ResB - PFAM28P - GREMLIN Contacts

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ResB - ResB-like family

PFAM:	PF05140	Sequences: MRTALVLLLLLALAAIPGTLLPQRSPDPNYVAQYFADGPFLAPVLDRLGLFDVYSSWWFSAIYLLLFVSLIGCILPRTPKHWRALRSARPPRAPRRLRRLPHHAEWTVAASPEEALARARALLRRRGYRVRRREDDGGTSVAAEKGYLRELGNLVFHLALVVILVGGALGGLFGFRGNVIVVEGETFSNTLLDSFRPGRLVDGLPFSVRLDDFTAEYYPTGQPKDFASDVTVTDGGGEVREATIRVNHPLRYGGVRVYQSGFGDGGKLKLKAWPLDGGSAKPFELEGTVSTPLTLGGYAPVFTVRDPDGEVVFMGPVPQDGNFTSSGVRKPQLGFRGLFLPTAALDGVGGFLSLFPALNNPALALEAYRGDLGLDSGRPQSVYSLDTSRFEQGALNALLFNYGAPVLLQLPDFDVVQWSGLQVSRDPGQPWVLLGALLLLLGLFLSLYVRRRRVWVRVTTVVEVAGLARRDDAGFEREFE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	480 (445)
Sequences:	3844 (2643)
Seq/√Len:	125.3
META:	0.642

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
211_D	231_T	5.676	1.00
35_F	42_A	4.625	1.00
120_R	132_R	4.591	1.00
245_R	248_H	3.840	1.00
214_T	229_D	3.805	1.00
162_V	435_G	3.669	1.00
402_Y	405_P	3.499	1.00
358_L	415_V	3.260	1.00
111_S	114_E	3.191	1.00
45_L	50_L	3.152	1.00
405_P	409_Q	3.082	1.00
227_A	243_T	3.031	1.00
49_G	57_W	2.979	1.00
230_V	244_I	2.922	1.00
302_F	363_L	2.915	1.00
211_D	241_E	2.887	1.00
119_A	456_V	2.785	1.00
251_R	256_R	2.742	1.00
430_P	434_L	2.740	1.00
105_E	461_V	2.685	1.00
117_A	132_R	2.676	1.00
166_G	431_W	2.585	1.00
405_P	408_L	2.581	1.00
227_A	245_R	2.519	1.00
33_Q	37_D	2.511	1.00
89_R	131_R	2.511	1.00
229_D	243_T	2.482	1.00
313_F	317_V	2.462	1.00
302_F	329_R	2.460	1.00
234_D	253_G	2.379	1.00
208_V	257_V	2.359	1.00
22_P	25_S	2.294	1.00
218_Y	224_K	2.276	1.00
15_A	59_F	2.267	1.00
212_D	229_D	2.158	1.00
210_L	419_S	2.145	1.00
209_R	231_T	2.144	1.00
225_D	245_R	2.132	1.00
50_L	53_V	2.130	1.00
303_T	414_D	2.105	1.00
186_T	209_R	2.103	1.00
44_V	47_R	2.088	1.00
231_T	241_E	2.078	1.00
74_I	161_V	2.027	1.00
402_Y	406_V	2.019	1.00
130_V	141_V	2.007	1.00
52_D	55_S	1.990	1.00
110_A	115_A	1.980	1.00
132_R	141_V	1.978	1.00
67_F	164_L	1.955	1.00
390_F	393_G	1.946	1.00
373_G	377_G	1.943	1.00
79_P	83_R	1.942	1.00
110_A	118_R	1.940	1.00
40_F	44_V	1.925	1.00
410_L	413_F	1.887	1.00
244_I	421_L	1.856	1.00
114_E	117_A	1.840	1.00
229_D	241_E	1.838	1.00
159_A	438_L	1.837	1.00
112_P	460_T	1.834	1.00
209_R	233_T	1.832	1.00
14_A	58_W	1.798	1.00
166_G	432_V	1.796	1.00
260_S	420_G	1.777	1.00
166_G	435_G	1.775	1.00
404_A	407_L	1.755	1.00
183_E	210_L	1.750	1.00
242_A	248_H	1.740	1.00
