Ribophorin_I - PFAM28P - GREMLIN Contacts

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Ribophorin_I - Ribophorin I

PFAM:	PF04597	Sequences: FENTNVVRTIDLTSQYVKETTTITVENTGKSPVSEYYLAFPPDEADHLAYIEAKVKDGKDKEKGSEVELVLKVTELPVDAPSDTQYYSVTLPKPLAPGETVTLEVEYVLTHALKPLPAEITQSEKQLVLYTGSAYVLSPYPTKKQKTKVKLPSSNVESYTKLEKPVKSGSTITYGPYENVPPFSYSPITVHYENNKPFLTVTSLERDIEVSHWGNIAVEERYDLRHTGAKLKGPFSRVDYQRQQYYARPSNSGTSALKSLKTPLPAGAHDVYYRDEIGNISTSHLRPDSDRKEVELELRPRYPLFGGWKYSFTIGYNLPLSDFLRKDSGGKYVLKVPFLDPFEDVVVDELTVKVILPEGATNIKVSTPFPVDSQSDELHYTYLDTVGRPVVVLEKKNLVDEEHNQDFQVTYKFPKLAMLRKPLLVVAAFFLLFVAAIVY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	439 (426)
Sequences:	605 (462)
Seq/√Len:	22.4
META:	0.182

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
3_N	142_T	7.554	1.00
3_N	36_Y	7.052	1.00
271_V	285_L	5.845	1.00
36_Y	142_T	5.385	1.00
217_A	317_N	4.880	1.00
362_N	412_K	4.852	1.00
377_E	392_V	4.537	1.00
212_H	411_Y	4.425	1.00
215_N	317_N	4.337	1.00
119_E	230_K	4.280	1.00
270_D	317_N	4.263	1.00
208_I	352_V	3.441	1.00
111_H	348_D	3.056	1.00
209_E	215_N	2.954	0.99
413_F	421_K	2.921	0.99
338_F	369_F	2.867	0.99
203_S	349_E	2.844	0.99
324_L	334_L	2.745	0.99
200_T	227_T	2.718	0.99
279_N	283_S	2.664	0.99
365_V	391_V	2.661	0.99
273_Y	280_I	2.558	0.98
272_Y	315_G	2.544	0.98
201_V	204_L	2.514	0.98
379_H	390_V	2.499	0.98
39_A	86_Y	2.450	0.98
6_V	136_V	2.444	0.98
36_Y	103_L	2.430	0.98
3_N	6_V	2.338	0.97
226_H	399_V	2.308	0.97
363_I	389_P	2.222	0.96
210_V	334_L	2.203	0.96
352_V	407_F	2.186	0.96
335_K	406_D	2.169	0.96
48_L	109_L	2.161	0.95
38_L	53_A	2.145	0.95
134_A	188_I	2.130	0.95
240_Y	256_A	2.103	0.95
25_V	36_Y	2.073	0.94
384_D	388_R	2.070	0.94
6_V	23_I	2.035	0.94
121_T	124_E	1.977	0.93
199_L	257_L	1.956	0.92
226_H	305_F	1.952	0.92
91_L	103_L	1.951	0.92
349_E	394_E	1.932	0.92
53_A	89_V	1.884	0.91
280_I	310_Y	1.882	0.91
130_Y	224_L	1.865	0.90
195_N	226_H	1.857	0.90
354_V	407_F	1.780	0.88
226_H	304_L	1.777	0.88
421_K	424_L	1.765	0.88
358_E	387_G	1.761	0.88
198_F	228_G	1.748	0.87
414_P	417_A	1.743	0.87
113_L	192_Y	1.727	0.86
315_G	358_E	1.724	0.86
231_L	282_T	1.714	0.86
134_A	162_L	1.687	0.85
199_L	304_L	1.661	0.84
427_A	431_L	1.653	0.84
239_D	242_R	1.640	0.83
126_Q	229_A	1.630	0.83
372_D	407_F	1.619	0.83
127_L	157_E	1.614	0.82
