GREMLIN Database
ATP-synt_G - Mitochondrial ATP synthase g subunit
PFAM: PF04718 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 100 (92)
Sequences: 646 (420)
Seq/√Len: 43.8
META: 0.211

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
90_I93_R3.4401.00
78_G81_V3.0401.00
72_A76_L2.8211.00
82_L86_F2.7911.00
61_G64_K2.4201.00
38_F41_A2.4051.00
90_I96_L2.3541.00
15_K18_L2.3011.00
18_L25_A2.2851.00
95_S100_K2.1851.00
12_Y16_V1.9900.99
79_A83_G1.9800.99
19_E22_K1.8900.99
75_G78_G1.8770.99
11_V15_K1.8340.99
78_G82_L1.7080.98
68_V71_A1.7080.98
87_V96_L1.6930.98
66_L96_L1.6900.97
89_E98_G1.6560.97
15_K19_E1.4910.95
86_F90_I1.4660.94
23_Q26_K1.4360.94
62_R65_N1.4040.93
67_T71_A1.3750.92
67_T70_E1.2990.90
47_K51_A1.2920.89
54_T61_G1.2340.87
14_S18_L1.2330.87
92_G99_Y1.2260.87
36_A39_P1.2100.86
37_E40_S1.1780.84
31_A85_F1.1640.84
43_Q46_F1.1430.83
21_F25_A1.1090.81
12_Y15_K1.0950.80
70_E73_L1.0740.79
75_G83_G1.0730.78
5_S9_P1.0730.78
4_P28_E1.0390.76
49_R52_S1.0200.75
49_R53_P1.0190.75
44_Q48_L1.0110.74
34_T44_Q1.0070.74
4_P8_K1.0030.74
13_Y83_G0.9820.72
81_V84_W0.9810.72
30_L91_I0.9730.71
30_L81_V0.9480.69
18_L22_K0.9420.69
50_L53_P0.9120.66
77_V80_E0.9060.66
37_E78_G0.9060.66
48_L53_P0.8940.65
65_N68_V0.8830.64
16_V24_Y0.8600.62
7_V10_A0.8580.61
42_Y46_F0.8490.61
31_A37_E0.8470.60
15_K21_F0.8330.59
16_V22_K0.8310.59
31_A39_P0.8310.59
24_Y38_F0.8170.58
21_F24_Y0.8100.57
18_L24_Y0.8000.56
80_E84_W0.7970.56
4_P7_V0.7890.55
10_A64_K0.7810.54
93_R98_G0.7800.54
83_G93_R0.7790.54
41_A45_L0.7740.54
6_L10_A0.7630.53
94_R100_K0.7600.52
8_K13_Y0.7470.51
46_F50_L0.7450.51
14_S22_K0.7440.51
77_V81_V0.7430.51
25_A30_L0.7390.50
9_P13_Y0.7390.50
51_A61_G0.7390.50
66_L80_E0.7200.48
26_K76_L0.7200.48
83_G90_I0.7150.48
40_S44_Q0.7140.48
43_Q85_F0.7080.47
10_A13_Y0.7060.47
28_E32_P0.7000.46
9_P12_Y0.6970.46
12_Y19_E0.6950.46
50_L54_T0.6950.46
77_V93_R0.6940.46
45_L96_L0.6900.46
93_R99_Y0.6890.45
52_S60_L0.6800.45
31_A96_L0.6790.44
16_V20_L0.6780.44
88_G99_Y0.6670.43
24_Y90_I0.6490.42
43_Q78_G0.6410.41
5_S8_K0.6400.41
75_G79_A0.6380.41
34_T37_E0.6310.40
36_A64_K0.6270.40
5_S64_K0.6260.40
34_T45_L0.6180.39
5_S96_L0.6140.38
67_T86_F0.6110.38
44_Q47_K0.6030.37
83_G86_F0.5990.37
84_W87_V0.5970.37
72_A90_I0.5920.36
71_A74_N0.5840.36
38_F93_R0.5830.36
42_Y87_V0.5800.35
13_Y79_A0.5790.35
64_K91_I0.5720.35
90_I94_R0.5710.35
35_P70_E0.5700.35
72_A100_K0.5690.34
33_P85_F0.5610.34
71_A76_L0.5540.33
13_Y17_R0.5530.33
73_L77_V0.5520.33
3_V7_V0.5480.33
25_A32_P0.5440.32
17_R20_L0.5430.32
39_P68_V0.5430.32
49_R97_V0.5280.31
65_N79_A0.5260.31
88_G98_G0.5210.30
81_V90_I0.5180.30
38_F49_R0.5150.30
91_I99_Y0.5110.30
13_Y28_E0.5080.29
7_V87_V0.5040.29
9_P79_A0.5040.29
86_F91_I0.5020.29
17_R72_A0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2c1wA 1 0.79 10.7 0.917 Contact Map
3v76A 2 0.98 7 0.924 Contact Map
2w9yA 1 0.65 5.4 0.928 Contact Map
1xcrA 1 0.72 5.1 0.929 Contact Map
1seiA 2 0.63 5 0.929 Contact Map
3bbnH 1 0.65 3.9 0.933 Contact Map
4rb5H 1 0.65 2.9 0.937 Contact Map
3rf2A 1 0.65 2.8 0.937 Contact Map
4bzjA 2 0 2.8 0.937 Contact Map
4pdbA 1 0.64 2.6 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0057 seconds.