FUSC - PFAM28P - GREMLIN Contacts

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FUSC - Fusaric acid resistance protein family

PFAM:	PF04632	Sequences: DWLFALKTFLAAMLALYIAFWLGLPRPYWAMTTVFIVSQPLSGAVLSKALYRLLGTLVGAAAAVLLVALFVQAPELFLLALALWVGLCLYLSLLLRNFRSYAFVLAGYTAAIIALPAVDDPEGVFDIAVARVSEILLGIVCATLVSALLFPRSARPALRARLAARLADAARLAADALAGEPAAAAREAARRRLAADIVALEALRSHAAFESSRLRRRSRALRALLARLLALLPLLSALADRLAALRAAGAALAAELAALLAELAAWDAAAAAAALAAALAALRARLRALRPALAADTPWARLLLARLAERLAELVDALADLAALRAAIAAPRRRVRLPLHRDNGLALRNALRAALAILLACLFWIATGWPGGATAVLLAAVVCSLFATLDNPAPAARLFLIGTLLAAVLAALYLFFVLPQLDGFPLLALVLAPVLLLAGLLMARPRTAGIGLGLAVFFALLLAPQNPMTYDFASFLNSALAILLGVLVAALVFRLLRPVSPAWRARRLLRALRRDLARLARGPLPRDRARFESRMLDRLAQLAPRLAAAPPAQRAALRDALAALRVGLAIIRLRRLLARLLPPALRAALDAVLAALAFRAPLAARRGRALAALAALLAALDAALAALAADPAAAALRRALAALVGLRRALFPDASPF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	657 (646)
Sequences:	3185 (2335)
Seq/√Len:	91.9
META:	0.516

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
53_L	136_L	5.199	1.00
90_Y	343_N	4.779	1.00
18_I	137_L	4.061	1.00
86_G	354_A	4.005	1.00
433_P	437_L	3.939	1.00
66_L	80_A	3.594	1.00
17_Y	424_F	3.588	1.00
86_G	350_A	3.564	1.00
356_A	379_A	3.536	1.00
14_L	141_C	3.512	1.00
411_A	475_F	3.451	1.00
621_D	624_L	3.421	1.00
9_F	13_M	3.420	1.00
60_A	132_V	3.139	1.00
421_L	430_V	2.953	1.00
410_A	475_F	2.943	1.00
617_L	621_D	2.872	1.00
363_F	367_T	2.800	1.00
84_W	88_C	2.784	1.00
101_Y	105_L	2.767	1.00
409_L	454_L	2.751	1.00
82_A	358_L	2.681	1.00
279_L	283_R	2.583	1.00
515_D	538_R	2.570	1.00
424_F	428_A	2.558	1.00
78_L	361_C	2.534	1.00
14_L	145_V	2.515	1.00
260_L	263_L	2.483	1.00
90_Y	350_A	2.470	1.00
257_A	261_A	2.464	1.00
260_L	264_A	2.455	1.00
52_R	56_T	2.452	1.00
407_A	479_A	2.395	1.00
390_D	393_A	2.371	1.00
19_A	27_P	2.355	1.00
515_D	534_R	2.320	1.00
262_E	285_R	2.296	1.00
360_A	488_V	2.295	1.00
13_M	428_A	2.286	1.00
18_I	141_C	2.275	1.00
117_A	127_I	2.273	1.00
81_L	110_A	2.269	1.00
52_R	101_Y	2.267	1.00
586_R	590_D	2.247	1.00
551_P	555_A	2.244	1.00
5_A	9_F	2.223	1.00
404_L	408_V	2.168	1.00
298_P	301_R	2.155	1.00
278_A	283_R	2.108	1.00
4_F	442_M	2.091	1.00
64_V	128_A	2.075	1.00
554_R	557_L	2.070	1.00
417_V	421_L	2.047	1.00
647_R	651_F	2.021	1.00
12_A	31_M	2.013	1.00
289_L	293_L	2.001	1.00
593_L	597_A	1.994	1.00
272_A	275_L	1.994	1.00
107_G	111_A	1.977	1.00
282_L	289_L	1.968	1.00
617_L	624_L	1.946	1.00
275_L	278_A	1.939	1.00
306_R	310_R	1.937	1.00
275_L	279_L	1.936	1.00
120_D	123_G	1.919	1.00
61_A	65_L	1.900	1.00
48_K	52_R	1.883	1.00
52_R	55_G	1.870	1.00
399_F	453_G	1.868	1.00
361_C	376_V	1.861	1.00
173_A	177_L	1.859	1.00
283_R	287_R	1.833	1.00
472_F	476_L	1.819	1.00
33_T	135_I	1.819	1.00
308_A	314_L	1.815	1.00
10_L	149_L	1.806	1.00
5_A	35_F	1.803	1.00
388_T	392_P	1.799	1.00
93_L	349_N	1.792	1.00
274_A	277_A	1.791	1.00
355_L	496_L	1.784	1.00
581_L	585_L	1.779	1.00
55_G	59_G	1.760	1.00
84_W	106_A	1.756	1.00
347_L	351_L	1.756	1.00
56_T	101_Y	1.752	1.00
412_L	416_F	1.752	1.00
