GREMLIN Database
Phage_tail_L - Phage minor tail protein L
PFAM: PF05100 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 206 (201)
Sequences: 1482 (1061)
Seq/√Len: 74.8
META: 0.721

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
179_G184_S6.7561.00
164_D168_N4.9591.00
167_D184_S4.5181.00
35_A38_F3.9681.00
34_E52_T3.9281.00
20_S30_P3.4971.00
22_V27_T3.2831.00
9_R26_N3.2621.00
52_T121_E3.1741.00
111_R123_E3.0581.00
98_D101_A2.9921.00
50_T121_E2.6021.00
160_T163_F2.5341.00
78_R104_D2.5141.00
164_D170_T2.4691.00
140_I203_A2.3421.00
181_R184_S2.2971.00
172_D175_L2.2231.00
22_V88_V2.2071.00
69_D112_K2.1521.00
74_K108_Y2.1281.00
52_T119_V2.0981.00
16_E91_P2.0631.00
20_S27_T2.0621.00
24_Q78_R2.0521.00
48_R123_E1.9531.00
60_I120_V1.9301.00
64_C120_V1.9051.00
64_C122_F1.8751.00
165_E177_V1.8381.00
80_T84_Y1.8051.00
38_F77_R1.8011.00
167_D181_R1.7691.00
167_D179_G1.6901.00
133_V137_R1.6751.00
33_I51_L1.6731.00
41_S47_P1.6611.00
152_G156_G1.6531.00
110_D125_A1.6070.99
61_T65_L1.5800.99
170_T175_L1.5560.99
190_G193_N1.5510.99
186_K191_E1.5350.99
146_P199_G1.4980.99
138_R146_P1.4910.99
190_G195_L1.4710.99
36_E52_T1.4530.99
109_I122_F1.4480.99
75_V109_I1.4460.99
184_S187_L1.4350.99
89_N94_N1.4240.99
20_S29_T1.3930.99
112_K115_E1.3690.98
150_Y188_R1.3380.98
193_N196_P1.3200.98
76_T106_I1.3070.98
35_A51_L1.3010.98
23_W102_E1.2990.98
147_W198_G1.2970.98
94_N97_A1.2740.97
78_R102_E1.2610.97
163_F170_T1.2570.97
186_K192_N1.2470.97
182_L186_K1.2370.97
51_L75_V1.2280.97
60_I122_F1.2250.97
184_S188_R1.2160.97
108_Y127_P1.2040.96
74_K106_I1.1540.95
179_G187_L1.1300.95
150_Y176_D1.1250.95
90_F94_N1.1200.94
180_K184_S1.1110.94
190_G196_P1.1100.94
37_G49_P1.1040.94
162_Y170_T1.1040.94
51_L124_L1.1010.94
195_L201_P1.0930.94
197_F201_P1.0900.94
151_R157_Y1.0820.93
14_T17_L1.0530.92
54_S57_D1.0280.91
98_D103_F1.0130.91
183_S187_L1.0090.91
35_A77_R1.0080.91
40_M105_E0.9940.90
182_L201_P0.9830.90
138_R147_W0.9830.90
53_V60_I0.9820.90
156_G196_P0.9800.89
76_T104_D0.9790.89
61_T115_E0.9700.89
24_Q102_E0.9690.89
32_P108_Y0.9680.89
113_T123_E0.9550.88
165_E168_N0.9520.88
23_W78_R0.9400.87
77_R105_E0.9390.87
171_T175_L0.9360.87
163_F187_L0.9190.86
114_S121_E0.8960.85
13_G18_G0.8960.85
178_C185_C0.8950.85
147_W154_E0.8920.84
178_C188_R0.8860.84
185_C188_R0.8810.84
164_D175_L0.8690.83
69_D81_L0.8660.83
8_L63_L0.8640.83
50_T113_T0.8620.82
38_F107_Y0.8550.82
113_T121_E0.8530.82
97_A101_A0.8530.82
21_I88_V0.8510.82
63_L92_G0.8460.81
176_D188_R0.8430.81
15_N48_R0.8410.81
116_N119_V0.8310.80
183_S186_K0.8170.79
12_A15_N0.8160.79
88_V93_G0.8140.79
13_G48_R0.8100.78
49_P77_R0.8070.78
23_W28_Y0.7930.77
72_G110_D0.7900.77
151_R156_G0.7900.77
46_L128_L0.7850.76
87_A90_F0.7800.76
36_E50_T0.7790.76
114_S119_V0.7750.75
79_R105_E0.7690.75
189_F196_P0.7660.74
31_W54_S0.7650.74
110_D131_E0.7600.74
100_T103_F0.7540.73
179_G188_R0.7540.73
161_P173_P0.7530.73
115_E120_V0.7520.73
37_G50_T0.7430.72
86_D94_N0.7380.72
110_D130_L0.7340.71
169_P172_D0.7330.71
138_R200_F0.7260.70
53_V122_F0.7240.70
191_E194_P0.7140.69
20_S31_W0.7120.69
31_W53_V0.7110.69
160_T170_T0.6970.67
178_C184_S0.6970.67
163_F169_P0.6960.67
32_P56_V0.6950.67
65_L120_V0.6930.67
55_N116_N0.6920.67
55_N61_T0.6920.67
59_L62_A0.6880.66
157_Y176_D0.6880.66
196_P200_F0.6880.66
