AsmA - PFAM28P - GREMLIN Contacts

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AsmA - AsmA family

PFAM:	PF05170	Sequences: MKKLLKILLIILGGLVLLLVALVALVALFDPNDYKPEIEQQVSEATGRELTIDGDLGLSLFPWLGLSLGDVSLGNPDGFKEPPFASLDRADVSVALLPLLSKEVEVDTIRLDGLDLNLERDADGRNNWDDLLKASDAAAPAAPAQAPAPTSPSSPWALDIGGIEISNGRVTYDDAQTGTQLTLSDLNLSTGALAGGSLPAAKLELSGKLDADPAGFRDYLNGLKLKGTLSGEPLQGSGKTGGALLLADLAAPFPLQADLKLGATRLALAGTLTDPLNLSALDLTLKLSGWQSIAGNLSLSADELDSLADLLPLLGVTLPATPDYATLGRLSLSLDLGGSALSLALSDLTLKLDDSTFTGRALVGLSDLHGDLTYVTGGARPALRFDLKSDQLDLDRYLPPIGAAAADSPAAEAAAGGASAAPADKVLPVEPFDLDLLRGMDADVTLTIGRLTASGLPLSDLSLHLKAKDGVLTLDPLSAGLYGGSLEGTITLDARGAPPRLALKLNLRGVQLGPLLPDLAGMDPLSGTGNGDADLTGSGNSVAALLGSLNGTLSLLLNDGAISGLNLAQILREAKAKLGKLFGDKKTDFSCLAASFTIKNGVATNDDL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	608 (594)
Sequences:	2733 (2132)
Seq/√Len:	87.5
META:	0.611

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
537_G	548_S	5.719	1.00
114_L	168_G	4.600	1.00
121_D	125_R	4.503	1.00
393_D	452_T	4.474	1.00
460_D	480_G	4.466	1.00
43_S	49_E	4.265	1.00
24_A	28_L	4.207	1.00
53_D	70_D	3.894	1.00
504_K	534_D	3.719	1.00
88_D	113_G	3.408	1.00
482_Y	518_D	3.326	1.00
42_V	50_L	3.145	1.00
555_L	594_A	3.144	1.00
471_V	495_R	3.119	1.00
126_N	129_D	3.109	1.00
112_D	166_S	3.069	1.00
435_D	438_R	3.060	1.00
95_A	98_P	3.024	1.00
50_L	73_L	2.982	1.00
70_D	88_D	2.965	1.00
80_K	83_P	2.930	1.00
10_I	14_G	2.896	1.00
428_P	432_F	2.759	1.00
365_L	368_L	2.653	1.00
385_F	444_V	2.612	1.00
297_L	301_A	2.597	1.00
467_A	472_L	2.567	1.00
435_D	439_G	2.555	1.00
42_V	46_T	2.522	1.00
56_L	68_L	2.480	1.00
42_V	73_L	2.457	1.00
118_L	128_W	2.440	1.00
433_D	437_L	2.373	1.00
9_L	13_G	2.371	1.00
511_Q	514_P	2.346	1.00
434_L	437_L	2.321	1.00
40_Q	44_E	2.307	1.00
572_R	588_D	2.299	1.00
115_D	169_R	2.281	1.00
25_L	29_F	2.271	1.00
568_A	588_D	2.236	1.00
32_N	55_D	2.231	1.00
112_D	167_N	2.223	1.00
46_T	73_L	2.189	1.00
310_L	314_L	2.176	1.00
596_F	603_A	2.160	1.00
41_Q	45_A	2.156	1.00
594_A	605_N	2.147	1.00
391_Q	450_R	2.146	1.00
52_I	71_V	2.143	1.00
393_D	396_R	2.142	1.00
488_G	505_L	2.136	1.00
595_S	605_N	2.094	1.00
363_V	368_L	2.084	1.00
86_S	115_D	2.072	1.00
48_R	130_D	2.068	1.00
120_R	172_Y	2.047	1.00
434_L	438_R	2.042	1.00
5_L	9_L	2.016	1.00
46_T	50_L	2.007	1.00
427_L	432_F	1.980	1.00
113_G	167_N	1.971	1.00
598_I	603_A	1.966	1.00
248_D	251_A	1.959	1.00
75_N	79_F	1.954	1.00
321_T	325_A	1.950	1.00
457_P	518_D	1.949	1.00
95_A	105_E	1.919	1.00
428_P	431_P	1.904	1.00
120_R	174_D	1.901	1.00
49_E	74_G	1.887	1.00
231_G	234_L	1.885	1.00
568_A	572_R	1.883	1.00
7_I	11_I	1.878	1.00
471_V	493_D	1.867	1.00
386_D	445_T	1.834	1.00
364_G	368_L	1.811	1.00
75_N	78_G	1.761	1.00
48_R	84_F	1.754	1.00
297_L	304_L	1.750	1.00