271_A	275_L	1.744	1.00
95_L	103_F	1.737	1.00
56_T	131_R	1.735	1.00
63_A	110_A	1.733	1.00
423_G	426_L	1.726	1.00
48_K	131_R	1.725	1.00
564_L	567_G	1.696	1.00
70_F	80_A	1.696	1.00
25_P	130_A	1.696	1.00
617_L	623_A	1.693	1.00
43_G	48_K	1.664	1.00
587_A	591_A	1.658	1.00
388_T	393_A	1.653	1.00
389_L	392_P	1.651	1.00
385_L	390_D	1.649	1.00
256_L	260_L	1.644	1.00
417_V	430_V	1.644	1.00
360_A	379_A	1.644	1.00
369_W	372_G	1.631	1.00
90_Y	93_L	1.629	1.00
33_T	52_R	1.610	1.00
602_L	605_R	1.601	1.00
620_L	624_L	1.599	1.00
26_R	29_W	1.596	1.00
444_R	447_T	1.595	1.00
432_A	436_L	1.593	1.00
589_L	593_L	1.589	1.00
415_F	475_F	1.588	1.00
400_L	487_L	1.586	1.00
621_D	647_R	1.582	1.00
129_V	133_S	1.571	1.00
113_I	128_A	1.555	1.00
282_L	286_L	1.554	1.00
407_A	483_L	1.549	1.00
602_L	606_R	1.544	1.00
616_L	620_L	1.543	1.00
352_R	492_V	1.539	1.00
19_A	137_L	1.536	1.00
613_L	627_L	1.534	1.00
278_A	293_L	1.530	1.00
279_L	293_L	1.529	1.00
400_L	486_V	1.524	1.00
15_A	30_A	1.508	1.00
574_R	577_L	1.508	1.00
629_A	632_A	1.505	1.00
35_F	439_G	1.496	1.00
421_L	426_L	1.492	1.00
389_L	393_A	1.486	1.00
282_L	293_L	1.482	1.00
624_L	628_A	1.479	1.00
435_L	439_G	1.476	1.00
271_A	279_L	1.474	1.00
62_A	66_L	1.471	1.00
43_G	55_G	1.464	1.00
108_Y	385_L	1.464	1.00
360_A	375_A	1.463	1.00
232_L	235_L	1.462	1.00
130_A	133_S	1.458	1.00
227_R	235_L	1.456	1.00
272_A	286_L	1.456	1.00
101_Y	108_Y	1.454	1.00
12_A	35_F	1.451	1.00
588_A	593_L	1.444	0.99
48_K	56_T	1.443	0.99
43_G	52_R	1.438	0.99
616_L	621_D	1.436	0.99
359_L	492_V	1.434	0.99
627_L	630_D	1.423	0.99
49_A	143_T	1.419	0.99
613_L	621_D	1.405	0.99
274_A	279_L	1.401	0.99
48_K	55_G	1.401	0.99
561_L	564_L	1.398	0.99
105_L	108_Y	1.397	0.99
101_Y	131_R	1.393	0.99
616_L	622_A	1.386	0.99
310_R	315_V	1.385	0.99
75_E	79_L	1.380	0.99
616_L	628_A	1.380	0.99
62_A	84_W	1.363	0.99
592_V	595_A	1.363	0.99
350_A	354_A	1.363	0.99
20_F	466_N	1.361	0.99
399_F	402_G	1.361	0.99
102_A	140_V	1.360	0.99
627_L	631_P	1.357	0.99
409_L	458_F	1.351	0.99
386_F	390_D	1.344	0.99
605_R	609_A	1.342	0.99
342_D	507_R	1.336	0.99
551_P	554_R	1.334	0.99
48_K	101_Y	1.334	0.99
579_R	591_A	1.321	0.99
101_Y	107_G	1.320	0.99
591_A	595_A	1.318	0.99
590_D	594_A	1.312	0.99
125_F	129_V	1.310	0.99
303_L	310_R	1.304	0.99
362_L	366_A	1.300	0.99
82_A	357_I	1.299	0.99
605_R	608_R	1.296	0.99
137_L	141_C	1.287	0.99
631_P	634_A	1.286	0.99
619_A	622_A	1.277	0.99
116_P	119_D	1.277	0.99
364_W	372_G	1.276	0.99
7_K	150_F	1.276	0.99
529_A	534_R	1.272	0.99
359_L	488_V	1.272	0.99
628_A	631_P	1.270	0.99
592_V	597_A	1.268	0.99
279_L	286_L	1.267	0.99
613_L	617_L	1.264	0.99
160_A	164_A	1.259	0.99
275_L	283_R	1.257	0.99
582_P	585_L	1.257	0.99
382_V	489_A	1.254	0.99
559_D	564_L	1.247	0.98
54_L	102_A	1.247	0.98
62_A	65_L	1.244	0.98
16_L	20_F	1.240	0.98
438_A	455_A	1.239	0.98
8_T	38_S	1.238	0.98
592_V	596_L	1.236	0.98
304_L	308_A	1.234	0.98
10_L	145_V	1.231	0.98
616_L	623_A	1.227	0.98
49_A	59_G	1.226	0.98
310_R	313_E	1.222	0.98
