942	0.46
256_K	267_D	0.940	0.46
235_A	297_F	0.938	0.46
67_I	319_A	0.937	0.46
244_K	265_K	0.936	0.46
279_W	286_E	0.931	0.45
240_V	294_G	0.928	0.45
122_F	314_L	0.926	0.45
224_V	267_D	0.925	0.45
128_W	213_C	0.924	0.45
179_C	187_W	0.924	0.45
88_G	221_I	0.922	0.45
222_E	228_V	0.917	0.44
16_L	109_F	0.913	0.44
12_I	15_D	0.913	0.44
41_V	109_F	0.904	0.43
265_K	269_D	0.904	0.43
59_R	71_L	0.901	0.43
197_D	201_K	0.898	0.43
176_L	189_A	0.898	0.43
232_Y	236_C	0.894	0.43
177_L	191_I	0.888	0.42
13_H	317_E	0.887	0.42
131_P	236_C	0.883	0.42
88_G	114_D	0.881	0.42
132_E	232_Y	0.881	0.42
186_L	190_R	0.877	0.41
3_P	328_V	0.874	0.41
260_H	263_P	0.874	0.41
3_P	267_D	0.872	0.41
29_V	34_R	0.870	0.41
287_A	291_A	0.867	0.41
15_D	120_I	0.867	0.41
213_C	250_F	0.865	0.41
151_R	273_L	0.864	0.41
11_W	14_E	0.863	0.40
229_R	249_E	0.861	0.40
184_P	187_W	0.859	0.40
18_P	26_R	0.858	0.40
239_V	268_D	0.858	0.40
220_Y	226_W	0.856	0.40
110_S	224_V	0.855	0.40
58_T	61_V	0.855	0.40
33_K	44_N	0.855	0.40
130_W	221_I	0.853	0.40
166_N	229_R	0.850	0.40
90_W	113_G	0.850	0.40
122_F	129_G	0.850	0.40
3_P	21_E	0.847	0.39
270_C	280_G	0.846	0.39
4_T	7_D	0.843	0.39
124_D	163_W	0.843	0.39
23_G	26_R	0.843	0.39
31_R	80_D	0.843	0.39
296_D	330_P	0.841	0.39
194_Q	225_A	0.840	0.39
4_T	325_K	0.837	0.39
128_W	231_K	0.836	0.39
124_D	228_V	0.833	0.38
234_L	294_G	0.832	0.38
33_K	46_K	0.832	0.38
173_R	180_N	0.826	0.38
10_R	13_H	0.824	0.38
46_K	155_E	0.824	0.38
39_R	332_A	0.821	0.38
162_F	218_K	0.820	0.37
166_N	226_W	0.819	0.37
324_F	327_T	0.818	0.37
9_F	253_R	0.817	0.37
74_Y	281_N	0.812	0.37
213_C	247_Y	0.805	0.36
66_G	129_G	0.798	0.36
236_C	247_Y	0.795	0.36
93_V	108_L	0.794	0.36
161_A	264_V	0.791	0.36
49_V	110_S	0.790	0.35
49_V	171_E	0.785	0.35
198_T	244_K	0.783	0.35
105_P	326_P	0.781	0.35
176_L	219_I	0.781	0.35
111_Y	130_W	0.779	0.35
297_F	331_G	0.777	0.35
184_P	192_T	0.774	0.34
283_H	323_K	0.773	0.34
24_I	296_D	0.773	0.34
153_P	157_K	0.772	0.34
86_N	119_D	0.770	0.34
213_C	227_S	0.768	0.34
25_T	292_K	0.768	0.34
126_S	231_K	0.768	0.34
3_P	330_P	0.764	0.34
145_I	208_S	0.760	0.34
320_K	323_K	0.758	0.33
125_W	228_V	0.753	0.33
244_K	267_D	0.752	0.33
211_D	278_D	0.752	0.33
28_M	78_L	0.752	0.33
107_P	119_D	0.751	0.33
222_E	226_W	0.750	0.33
231_K	249_E	0.749	0.33
243_V	291_A	0.746	0.33
4_T	331_G	0.745	0.33
47_L	305_D	0.744	0.33
128_W	311_M	0.744	0.33
4_T	14_E	0.741	0.32
98_Y	106_P	0.740	0.32
38_F	87_C	0.739	0.32
4_T	116_D	0.739	0.32
222_E	232_Y	0.735	0.32
86_N	90_W	0.734	0.32
130_W	232_Y	0.730	0.32
82_E	90_W	0.730	0.32
327_T	331_G	0.728	0.32