550_N	600_N	1.747	1.00
224_K	227_G	1.744	1.00
321_T	326_T	1.720	1.00
436_L	439_G	1.718	1.00
31_P	34_Y	1.710	1.00
537_G	545_L	1.708	1.00
301_A	304_L	1.701	1.00
297_L	302_D	1.700	1.00
433_D	436_L	1.697	1.00
389_S	448_I	1.682	1.00
318_L	321_T	1.677	1.00
244_L	248_D	1.670	1.00
41_Q	44_E	1.661	1.00
117_N	171_T	1.643	1.00
431_P	434_L	1.637	1.00
388_K	447_T	1.635	1.00
599_K	604_T	1.616	1.00
322_P	327_L	1.607	1.00
80_K	119_E	1.603	1.00
295_G	301_A	1.603	1.00
553_L	596_F	1.591	1.00
183_L	191_G	1.589	1.00
429_V	434_L	1.588	1.00
386_D	447_T	1.587	1.00
471_V	491_T	1.586	1.00
437_L	444_V	1.581	1.00
429_V	432_F	1.576	1.00
426_V	430_E	1.569	1.00
87_L	90_A	1.567	1.00
476_P	490_I	1.564	1.00
248_D	252_P	1.561	1.00
69_G	89_R	1.556	1.00
390_D	449_G	1.552	1.00
389_S	397_Y	1.545	1.00
363_V	366_S	1.544	1.00
256_Q	259_L	1.540	1.00
321_T	324_Y	1.540	1.00
184_S	191_G	1.537	1.00
433_D	438_R	1.535	1.00
514_P	518_D	1.524	1.00
319_P	322_P	1.518	1.00
323_D	396_R	1.515	1.00
566_N	588_D	1.512	1.00
191_G	196_G	1.508	1.00
119_E	175_A	1.506	1.00
425_K	431_P	1.504	1.00
428_P	433_D	1.502	1.00
314_L	319_P	1.499	1.00
550_N	599_K	1.492	1.00
449_G	460_D	1.489	1.00
249_L	252_P	1.484	0.99
390_D	397_Y	1.471	0.99
563_S	586_K	1.469	0.99
73_L	84_F	1.462	0.99
111_L	114_L	1.455	0.99
281_L	285_L	1.454	0.99
447_T	462_S	1.448	0.99
456_L	519_L	1.435	0.99
515_L	518_D	1.425	0.99
213_P	216_F	1.424	0.99
507_L	510_V	1.419	0.99
480_G	485_S	1.401	0.99
432_F	437_L	1.398	0.99
244_L	247_A	1.397	0.99
6_K	10_I	1.358	0.99
21_A	25_L	1.358	0.99
60_L	65_G	1.357	0.99
48_R	75_N	1.356	0.99
448_I	451_L	1.350	0.99
75_N	84_F	1.350	0.99
443_D	466_K	1.346	0.99
209_L	216_F	1.343	0.99
445_T	464_H	1.340	0.99
293_I	297_L	1.339	0.99
75_N	119_E	1.337	0.99
223_L	227_G	1.336	0.99
375_V	378_G	1.330	0.99
32_N	38_I	1.330	0.99
188_L	196_G	1.330	0.99
426_V	431_P	1.327	0.99
75_N	128_W	1.326	0.99
486_L	505_L	1.324	0.99
315_G	319_P	1.322	0.99
325_A	328_G	1.322	0.99
231_G	235_Q	1.321	0.99
84_F	130_D	1.314	0.99
364_G	367_D	1.311	0.99
500_R	538_S	1.306	0.99
56_L	66_L	1.301	0.99
489_T	504_K	1.300	0.99
29_F	34_Y	1.298	0.99
439_G	443_D	1.295	0.99
479_A	486_L	1.291	0.99
65_G	91_D	1.291	0.99
503_L	535_L	1.289	0.99
43_S	50_L	1.283	0.99
491_T	502_A	1.283	0.99
321_T	327_L	1.275	0.98
184_S	190_T	1.272	0.98
425_K	430_E	1.270	0.98
438_R	442_A	1.270	0.98
304_L	307_L	1.270	0.98
34_Y	38_I	1.269	0.98
35_K	54_G	1.269	0.98
432_F	435_D	1.264	0.98
32_N	36_P	1.263	0.98
48_R	74_G	1.261	0.98
53_D	69_G	1.260	0.98
380_R	441_D	1.260	0.98
212_D	218_D	1.258	0.98
572_R	576_A	1.253	0.98
212_D	216_F	1.252	0.98
354_D	396_R	1.250	0.98
285_L	289_G	1.246	0.98
511_Q	528_T	1.244	0.98
529_G	533_A	1.239	0.98
462_S	478_S	1.236	0.98
218_D	222_G	1.234	0.98
502_A	536_T	1.232	0.98