403_G	406_V	1.734	1.00
81_H	151_L	1.682	1.00
113_E	117_A	1.677	1.00
402_Y	407_L	1.672	1.00
44_V	48_L	1.665	1.00
30_Y	33_Q	1.653	1.00
24_R	46_D	1.648	1.00
117_A	121_A	1.647	1.00
392_Q	395_L	1.635	1.00
301_V	316_P	1.630	1.00
49_G	56_S	1.622	1.00
181_V	421_L	1.619	1.00
74_I	158_L	1.616	1.00
214_T	227_A	1.615	1.00
98_R	105_E	1.587	1.00
107_T	461_V	1.580	1.00
404_A	409_Q	1.575	1.00
475_F	479_F	1.573	1.00
155_V	445_L	1.555	1.00
105_E	463_E	1.553	1.00
403_G	407_L	1.551	1.00
219_P	359_N	1.550	1.00
324_T	342_T	1.546	1.00
4_A	73_C	1.525	1.00
78_T	82_W	1.524	1.00
100_L	465_A	1.524	1.00
116_L	120_R	1.497	1.00
342_T	355_F	1.485	1.00
17_P	50_L	1.473	1.00
210_L	228_S	1.472	1.00
93_A	140_S	1.468	1.00
35_F	46_D	1.462	1.00
213_F	419_S	1.462	1.00
183_E	416_V	1.459	1.00
230_V	242_A	1.448	1.00
228_S	259_Q	1.438	1.00
261_G	420_G	1.435	1.00
116_L	458_V	1.433	1.00
57_W	61_A	1.433	1.00
45_L	51_F	1.427	1.00
123_L	143_A	1.421	1.00
82_W	85_L	1.420	1.00
208_V	421_L	1.419	1.00
406_V	409_Q	1.415	1.00
78_T	158_L	1.411	1.00
14_A	62_I	1.408	1.00
300_P	307_P	1.404	1.00
134_E	137_G	1.395	1.00
43_P	47_R	1.383	1.00
402_Y	409_Q	1.375	1.00
297_G	300_P	1.370	1.00
303_T	314_M	1.362	1.00
232_V	240_R	1.349	1.00
115_A	460_T	1.347	1.00
110_A	114_E	1.347	1.00
122_L	126_R	1.337	1.00
233_T	237_G	1.334	1.00
437_L	441_L	1.333	1.00
181_V	187_F	1.333	1.00
390_F	395_L	1.332	1.00
244_I	250_L	1.324	1.00
452_R	478_E	1.317	1.00
230_V	250_L	1.313	1.00
306_D	310_E	1.311	1.00
393_G	396_N	1.310	1.00
466_G	475_F	1.310	1.00
34_Y	45_L	1.308	1.00
340_L	343_A	1.293	1.00
298_Y	302_F	1.272	1.00
166_G	428_G	1.262	1.00
97_L	465_A	1.261	1.00
343_A	362_A	1.258	1.00
24_R	52_D	1.254	1.00
39_P	43_P	1.253	1.00
212_D	417_Q	1.251	1.00
444_F	448_Y	1.246	1.00
25_S	29_N	1.238	1.00
34_Y	42_A	1.226	0.99
179_V	187_F	1.226	0.99
11_L	66_L	1.226	0.99
391_E	394_A	1.218	0.99
313_F	316_P	1.214	0.99
232_V	252_Y	1.213	0.99
404_A	408_L	1.212	0.99
232_V	250_L	1.211	0.99
46_D	51_F	1.205	0.99
57_W	60_S	1.198	0.99
390_F	394_A	1.197	0.99
1_M	8_L	1.192	0.99
401_N	405_P	1.185	0.99
254_G	425_R	1.182	0.99
262_F	323_F	1.180	0.99
257_V	423_V	1.175	0.99
41_L	45_L	1.163	0.99
74_I	78_T	1.160	0.99
116_L	132_R	1.154	0.99
375_D	378_R	1.151	0.99
392_Q	396_N	1.147	0.99
208_V	232_V	1.146	0.99
132_R	139_T	1.143	0.99
300_P	304_V	1.143	0.99
170_G	426_D	1.140	0.99
71_I	161_V	1.127	0.99
215_A	417_Q	1.125	0.99