42_I	114_D	0.727	0.31
11_W	19_W	0.723	0.31
140_L	145_I	0.722	0.31
164_R	223_G	0.721	0.31
213_C	226_W	0.719	0.31
118_L	323_K	0.718	0.31
288_Q	315_L	0.718	0.31
164_R	188_D	0.717	0.31
56_F	168_T	0.717	0.31
7_D	268_D	0.714	0.31
59_R	213_C	0.714	0.31
234_L	242_K	0.713	0.31
85_F	308_Y	0.712	0.31
4_T	78_L	0.711	0.30
275_E	330_P	0.709	0.30
155_E	285_E	0.709	0.30
270_C	273_L	0.708	0.30
167_P	249_E	0.707	0.30
77_R	316_N	0.706	0.30
65_W	70_L	0.706	0.30
205_K	215_Y	0.705	0.30
136_G	181_R	0.705	0.30
267_D	271_S	0.704	0.30
126_S	225_A	0.702	0.30
239_V	262_W	0.700	0.30
37_G	53_G	0.700	0.30
110_S	172_T	0.699	0.30
41_V	82_E	0.699	0.30
68_L	219_I	0.698	0.30
163_W	229_R	0.697	0.30
131_P	142_L	0.696	0.30
188_D	298_I	0.696	0.30
90_W	225_A	0.696	0.30
43_V	328_V	0.696	0.30
90_W	121_V	0.695	0.29
67_I	295_S	0.692	0.29
179_C	321_L	0.690	0.29
17_R	255_L	0.689	0.29
277_V	280_G	0.688	0.29
122_F	127_F	0.687	0.29
86_N	294_G	0.686	0.29
37_G	224_V	0.686	0.29
242_K	252_Y	0.685	0.29
73_K	284_D	0.683	0.29
56_F	88_G	0.682	0.29
143_K	147_E	0.682	0.29
234_L	255_L	0.677	0.28
58_T	70_L	0.676	0.28
145_I	254_G	0.675	0.28
44_N	48_Y	0.674	0.28
226_W	231_K	0.671	0.28
64_L	69_Q	0.670	0.28
27_E	331_G	0.668	0.28
293_A	327_T	0.668	0.28
168_T	193_K	0.667	0.28
44_N	278_D	0.666	0.28
322_L	326_P	0.666	0.28
3_P	211_D	0.665	0.28
213_C	249_E	0.665	0.28
319_A	324_F	0.664	0.28
225_A	236_C	0.663	0.28
77_R	335_V	0.662	0.28
103_A	268_D	0.661	0.27
109_F	219_I	0.660	0.27
125_W	307_V	0.660	0.27
111_Y	124_D	0.660	0.27
252_Y	255_L	0.660	0.27
5_C	8_Y	0.659	0.27
64_L	72_R	0.657	0.27
108_L	314_L	0.656	0.27
115_D	292_K	0.656	0.27
129_G	133_I	0.655	0.27
46_K	274_K	0.655	0.27
160_Y	188_D	0.654	0.27
219_I	233_L	0.652	0.27
177_L	275_E	0.652	0.27
16_L	235_A	0.651	0.27
268_D	292_K	0.651	0.27
26_R	325_K	0.651	0.27
239_V	259_Q	0.648	0.27
192_T	252_Y	0.648	0.27
107_P	318_Y	0.648	0.27
94_P	335_V	0.647	0.27
14_E	288_Q	0.646	0.27
180_N	184_P	0.644	0.27
68_L	112_C	0.642	0.26
6_P	10_R	0.637	0.26
154_W	279_W	0.637	0.26
21_E	268_D	0.636	0.26
16_L	270_C	0.635	0.26
161_A	216_K	0.634	0.26
59_R	159_P	0.632	0.26
81_L	322_L	0.631	0.26
104_A	335_V	0.628	0.26
62_F	69_Q	0.627	0.26
226_W	249_E	0.625	0.25
229_R	309_C	0.622	0.25
109_F	162_F	0.622	0.25
42_I	244_K	0.620	0.25
163_W	222_E	0.618	0.25
329_P	334_E	0.616	0.25
47_L	115_D	0.616	0.25
241_L	263_P	0.613	0.25
268_D	293_A	0.608	0.25
69_Q	74_Y	0.608	0.25
93_V	251_F	0.607	0.25
162_F	252_Y	0.605	0.24
29_V	334_E	0.605	0.24
130_W	213_C	0.605	0.24
135_I	209_L	0.604	0.24
27_E	272_D	0.603	0.24
294_G	299_R	0.603	0.24
174_L	224_V	0.602	0.24
