CLPTM1 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CLPTM1 - Cleft lip and palate transmembrane protein 1 (CLPTM1)

PFAM:	PF05602	Sequences: LILRAFVIYFISSFFMKYFFGKKPPPCPTSDPSCYTSYLPAAPLWPKGTPLDLYVYLSEKSNESLVWKEKNFTYGDWSDGREIDLTIKVPESVQNNGTLYAHVFVTKSGASPDPSDPNYDPAKAVHFTKPLTKYLPKKKVRKTKNLLGGEEETEEEEEEEEEEKDEIVSHWHPNLTLNLVPDFTVYPYGQLPPPLRQYIRLTGQNGWYYPILFVNDFWQLRSDLIPINETVTELPLTITYSPLSLWKFQLYASMDESFKQQAQLGFSGSEIDEVKRILLETNPYLLGLTIVVSILHSVFEFLAFKNDISFWRKKKSLVGLSVRSILWNVFSQLIIFLYLLDNENTSWMILISQGIGLLIEAWKITKAVDVRIRRDPPGSLPRIVFEDKHLSETESKTKEYDELAFKYLSYVLYPLLIGYAVYSLLY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	426 (423)
Sequences:	623 (474)
Seq/√Len:	23.1
META:	0.164

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
330_F	334_I	10.782	1.00
336_F	354_G	5.537	1.00
89_V	234_L	4.896	1.00
171_W	236_L	4.723	1.00
417_I	421_V	4.222	1.00
285_L	288_L	4.099	1.00
355_I	359_I	4.061	1.00
290_I	294_I	3.902	1.00
295_L	299_F	3.702	1.00
301_F	355_I	3.558	1.00
114_P	119_Y	3.204	1.00
336_F	340_L	3.100	1.00
84_D	237_T	2.882	0.99
290_I	293_S	2.856	0.99
273_E	276_R	2.786	0.99
222_S	276_R	2.729	0.99
86_T	233_E	2.477	0.98
413_Y	420_A	2.469	0.98
392_E	395_S	2.349	0.97
85_L	236_L	2.334	0.97
328_N	360_E	2.320	0.97
15_F	19_F	2.300	0.97
49_T	107_K	2.247	0.97
306_N	320_L	2.216	0.96
369_D	386_E	2.197	0.96
276_R	280_E	2.169	0.96
145_N	148_G	2.137	0.96
109_G	114_P	2.045	0.94
369_D	388_K	2.044	0.94
160_E	291_V	2.034	0.94
351_I	355_I	2.028	0.94
215_N	275_K	2.026	0.94
95_N	169_S	2.018	0.94
51_L	179_L	1.979	0.93
317_L	367_A	1.971	0.93
59_E	90_P	1.919	0.92
178_N	243_L	1.913	0.92
232_T	417_I	1.899	0.92
406_K	410_Y	1.885	0.91
339_L	346_S	1.877	0.91
56_Y	65_L	1.851	0.91
314_K	320_L	1.804	0.89
51_L	74_Y	1.796	0.89
339_L	353_Q	1.795	0.89
180_V	243_L	1.791	0.89
43_P	74_Y	1.781	0.89
18_Y	22_K	1.764	0.88
135_L	334_I	1.755	0.88
296_H	299_F	1.754	0.88
311_W	366_K	1.750	0.88
396_K	399_E	1.740	0.88
348_M	352_S	1.740	0.88
8_I	15_F	1.722	0.87
397_T	401_D	1.717	0.87
94_Q	169_S	1.715	0.87
299_F	305_K	1.674	0.86
53_L	105_V	1.674	0.86
112_P	171_W	1.672	0.85
172_H	405_F	1.662	0.85
156_E	159_E	1.659	0.85
305_K	309_S	1.654	0.85
339_L	350_L	1.654	0.85
10_F	14_F	1.643	0.84
17_K	32_P	1.627	0.84
87_I	145_N	1.626	0.84