110_T	346_V	1.599	0.82
395_K	403_H	1.594	0.82
111_H	200_T	1.579	0.81
38_L	89_V	1.570	0.81
205_E	351_T	1.554	0.80
134_A	298_L	1.532	0.79
356_L	409_V	1.520	0.78
96_A	99_E	1.519	0.78
385_T	424_L	1.508	0.78
165_P	177_Y	1.483	0.77
128_V	198_F	1.476	0.76
209_E	217_A	1.469	0.76
10_I	229_A	1.457	0.75
67_V	71_L	1.457	0.75
262_T	341_P	1.451	0.75
23_I	136_V	1.450	0.75
426_V	430_F	1.440	0.74
315_G	387_G	1.428	0.74
3_N	138_S	1.428	0.74
261_K	295_E	1.421	0.73
120_I	229_A	1.420	0.73
23_I	36_Y	1.417	0.73
388_R	433_F	1.390	0.72
290_D	293_E	1.385	0.71
114_K	131_T	1.369	0.70
335_K	408_Q	1.365	0.70
116_L	129_L	1.356	0.70
202_T	348_D	1.348	0.69
125_K	193_E	1.347	0.69
25_V	103_L	1.346	0.69
125_K	155_N	1.344	0.69
34_S	90_T	1.343	0.69
260_L	312_F	1.335	0.69
219_E	272_Y	1.333	0.68
268_A	318_L	1.331	0.68
216_I	323_F	1.324	0.68
296_L	391_V	1.315	0.67
391_V	409_V	1.313	0.67
27_N	97_P	1.308	0.67
128_V	194_N	1.307	0.67
153_S	398_L	1.305	0.67
49_A	74_T	1.295	0.66
369_F	403_H	1.291	0.66
135_Y	180_V	1.286	0.66
432_L	437_I	1.277	0.65
305_F	399_V	1.272	0.65
3_N	23_I	1.269	0.64
265_P	319_P	1.267	0.64
285_L	296_L	1.264	0.64
210_V	356_L	1.263	0.64
384_D	387_G	1.262	0.64
413_F	418_M	1.260	0.64
215_N	272_Y	1.250	0.63
278_G	301_R	1.247	0.63
111_H	346_V	1.236	0.62
123_S	239_D	1.235	0.62
273_Y	283_S	1.233	0.62
205_E	221_R	1.228	0.62
228_G	315_G	1.221	0.61
235_F	303_P	1.219	0.61
220_E	305_F	1.219	0.61
119_E	232_K	1.218	0.61
303_P	308_W	1.209	0.61
312_F	339_L	1.207	0.61
280_I	390_V	1.201	0.60
373_S	394_E	1.189	0.59
353_K	390_V	1.187	0.59
351_T	394_E	1.184	0.59
208_I	218_V	1.180	0.59
6_V	21_T	1.170	0.58
144_K	178_E	1.164	0.58
117_P	308_W	1.156	0.57
415_K	419_L	1.148	0.57
362_N	379_H	1.146	0.56
372_D	395_K	1.139	0.56
135_Y	145_Q	1.137	0.56
339_L	347_V	1.136	0.56
267_G	337_P	1.135	0.56
353_K	392_V	1.123	0.55
120_I	214_G	1.121	0.55
115_P	356_L	1.121	0.55
331_K	410_T	1.120	0.55
21_T	38_L	1.120	0.55
147_T	177_Y	1.116	0.54
203_S	223_D	1.113	0.54
200_T	346_V	1.107	0.54
164_K	167_K	1.102	0.53
209_E	281_S	1.097	0.53
309_K	314_I	1.093	0.53
6_V	10_I	1.092	0.53
275_D	301_R	1.092	0.53
236_S	409_V	1.092	0.53
384_D	421_K	1.079	0.52
418_M	421_K	1.077	0.52
352_V	393_L	1.068	0.51
114_K	180_V	1.066	0.51
275_D	278_G	1.065	0.51
203_S	351_T	1.065	0.51
233_G	368_P	1.063	0.51