7_I	10_I	1.232	0.98
113_G	168_G	1.228	0.98
238_G	241_G	1.227	0.98
110_R	164_E	1.225	0.98
478_S	487_E	1.223	0.98
566_N	569_Q	1.223	0.98
438_R	441_D	1.218	0.98
213_P	218_D	1.217	0.98
98_P	104_V	1.217	0.98
200_A	203_L	1.214	0.98
57_G	67_S	1.213	0.98
506_N	532_D	1.212	0.98
513_G	523_D	1.212	0.98
108_T	162_G	1.208	0.98
122_A	178_G	1.207	0.98
456_L	482_Y	1.198	0.98
246_L	249_L	1.197	0.98
351_K	356_T	1.194	0.98
535_L	598_I	1.193	0.98
437_L	440_M	1.192	0.98
122_A	175_A	1.189	0.98
517_P	523_D	1.189	0.98
353_D	359_G	1.172	0.97
426_V	429_V	1.167	0.97
198_L	201_A	1.158	0.97
183_L	186_L	1.156	0.97
308_A	313_L	1.154	0.97
188_L	191_G	1.154	0.97
532_D	554_S	1.150	0.97
501_L	545_L	1.149	0.97
493_D	500_R	1.147	0.97
429_V	433_D	1.142	0.97
30_D	33_D	1.136	0.97
475_D	489_T	1.134	0.97
253_F	256_Q	1.133	0.97
224_K	231_G	1.126	0.97
311_L	314_L	1.125	0.97
245_L	249_L	1.124	0.97
479_A	482_Y	1.122	0.96
569_Q	573_E	1.119	0.96
31_P	56_L	1.118	0.96
212_D	215_G	1.117	0.96
307_L	311_L	1.116	0.96
441_D	444_V	1.116	0.96
59_S	63_W	1.114	0.96
89_R	112_D	1.110	0.96
173_D	180_Q	1.107	0.96
6_K	9_L	1.105	0.96
36_P	40_Q	1.102	0.96
307_L	310_L	1.090	0.96
23_V	26_V	1.089	0.96
326_T	330_L	1.086	0.96
385_F	465_L	1.084	0.96
260_K	265_R	1.082	0.96
299_L	302_D	1.082	0.96
440_M	444_V	1.081	0.96
437_L	441_D	1.080	0.96
485_S	508_R	1.078	0.96
183_L	190_T	1.070	0.95
543_A	547_G	1.069	0.95
231_G	236_G	1.067	0.95
526_S	561_A	1.066	0.95
281_L	289_G	1.066	0.95
388_K	449_G	1.064	0.95
5_L	17_L	1.058	0.95
482_Y	515_L	1.057	0.95
34_Y	37_E	1.055	0.95
429_V	435_D	1.053	0.95
591_C	605_N	1.052	0.95
219_Y	222_G	1.052	0.95
72_S	83_P	1.050	0.95
315_G	321_T	1.045	0.95
14_G	18_L	1.040	0.95
252_P	259_L	1.036	0.95
32_N	35_K	1.035	0.95
494_A	499_P	1.034	0.94
108_T	164_E	1.034	0.94
3_K	10_I	1.030	0.94
63_W	95_A	1.025	0.94
183_L	188_L	1.018	0.94
561_A	586_K	1.018	0.94
221_N	227_G	1.017	0.94
424_D	428_P	1.010	0.94
198_L	203_L	1.009	0.94
435_D	440_M	1.008	0.94
245_L	248_D	1.006	0.94
35_K	39_E	1.006	0.94
557_L	566_N	1.006	0.94
596_F	605_N	1.004	0.94
512_L	557_L	1.004	0.94
439_G	444_V	1.002	0.93
452_T	457_P	0.996	0.93
363_V	367_D	0.994	0.93
88_D	112_D	0.992	0.93
53_D	72_S	0.991	0.93
307_L	319_P	0.990	0.93
566_N	572_R	0.988	0.93
523_D	563_S	0.986	0.93
438_R	470_G	0.985	0.93
225_L	229_L	0.984	0.93
37_E	40_Q	0.982	0.93
232_E	236_G	0.982	0.93
308_A	314_L	0.981	0.93
207_G	565_L	0.979	0.93
322_P	325_A	0.973	0.92
190_T	193_L	0.973	0.92
218_D	221_N	0.972	0.92
473_T	491_T	0.971	0.92
209_L	214_A	0.968	0.92
31_P	58_L	0.965	0.92
309_D	313_L	0.964	0.92
319_P	327_L	0.963	0.92
191_G	195_G	0.961	0.92
67_S	91_D	0.958	0.92
259_L	265_R	0.958	0.92
310_L	313_L	0.955	0.92
124_G	127_N	0.955	0.92
324_Y	327_L	0.954	0.92
427_L	431_P	0.952	0.92