95_N	229_E	1.606	0.83
89_V	93_V	1.595	0.83
418_G	421_V	1.590	0.82
294_I	298_V	1.585	0.82
6_F	10_F	1.581	0.82
215_N	251_Y	1.570	0.82
111_S	116_D	1.565	0.81
88_K	233_E	1.557	0.81
415_L	420_A	1.542	0.80
2_I	6_F	1.532	0.80
405_F	416_L	1.531	0.80
172_H	219_Q	1.519	0.79
5_A	9_Y	1.519	0.79
288_L	292_V	1.515	0.79
25_P	28_P	1.502	0.79
8_I	14_F	1.494	0.78
178_N	275_K	1.479	0.77
243_L	251_Y	1.470	0.77
15_F	18_Y	1.465	0.77
105_V	274_V	1.461	0.77
101_A	175_L	1.454	0.76
150_E	153_T	1.451	0.76
310_F	320_L	1.448	0.76
308_I	398_K	1.446	0.76
109_G	112_P	1.444	0.76
294_I	297_S	1.438	0.75
289_T	293_S	1.438	0.75
213_F	330_F	1.435	0.75
327_W	331_S	1.429	0.75
407_Y	411_V	1.414	0.74
90_P	93_V	1.413	0.74
133_K	216_D	1.404	0.74
342_N	352_S	1.401	0.73
16_M	20_F	1.400	0.73
369_D	380_L	1.398	0.73
192_P	249_Q	1.395	0.73
58_S	102_H	1.390	0.73
146_L	307_D	1.382	0.72
146_L	338_Y	1.379	0.72
147_L	424_L	1.367	0.72
217_F	347_W	1.367	0.72
9_Y	13_S	1.363	0.71
97_G	132_T	1.359	0.71
300_E	352_S	1.354	0.71
23_K	33_S	1.352	0.71
220_L	275_K	1.339	0.70
169_S	227_I	1.319	0.69
99_L	411_V	1.317	0.69
23_K	27_C	1.315	0.69
178_N	406_K	1.314	0.69
248_F	320_L	1.310	0.68
326_L	364_I	1.286	0.67
86_T	199_I	1.280	0.66
182_D	299_F	1.278	0.66
55_V	238_I	1.271	0.66
180_V	211_I	1.265	0.65
132_T	169_S	1.264	0.65
14_F	18_Y	1.259	0.65
395_S	398_K	1.258	0.65
172_H	224_L	1.239	0.64
87_I	336_F	1.236	0.64
13_S	17_K	1.234	0.64
375_D	382_R	1.234	0.64
404_A	419_Y	1.230	0.63
273_E	277_I	1.230	0.63
111_S	114_P	1.227	0.63
74_Y	182_D	1.223	0.63
320_L	352_S	1.222	0.63
29_T	212_L	1.220	0.63
9_Y	12_S	1.211	0.62
258_F	261_Q	1.204	0.62
332_Q	339_L	1.200	0.61
52_D	56_Y	1.199	0.61
192_P	410_Y	1.191	0.61
370_V	385_F	1.191	0.61
341_D	366_K	1.186	0.60
405_F	412_L	1.184	0.60
265_G	280_E	1.181	0.60
304_F	359_I	1.181	0.60
305_K	308_I	1.179	0.60
8_I	12_S	1.176	0.60
311_W	321_S	1.173	0.59
305_K	311_W	1.172	0.59
310_F	318_V	1.166	0.59
37_S	40_P	1.164	0.59
177_L	213_F	1.164	0.59
324_S	367_A	1.156	0.58
274_V	277_I	1.155	0.58
43_P	314_K	1.154	0.58
31_D	56_Y	1.154	0.58
335_I	350_L	1.154	0.58
269_S	293_S	1.151	0.58
131_L	236_L	1.138	0.57
144_K	276_R	1.138	0.57
151_E	155_E	1.133	0.57
106_T	112_P	1.129	0.57
266_F	352_S	1.128	0.56
4_R	11_I	1.119	0.56