394_A	398_L	1.119	0.99
218_Y	222_Q	1.119	0.99
26_P	29_N	1.115	0.99
459_T	463_E	1.114	0.99
30_Y	38_G	1.112	0.99
301_V	416_V	1.106	0.99
232_V	242_A	1.095	0.99
54_Y	435_G	1.091	0.99
346_D	350_G	1.088	0.99
35_F	39_P	1.086	0.99
355_F	359_N	1.077	0.99
5_L	9_L	1.076	0.99
30_Y	37_D	1.073	0.99
121_A	125_R	1.067	0.99
259_Q	419_S	1.063	0.98
81_H	154_L	1.063	0.98
339_F	342_T	1.062	0.98
216_E	225_D	1.062	0.98
120_R	141_V	1.061	0.98
152_G	442_G	1.058	0.98
216_E	224_K	1.056	0.98
223_P	226_F	1.055	0.98
230_V	421_L	1.054	0.98
319_Q	323_F	1.052	0.98
82_W	86_R	1.051	0.98
445_L	449_V	1.050	0.98
214_T	243_T	1.047	0.98
305_R	311_V	1.047	0.98
242_A	250_L	1.047	0.98
340_L	351_F	1.046	0.98
312_V	315_G	1.045	0.98
314_M	317_V	1.039	0.98
236_G	253_G	1.037	0.98
32_A	36_A	1.034	0.98
27_D	30_Y	1.032	0.98
401_N	407_L	1.031	0.98
389_R	392_Q	1.028	0.98
234_D	237_G	1.028	0.98
67_F	160_L	1.027	0.98
400_F	403_G	1.024	0.98
175_F	255_V	1.024	0.98
97_L	103_H	1.021	0.98
373_G	376_S	1.020	0.98
126_R	478_E	1.011	0.98
435_G	438_L	1.007	0.98
210_L	421_L	1.007	0.98
135_D	138_G	1.007	0.98
403_G	408_L	1.001	0.98
301_V	312_V	1.000	0.98
31_V	34_Y	0.992	0.98
102_H	476_E	0.991	0.98
56_S	60_S	0.990	0.98
233_T	239_V	0.987	0.98
403_G	409_Q	0.983	0.97
21_L	41_L	0.982	0.97
346_D	352_L	0.980	0.97
60_S	64_L	0.979	0.97
103_H	463_E	0.978	0.97
401_N	404_A	0.978	0.97
401_N	406_V	0.973	0.97
53_V	58_W	0.971	0.97
85_L	151_L	0.971	0.97
207_S	233_T	0.970	0.97
458_V	462_V	0.969	0.97
144_E	147_Y	0.966	0.97
399_L	402_Y	0.965	0.97
71_I	75_L	0.959	0.97
116_L	139_T	0.956	0.97
81_H	85_L	0.955	0.97
42_A	46_D	0.955	0.97
42_A	50_L	0.949	0.97
74_I	154_L	0.948	0.97
26_P	30_Y	0.947	0.97
98_R	463_E	0.943	0.97
159_A	439_L	0.942	0.97
381_S	385_L	0.940	0.97
211_D	229_D	0.938	0.97
79_P	82_W	0.938	0.97
81_H	84_A	0.933	0.97
174_G	428_G	0.933	0.97
40_F	43_P	0.931	0.96
204_L	253_G	0.931	0.96
368_Y	372_L	0.928	0.96
112_P	458_V	0.928	0.96
118_R	122_L	0.922	0.96
7_L	66_L	0.921	0.96
306_D	309_G	0.917	0.96
3_T	69_S	0.916	0.96
66_L	69_S	0.915	0.96
381_S	384_S	0.915	0.96
456_V	464_V	0.914	0.96
361_P	365_L	0.901	0.96
346_D	351_F	0.898	0.96
234_D	252_Y	0.897	0.96
181_V	186_T	0.893	0.96
117_A	120_R	0.889	0.95
389_R	395_L	0.889	0.95
441_L	445_L	0.885	0.95
186_T	207_S	0.884	0.95
332_Q	335_F	0.883	0.95
213_F	262_F	0.878	0.95
114_E	118_R	0.875	0.95
351_F	364_A	0.870	0.95
134_E	139_T	0.870	0.95