23_I	39_A	1.059	0.51
129_L	189_T	1.053	0.50
2_E	143_K	1.051	0.50
347_V	350_L	1.051	0.50
12_L	296_L	1.047	0.50
216_I	320_L	1.046	0.50
361_T	412_K	1.046	0.50
44_E	47_H	1.046	0.50
17_V	113_L	1.046	0.50
382_Y	419_L	1.042	0.49
226_H	301_R	1.042	0.49
206_R	272_Y	1.041	0.49
119_E	394_E	1.035	0.49
301_R	357_P	1.028	0.48
27_N	32_P	1.024	0.48
211_S	384_D	1.023	0.48
39_A	139_P	1.017	0.48
89_V	350_L	1.017	0.48
17_V	99_E	1.014	0.47
191_H	274_R	1.014	0.47
35_E	60_D	1.009	0.47
110_T	348_D	1.008	0.47
213_W	422_P	1.006	0.47
51_I	391_V	1.005	0.47
431_L	435_A	1.004	0.47
134_A	186_S	1.004	0.47
220_E	298_L	0.999	0.46
3_N	25_V	0.992	0.46
310_Y	337_P	0.989	0.46
335_K	392_V	0.985	0.45
373_S	376_D	0.985	0.45
32_P	72_K	0.985	0.45
105_V	438_V	0.982	0.45
93_K	393_L	0.982	0.45
429_F	433_F	0.982	0.45
282_T	385_T	0.980	0.45
213_W	387_G	0.978	0.45
29_G	33_V	0.976	0.45
219_E	315_G	0.974	0.45
297_E	332_Y	0.974	0.45
321_S	335_K	0.972	0.45
271_V	348_D	0.971	0.44
214_G	229_A	0.968	0.44
198_F	304_L	0.967	0.44
11_D	236_S	0.967	0.44
294_V	310_Y	0.966	0.44
37_Y	86_Y	0.959	0.44
427_A	430_F	0.956	0.43
265_P	383_L	0.952	0.43
428_A	433_F	0.949	0.43
207_D	379_H	0.949	0.43
161_K	226_H	0.947	0.43
367_T	370_P	0.947	0.43
226_H	309_K	0.946	0.43
129_L	318_L	0.945	0.43
312_F	341_P	0.944	0.43
212_H	281_S	0.943	0.43
153_S	228_G	0.941	0.42
284_H	414_P	0.934	0.42
212_H	215_N	0.933	0.42
96_A	189_T	0.930	0.42
235_F	315_G	0.927	0.42
382_Y	398_L	0.927	0.42
296_L	314_I	0.923	0.41
315_G	384_D	0.918	0.41
216_I	262_T	0.915	0.41
299_R	316_Y	0.913	0.41
209_E	381_T	0.907	0.40
265_P	368_P	0.903	0.40
194_N	198_F	0.903	0.40
49_A	110_T	0.902	0.40
225_R	309_K	0.900	0.40
37_Y	88_S	0.897	0.40
106_E	222_Y	0.897	0.40
149_V	190_V	0.894	0.39
382_Y	387_G	0.891	0.39
217_A	320_L	0.890	0.39
164_K	177_Y	0.889	0.39
144_K	188_I	0.888	0.39
294_V	302_Y	0.884	0.39
25_V	91_L	0.883	0.39
269_H	317_N	0.882	0.39
71_L	75_E	0.882	0.39
312_F	343_E	0.879	0.38
27_N	95_L	0.878	0.38
151_L	172_I	0.878	0.38
170_S	181_P	0.877	0.38
71_L	349_E	0.877	0.38
8_R	147_T	0.876	0.38
99_E	144_K	0.874	0.38
122_Q	388_R	0.871	0.38
136_V	139_P	0.866	0.38
121_T	253_G	0.865	0.37
203_S	438_V	0.863	0.37
8_R	145_Q	0.862	0.37
358_E	382_Y	0.861	0.37
436_A	439_Y	0.859	0.37
229_A	399_V	0.858	0.37
96_A	438_V	0.858	0.37