303_L	311_L	1.222	0.98
299_W	303_L	1.219	0.98
395_A	399_F	1.217	0.98
622_A	626_A	1.213	0.98
107_G	112_I	1.212	0.98
29_W	131_R	1.211	0.98
8_T	34_V	1.211	0.98
613_L	624_L	1.211	0.98
101_Y	114_A	1.209	0.98
59_G	63_A	1.207	0.98
553_Q	556_A	1.205	0.98
270_A	276_A	1.205	0.98
271_A	293_L	1.203	0.98
621_D	625_A	1.201	0.98
535_M	538_R	1.196	0.98
278_A	281_A	1.195	0.98
291_P	294_A	1.195	0.98
438_A	454_L	1.193	0.98
279_L	290_R	1.191	0.98
272_A	290_R	1.188	0.98
40_P	45_V	1.187	0.98
272_A	277_A	1.186	0.98
161_R	165_R	1.183	0.98
6_L	10_L	1.180	0.98
17_Y	21_W	1.178	0.98
601_P	604_A	1.172	0.98
278_A	286_L	1.169	0.98
5_A	8_T	1.167	0.98
9_F	432_A	1.165	0.98
451_G	455_A	1.162	0.98
378_L	382_V	1.161	0.98
621_D	627_L	1.159	0.98
63_A	113_I	1.158	0.98
274_A	281_A	1.158	0.98
613_L	616_L	1.146	0.97
278_A	282_L	1.144	0.97
402_G	453_G	1.141	0.97
348_R	497_R	1.140	0.97
204_R	207_A	1.139	0.97
630_D	635_A	1.139	0.97
285_R	289_L	1.139	0.97
271_A	274_A	1.138	0.97
612_A	616_L	1.130	0.97
386_F	396_A	1.129	0.97
393_A	494_R	1.127	0.97
531_F	567_G	1.124	0.97
358_L	362_L	1.122	0.97
126_D	130_A	1.122	0.97
30_A	34_V	1.120	0.97
280_A	283_R	1.119	0.97
567_G	571_I	1.117	0.97
413_Y	430_V	1.115	0.97
162_L	224_L	1.115	0.97
270_A	275_L	1.114	0.97
47_S	206_H	1.112	0.97
284_A	289_L	1.109	0.97
91_L	94_L	1.108	0.97
47_S	51_Y	1.104	0.97
403_T	457_F	1.104	0.97
299_W	302_L	1.104	0.97
56_T	59_G	1.103	0.97
585_L	589_L	1.102	0.97
614_A	618_A	1.101	0.97
601_P	605_R	1.101	0.97
613_L	620_L	1.098	0.97
43_G	131_R	1.094	0.97
315_V	321_L	1.094	0.97
307_L	320_D	1.093	0.96
593_L	596_L	1.092	0.96
200_L	228_L	1.090	0.96
271_A	289_L	1.089	0.96
584_A	587_A	1.084	0.96
19_A	29_W	1.083	0.96
409_L	417_V	1.080	0.96
355_L	492_V	1.080	0.96
640_L	644_V	1.078	0.96
114_A	118_V	1.077	0.96
315_V	327_A	1.076	0.96
613_L	628_A	1.076	0.96
282_L	288_A	1.076	0.96
87_L	91_L	1.074	0.96
603_A	606_R	1.072	0.96
268_A	290_R	1.072	0.96
283_R	286_L	1.071	0.96
559_D	562_A	1.071	0.96
37_V	139_I	1.067	0.96
100_S	105_L	1.064	0.96
304_L	307_L	1.063	0.96
262_E	265_A	1.058	0.96
261_A	265_A	1.057	0.96
29_W	101_Y	1.056	0.96
199_A	204_R	1.056	0.96
417_V	434_V	1.056	0.96
386_F	489_A	1.053	0.96
352_R	497_R	1.052	0.96
627_L	632_A	1.052	0.96
256_L	264_A	1.051	0.96
29_W	134_E	1.051	0.96
398_L	401_I	1.048	0.96
447_T	451_G	1.042	0.95
601_P	609_A	1.041	0.95
302_L	307_L	1.039	0.95
53_L	57_L	1.037	0.95
89_L	384_S	1.036	0.95
391_N	498_P	1.036	0.95
131_R	134_E	1.032	0.95
581_L	589_L	1.028	0.95
632_A	635_A	1.027	0.95
286_L	289_L	1.025	0.95
15_A	19_A	1.024	0.95
375_A	484_L	1.022	0.95
572_R	576_L	1.021	0.95
343_N	350_A	1.016	0.95
271_A	282_L	1.014	0.95
204_R	209_F	1.014	0.95
282_L	291_P	1.013	0.95
318_L	322_A	1.010	0.95
154_A	162_L	1.002	0.94
52_R	131_R	1.000	0.94
275_L	281_A	0.999	0.94
281_A	285_R	0.998	0.94
406_A	457_F	0.994	0.94
535_M	541_Q	0.993	0.94
56_T	109_T	0.992	0.94
111_A	380_A	0.986	0.94
84_W	108_Y	0.983	0.94
42_S	45_V	0.983	0.94
616_L	624_L	0.981	0.94
276_A	284_A	0.977	0.94
29_W	381_V	0.975	0.93