374_L	378_R	0.868	0.95
344_A	354_L	0.866	0.95
30_Y	34_Y	0.865	0.95
29_N	32_A	0.865	0.95
471_D	474_G	0.864	0.95
262_F	417_Q	0.864	0.95
182_V	299_A	0.862	0.95
307_P	312_V	0.862	0.95
339_F	415_V	0.859	0.94
433_L	437_L	0.858	0.94
389_R	393_G	0.856	0.94
433_L	436_A	0.853	0.94
133_R	140_S	0.852	0.94
119_A	458_V	0.849	0.94
169_L	173_F	0.845	0.94
191_L	195_F	0.845	0.94
88_A	142_A	0.841	0.94
348_V	352_L	0.841	0.94
297_G	302_F	0.841	0.94
120_R	130_V	0.840	0.94
319_Q	326_S	0.838	0.94
380_Q	384_S	0.836	0.94
357_A	417_Q	0.834	0.94
154_L	158_L	0.834	0.94
166_G	174_G	0.829	0.93
431_W	434_L	0.828	0.93
4_A	70_L	0.827	0.93
377_G	381_S	0.827	0.93
21_L	45_L	0.826	0.93
21_L	50_L	0.825	0.93
29_N	33_Q	0.824	0.93
108_V	460_T	0.822	0.93
14_A	53_V	0.821	0.93
325_S	329_R	0.820	0.93
156_F	443_L	0.818	0.93
70_L	73_C	0.818	0.93
345_L	351_F	0.818	0.93
240_R	252_Y	0.817	0.93
176_R	422_Q	0.814	0.93
355_F	362_A	0.814	0.93
162_V	438_L	0.814	0.93
115_A	462_V	0.812	0.93
182_V	185_E	0.810	0.93
163_I	435_G	0.808	0.92
336_R	387_T	0.807	0.92
58_W	62_I	0.807	0.92
434_L	438_L	0.806	0.92
299_A	302_F	0.804	0.92
323_F	327_G	0.804	0.92
3_T	7_L	0.803	0.92
13_L	17_P	0.800	0.92
339_F	343_A	0.798	0.92
120_R	124_R	0.797	0.92
144_E	451_R	0.796	0.92
180_I	420_G	0.794	0.92
24_R	35_F	0.794	0.92
217_Y	417_Q	0.794	0.92
208_V	419_S	0.792	0.92
353_S	361_P	0.791	0.92
30_Y	35_F	0.784	0.91
464_V	479_F	0.781	0.91
234_D	240_R	0.780	0.91
376_S	380_Q	0.779	0.91
234_D	238_E	0.777	0.91
134_E	138_G	0.773	0.91
457_R	463_E	0.771	0.91
374_L	377_G	0.770	0.91
254_G	427_P	0.770	0.91
38_G	43_P	0.770	0.91
179_V	182_V	0.768	0.90
391_E	395_L	0.767	0.90
338_L	343_A	0.765	0.90
325_S	328_V	0.763	0.90
391_E	398_L	0.761	0.90
318_P	322_N	0.759	0.90
378_R	383_Y	0.759	0.90
108_V	458_V	0.759	0.90
165_V	169_L	0.758	0.90
374_L	381_S	0.758	0.90
28_P	31_V	0.758	0.90
232_V	248_H	0.758	0.90
178_N	422_Q	0.757	0.90
73_C	250_L	0.755	0.90
94_P	459_T	0.753	0.90
419_S	448_Y	0.752	0.90
333_L	337_G	0.752	0.90
128_Y	478_E	0.751	0.89
238_E	241_E	0.750	0.89
166_G	224_K	0.750	0.89
191_L	203_G	0.748	0.89
465_A	475_F	0.748	0.89
366_E	369_R	0.746	0.89
379_P	382_V	0.745	0.89
67_F	161_V	0.744	0.89
188_S	207_S	0.744	0.89
116_L	456_V	0.743	0.89
47_R	320_D	0.743	0.89
260_S	422_Q	0.741	0.89
344_A	352_L	0.739	0.89
117_A	124_R	0.736	0.88
12_A	16_I	0.735	0.88
119_A	141_V	0.733	0.88
402_Y	408_L	0.732	0.88