130_Y	365_V	0.857	0.37
434_V	438_V	0.855	0.37
79_D	435_A	0.854	0.37
260_L	393_L	0.853	0.37
28_T	48_L	0.853	0.37
235_F	308_W	0.852	0.37
272_Y	358_E	0.852	0.37
135_Y	159_Y	0.848	0.36
374_Q	393_L	0.844	0.36
137_L	184_S	0.844	0.36
280_I	421_K	0.843	0.36
275_D	357_P	0.842	0.36
282_T	315_G	0.841	0.36
2_E	5_N	0.841	0.36
279_N	388_R	0.839	0.36
40_F	49_A	0.838	0.36
112_A	130_Y	0.837	0.36
109_L	220_E	0.834	0.36
47_H	180_V	0.827	0.35
360_A	363_I	0.819	0.35
198_F	226_H	0.818	0.35
158_S	191_H	0.818	0.35
117_P	300_P	0.815	0.34
54_K	57_D	0.812	0.34
211_S	315_G	0.812	0.34
122_Q	283_S	0.805	0.34
366_S	408_Q	0.805	0.34
34_S	184_S	0.801	0.33
223_D	309_K	0.801	0.33
403_H	407_F	0.799	0.33
129_L	377_E	0.797	0.33
172_I	273_Y	0.795	0.33
48_L	107_Y	0.795	0.33
105_V	439_Y	0.792	0.33
143_K	178_E	0.792	0.33
59_K	192_Y	0.791	0.33
229_A	274_R	0.791	0.33
214_G	324_L	0.790	0.33
87_Y	238_V	0.788	0.33
87_Y	367_T	0.788	0.33
149_V	178_E	0.788	0.33
56_K	92_P	0.781	0.32
391_V	425_V	0.780	0.32
268_A	418_M	0.780	0.32
206_R	313_T	0.780	0.32
206_R	213_W	0.779	0.32
317_N	320_L	0.777	0.32
406_D	417_A	0.776	0.32
233_G	389_P	0.775	0.32
195_N	253_G	0.775	0.32
56_K	60_D	0.774	0.32
6_V	382_Y	0.773	0.32
105_V	139_P	0.772	0.32
95_L	344_D	0.771	0.32
14_S	280_I	0.771	0.32
221_R	314_I	0.769	0.32
272_Y	422_P	0.769	0.32
271_V	299_R	0.767	0.31
202_T	309_K	0.762	0.31
83_D	230_K	0.761	0.31
312_F	337_P	0.760	0.31
149_V	188_I	0.760	0.31
214_G	407_F	0.759	0.31
122_Q	286_R	0.759	0.31
172_I	361_T	0.758	0.31
142_T	180_V	0.757	0.31
130_Y	174_Y	0.757	0.31
132_G	404_N	0.757	0.31
83_D	149_V	0.755	0.31
224_L	409_V	0.755	0.31
313_T	410_T	0.754	0.31
202_T	323_F	0.753	0.31
267_G	322_D	0.751	0.30
12_L	130_Y	0.751	0.30
175_G	315_G	0.750	0.30
258_K	431_L	0.750	0.30
126_Q	197_P	0.750	0.30
277_I	306_G	0.749	0.30
78_V	330_G	0.749	0.30
43_D	71_L	0.748	0.30
21_T	380_Y	0.747	0.30
215_N	381_T	0.747	0.30
216_I	336_V	0.746	0.30
238_V	258_K	0.744	0.30
183_F	202_T	0.740	0.30
27_N	305_F	0.737	0.30
101_V	182_P	0.737	0.30
7_V	22_T	0.736	0.30
146_K	168_S	0.735	0.30
93_K	429_F	0.735	0.30
12_L	196_K	0.734	0.30
277_I	338_F	0.731	0.29
185_Y	350_L	0.730	0.29
5_N	26_E	0.729	0.29
112_A	284_H	0.728	0.29
91_L	302_Y	0.725	0.29
124_E	348_D	0.723	0.29
256_A	380_Y	0.723	0.29
90_T	439_Y	0.723	0.29
66_E	71_L	0.723	0.29