433_D	440_M	0.952	0.92
430_E	434_L	0.947	0.91
466_K	475_D	0.945	0.91
520_A	523_D	0.944	0.91
184_S	196_G	0.944	0.91
54_G	68_L	0.943	0.91
427_L	430_E	0.942	0.91
355_S	359_G	0.941	0.91
338_G	341_L	0.940	0.91
87_L	111_L	0.940	0.91
483_G	511_Q	0.940	0.91
84_F	113_G	0.939	0.91
248_D	259_L	0.937	0.91
323_D	326_T	0.934	0.91
193_L	196_G	0.932	0.91
297_L	305_D	0.931	0.91
8_L	12_L	0.930	0.91
556_L	593_A	0.929	0.91
227_G	231_G	0.928	0.91
265_R	271_T	0.927	0.91
458_L	461_L	0.927	0.91
335_D	347_D	0.924	0.90
255_L	260_K	0.919	0.90
435_D	442_A	0.919	0.90
26_V	29_F	0.917	0.90
59_S	65_G	0.913	0.90
13_G	17_L	0.913	0.90
321_T	328_G	0.912	0.90
25_L	28_L	0.910	0.90
566_N	586_K	0.907	0.90
171_T	180_Q	0.903	0.89
283_L	287_L	0.903	0.89
227_G	234_L	0.902	0.89
183_L	193_L	0.901	0.89
63_W	93_S	0.900	0.89
202_K	205_L	0.899	0.89
425_K	429_V	0.899	0.89
431_P	435_D	0.896	0.89
24_A	27_A	0.893	0.89
225_L	228_T	0.891	0.89
427_L	434_L	0.891	0.89
316_V	319_P	0.890	0.89
291_Q	294_A	0.889	0.89
229_L	232_E	0.888	0.89
313_L	322_P	0.888	0.89
245_L	257_A	0.887	0.89
435_D	441_D	0.886	0.88
281_L	284_T	0.886	0.88
291_Q	295_G	0.880	0.88
433_D	439_G	0.880	0.88
39_E	43_S	0.879	0.88
260_K	264_T	0.878	0.88
222_G	227_G	0.878	0.88
240_T	243_A	0.878	0.88
221_N	224_K	0.877	0.88
589_F	592_L	0.876	0.88
225_L	235_Q	0.875	0.88
214_A	227_G	0.874	0.88
311_L	316_V	0.872	0.88
536_T	550_N	0.870	0.88
544_A	548_S	0.869	0.87
305_D	309_D	0.868	0.87
255_L	258_D	0.868	0.87
428_P	434_L	0.867	0.87
318_L	327_L	0.865	0.87
295_G	299_L	0.865	0.87
76_P	119_E	0.864	0.87
336_L	341_L	0.862	0.87
200_A	206_S	0.862	0.87
32_N	56_L	0.861	0.87
27_A	31_P	0.860	0.87
319_P	325_A	0.859	0.87
32_N	54_G	0.858	0.87
492_L	501_L	0.857	0.87
355_S	389_S	0.856	0.87
53_D	88_D	0.854	0.87
339_S	342_S	0.853	0.86
306_S	314_L	0.853	0.86
395_D	398_L	0.852	0.86
298_S	301_A	0.849	0.86
184_S	188_L	0.849	0.86
575_K	588_D	0.847	0.86
412_E	415_A	0.846	0.86
73_L	76_P	0.845	0.86
418_A	422_P	0.842	0.86
10_I	13_G	0.842	0.86
572_R	590_S	0.841	0.86
437_L	442_A	0.840	0.86
30_D	56_L	0.838	0.86
505_L	533_A	0.837	0.85
263_A	266_L	0.837	0.85
426_V	432_F	0.836	0.85
25_L	34_Y	0.834	0.85
24_A	29_F	0.832	0.85
75_N	130_D	0.832	0.85
116_L	160_I	0.831	0.85
259_L	268_L	0.831	0.85
566_N	587_T	0.831	0.85
384_R	443_D	0.831	0.85
231_G	237_S	0.829	0.85
234_L	238_G	0.828	0.85
121_D	124_G	0.827	0.85
542_V	546_L	0.823	0.84
323_D	327_L	0.823	0.84
190_T	196_G	0.823	0.84
278_L	281_L	0.823	0.84
48_R	73_L	0.821	0.84
394_L	398_L	0.820	0.84
37_E	41_Q	0.817	0.84
540_N	544_A	0.811	0.84
304_L	310_L	0.803	0.83
393_D	397_Y	0.802	0.83
79_F	119_E	0.801	0.83
225_L	231_G	0.800	0.83
211_A	216_F	0.798	0.83
573_E	577_K	0.798	0.83
568_A	590_S	0.797	0.83
145_Q	148_A	0.793	0.82
261_L	265_R	0.792	0.82