102_H	479_F	0.731	0.88
136_D	139_T	0.729	0.88
169_L	431_W	0.729	0.88
139_T	458_V	0.725	0.88
349_G	352_L	0.725	0.88
450_R	472_D	0.723	0.88
213_F	226_F	0.718	0.87
115_A	458_V	0.715	0.87
426_D	468_A	0.715	0.87
108_V	114_E	0.714	0.87
35_F	38_G	0.714	0.87
109_A	112_P	0.712	0.87
174_G	426_D	0.712	0.87
119_A	122_L	0.710	0.87
324_T	327_G	0.709	0.87
330_K	333_L	0.708	0.86
54_Y	152_G	0.707	0.86
473_A	477_R	0.705	0.86
344_A	360_N	0.704	0.86
106_W	462_V	0.702	0.86
75_L	79_P	0.700	0.86
63_Y	167_G	0.698	0.86
473_A	476_E	0.697	0.86
258_Y	424_S	0.695	0.85
155_V	438_L	0.692	0.85
170_G	436_A	0.692	0.85
70_L	74_I	0.691	0.85
25_S	30_Y	0.691	0.85
451_R	469_R	0.691	0.85
160_L	164_L	0.688	0.85
342_T	354_L	0.684	0.85
150_E	153_N	0.683	0.84
389_R	394_A	0.676	0.84
359_N	362_A	0.675	0.84
304_V	308_D	0.674	0.84
41_L	44_V	0.674	0.84
146_G	449_V	0.671	0.83
181_V	210_L	0.671	0.83
302_F	313_F	0.669	0.83
388_S	391_E	0.668	0.83
123_L	456_V	0.664	0.83
320_D	324_T	0.664	0.83
183_E	417_Q	0.662	0.83
43_P	46_D	0.661	0.83
166_G	176_R	0.660	0.82
15_A	54_Y	0.660	0.82
183_E	212_D	0.660	0.82
257_V	421_L	0.659	0.82
100_L	103_H	0.658	0.82
335_F	340_L	0.657	0.82
34_Y	426_D	0.656	0.82
431_W	436_A	0.656	0.82
1_M	76_P	0.654	0.82
387_T	390_F	0.652	0.82
118_R	121_A	0.649	0.81
428_G	432_V	0.648	0.81
118_R	124_R	0.646	0.81
31_V	35_F	0.646	0.81
4_A	72_G	0.645	0.81
54_Y	222_Q	0.641	0.81
122_L	125_R	0.640	0.80
345_L	350_G	0.638	0.80
34_Y	38_G	0.633	0.80
158_L	161_V	0.633	0.80
145_K	454_V	0.632	0.80
70_L	76_P	0.632	0.80
182_V	416_V	0.631	0.80
329_R	335_F	0.631	0.80
208_V	230_V	0.631	0.80
206_F	255_V	0.630	0.79
178_N	260_S	0.629	0.79
162_V	166_G	0.629	0.79
174_G	444_F	0.625	0.79
297_G	305_R	0.623	0.79
6_V	9_L	0.623	0.79
217_Y	223_P	0.621	0.78
98_R	121_A	0.621	0.78
99_R	103_H	0.620	0.78
7_L	10_L	0.620	0.78
146_G	152_G	0.619	0.78
49_G	52_D	0.619	0.78
87_S	90_P	0.617	0.78
175_F	420_G	0.617	0.78
236_G	239_V	0.616	0.78
366_E	370_G	0.615	0.78
126_R	145_K	0.614	0.78
100_L	467_L	0.613	0.78
158_L	162_V	0.612	0.77
230_V	419_S	0.612	0.77
371_D	374_L	0.611	0.77
309_G	312_V	0.610	0.77
96_R	100_L	0.609	0.77
350_G	355_F	0.609	0.77
426_D	432_V	0.607	0.77
113_E	132_R	0.606	0.77
171_G	176_R	0.605	0.77
367_A	370_G	0.603	0.76
393_G	398_L	0.602	0.76
163_I	436_A	0.602	0.76
166_G	169_L	0.599	0.76
366_E	394_A	0.598	0.76
91_P	443_L	0.598	0.76
213_F	246_V	0.597	0.76
432_V	436_A	0.597	0.76