52_R	59_G	0.974	0.93
48_K	59_G	0.974	0.93
314_L	317_A	0.974	0.93
57_L	61_A	0.973	0.93
299_W	306_R	0.969	0.93
553_Q	576_L	0.966	0.93
218_S	222_R	0.965	0.93
29_W	33_T	0.965	0.93
435_L	459_A	0.964	0.93
275_L	282_L	0.964	0.93
274_A	284_A	0.963	0.93
466_N	470_Y	0.963	0.93
488_V	492_V	0.960	0.93
604_A	609_A	0.960	0.93
588_A	591_A	0.959	0.93
33_T	48_K	0.956	0.93
95_L	99_R	0.954	0.93
259_L	262_E	0.954	0.93
627_L	633_A	0.954	0.93
585_L	594_A	0.953	0.93
56_T	135_I	0.952	0.93
20_F	27_P	0.952	0.93
19_A	30_A	0.950	0.93
83_L	87_L	0.950	0.93
615_A	629_A	0.947	0.92
108_Y	112_I	0.947	0.92
51_Y	99_R	0.947	0.92
279_L	289_L	0.945	0.92
278_A	289_L	0.945	0.92
622_A	627_L	0.944	0.92
58_V	106_A	0.935	0.92
111_A	115_L	0.934	0.92
378_L	381_V	0.930	0.92
622_A	630_D	0.928	0.92
457_F	460_L	0.927	0.92
33_T	109_T	0.926	0.92
306_R	309_E	0.926	0.92
43_G	56_T	0.925	0.92
237_A	241_R	0.924	0.91
301_R	305_A	0.923	0.91
277_A	283_R	0.920	0.91
107_G	110_A	0.917	0.91
270_A	279_L	0.916	0.91
611_A	615_A	0.915	0.91
629_A	634_A	0.915	0.91
104_V	384_S	0.914	0.91
418_L	421_L	0.911	0.91
298_P	305_A	0.907	0.91
382_V	456_V	0.907	0.91
9_F	35_F	0.906	0.91
268_A	283_R	0.905	0.91
615_A	619_A	0.903	0.91
310_R	314_L	0.903	0.91
615_A	632_A	0.903	0.91
5_A	439_G	0.900	0.90
286_L	290_R	0.898	0.90
43_G	101_Y	0.896	0.90
535_M	539_L	0.896	0.90
608_R	612_A	0.895	0.90
285_R	288_A	0.895	0.90
43_G	59_G	0.892	0.90
383_C	489_A	0.890	0.90
230_A	233_P	0.890	0.90
53_L	140_V	0.888	0.90
142_A	146_S	0.885	0.90
609_A	624_L	0.885	0.90
608_R	613_L	0.885	0.90
382_V	403_T	0.883	0.90
276_A	279_L	0.881	0.89
585_L	596_L	0.880	0.89
570_I	596_L	0.879	0.89
587_A	590_D	0.879	0.89
281_A	291_P	0.879	0.89
33_T	56_T	0.876	0.89
584_A	591_A	0.875	0.89
161_R	164_A	0.872	0.89
36_I	52_R	0.871	0.89
271_A	278_A	0.871	0.89
55_G	131_R	0.869	0.89
118_V	372_G	0.868	0.89
639_A	646_L	0.866	0.89
210_E	227_R	0.865	0.89
268_A	271_A	0.865	0.89
592_V	602_L	0.865	0.89
398_L	449_G	0.863	0.88
7_K	149_L	0.863	0.88
275_L	293_L	0.862	0.88
578_A	590_D	0.861	0.88
618_A	623_A	0.860	0.88
300_A	304_L	0.860	0.88
144_L	148_L	0.860	0.88
11_A	23_G	0.859	0.88
586_R	626_A	0.858	0.88
594_A	597_A	0.858	0.88
7_K	42_S	0.857	0.88
229_L	235_L	0.856	0.88
364_W	369_W	0.854	0.88
47_S	59_G	0.854	0.88
245_L	252_L	0.853	0.88
622_A	629_A	0.852	0.88
625_A	630_D	0.849	0.88
63_A	132_V	0.846	0.87
622_A	628_A	0.843	0.87
398_L	402_G	0.842	0.87
268_A	293_L	0.842	0.87
283_R	293_L	0.839	0.87
281_A	286_L	0.839	0.87
270_A	273_A	0.839	0.87
611_A	624_L	0.838	0.87
38_S	142_A	0.838	0.87
534_R	542_L	0.838	0.87
273_A	280_A	0.837	0.87
610_L	624_L	0.835	0.87
617_L	628_A	0.834	0.87
567_G	570_I	0.832	0.87
307_L	311_L	0.830	0.86
306_R	315_V	0.829	0.86
88_C	106_A	0.829	0.86
192_R	196_D	0.828	0.86
272_A	279_L	0.828	0.86
604_A	608_R	0.828	0.86
88_C	110_A	0.824	0.86
270_A	277_A	0.824	0.86
460_L	482_I	0.824	0.86
302_L	313_E	0.823	0.86
10_L	432_A	0.822	0.86
614_A	630_D	0.820	0.86
589_L	595_A	0.818	0.86
386_F	389_L	0.817	0.86
625_A	628_A	0.816	0.85