214_K	296_D	0.602	0.24
98_Y	251_F	0.599	0.24
26_R	155_E	0.598	0.24
115_D	248_Y	0.595	0.24
109_F	322_L	0.594	0.24
195_D	264_V	0.594	0.24
193_K	197_D	0.593	0.24
168_T	294_G	0.592	0.24
172_T	252_Y	0.590	0.24
20_K	289_A	0.589	0.24
69_Q	212_Q	0.589	0.24
273_L	282_E	0.588	0.24
82_E	319_A	0.586	0.23
6_P	13_H	0.586	0.23
21_E	104_A	0.583	0.23
7_D	273_L	0.583	0.23
218_K	229_R	0.582	0.23
262_W	287_A	0.581	0.23
251_F	310_Y	0.581	0.23
20_K	26_R	0.580	0.23
131_P	168_T	0.580	0.23
302_L	337_S	0.579	0.23
151_R	211_D	0.576	0.23
297_F	322_L	0.576	0.23
143_K	267_D	0.576	0.23
180_N	188_D	0.573	0.23
71_L	297_F	0.573	0.23
107_P	302_L	0.571	0.23
51_K	78_L	0.568	0.22
10_R	273_L	0.568	0.22
94_P	114_D	0.566	0.22
66_G	70_L	0.565	0.22
127_F	232_Y	0.565	0.22
181_R	190_R	0.564	0.22
239_V	245_P	0.564	0.22
27_E	188_D	0.560	0.22
127_F	231_K	0.560	0.22
139_D	225_A	0.559	0.22
205_K	239_V	0.559	0.22
207_S	287_A	0.558	0.22
115_D	267_D	0.558	0.22
59_R	69_Q	0.558	0.22
124_D	236_C	0.556	0.22
220_Y	240_V	0.556	0.22
131_P	213_C	0.555	0.22
42_I	81_L	0.550	0.22
242_K	337_S	0.549	0.22
124_D	249_E	0.548	0.21
226_W	229_R	0.546	0.21
244_K	263_P	0.544	0.21
114_D	246_E	0.544	0.21
23_G	321_L	0.543	0.21
262_W	308_Y	0.542	0.21
7_D	17_R	0.541	0.21
163_W	249_E	0.541	0.21
157_K	214_K	0.540	0.21
111_Y	132_E	0.540	0.21
296_D	319_A	0.540	0.21
236_C	243_V	0.539	0.21
109_F	314_L	0.538	0.21
23_G	28_M	0.538	0.21
161_A	270_C	0.535	0.21
7_D	259_Q	0.533	0.21
172_T	335_V	0.532	0.21
178_K	193_K	0.530	0.21
153_P	267_D	0.529	0.21
11_W	245_P	0.527	0.20
141_L	237_D	0.527	0.20
213_C	228_V	0.525	0.20
213_C	233_L	0.525	0.20
224_V	268_D	0.524	0.20
130_W	236_C	0.522	0.20
109_F	321_L	0.518	0.20
31_R	47_L	0.517	0.20
9_F	15_D	0.516	0.20
13_H	20_K	0.515	0.20
23_G	315_L	0.514	0.20
15_D	19_W	0.513	0.20
32_A	106_P	0.513	0.20
266_R	335_V	0.512	0.20
150_K	319_A	0.511	0.20
35_T	51_K	0.511	0.20
46_K	149_N	0.509	0.20
113_G	242_K	0.509	0.20
174_L	244_K	0.507	0.20
122_F	249_E	0.507	0.20
163_W	234_L	0.506	0.20
56_F	61_V	0.506	0.20
46_K	319_A	0.505	0.19
125_W	128_W	0.502	0.19
63_T	85_F	0.500	0.19

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4x7rA	1	0.5595	30.9	0.976	Contact Map
3qhpA	1	0.3949	29.7	0.976	Contact Map
2x6qA	1	0.6405	29.3	0.976	Contact Map
4bfcA	3	0.443	23	0.978	Contact Map
4dgwB	1	0.2127	22.8	0.978	Contact Map
3c48A	2	0.7696	12.4	0.98	Contact Map
5c8hA	1	0.2481	12.1	0.98	Contact Map
2g8lA	2	0.3342	11.7	0.98	Contact Map
3oy2A	2	0.7165	11.6	0.98	Contact Map
1p4wA	1	0.0608	10.8	0.981	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.