215_N	218_W	1.115	0.56
299_F	306_N	1.114	0.55
70_K	152_E	1.110	0.55
96_N	134_Y	1.107	0.55
236_L	372_I	1.099	0.54
87_I	105_V	1.095	0.54
246_W	249_Q	1.085	0.53
412_L	420_A	1.083	0.53
320_L	366_K	1.082	0.53
310_F	395_S	1.082	0.53
371_R	386_E	1.077	0.53
355_I	391_S	1.077	0.53
292_V	323_R	1.072	0.53
75_G	180_V	1.071	0.53
35_Y	38_Y	1.069	0.52
255_D	336_F	1.063	0.52
30_S	417_I	1.062	0.52
171_W	234_L	1.057	0.52
24_P	27_C	1.053	0.51
320_L	412_L	1.051	0.51
113_D	116_D	1.050	0.51
6_F	34_C	1.050	0.51
228_N	235_P	1.046	0.51
46_P	49_T	1.042	0.50
409_S	413_Y	1.038	0.50
372_I	381_P	1.036	0.50
228_N	234_L	1.035	0.50
219_Q	224_L	1.034	0.50
18_Y	26_P	1.030	0.50
152_E	199_I	1.030	0.50
16_M	19_F	1.028	0.50
11_I	34_C	1.028	0.50
82_E	237_T	1.027	0.49
175_L	384_V	1.027	0.49
305_K	408_L	1.025	0.49
12_S	15_F	1.020	0.49
3_L	402_E	1.020	0.49
19_F	23_K	1.008	0.48
23_K	28_P	1.003	0.48
82_E	239_T	0.999	0.47
198_Y	248_F	0.994	0.47
205_N	335_I	0.992	0.47
185_V	378_G	0.989	0.47
212_L	229_E	0.989	0.47
28_P	34_C	0.989	0.47
300_E	322_V	0.987	0.47
146_L	341_D	0.981	0.46
31_D	421_V	0.980	0.46
310_F	390_L	0.978	0.46
212_L	377_P	0.977	0.46
180_V	245_L	0.976	0.46
31_D	34_C	0.971	0.46
150_E	250_L	0.967	0.45
23_K	26_P	0.966	0.45
414_P	422_Y	0.964	0.45
292_V	299_F	0.963	0.45
6_F	12_S	0.960	0.45
327_W	353_Q	0.957	0.45
30_S	33_S	0.957	0.45
296_H	310_F	0.953	0.44
10_F	13_S	0.949	0.44
8_I	17_K	0.948	0.44
135_L	221_R	0.946	0.44
197_Q	256_E	0.946	0.44
411_V	425_L	0.944	0.44
303_A	307_D	0.943	0.44
119_Y	190_Q	0.941	0.43
303_A	321_S	0.939	0.43
218_W	404_A	0.936	0.43
180_V	294_I	0.934	0.43
141_R	278_L	0.933	0.43
94_Q	232_T	0.931	0.43
76_D	79_D	0.929	0.43
177_L	214_V	0.929	0.43
368_V	385_F	0.927	0.43
172_H	186_Y	0.923	0.42
7_V	11_I	0.920	0.42
400_Y	403_L	0.910	0.41
199_I	250_L	0.910	0.41
373_R	383_I	0.910	0.41
365_T	370_V	0.909	0.41
327_W	402_E	0.907	0.41
266_F	347_W	0.905	0.41
274_V	425_L	0.903	0.41
310_F	331_S	0.902	0.41
269_S	300_E	0.902	0.41
227_I	231_V	0.899	0.41
49_T	274_V	0.892	0.40
231_V	308_I	0.891	0.40
346_S	350_L	0.890	0.40
174_N	237_T	0.887	0.40
183_F	211_I	0.887	0.40
17_K	20_F	0.886	0.40
171_W	235_P	0.886	0.40
78_S	250_L	0.883	0.40
5_A	12_S	0.881	0.39
199_I	300_E	0.880	0.39
228_N	304_F	0.876	0.39
182_D	186_Y	0.871	0.39