274_A	278_A	0.816	0.85
413_Y	434_V	0.815	0.85
621_D	629_A	0.815	0.85
550_P	553_Q	0.814	0.85
299_W	315_V	0.812	0.85
617_L	622_A	0.811	0.85
382_V	396_A	0.810	0.85
278_A	287_R	0.809	0.85
618_A	621_D	0.807	0.85
645_G	648_R	0.807	0.85
303_L	307_L	0.804	0.85
618_A	633_A	0.804	0.85
612_A	628_A	0.802	0.84
276_A	281_A	0.802	0.84
616_L	627_L	0.801	0.84
108_Y	111_A	0.801	0.84
299_W	307_L	0.800	0.84
101_Y	113_I	0.798	0.84
583_P	586_R	0.797	0.84
7_K	151_P	0.797	0.84
434_V	454_L	0.797	0.84
111_A	114_A	0.797	0.84
395_A	398_L	0.796	0.84
555_A	558_R	0.796	0.84
285_R	293_L	0.796	0.84
276_A	280_A	0.796	0.84
103_F	209_F	0.796	0.84
109_T	131_R	0.795	0.84
637_R	641_A	0.795	0.84
29_W	43_G	0.795	0.84
280_A	293_L	0.794	0.84
402_G	405_L	0.793	0.84
618_A	622_A	0.792	0.84
277_A	284_A	0.792	0.84
297_T	300_A	0.792	0.84
89_L	93_L	0.791	0.84
91_L	103_F	0.790	0.84
388_T	485_G	0.788	0.83
586_R	589_L	0.787	0.83
606_R	621_D	0.787	0.83
115_L	118_V	0.785	0.83
303_L	324_L	0.784	0.83
49_A	140_V	0.784	0.83
369_W	477_N	0.784	0.83
36_I	418_L	0.780	0.83
583_P	596_L	0.780	0.83
644_V	647_R	0.780	0.83
267_D	270_A	0.780	0.83
453_G	457_F	0.778	0.83
408_V	412_L	0.778	0.83
279_L	282_L	0.776	0.82
400_L	483_L	0.775	0.82
611_A	618_A	0.775	0.82
92_S	105_L	0.774	0.82
583_P	589_L	0.772	0.82
614_A	626_A	0.772	0.82
302_L	306_R	0.772	0.82
642_A	649_A	0.771	0.82
620_L	623_A	0.769	0.82
585_L	588_A	0.769	0.82
115_L	361_C	0.768	0.82
97_N	352_R	0.766	0.82
601_P	606_R	0.766	0.82
620_L	625_A	0.765	0.82
602_L	609_A	0.762	0.81
118_V	365_I	0.762	0.81
127_I	131_R	0.761	0.81
532_E	536_L	0.756	0.81
89_L	353_A	0.754	0.81
386_F	392_P	0.753	0.81
642_A	646_L	0.752	0.80
302_L	310_R	0.751	0.80
561_L	567_G	0.751	0.80
19_A	36_I	0.749	0.80
136_L	140_V	0.748	0.80
570_I	576_L	0.748	0.80
611_A	616_L	0.747	0.80
310_R	324_L	0.747	0.80
573_L	577_L	0.747	0.80
101_Y	109_T	0.746	0.80
417_V	431_L	0.745	0.80
36_I	108_Y	0.744	0.80
168_D	171_R	0.743	0.80
555_A	560_A	0.743	0.80
375_A	485_G	0.743	0.80
623_A	634_A	0.743	0.80
617_L	620_L	0.741	0.79
311_L	314_L	0.740	0.79
611_A	623_A	0.740	0.79
36_I	105_L	0.740	0.79
307_L	314_L	0.740	0.79
73_A	485_G	0.739	0.79
615_A	618_A	0.739	0.79
168_D	192_R	0.736	0.79
277_A	280_A	0.736	0.79
269_A	272_A	0.735	0.79
281_A	293_L	0.731	0.79
56_T	60_A	0.731	0.79
553_Q	558_R	0.730	0.78
584_A	594_A	0.729	0.78
304_L	311_L	0.727	0.78
574_R	590_D	0.725	0.78
101_Y	106_A	0.725	0.78
48_K	51_Y	0.723	0.78
171_R	175_D	0.723	0.78
555_A	563_A	0.722	0.78
131_R	138_G	0.722	0.78
34_V	38_S	0.722	0.78
645_G	649_A	0.721	0.78
64_V	124_V	0.721	0.78
600_A	608_R	0.721	0.78
434_V	458_F	0.719	0.77
29_W	55_G	0.718	0.77
227_R	233_P	0.717	0.77
618_A	628_A	0.715	0.77
534_R	538_R	0.714	0.77
169_A	172_L	0.714	0.77
36_I	456_V	0.713	0.77
296_D	299_W	0.713	0.77
282_L	294_A	0.712	0.77
384_S	387_A	0.712	0.77
620_L	626_A	0.712	0.77
610_L	617_L	0.710	0.77
122_E	126_D	0.709	0.76
628_A	632_A	0.708	0.76
14_L	431_L	0.707	0.76
66_L	77_F	0.706	0.76
615_A	622_A	0.705	0.76