207_G	211_A	0.790	0.82
47_G	75_N	0.788	0.82
227_G	233_P	0.787	0.82
395_D	455_G	0.787	0.82
322_P	326_T	0.785	0.82
43_S	46_T	0.784	0.82
183_L	197_S	0.782	0.81
220_L	231_G	0.780	0.81
203_L	219_Y	0.778	0.81
302_D	307_L	0.777	0.81
314_L	317_T	0.775	0.81
184_S	187_N	0.775	0.81
572_R	575_K	0.774	0.81
311_L	315_G	0.773	0.81
211_A	215_G	0.772	0.81
79_F	82_P	0.769	0.80
541_S	544_A	0.769	0.80
222_G	235_Q	0.769	0.80
126_N	130_D	0.768	0.80
6_K	11_I	0.767	0.80
184_S	195_G	0.764	0.80
74_G	84_F	0.764	0.80
597_T	604_T	0.763	0.80
264_T	268_L	0.763	0.80
483_G	514_P	0.762	0.80
320_A	327_L	0.761	0.80
253_F	257_A	0.760	0.79
81_E	119_E	0.760	0.79
174_D	177_T	0.760	0.79
278_L	283_L	0.760	0.79
424_D	430_E	0.759	0.79
306_S	312_P	0.757	0.79
303_E	306_S	0.756	0.79
421_A	425_K	0.755	0.79
200_A	204_E	0.753	0.79
68_L	71_V	0.752	0.79
97_L	100_L	0.750	0.79
399_P	461_L	0.750	0.79
183_L	195_G	0.749	0.78
261_L	270_G	0.748	0.78
203_L	213_P	0.746	0.78
121_D	175_A	0.746	0.78
293_I	301_A	0.742	0.78
341_L	367_D	0.742	0.78
52_I	72_S	0.741	0.78
103_E	157_A	0.740	0.78
413_A	419_S	0.739	0.78
445_T	462_S	0.738	0.77
183_L	187_N	0.738	0.77
215_G	236_G	0.737	0.77
296_N	299_L	0.735	0.77
85_A	116_L	0.735	0.77
56_L	104_V	0.735	0.77
509_G	528_T	0.733	0.77
299_L	304_L	0.732	0.77
39_E	51_T	0.732	0.77
232_E	237_S	0.732	0.77
75_N	126_N	0.731	0.77
312_P	315_G	0.729	0.77
128_W	172_Y	0.729	0.77
226_K	232_E	0.729	0.77
569_Q	585_K	0.729	0.77
313_L	446_L	0.728	0.76
225_L	236_G	0.728	0.76
475_D	486_L	0.727	0.76
48_R	58_L	0.727	0.76
319_P	324_Y	0.725	0.76
450_R	459_S	0.724	0.76
28_L	42_V	0.723	0.76
409_P	412_E	0.722	0.76
282_D	289_G	0.721	0.76
560_G	589_F	0.721	0.76
83_P	86_S	0.719	0.76
360_R	364_G	0.719	0.76
50_L	54_G	0.717	0.75
23_V	27_A	0.717	0.75
26_V	31_P	0.716	0.75
297_L	307_L	0.715	0.75
5_L	14_G	0.715	0.75
321_T	334_L	0.714	0.75
574_A	577_K	0.712	0.75
339_S	343_L	0.712	0.75
279_S	282_D	0.711	0.75
360_R	363_V	0.710	0.75
502_A	534_D	0.709	0.75
98_P	105_E	0.709	0.75
3_K	7_I	0.708	0.74
310_L	316_V	0.708	0.74
280_A	283_L	0.708	0.74
564_G	568_A	0.708	0.74
319_P	326_T	0.707	0.74
31_P	36_P	0.707	0.74
288_S	292_S	0.707	0.74
228_T	234_L	0.705	0.74
389_S	396_R	0.705	0.74
571_L	574_A	0.704	0.74
306_S	310_L	0.704	0.74
201_A	212_D	0.704	0.74
306_S	309_D	0.702	0.74
575_K	590_S	0.702	0.74
10_I	17_L	0.702	0.74
482_Y	514_P	0.701	0.74
239_K	242_G	0.699	0.74
305_D	308_A	0.699	0.74
496_G	500_R	0.698	0.73
407_D	412_E	0.695	0.73
410_A	413_A	0.694	0.73
295_G	302_D	0.693	0.73
385_F	390_D	0.693	0.73
262_G	270_G	0.693	0.73
279_S	289_G	0.693	0.73
395_D	453_A	0.691	0.73
211_A	214_A	0.690	0.73
64_L	191_G	0.690	0.73
12_L	16_V	0.688	0.72
209_L	212_D	0.688	0.72
488_G	504_K	0.688	0.72
477_L	488_G	0.687	0.72
335_D	338_G	0.686	0.72