116_D	119_Y	0.870	0.39
14_F	22_K	0.868	0.39
146_L	363_K	0.868	0.39
270_E	278_L	0.866	0.38
101_A	335_I	0.865	0.38
23_K	30_S	0.863	0.38
181_P	209_Y	0.862	0.38
129_K	133_K	0.859	0.38
307_D	363_K	0.858	0.38
208_Y	213_F	0.858	0.38
406_K	421_V	0.858	0.38
314_K	350_L	0.856	0.38
244_S	423_S	0.853	0.38
54_Y	106_T	0.850	0.37
153_T	157_E	0.849	0.37
195_L	292_V	0.849	0.37
217_F	328_N	0.847	0.37
303_A	311_W	0.846	0.37
300_E	405_F	0.845	0.37
132_T	394_E	0.843	0.37
398_K	402_E	0.843	0.37
320_L	408_L	0.842	0.37
295_L	367_A	0.841	0.37
351_I	359_I	0.840	0.37
106_T	109_G	0.840	0.37
378_G	381_P	0.839	0.37
372_I	383_I	0.836	0.36
229_E	232_T	0.835	0.36
299_F	366_K	0.834	0.36
338_Y	407_Y	0.831	0.36
296_H	321_S	0.830	0.36
139_K	142_K	0.824	0.36
9_Y	192_P	0.823	0.36
285_L	289_T	0.823	0.36
274_V	376_P	0.823	0.36
87_I	234_L	0.821	0.36
176_T	341_D	0.821	0.36
45_W	49_T	0.821	0.36
285_L	293_S	0.820	0.35
145_N	182_D	0.820	0.35
277_I	280_E	0.819	0.35
231_V	336_F	0.819	0.35
125_V	220_L	0.818	0.35
9_Y	24_P	0.818	0.35
401_D	414_P	0.818	0.35
9_Y	255_D	0.817	0.35
21_G	26_P	0.814	0.35
232_T	425_L	0.808	0.35
315_K	425_L	0.805	0.35
154_E	227_I	0.805	0.35
417_I	420_A	0.801	0.34
383_I	386_E	0.801	0.34
106_T	111_S	0.801	0.34
209_Y	285_L	0.799	0.34
234_L	404_A	0.797	0.34
131_L	275_K	0.796	0.34
356_G	360_E	0.795	0.34
283_P	352_S	0.790	0.34
170_H	276_R	0.788	0.33
394_E	400_Y	0.787	0.33
406_K	409_S	0.787	0.33
201_L	327_W	0.786	0.33
218_W	279_L	0.786	0.33
194_P	249_Q	0.785	0.33
43_P	312_R	0.785	0.33
2_I	32_P	0.784	0.33
176_T	284_Y	0.783	0.33
281_T	299_F	0.782	0.33
295_L	298_V	0.781	0.33
152_E	162_E	0.781	0.33
273_E	408_L	0.780	0.33
53_L	212_L	0.779	0.33
23_K	37_S	0.779	0.33
213_F	216_D	0.778	0.33
292_V	306_N	0.775	0.33
235_P	424_L	0.774	0.33
15_F	20_F	0.773	0.33
9_Y	16_M	0.770	0.32
28_P	160_E	0.770	0.32
90_P	99_L	0.769	0.32
19_F	22_K	0.769	0.32
108_S	225_I	0.767	0.32
323_R	397_T	0.766	0.32
275_K	345_T	0.765	0.32
273_E	410_Y	0.764	0.32
392_E	396_K	0.764	0.32
99_L	161_E	0.763	0.32
65_L	104_F	0.761	0.32
127_F	200_R	0.760	0.32
146_L	424_L	0.760	0.32
217_F	267_S	0.757	0.32
52_D	70_K	0.754	0.31
168_V	226_P	0.753	0.31
215_N	315_K	0.751	0.31
24_P	28_P	0.749	0.31
416_L	419_Y	0.747	0.31
140_V	151_E	0.744	0.31
315_K	372_I	0.744	0.31