217_R	220_A	0.705	0.76
282_L	285_R	0.704	0.76
43_G	47_S	0.703	0.76
630_D	634_A	0.703	0.76
588_A	597_A	0.700	0.76
613_L	626_A	0.700	0.76
308_A	315_V	0.700	0.76
320_D	329_A	0.700	0.76
51_Y	59_G	0.700	0.76
424_F	427_L	0.699	0.75
262_E	266_W	0.697	0.75
377_L	384_S	0.697	0.75
13_M	431_L	0.696	0.75
622_A	632_A	0.696	0.75
624_L	630_D	0.696	0.75
345_L	499_V	0.695	0.75
549_A	555_A	0.695	0.75
317_A	320_D	0.695	0.75
355_L	572_R	0.694	0.75
226_A	229_L	0.692	0.75
310_R	321_L	0.692	0.75
429_L	433_P	0.690	0.74
583_P	587_A	0.688	0.74
590_D	628_A	0.688	0.74
277_A	281_A	0.687	0.74
280_A	284_A	0.686	0.74
162_L	165_R	0.685	0.74
346_A	353_A	0.685	0.74
33_T	131_R	0.682	0.74
594_A	625_A	0.682	0.74
386_F	493_F	0.681	0.74
276_A	291_P	0.680	0.73
302_L	308_A	0.680	0.73
270_A	280_A	0.679	0.73
552_A	555_A	0.678	0.73
413_Y	417_V	0.676	0.73
297_T	312_A	0.676	0.73
82_A	354_A	0.675	0.73
645_G	651_F	0.674	0.73
611_A	632_A	0.674	0.73
298_P	307_L	0.673	0.73
34_V	42_S	0.672	0.73
611_A	621_D	0.672	0.73
11_A	34_V	0.671	0.72
585_L	595_A	0.670	0.72
223_A	227_R	0.668	0.72
105_L	112_I	0.667	0.72
108_Y	380_A	0.667	0.72
154_A	157_A	0.667	0.72
555_A	559_D	0.667	0.72
31_M	103_F	0.666	0.72
281_A	289_L	0.665	0.72
52_R	105_L	0.664	0.72
207_A	221_L	0.663	0.72
323_A	329_A	0.663	0.72
538_R	546_L	0.662	0.71
612_A	625_A	0.661	0.71
269_A	274_A	0.660	0.71
437_L	440_L	0.659	0.71
108_Y	116_P	0.658	0.71
610_L	623_A	0.658	0.71
155_R	210_E	0.657	0.71
533_S	537_D	0.656	0.71
8_T	12_A	0.656	0.71
15_A	141_C	0.656	0.71
110_A	113_I	0.654	0.70
648_R	651_F	0.654	0.70
5_A	29_W	0.653	0.70
600_A	603_A	0.653	0.70
606_R	609_A	0.651	0.70
302_L	305_A	0.651	0.70
584_A	634_A	0.650	0.70
152_R	158_L	0.649	0.70
571_I	576_L	0.649	0.70
435_L	458_F	0.648	0.70
260_L	265_A	0.648	0.70
272_A	282_L	0.646	0.70
602_L	607_G	0.646	0.70
569_A	576_L	0.646	0.70
319_A	324_L	0.645	0.69
570_I	593_L	0.644	0.69
27_P	43_G	0.643	0.69
579_R	582_P	0.640	0.69
356_A	380_A	0.639	0.69
406_A	461_L	0.639	0.69
643_L	646_L	0.639	0.69
268_A	272_A	0.638	0.69
644_V	648_R	0.638	0.69
274_A	292_A	0.637	0.68
89_L	92_S	0.635	0.68
583_P	594_A	0.635	0.68
363_F	484_L	0.634	0.68
574_R	594_A	0.634	0.68
594_A	612_A	0.633	0.68
621_D	631_P	0.633	0.68
542_L	560_A	0.633	0.68
609_A	613_L	0.632	0.68
306_R	311_L	0.631	0.68
539_L	547_A	0.629	0.68
475_F	479_A	0.628	0.67
155_R	159_R	0.628	0.67
174_A	178_A	0.628	0.67
134_E	142_A	0.628	0.67
302_L	318_L	0.627	0.67
549_A	560_A	0.627	0.67
29_W	48_K	0.626	0.67
165_R	228_L	0.625	0.67
297_T	305_A	0.625	0.67
352_R	505_A	0.625	0.67
256_L	306_R	0.625	0.67
325_R	329_A	0.624	0.67
304_L	312_A	0.623	0.67
424_F	466_N	0.623	0.67
16_L	22_L	0.623	0.67
3_L	7_K	0.622	0.67
398_L	450_I	0.622	0.67
604_A	613_L	0.622	0.67
399_F	403_T	0.619	0.66
315_V	322_A	0.619	0.66
256_L	263_L	0.619	0.66
35_F	74_P	0.619	0.66
49_A	55_G	0.618	0.66
135_I	568_L	0.618	0.66
211_S	214_L	0.617	0.66
343_N	346_A	0.616	0.66
27_P	108_Y	0.616	0.66
259_L	263_L	0.616	0.66
548_A	553_Q	0.616	0.66
369_W	375_A	0.616	0.66