214_A	228_T	0.686	0.72
61_F	65_G	0.686	0.72
218_D	224_K	0.685	0.72
58_L	62_P	0.685	0.72
260_K	263_A	0.684	0.72
200_A	213_P	0.683	0.72
247_A	252_P	0.683	0.72
553_L	603_A	0.682	0.72
257_A	260_K	0.681	0.72
215_G	218_D	0.680	0.71
208_K	214_A	0.680	0.71
201_A	205_L	0.679	0.71
165_I	168_G	0.679	0.71
50_L	74_G	0.677	0.71
372_L	375_V	0.677	0.71
59_S	62_P	0.676	0.71
233_P	239_K	0.675	0.71
79_F	121_D	0.674	0.71
5_L	10_I	0.674	0.71
550_N	602_V	0.673	0.71
244_L	249_L	0.672	0.71
184_S	193_L	0.670	0.70
39_E	42_V	0.670	0.70
72_S	161_G	0.669	0.70
92_V	104_V	0.667	0.70
513_G	526_S	0.666	0.70
267_A	279_S	0.666	0.70
427_L	440_M	0.665	0.70
305_D	313_L	0.665	0.70
25_L	31_P	0.664	0.70
84_F	117_N	0.664	0.70
244_L	256_Q	0.664	0.70
18_L	21_A	0.663	0.70
204_E	207_G	0.662	0.69
11_I	14_G	0.662	0.69
227_G	243_A	0.662	0.69
130_D	589_F	0.662	0.69
87_L	112_D	0.662	0.69
260_K	271_T	0.661	0.69
539_G	544_A	0.660	0.69
374_Y	378_G	0.660	0.69
188_L	195_G	0.659	0.69
190_T	197_S	0.659	0.69
209_L	223_L	0.659	0.69
595_S	606_D	0.656	0.69
578_L	581_L	0.656	0.69
202_K	207_G	0.655	0.69
117_N	173_D	0.655	0.69
225_L	230_S	0.655	0.69
423_A	428_P	0.654	0.69
225_L	232_E	0.653	0.68
353_D	397_Y	0.653	0.68
198_L	212_D	0.652	0.68
34_Y	55_D	0.652	0.68
302_D	305_D	0.652	0.68
486_L	490_I	0.652	0.68
313_L	316_V	0.651	0.68
266_L	272_L	0.651	0.68
411_A	414_A	0.647	0.68
200_A	214_A	0.647	0.68
278_L	285_L	0.646	0.68
88_D	114_L	0.646	0.68
76_P	130_D	0.645	0.67
464_H	475_D	0.644	0.67
162_G	172_Y	0.643	0.67
91_D	112_D	0.643	0.67
571_L	575_K	0.643	0.67
34_Y	58_L	0.642	0.67
579_G	583_G	0.640	0.67
237_S	240_T	0.639	0.67
34_Y	56_L	0.639	0.67
517_P	521_G	0.638	0.67
255_L	259_L	0.637	0.67
425_K	432_F	0.637	0.67
193_L	197_S	0.636	0.66
290_W	293_I	0.636	0.66
61_F	64_L	0.635	0.66
430_E	433_D	0.635	0.66
327_L	330_L	0.634	0.66
225_L	234_L	0.634	0.66
264_T	271_T	0.634	0.66
47_G	76_P	0.634	0.66
306_S	322_P	0.633	0.66
413_A	418_A	0.632	0.66
256_Q	260_K	0.632	0.66
465_L	472_L	0.632	0.66
543_A	546_L	0.632	0.66
205_L	212_D	0.631	0.66
569_Q	572_R	0.631	0.66
561_A	588_D	0.631	0.66
264_T	270_G	0.630	0.66
229_L	238_G	0.630	0.66
229_L	236_G	0.628	0.65
222_G	225_L	0.627	0.65
252_P	256_Q	0.627	0.65
233_P	236_G	0.627	0.65
191_G	197_S	0.627	0.65
413_A	416_G	0.624	0.65
389_S	392_L	0.624	0.65
120_R	176_Q	0.623	0.65
565_L	568_A	0.623	0.65
323_D	328_G	0.621	0.65
258_D	268_L	0.619	0.64
53_D	71_V	0.619	0.64
220_L	227_G	0.619	0.64
354_D	359_G	0.619	0.64
258_D	262_G	0.616	0.64
448_I	482_Y	0.615	0.64
257_A	268_L	0.614	0.64
112_D	164_E	0.611	0.63
43_S	51_T	0.611	0.63
557_L	589_F	0.610	0.63
228_T	231_G	0.610	0.63
411_A	416_G	0.610	0.63
198_L	205_L	0.610	0.63
315_G	322_P	0.610	0.63
526_S	586_K	0.609	0.63
316_V	321_T	0.609	0.63
156_W	160_I	0.609	0.63