5_L	66_L	0.596	0.76
131_R	142_A	0.595	0.75
436_A	440_L	0.594	0.75
315_G	329_R	0.594	0.75
8_L	153_N	0.594	0.75
76_P	150_E	0.593	0.75
322_N	346_D	0.592	0.75
35_F	41_L	0.591	0.75
301_V	304_V	0.591	0.75
59_F	66_L	0.591	0.75
34_Y	41_L	0.589	0.75
106_W	115_A	0.589	0.75
372_L	376_S	0.589	0.75
84_A	151_L	0.588	0.75
399_L	405_P	0.586	0.74
1_M	4_A	0.586	0.74
332_Q	373_G	0.586	0.74
228_S	419_S	0.585	0.74
301_V	314_M	0.584	0.74
70_L	91_P	0.584	0.74
37_D	105_E	0.583	0.74
116_L	130_V	0.583	0.74
21_L	24_R	0.583	0.74
18_G	23_Q	0.583	0.74
357_A	363_L	0.582	0.74
128_Y	452_R	0.581	0.74
220_T	355_F	0.581	0.74
210_L	230_V	0.581	0.74
115_A	119_A	0.580	0.74
343_A	351_F	0.580	0.74
298_Y	304_V	0.580	0.74
426_D	436_A	0.580	0.74
301_V	414_D	0.579	0.73
431_W	435_G	0.577	0.73
123_L	127_G	0.577	0.73
133_R	136_D	0.576	0.73
304_V	309_G	0.576	0.73
435_G	442_G	0.576	0.73
370_G	373_G	0.575	0.73
206_F	446_S	0.574	0.73
353_S	356_P	0.573	0.73
340_L	344_A	0.573	0.73
15_A	19_T	0.572	0.73
355_F	466_G	0.572	0.73
42_A	51_F	0.572	0.73
140_S	456_V	0.572	0.73
255_V	425_R	0.571	0.72
448_Y	455_W	0.571	0.72
63_Y	72_G	0.571	0.72
307_P	310_E	0.570	0.72
167_G	171_G	0.570	0.72
108_V	111_S	0.569	0.72
147_Y	150_E	0.569	0.72
179_V	208_V	0.569	0.72
20_L	143_A	0.568	0.72
470_R	476_E	0.568	0.72
312_V	317_V	0.567	0.72
177_G	192_L	0.567	0.72
144_E	453_R	0.567	0.72
31_V	39_P	0.565	0.72
298_Y	305_R	0.565	0.72
235_G	239_V	0.565	0.72
382_V	386_D	0.564	0.72
475_F	478_E	0.564	0.72
116_L	119_A	0.564	0.72
217_Y	323_F	0.563	0.71
112_P	115_A	0.563	0.71
335_F	367_A	0.561	0.71
232_V	244_I	0.561	0.71
156_F	167_G	0.561	0.71
434_L	437_L	0.561	0.71
111_S	231_T	0.560	0.71
106_W	459_T	0.560	0.71
159_A	194_S	0.559	0.71
66_L	73_C	0.559	0.71
369_R	393_G	0.558	0.71
472_D	475_F	0.558	0.71
73_C	213_F	0.557	0.71
354_L	362_A	0.557	0.71
150_E	451_R	0.557	0.71
93_A	96_R	0.557	0.71
333_L	336_R	0.556	0.70
223_P	262_F	0.556	0.70
474_G	477_R	0.555	0.70
347_G	412_D	0.554	0.70
1_M	69_S	0.554	0.70
399_L	404_A	0.554	0.70
353_S	363_L	0.554	0.70
198_G	201_V	0.552	0.70
236_G	240_R	0.552	0.70
407_L	411_P	0.551	0.70
369_R	372_L	0.550	0.70
145_K	470_R	0.550	0.70
22_P	150_E	0.550	0.70
327_G	330_K	0.549	0.70
435_G	470_R	0.549	0.70
141_V	458_V	0.548	0.69
215_A	226_F	0.548	0.69
388_S	392_Q	0.547	0.69
8_L	146_G	0.545	0.69
11_L	62_I	0.544	0.69
170_G	429_Q	0.543	0.69
35_F	50_L	0.542	0.69