305_K	321_S	0.744	0.31
195_L	199_I	0.736	0.30
51_L	72_F	0.734	0.30
33_S	39_L	0.733	0.30
228_N	231_V	0.733	0.30
289_T	292_V	0.732	0.30
23_K	31_D	0.731	0.30
309_S	313_K	0.729	0.30
414_P	419_Y	0.726	0.30
161_E	229_E	0.726	0.30
295_L	418_G	0.725	0.30
414_P	418_G	0.722	0.29
112_P	370_V	0.722	0.29
9_Y	21_G	0.721	0.29
308_I	408_L	0.721	0.29
233_E	333_L	0.720	0.29
17_K	28_P	0.720	0.29
146_L	303_A	0.718	0.29
22_K	26_P	0.718	0.29
4_R	19_F	0.717	0.29
270_E	387_D	0.716	0.29
218_W	338_Y	0.715	0.29
3_L	7_V	0.714	0.29
246_W	335_I	0.714	0.29
18_Y	39_L	0.712	0.29
103_V	242_P	0.712	0.29
10_F	18_Y	0.711	0.29
41_A	179_L	0.709	0.29
364_I	424_L	0.708	0.29
311_W	324_S	0.708	0.29
161_E	165_D	0.707	0.29
178_N	241_S	0.707	0.29
234_L	313_K	0.706	0.29
177_L	403_L	0.704	0.28
247_K	281_T	0.704	0.28
186_Y	192_P	0.703	0.28
200_R	411_V	0.703	0.28
221_R	346_S	0.701	0.28
108_S	124_A	0.700	0.28
285_L	367_A	0.697	0.28
299_F	310_F	0.697	0.28
405_F	419_Y	0.696	0.28
270_E	281_T	0.696	0.28
324_S	415_L	0.695	0.28
195_L	198_Y	0.695	0.28
167_I	369_D	0.694	0.28
170_H	408_L	0.693	0.28
11_I	15_F	0.692	0.28
172_H	300_E	0.692	0.28
392_E	398_K	0.691	0.28
314_K	332_Q	0.690	0.28
208_Y	345_T	0.689	0.28
292_V	342_N	0.686	0.27
314_K	322_V	0.686	0.27
17_K	21_G	0.685	0.27
76_D	107_K	0.680	0.27
16_M	21_G	0.679	0.27
275_K	407_Y	0.679	0.27
106_T	124_A	0.679	0.27
172_H	416_L	0.679	0.27
102_H	285_L	0.676	0.27
259_K	415_L	0.675	0.27
350_L	425_L	0.675	0.27
95_N	250_L	0.669	0.27
269_S	276_R	0.669	0.27
324_S	406_K	0.669	0.27
247_K	349_I	0.669	0.27
91_E	98_T	0.667	0.26
392_E	400_Y	0.666	0.26
111_S	168_V	0.664	0.26
284_Y	288_L	0.663	0.26
310_F	389_H	0.663	0.26
394_E	405_F	0.662	0.26
24_P	378_G	0.658	0.26
24_P	33_S	0.657	0.26
305_K	415_L	0.657	0.26
164_K	227_I	0.655	0.26
35_Y	40_P	0.654	0.26
347_W	351_I	0.652	0.26
56_Y	137_K	0.652	0.26
4_R	7_V	0.652	0.26
180_V	349_I	0.652	0.26
24_P	41_A	0.651	0.26
335_I	346_S	0.650	0.26
55_V	149_G	0.650	0.26
264_L	379_S	0.649	0.25
27_C	30_S	0.646	0.25
91_E	232_T	0.646	0.25
111_S	411_V	0.646	0.25
277_I	282_N	0.644	0.25
65_L	68_K	0.643	0.25
88_K	243_L	0.643	0.25
57_L	94_Q	0.642	0.25
34_C	38_Y	0.642	0.25
172_H	215_N	0.640	0.25
285_L	324_S	0.640	0.25
67_W	271_I	0.639	0.25
13_S	18_Y	0.638	0.25