550_N	553_L	0.607	0.63
553_L	598_I	0.606	0.63
120_R	129_D	0.606	0.63
89_R	110_R	0.606	0.63
72_S	86_S	0.605	0.63
586_K	590_S	0.605	0.63
294_A	297_L	0.605	0.63
414_A	422_P	0.604	0.62
227_G	238_G	0.603	0.62
473_T	489_T	0.602	0.62
599_K	606_D	0.602	0.62
561_A	572_R	0.601	0.62
87_L	114_L	0.601	0.62
307_L	314_L	0.600	0.62
526_S	563_S	0.599	0.62
568_A	575_K	0.599	0.62
36_P	39_E	0.598	0.62
218_D	231_G	0.598	0.62
229_L	242_G	0.598	0.62
2_K	6_K	0.596	0.61
570_I	573_E	0.596	0.61
566_N	579_G	0.596	0.61
124_G	176_Q	0.595	0.61
28_L	34_Y	0.594	0.61
214_A	217_R	0.593	0.61
312_P	319_P	0.592	0.61
42_V	48_R	0.592	0.61
227_G	241_G	0.592	0.61
4_L	14_G	0.591	0.61
4_L	7_I	0.591	0.61
254_P	264_T	0.590	0.61
318_L	330_L	0.589	0.60
93_S	107_D	0.589	0.60
48_R	476_P	0.588	0.60
120_R	126_N	0.588	0.60
248_D	255_L	0.588	0.60
38_I	55_D	0.587	0.60
26_V	60_L	0.586	0.60
259_L	262_G	0.586	0.60
91_D	110_R	0.585	0.60
307_L	315_G	0.585	0.60
293_I	299_L	0.584	0.60
550_N	598_I	0.583	0.60
245_L	254_P	0.582	0.60
265_R	269_A	0.582	0.60
419_S	422_P	0.581	0.59
597_T	606_D	0.581	0.59
191_G	194_A	0.578	0.59
510_V	529_G	0.577	0.59
126_N	172_Y	0.577	0.59
84_F	120_R	0.576	0.59
76_P	79_F	0.576	0.59
223_L	237_S	0.576	0.59
474_L	477_L	0.576	0.59
325_A	341_L	0.575	0.59
183_L	196_G	0.575	0.59
424_D	429_V	0.575	0.59
448_I	461_L	0.574	0.59
552_T	597_T	0.574	0.59
249_L	257_A	0.574	0.59
38_I	56_L	0.571	0.58
253_F	259_L	0.571	0.58
435_D	444_V	0.571	0.58
63_W	97_L	0.567	0.58
495_R	499_P	0.567	0.58
280_A	289_G	0.567	0.58
359_G	363_V	0.566	0.57
298_S	302_D	0.566	0.57
412_E	417_G	0.565	0.57
20_V	23_V	0.565	0.57
297_L	300_S	0.564	0.57
74_G	172_Y	0.564	0.57
93_S	108_T	0.563	0.57
226_K	242_G	0.563	0.57
381_P	384_R	0.562	0.57
397_Y	400_P	0.562	0.57
561_A	589_F	0.562	0.57
81_E	115_D	0.562	0.57
269_A	492_L	0.562	0.57
113_G	159_D	0.562	0.57
228_T	232_E	0.561	0.57
359_G	364_G	0.561	0.57
587_T	595_S	0.561	0.57
6_K	19_L	0.560	0.57
280_A	285_L	0.560	0.57
118_L	126_N	0.560	0.57
15_L	20_V	0.559	0.57
562_I	568_A	0.558	0.56
216_F	222_G	0.557	0.56
302_D	308_A	0.556	0.56
29_F	159_D	0.556	0.56
212_D	223_L	0.556	0.56
294_A	301_A	0.556	0.56
204_E	209_L	0.555	0.56
326_T	329_R	0.555	0.56
428_P	437_L	0.554	0.56
569_Q	577_K	0.553	0.56
582_F	585_K	0.552	0.56
431_P	438_R	0.552	0.56
270_G	294_A	0.551	0.55
432_F	438_R	0.551	0.55
319_P	323_D	0.551	0.55
418_A	428_P	0.550	0.55
230_S	235_Q	0.550	0.55
210_D	215_G	0.550	0.55
420_A	423_A	0.550	0.55
424_D	432_F	0.550	0.55
357_F	367_D	0.549	0.55
492_L	500_R	0.549	0.55
203_L	209_L	0.549	0.55
230_S	237_S	0.548	0.55
25_L	84_F	0.548	0.55
394_L	400_P	0.548	0.55
257_A	265_R	0.548	0.55
198_L	202_K	0.546	0.55
293_I	302_D	0.546	0.55
218_D	236_G	0.546	0.55
262_G	277_N	0.546	0.55
30_D	54_G	0.545	0.55
