Mak16 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Mak16 - Mak16 protein C-terminal region

PFAM:	PF04874	Sequences: KKKVERREARRERKALAAAKLEKAIEKELLERLKSGTYGDIYNFPEKVWKKVLEEEEEEEEEEEEEEEEEEEEEEEEEEGEVEYVEDDEEEEDLEDLED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	99 (98)
Sequences:	780 (578)
Seq/√Len:	58.4
META:	0.321

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
10_R	13_R	3.606	1.00
58_E	62_E	3.425	1.00
41_I	49_W	3.002	1.00
3_K	7_R	2.613	1.00
21_L	24_A	2.228	1.00
41_I	44_F	2.164	1.00
2_K	5_E	1.994	1.00
46_E	49_W	1.947	1.00
37_T	44_F	1.943	1.00
61_E	64_E	1.930	1.00
94_L	97_L	1.854	1.00
14_K	18_A	1.796	0.99
45_P	49_W	1.754	0.99
91_E	94_L	1.748	0.99
3_K	6_R	1.714	0.99
2_K	6_R	1.668	0.99
72_E	76_E	1.658	0.99
42_Y	49_W	1.636	0.99
60_E	64_E	1.603	0.99
95_E	98_E	1.589	0.99
46_E	50_K	1.566	0.98
16_L	27_K	1.566	0.98
43_N	49_W	1.564	0.98
37_T	40_D	1.520	0.98
12_E	32_R	1.494	0.98
44_F	49_W	1.380	0.96
73_E	77_E	1.358	0.96
2_K	10_R	1.343	0.96
53_L	56_E	1.281	0.95
67_E	75_E	1.280	0.95
81_E	94_L	1.242	0.94
69_E	73_E	1.242	0.94
64_E	69_E	1.232	0.93
52_V	59_E	1.205	0.93
25_I	31_E	1.181	0.92
64_E	68_E	1.154	0.91
8_E	12_E	1.146	0.91
41_I	48_V	1.145	0.91
59_E	64_E	1.142	0.91
67_E	71_E	1.132	0.90
81_E	84_Y	1.096	0.89
25_I	36_G	1.044	0.86
82_V	86_E	1.040	0.86
16_L	25_I	1.033	0.86
91_E	95_E	1.029	0.85
20_K	50_K	1.008	0.84
87_D	90_E	0.998	0.84
42_Y	52_V	0.998	0.84
40_D	53_L	0.990	0.83
34_K	45_P	0.984	0.83
66_E	74_E	0.967	0.82
51_K	57_E	0.964	0.81
17_A	20_K	0.962	0.81
28_E	32_R	0.941	0.80
9_A	56_E	0.935	0.79
60_E	66_E	0.933	0.79
30_L	37_T	0.923	0.78
47_K	50_K	0.919	0.78
14_K	38_Y	0.911	0.77
42_Y	48_V	0.899	0.77
90_E	93_D	0.898	0.76
23_K	49_W	0.897	0.76
43_N	53_L	0.889	0.76
45_P	48_V	0.884	0.75
31_E	34_K	0.884	0.75
17_A	44_F	0.883	0.75
21_L	31_E	0.877	0.75
23_K	38_Y	0.874	0.74
15_A	19_A	0.872	0.74
17_A	48_V	0.868	0.74
26_E	43_N	0.862	0.73
4_V	7_R	0.859	0.73
17_A	23_K	0.852	0.73
6_R	10_R	0.841	0.72
70_E	74_E	0.836	0.71
26_E	51_K	0.832	0.71
21_L	26_E	0.829	0.71
63_E	73_E	0.825	0.70
67_E	70_E	0.798	0.68
6_R	20_K	0.792	0.67
42_Y	45_P	0.782	0.66
70_E	73_E	0.780	0.66
93_D	99_D	0.756	0.63
73_E	79_E	0.755	0.63
81_E	88_D	0.748	0.63
13_R	35_S	0.740	0.62
61_E	65_E	0.734	0.61
20_K	36_G	0.733	0.61
37_T	41_I	0.730	0.61
16_L	22_E	0.723	0.60
18_A	28_E	0.722	0.60
72_E	87_D	0.719	0.59
71_E	75_E	0.715	0.59
22_E	45_P	0.709	0.58
88_D	91_E	0.705	0.58
41_I	45_P	0.704	0.58
89_E	92_E	0.692	0.57
5_E	16_L	0.691	0.56
6_R	48_V	0.685	0.56
9_A	13_R	0.685	0.56
31_E	35_S	0.675	0.55
50_K	57_E	0.673	0.55
11_R	56_E	0.673	0.55
4_V	20_K	0.672	0.54
18_A	32_R	0.671	0.54
58_E	61_E	0.671	0.54
63_E	67_E	0.663	0.53
41_I	52_V	0.658	0.53
7_R	11_R	0.657	0.53
2_K	9_A	0.644	0.51
39_G	44_F	0.641	0.51
3_K	8_E	0.641	0.51
38_Y	44_F	0.638	0.51
46_E	52_V	0.637	0.51
22_E	43_N	0.633	0.50
64_E	71_E	0.630	0.50
22_E	26_E	0.622	0.49
82_V	85_V	0.620	0.49
20_K	37_T	0.618	0.48
45_P	54_E	0.610	0.48
36_G	44_F	0.600	0.46
30_L	39_G	0.600	0.46
40_D	45_P	0.598	0.46
74_E	79_E	0.584	0.45
18_A	27_K	0.579	0.44
9_A	22_E	0.575	0.44
62_E	77_E	0.574	0.44
27_K	31_E	0.567	0.43
68_E	76_E	0.563	0.42
23_K	31_E	0.562	0.42
58_E	66_E	0.562	0.42
12_E	15_A	0.555	0.42
36_G	40_D	0.552	0.41
15_A	36_G	0.536	0.39
31_E	39_G	0.534	0.39
21_L	47_K	0.533	0.39
94_L	98_E	0.529	0.39
36_G	56_E	0.527	0.39
10_R	48_V	0.527	0.39
4_V	36_G	0.524	0.38
36_G	50_K	0.522	0.38
63_E	87_D	0.519	0.38
4_V	39_G	0.517	0.37
89_E	95_E	0.516	0.37
9_A	20_K	0.513	0.37
12_E	33_L	0.509	0.37
47_K	88_D	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4u7aA	1	0	77.1	0.854	Contact Map
4kblA	2	0	42.6	0.884	Contact Map
4fp9B	2	0.5455	18.2	0.903	Contact Map
2ca6A	1	0.4444	6	0.922	Contact Map
3ljcA	1	0.5657	2.8	0.934	Contact Map
4fbnA	1	0.3535	2.7	0.935	Contact Map
4gyiA	1	0.5859	2.4	0.936	Contact Map
4v1nR	1	0	2.4	0.936	Contact Map
1xrsA	2	0.596	2.1	0.938	Contact Map
4ipaA	1	0.0303	1.9	0.939	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0054 seconds.