90_P	131_R	0.542	0.69
344_A	348_V	0.541	0.68
173_F	427_P	0.540	0.68
358_L	361_P	0.540	0.68
79_P	142_A	0.540	0.68
400_F	408_L	0.538	0.68
369_R	411_P	0.537	0.68
21_L	42_A	0.536	0.68
68_V	78_T	0.536	0.68
433_L	447_L	0.536	0.68
246_V	259_Q	0.535	0.68
215_A	262_F	0.535	0.68
231_T	239_V	0.535	0.68
56_S	61_A	0.535	0.68
350_G	362_A	0.534	0.67
92_R	128_Y	0.533	0.67
151_L	155_V	0.533	0.67
12_A	163_I	0.531	0.67
10_L	34_Y	0.530	0.67
123_L	454_V	0.530	0.67
428_G	431_W	0.530	0.67
1_M	154_L	0.530	0.67
373_G	378_R	0.529	0.67
370_G	374_L	0.529	0.67
155_V	159_A	0.528	0.67
319_Q	322_N	0.528	0.67
331_P	374_L	0.528	0.67
360_N	365_L	0.528	0.67
75_L	78_T	0.527	0.66
14_A	123_L	0.525	0.66
158_L	447_L	0.525	0.66
233_T	241_E	0.524	0.66
420_G	423_V	0.522	0.66
341_P	345_L	0.522	0.66
10_L	14_A	0.522	0.66
24_R	38_G	0.521	0.66
175_F	425_R	0.521	0.66
24_R	45_L	0.520	0.65
349_G	360_N	0.520	0.65
76_P	154_L	0.520	0.65
67_F	71_I	0.520	0.65
181_V	223_P	0.519	0.65
113_E	120_R	0.519	0.65
91_P	140_S	0.519	0.65
223_P	417_Q	0.518	0.65
159_A	428_G	0.517	0.65
209_R	239_V	0.516	0.65
82_W	151_L	0.516	0.65
167_G	170_G	0.516	0.65
366_E	397_A	0.515	0.65
218_Y	223_P	0.515	0.65
216_E	227_A	0.514	0.65
347_G	351_F	0.514	0.65
299_A	312_V	0.512	0.64
468_A	475_F	0.510	0.64
364_A	367_A	0.509	0.64
383_Y	386_D	0.509	0.64
323_F	326_S	0.509	0.64
31_V	38_G	0.509	0.64
38_G	71_I	0.508	0.64
158_L	438_L	0.508	0.64
428_G	439_L	0.508	0.64
1_M	72_G	0.507	0.63
109_A	236_G	0.507	0.63
104_A	245_R	0.506	0.63
474_G	478_E	0.506	0.63
400_F	404_A	0.506	0.63
39_P	130_V	0.505	0.63
25_S	34_Y	0.505	0.63
470_R	475_F	0.505	0.63
86_R	347_G	0.505	0.63
466_G	472_D	0.505	0.63
148_L	151_L	0.504	0.63
261_G	418_W	0.504	0.63
355_F	358_L	0.503	0.63
423_V	458_V	0.503	0.63
104_A	479_F	0.502	0.63
154_L	226_F	0.502	0.63
392_Q	398_L	0.502	0.63
63_Y	298_Y	0.501	0.63
93_A	232_V	0.500	0.62

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2akhX	1	0.1583	33.6	0.971	Contact Map
4wfeA	2	0.1688	29.7	0.972	Contact Map
3dl8E	1	0.1333	27.1	0.972	Contact Map
3dinE	1	0.1292	19.5	0.974	Contact Map
4ltoA	3	0.2458	19.4	0.974	Contact Map
2zy9A	2	0.1292	18.4	0.975	Contact Map
4twkA	2	0.1812	16.5	0.975	Contact Map
4h33A	3	0.1729	12.6	0.976	Contact Map
3vouA	4	0.2271	12.3	0.976	Contact Map
1jqkA	3	0.2208	11.6	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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