305_K	420_A	0.637	0.25
400_Y	405_F	0.637	0.25
30_S	34_C	0.635	0.25
340_L	361_A	0.635	0.25
132_T	343_E	0.634	0.25
310_F	353_Q	0.634	0.25
283_P	287_G	0.634	0.25
52_D	108_S	0.631	0.25
326_L	358_L	0.630	0.24
387_D	400_Y	0.629	0.24
401_D	423_S	0.629	0.24
12_S	17_K	0.626	0.24
2_I	10_F	0.624	0.24
60_K	212_L	0.624	0.24
174_N	364_I	0.623	0.24
48_G	95_N	0.623	0.24
73_T	250_L	0.623	0.24
2_I	20_F	0.621	0.24
11_I	20_F	0.621	0.24
359_I	362_W	0.620	0.24
285_L	352_S	0.619	0.24
194_P	197_Q	0.619	0.24
243_L	356_G	0.618	0.24
12_S	18_Y	0.617	0.24
98_T	298_V	0.615	0.24
248_F	394_E	0.615	0.24
257_S	339_L	0.615	0.24
21_G	28_P	0.615	0.24
157_E	160_E	0.614	0.24
28_P	39_L	0.614	0.24
297_S	351_I	0.614	0.24
63_E	355_I	0.613	0.24
275_K	366_K	0.612	0.24
314_K	360_E	0.610	0.23
123_K	334_I	0.610	0.23
14_F	21_G	0.608	0.23
69_E	315_K	0.607	0.23
251_Y	332_Q	0.606	0.23
7_V	32_P	0.605	0.23
209_Y	312_R	0.605	0.23
310_F	398_K	0.604	0.23
4_R	8_I	0.604	0.23
17_K	41_A	0.604	0.23
328_N	419_Y	0.603	0.23
180_V	416_L	0.603	0.23
296_H	362_W	0.603	0.23
269_S	280_E	0.603	0.23
209_Y	240_Y	0.603	0.23
305_K	319_G	0.602	0.23
322_V	380_L	0.601	0.23
76_D	352_S	0.597	0.23
286_L	296_H	0.597	0.23
32_P	421_V	0.597	0.23
408_L	420_A	0.597	0.23
7_V	179_L	0.595	0.23
325_I	413_Y	0.594	0.23
365_T	369_D	0.592	0.23
192_P	224_L	0.591	0.23
23_K	421_V	0.589	0.22
300_E	331_S	0.589	0.22
2_I	38_Y	0.586	0.22
222_S	277_I	0.585	0.22
148_G	151_E	0.585	0.22
98_T	130_P	0.584	0.22
6_F	31_D	0.584	0.22
33_S	151_E	0.583	0.22
275_K	406_K	0.582	0.22
26_P	30_S	0.581	0.22
216_D	404_A	0.580	0.22
296_H	319_G	0.580	0.22
308_I	317_L	0.579	0.22
102_H	134_Y	0.579	0.22
18_Y	251_Y	0.578	0.22
58_S	68_K	0.578	0.22
136_P	170_H	0.578	0.22
130_P	173_P	0.578	0.22
45_W	325_I	0.578	0.22
325_I	350_L	0.577	0.22
182_D	244_S	0.574	0.22
45_W	310_F	0.574	0.22
48_G	51_L	0.574	0.22
303_A	325_I	0.573	0.22
295_L	324_S	0.572	0.22
41_A	152_E	0.567	0.21
265_G	272_D	0.566	0.21
126_H	240_Y	0.564	0.21
353_Q	406_K	0.564	0.21
90_P	222_S	0.562	0.21
213_F	255_D	0.562	0.21
361_A	365_T	0.561	0.21
195_L	234_L	0.560	0.21
4_R	12_S	0.559	0.21
39_L	358_L	0.557	0.21
409_S	412_L	0.557	0.21
51_L	168_V	0.556	0.21
333_L	344_N	0.555	0.21
56_Y	366_K	0.555	0.21
363_K	414_P	0.553	0.21
145_N	366_K	0.553	0.21