528_R	532_E	0.615	0.66
625_A	629_A	0.615	0.66
272_A	283_R	0.614	0.66
298_P	302_L	0.613	0.66
611_A	627_L	0.613	0.66
303_L	317_A	0.613	0.66
386_F	393_A	0.612	0.65
541_Q	545_R	0.610	0.65
543_A	546_L	0.609	0.65
594_A	618_A	0.608	0.65
204_R	208_A	0.608	0.65
268_A	278_A	0.608	0.65
608_R	614_A	0.608	0.65
375_A	378_L	0.607	0.65
403_T	453_G	0.607	0.65
32_T	456_V	0.606	0.65
410_A	461_L	0.606	0.65
26_R	133_S	0.606	0.65
606_R	610_L	0.606	0.65
27_P	134_E	0.604	0.64
441_L	447_T	0.603	0.64
15_A	138_G	0.602	0.64
346_A	350_A	0.601	0.64
386_F	395_A	0.601	0.64
35_F	39_Q	0.601	0.64
83_L	354_A	0.599	0.64
614_A	624_L	0.598	0.64
588_A	594_A	0.598	0.64
62_A	80_A	0.597	0.64
77_F	114_A	0.596	0.63
247_A	252_L	0.596	0.63
277_A	282_L	0.595	0.63
622_A	634_A	0.594	0.63
429_L	496_L	0.594	0.63
639_A	644_V	0.594	0.63
600_A	615_A	0.594	0.63
287_R	291_P	0.593	0.63
601_P	607_G	0.593	0.63
271_A	276_A	0.591	0.63
594_A	605_R	0.591	0.63
224_L	227_R	0.590	0.63
582_P	587_A	0.590	0.63
60_A	128_A	0.590	0.63
235_L	238_L	0.589	0.62
86_G	91_L	0.589	0.62
445_P	448_A	0.589	0.62
537_D	541_Q	0.588	0.62
601_P	608_R	0.588	0.62
372_G	477_N	0.586	0.62
102_A	113_I	0.585	0.62
644_V	649_A	0.585	0.62
128_A	131_R	0.585	0.62
314_L	318_L	0.585	0.62
220_A	226_A	0.585	0.62
205_S	209_F	0.585	0.62
73_A	76_L	0.584	0.62
608_R	616_L	0.584	0.62
578_A	584_A	0.584	0.62
409_L	434_V	0.583	0.62
95_L	98_F	0.582	0.62
60_A	63_A	0.582	0.62
517_A	520_A	0.581	0.61
105_L	109_T	0.581	0.61
377_L	383_C	0.581	0.61
449_G	453_G	0.580	0.61
579_R	623_A	0.580	0.61
110_A	134_E	0.579	0.61
557_L	560_A	0.578	0.61
28_Y	138_G	0.577	0.61
642_A	647_R	0.577	0.61
46_L	147_A	0.577	0.61
380_A	384_S	0.576	0.61
68_A	72_Q	0.575	0.61
322_A	327_A	0.575	0.61
625_A	632_A	0.575	0.61
615_A	624_L	0.572	0.60
219_R	235_L	0.572	0.60
199_A	207_A	0.572	0.60
579_R	589_L	0.572	0.60
559_D	567_G	0.571	0.60
378_L	383_C	0.569	0.60
371_G	477_N	0.568	0.60
612_A	619_A	0.567	0.60
622_A	625_A	0.567	0.60
267_D	271_A	0.567	0.60
626_A	638_R	0.567	0.60
32_T	36_I	0.567	0.60
198_V	208_A	0.566	0.59
65_L	69_L	0.566	0.59
390_D	399_F	0.566	0.59
538_R	541_Q	0.565	0.59
630_D	633_A	0.565	0.59
387_A	392_P	0.565	0.59
567_G	574_R	0.565	0.59
197_I	200_L	0.564	0.59
625_A	631_P	0.563	0.59
304_L	314_L	0.563	0.59
621_D	626_A	0.562	0.59
544_P	547_A	0.562	0.59
291_P	295_A	0.561	0.59
281_A	327_A	0.560	0.59
55_G	101_Y	0.560	0.59
5_A	13_M	0.559	0.58
304_L	315_V	0.558	0.58
528_R	572_R	0.558	0.58
96_R	100_S	0.557	0.58
396_A	493_F	0.557	0.58
100_S	108_Y	0.557	0.58
619_A	628_A	0.556	0.58
8_T	439_G	0.556	0.58
36_I	139_I	0.556	0.58
568_L	575_R	0.556	0.58
646_L	650_L	0.555	0.58
76_L	121_P	0.555	0.58
123_G	126_D	0.555	0.58
457_F	482_I	0.554	0.58
619_A	633_A	0.554	0.58
559_D	563_A	0.553	0.58
568_L	571_I	0.553	0.58
53_L	139_I	0.553	0.58
256_L	259_L	0.552	0.58
277_A	288_A	0.551	0.57
358_L	596_L	0.551	0.57
559_D	571_I	0.551	0.57
588_A	595_A	0.550	0.57
322_A	325_R	0.550	0.57
134_E	364_W	0.550	0.57
303_L	318_L	0.549	0.57
275_L	286_L	0.549	0.57