544_A	549_L	0.544	0.55
207_G	214_A	0.544	0.55
61_F	67_S	0.542	0.54
71_V	87_L	0.541	0.54
397_Y	467_A	0.540	0.54
225_L	238_G	0.540	0.54
345_L	348_L	0.539	0.54
487_E	506_N	0.539	0.54
355_S	358_T	0.539	0.54
205_L	215_G	0.538	0.54
113_G	116_L	0.538	0.54
214_A	218_D	0.538	0.54
185_D	190_T	0.537	0.54
520_A	524_P	0.537	0.54
360_R	366_S	0.537	0.54
492_L	515_L	0.536	0.53
430_E	437_L	0.536	0.53
223_L	231_G	0.536	0.53
316_V	329_R	0.535	0.53
63_W	107_D	0.535	0.53
52_I	68_L	0.535	0.53
21_A	24_A	0.535	0.53
30_D	60_L	0.534	0.53
199_P	205_L	0.532	0.53
327_L	341_L	0.530	0.53
409_P	415_A	0.530	0.53
111_L	157_A	0.530	0.53
422_P	425_K	0.530	0.53
283_L	315_G	0.530	0.53
166_S	600_N	0.528	0.52
534_D	552_T	0.528	0.52
185_D	189_S	0.528	0.52
321_T	330_L	0.527	0.52
105_E	159_D	0.527	0.52
166_S	187_N	0.527	0.52
206_S	212_D	0.526	0.52
10_I	19_L	0.526	0.52
505_L	534_D	0.526	0.52
218_D	223_L	0.526	0.52
42_V	47_G	0.525	0.52
222_G	231_G	0.525	0.52
466_K	473_T	0.525	0.52
315_G	326_T	0.525	0.52
324_Y	348_L	0.525	0.52
20_V	24_A	0.524	0.52
88_D	166_S	0.524	0.52
336_L	348_L	0.524	0.52
114_L	165_I	0.524	0.52
549_L	601_G	0.524	0.52
78_G	119_E	0.524	0.52
79_F	83_P	0.523	0.52
200_A	205_L	0.520	0.51
245_L	250_A	0.520	0.51
293_I	296_N	0.520	0.51
32_N	52_I	0.519	0.51
283_L	291_Q	0.519	0.51
247_A	253_F	0.518	0.51
21_A	28_L	0.517	0.51
222_G	236_G	0.517	0.51
259_L	263_A	0.517	0.51
10_I	18_L	0.517	0.51
587_T	598_I	0.516	0.51
262_G	265_R	0.516	0.51
554_S	595_S	0.516	0.51
494_A	501_L	0.515	0.51
225_L	233_P	0.515	0.51
146_A	151_S	0.514	0.50
245_L	252_P	0.514	0.50
414_A	418_A	0.512	0.50
278_L	287_L	0.511	0.50
292_S	301_A	0.511	0.50
512_L	517_P	0.508	0.50
104_V	335_D	0.507	0.50
427_L	435_D	0.507	0.50
232_E	235_Q	0.507	0.50
251_A	255_L	0.506	0.49
251_A	259_L	0.506	0.49
228_T	233_P	0.506	0.49
169_R	182_T	0.506	0.49
348_L	351_K	0.505	0.49
15_L	18_L	0.505	0.49
394_L	481_L	0.504	0.49
248_D	253_F	0.504	0.49
222_G	228_T	0.504	0.49
218_D	240_T	0.504	0.49
533_A	553_L	0.504	0.49
19_L	22_L	0.503	0.49
531_G	535_L	0.502	0.49
427_L	437_L	0.502	0.49
26_V	30_D	0.502	0.49
244_L	252_P	0.501	0.49
92_V	109_I	0.501	0.49
23_V	160_I	0.501	0.49
597_T	602_V	0.501	0.49
46_T	84_F	0.500	0.49
29_F	32_N	0.500	0.49
25_L	33_D	0.500	0.49

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pj0U	1	0.1398	30.5	0.966	Contact Map
4um9B	2	0	17.3	0.97	Contact Map
2lk9A	1	0.0395	8.6	0.974	Contact Map
5a2fA	1	0	7.9	0.974	Contact Map
1m56D	1	0.0395	5.8	0.976	Contact Map
2m3eA	1	0.0674	5.3	0.976	Contact Map
4xtrG	1	0.0362	4.7	0.977	Contact Map
1pfiA	7	0.0461	4.7	0.977	Contact Map
2kncA	1	0.0707	4.6	0.977	Contact Map
3hd7A	1	0.051	4.5	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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