373_R	386_E	0.552	0.21
255_D	259_K	0.551	0.21
89_V	147_L	0.550	0.21
2_I	31_D	0.548	0.20
271_I	308_I	0.548	0.20
314_K	327_W	0.548	0.20
190_Q	402_E	0.548	0.20
102_H	147_L	0.547	0.20
16_M	25_P	0.547	0.20
218_W	400_Y	0.547	0.20
278_L	412_L	0.546	0.20
56_Y	311_W	0.546	0.20
345_T	350_L	0.543	0.20
141_R	250_L	0.543	0.20
27_C	33_S	0.542	0.20
153_T	425_L	0.542	0.20
257_S	346_S	0.541	0.20
179_L	243_L	0.539	0.20
226_P	311_W	0.539	0.20
209_Y	353_Q	0.539	0.20
310_F	405_F	0.538	0.20
195_L	253_S	0.538	0.20
28_P	31_D	0.537	0.20
173_P	404_A	0.537	0.20
108_S	385_F	0.536	0.20
381_P	421_V	0.534	0.20
93_V	328_N	0.534	0.20
156_E	164_K	0.533	0.20
154_E	180_V	0.532	0.20
217_F	275_K	0.531	0.20
145_N	343_E	0.530	0.20
90_P	104_F	0.530	0.20
22_K	25_P	0.528	0.20
394_E	416_L	0.528	0.20
174_N	249_Q	0.528	0.20
25_P	34_C	0.527	0.20
215_N	342_N	0.526	0.20
71_N	149_G	0.526	0.20
45_W	268_G	0.525	0.19
247_K	289_T	0.525	0.19
155_E	374_R	0.523	0.19
364_I	372_I	0.521	0.19
76_D	252_A	0.521	0.19
202_T	236_L	0.520	0.19
308_I	323_R	0.519	0.19
222_S	261_Q	0.519	0.19
165_D	212_L	0.518	0.19
373_R	381_P	0.517	0.19
86_T	89_V	0.517	0.19
332_Q	346_S	0.514	0.19
329_V	342_N	0.513	0.19
172_H	253_S	0.512	0.19
69_E	81_R	0.512	0.19
243_L	276_R	0.511	0.19
88_K	306_N	0.511	0.19
236_L	348_M	0.511	0.19
267_S	413_Y	0.510	0.19
120_D	139_K	0.510	0.19
208_Y	315_K	0.509	0.19
77_W	168_V	0.508	0.19
224_L	410_Y	0.506	0.19
336_F	408_L	0.505	0.19
138_K	315_K	0.505	0.19
242_P	323_R	0.503	0.19
200_R	334_I	0.503	0.19
408_L	412_L	0.502	0.18
220_L	279_L	0.502	0.18
202_T	207_W	0.502	0.18
98_T	107_K	0.502	0.18
329_V	405_F	0.502	0.18
261_Q	369_D	0.501	0.18
83_I	227_I	0.501	0.18
217_F	220_L	0.501	0.18
181_P	248_F	0.501	0.18
227_I	243_L	0.501	0.18
125_V	421_V	0.500	0.18
70_K	372_I	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qncA	2	0.1925	37.9	0.974	Contact Map
4rngA	2	0.1948	26.5	0.976	Contact Map
4x5mA	2	0.216	24.8	0.976	Contact Map
3mk7C	2	0.1784	8.6	0.981	Contact Map
2v0pA	2	0.1948	2.8	0.985	Contact Map
1nkzB	1	0.0962	2.2	0.986	Contact Map
1z96A	1	0.0869	1.8	0.986	Contact Map
3oakC	1	0.0728	1.8	0.986	Contact Map
4xrpC	1	0.2019	1.7	0.986	Contact Map
1q2fA	1	0.0751	1.5	0.987	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0113 seconds.