224_L	230_A	0.548	0.57
583_P	609_A	0.547	0.57
163_A	167_A	0.547	0.57
634_A	638_R	0.547	0.57
421_L	425_P	0.547	0.57
615_A	626_A	0.547	0.57
604_A	615_A	0.546	0.57
339_L	346_A	0.545	0.57
249_G	252_L	0.545	0.57
434_V	438_A	0.545	0.57
638_R	641_A	0.544	0.56
27_P	33_T	0.543	0.56
436_L	439_G	0.543	0.56
282_L	292_A	0.543	0.56
588_A	619_A	0.542	0.56
607_G	633_A	0.542	0.56
609_A	612_A	0.541	0.56
173_A	178_A	0.541	0.56
214_L	221_L	0.540	0.56
37_V	142_A	0.540	0.56
160_A	282_L	0.540	0.56
581_L	584_A	0.539	0.56
640_L	643_L	0.537	0.55
605_R	610_L	0.535	0.55
295_A	298_P	0.535	0.55
299_W	321_L	0.534	0.55
306_R	320_D	0.533	0.55
539_L	546_L	0.533	0.55
604_A	611_A	0.532	0.55
231_L	236_S	0.532	0.55
641_A	651_F	0.532	0.55
84_W	107_G	0.532	0.55
201_E	204_R	0.532	0.55
290_R	293_L	0.531	0.55
318_L	321_L	0.530	0.55
259_L	265_A	0.529	0.54
314_L	320_D	0.529	0.54
31_M	459_A	0.529	0.54
98_F	352_R	0.528	0.54
579_R	597_A	0.528	0.54
372_G	392_P	0.527	0.54
641_A	647_R	0.527	0.54
284_A	287_R	0.526	0.54
243_A	247_A	0.526	0.54
605_R	611_A	0.526	0.54
287_R	292_A	0.526	0.54
579_R	583_P	0.524	0.54
586_R	596_L	0.524	0.54
98_F	108_Y	0.523	0.54
37_V	43_G	0.523	0.54
33_T	36_I	0.523	0.54
230_A	235_L	0.523	0.54
468_M	471_D	0.522	0.53
297_T	301_R	0.522	0.53
607_G	614_A	0.522	0.53
610_L	616_L	0.521	0.53
88_C	107_G	0.521	0.53
306_R	317_A	0.521	0.53
570_I	574_R	0.520	0.53
174_A	177_L	0.520	0.53
392_P	399_F	0.520	0.53
56_T	105_L	0.520	0.53
104_V	116_P	0.520	0.53
222_R	230_A	0.520	0.53
406_A	453_G	0.519	0.53
614_A	627_L	0.518	0.53
41_L	45_V	0.518	0.53
7_K	95_L	0.518	0.53
109_T	135_I	0.517	0.53
549_A	553_Q	0.517	0.53
425_P	428_A	0.517	0.53
100_S	104_V	0.517	0.53
386_F	452_L	0.517	0.53
93_L	96_R	0.516	0.53
89_L	97_N	0.516	0.53
606_R	613_L	0.515	0.52
405_L	454_L	0.515	0.52
112_I	399_F	0.515	0.52
321_L	327_A	0.514	0.52
451_G	454_L	0.514	0.52
114_A	119_D	0.513	0.52
612_A	624_L	0.513	0.52
179_G	186_R	0.512	0.52
377_L	381_V	0.512	0.52
306_R	328_I	0.512	0.52
641_A	644_V	0.512	0.52
532_E	535_M	0.512	0.52
47_S	55_G	0.511	0.52
86_G	90_Y	0.509	0.52
591_A	614_A	0.508	0.51
613_L	629_A	0.507	0.51
624_L	640_L	0.507	0.51
125_F	134_E	0.507	0.51
304_L	310_R	0.505	0.51
82_A	86_G	0.505	0.51
623_A	633_A	0.505	0.51
166_L	485_G	0.504	0.51
588_A	592_V	0.504	0.51
565_R	569_A	0.504	0.51
552_A	570_I	0.503	0.51
438_A	464_P	0.502	0.51
609_A	617_L	0.501	0.51
600_A	605_R	0.501	0.51
55_G	67_V	0.501	0.51
43_G	49_A	0.501	0.51
40_P	48_K	0.500	0.50
422_D	425_P	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4k0jA	3	0.2192	58.8	0.967	Contact Map
4dx5A	3	0.2314	47.2	0.969	Contact Map
3w9iA	3	0.2314	38.9	0.971	Contact Map
4mt1A	3	0.2116	32.2	0.972	Contact Map
3vouA	4	0.2009	29	0.972	Contact Map
3ne5A	3	0.2177	23.6	0.974	Contact Map
2ksfA	1	0.1507	23.4	0.974	Contact Map
3cn5A	3	0.2846	16.6	0.975	Contact Map
4eneA	2	0.2222	16.1	0.976	Contact Map
3nd0A	2	0.2237	15.6	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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