148_C180_K0.6870.66
81_L129_D0.6870.66
61_T140_I0.6850.66
61_T120_V0.6840.66
14_T19_G0.6830.66
65_L80_T0.6810.65
70_L75_V0.6790.65
58_G116_N0.6780.65
97_A107_Y0.6780.65
79_R83_K0.6760.65
177_V188_R0.6750.65
96_T100_T0.6740.65
12_A152_G0.6710.64
69_D115_E0.6680.64
108_Y130_L0.6660.64
25_G87_A0.6630.63
39_E107_Y0.6630.63
128_L135_L0.6590.63
196_P201_P0.6570.63
20_S68_D0.6540.62
63_L67_Y0.6530.62
189_F193_N0.6510.62
41_S46_L0.6490.62
153_A156_G0.6480.62
8_L161_P0.6470.61
146_P198_G0.6470.61
8_L64_C0.6460.61
163_F168_N0.6410.61
75_V85_L0.6410.61
24_Q99_P0.6400.61
16_E19_G0.6390.60
144_V199_G0.6350.60
46_L126_S0.6350.60
83_K96_T0.6340.60
72_G136_P0.6320.60
159_G162_Y0.6310.59
105_E131_E0.6310.59
110_D139_Q0.6270.59
115_E129_D0.6260.59
23_W90_F0.6260.59
11_H18_G0.6260.59
32_P136_P0.6250.59
122_F127_P0.6220.58
67_Y166_N0.6210.58
87_A94_N0.6160.58
141_I144_V0.6150.58
31_W60_I0.6130.57
179_G183_S0.6110.57
47_P111_R0.6100.57
95_P113_T0.6090.57
176_D184_S0.6090.57
115_E154_E0.6080.57
177_V181_R0.6020.56
169_P173_P0.6010.56
160_T187_L0.5990.56
22_V89_N0.5960.55
163_F167_D0.5950.55
11_H151_R0.5950.55
112_K120_V0.5930.55
178_C181_R0.5930.55
93_G97_A0.5930.55
87_A93_G0.5920.55
116_N121_E0.5910.55
12_A63_L0.5890.54
76_T84_Y0.5890.54
81_L118_E0.5870.54
74_K133_V0.5860.54
93_G98_D0.5850.54
90_F98_D0.5820.53
39_E196_P0.5800.53
57_D109_I0.5800.53
93_G159_G0.5780.53
39_E42_G0.5780.53
33_I111_R0.5780.53
43_D144_V0.5770.53
162_Y172_D0.5770.53
129_D133_V0.5760.53
146_P152_G0.5740.52
7_V76_T0.5740.52
180_K185_C0.5730.52
97_A102_E0.5680.52
175_L188_R0.5680.52
182_L187_L0.5660.51
47_P105_E0.5660.51
36_E119_V0.5650.51
81_L133_V0.5640.51
178_C182_L0.5640.51
143_N180_K0.5630.51
47_P126_S0.5620.51
54_S64_C0.5620.51
39_E47_P0.5620.51
177_V180_K0.5600.51
73_A140_I0.5590.51
161_P170_T0.5580.50
148_C197_F0.5530.50
113_T119_V0.5530.50
110_D142_A0.5530.50
186_K193_N0.5520.50
86_D89_N0.5490.49
39_E115_E0.5480.49
51_L109_I0.5480.49
79_R117_K0.5430.49
162_Y171_T0.5430.49
77_R83_K0.5420.48
40_M61_T0.5410.48
86_D90_F0.5410.48
149_R156_G0.5400.48
72_G79_R0.5400.48
19_G88_V0.5400.48
42_G133_V0.5380.48
69_D79_R0.5350.48
154_E158_T0.5340.47
9_R42_G0.5330.47
23_W80_T0.5330.47
171_T174_A0.5320.47
87_A97_A0.5320.47
22_V26_N0.5310.47
110_D126_S0.5310.47
41_S68_D0.5300.47
175_L192_N0.5280.47
60_I71_V0.5280.47
11_H14_T0.5260.46
27_T53_V0.5260.46
70_L73_A0.5250.46
182_L194_P0.5230.46
8_L18_G0.5200.46
70_L78_R0.5200.46
94_N125_A0.5170.45
91_P140_I0.5160.45
105_E127_P0.5160.45
50_T100_T0.5160.45
56_V68_D0.5160.45
31_W117_K0.5140.45
55_N120_V0.5130.45
86_D121_E0.5110.45
105_E112_K0.5110.45
60_I109_I0.5080.44
17_L21_I0.5070.44
97_A100_T0.5070.44
4_G8_L0.5040.44
14_T33_I0.5030.44
186_K195_L0.5020.43
99_P174_A0.5020.43
81_L103_F0.5010.43
22_V31_W0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4qiwA 2 0.3932 40.6 0.946 Contact Map
1twfA 1 0.4369 20 0.954 Contact Map
4aybA 1 0.3981 18.1 0.955 Contact Map
3h0gA 2 0.4466 10.1 0.96 Contact Map
2c7hA 1 0.3981 5.2 0.965 Contact Map
4c2mA 1 0.4515 4.9 0.965 Contact Map
4aw7A 1 0.4029 4 0.967 Contact Map
1hqmD 1 0.3155 3.5 0.968 Contact Map
1pmhX 1 0.3495 2.9 0.969 Contact Map
3vnyA 3 0.3107 2.9 0.969 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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