118_A	154_S	0.720	0.29
66_E	69_L	0.720	0.29
286_R	297_E	0.720	0.29
271_V	431_L	0.720	0.29
268_A	316_Y	0.719	0.29
216_I	324_L	0.717	0.29
164_K	344_D	0.713	0.28
273_Y	386_V	0.712	0.28
198_F	421_K	0.712	0.28
196_K	302_Y	0.709	0.28
210_V	336_V	0.708	0.28
60_D	190_V	0.708	0.28
272_Y	387_G	0.708	0.28
182_P	290_D	0.707	0.28
131_T	189_T	0.705	0.28
332_Y	335_K	0.705	0.28
262_T	312_F	0.705	0.28
308_W	357_P	0.702	0.28
8_R	41_P	0.702	0.28
10_I	354_V	0.702	0.28
21_T	107_Y	0.700	0.28
226_H	274_R	0.699	0.28
222_Y	260_L	0.699	0.28
381_T	385_T	0.698	0.27
224_L	260_L	0.697	0.27
285_L	294_V	0.696	0.27
316_Y	342_F	0.696	0.27
41_P	189_T	0.693	0.27
111_H	228_G	0.692	0.27
214_G	309_K	0.690	0.27
204_L	297_E	0.689	0.27
206_R	299_R	0.687	0.27
5_N	22_T	0.687	0.27
299_R	335_K	0.685	0.27
237_R	308_W	0.685	0.27
213_W	283_S	0.684	0.27
312_F	411_Y	0.682	0.27
117_P	126_Q	0.679	0.26
21_T	146_K	0.678	0.26
141_P	258_K	0.677	0.26
201_V	225_R	0.677	0.26
130_Y	309_K	0.676	0.26
25_V	138_S	0.676	0.26
121_T	431_L	0.675	0.26
4_T	26_E	0.675	0.26
102_T	109_L	0.674	0.26
71_L	74_T	0.674	0.26
150_K	224_L	0.673	0.26
43_D	224_L	0.673	0.26
6_V	407_F	0.671	0.26
23_I	409_V	0.670	0.26
365_V	374_Q	0.670	0.26
134_A	277_I	0.666	0.26
211_S	236_S	0.666	0.26
237_R	384_D	0.664	0.26
128_V	229_A	0.663	0.26
302_Y	398_L	0.662	0.26
38_L	51_I	0.662	0.26
281_S	315_G	0.660	0.25
198_F	373_S	0.658	0.25
262_T	335_K	0.656	0.25
115_P	231_L	0.656	0.25
218_V	316_Y	0.656	0.25
20_T	99_E	0.655	0.25
202_T	225_R	0.654	0.25
281_S	300_P	0.651	0.25
84_T	137_L	0.650	0.25
423_L	434_V	0.649	0.25
11_D	415_K	0.649	0.25
117_P	306_G	0.645	0.25
284_H	360_A	0.642	0.25
16_Y	27_N	0.641	0.24
174_Y	188_I	0.640	0.24
316_Y	421_K	0.640	0.24
20_T	51_I	0.639	0.24
242_R	260_L	0.637	0.24
130_Y	180_V	0.637	0.24
226_H	275_D	0.637	0.24
369_F	395_K	0.636	0.24
211_S	387_G	0.635	0.24
226_H	278_G	0.634	0.24
45_A	87_Y	0.633	0.24
351_T	392_V	0.632	0.24
84_T	302_Y	0.632	0.24
14_S	17_V	0.632	0.24
220_E	404_N	0.631	0.24
24_T	330_G	0.630	0.24
206_R	370_P	0.630	0.24
72_K	75_E	0.627	0.24
25_V	426_V	0.627	0.24
25_V	35_E	0.627	0.24
152_P	266_A	0.626	0.24
107_Y	148_K	0.626	0.24
217_A	381_T	0.625	0.24
133_S	188_I	0.624	0.24
89_V	205_E	0.624	0.24
73_V	96_A	0.624	0.24
117_P	356_L	0.623	0.24
265_P	316_Y	0.623	0.24
148_K	173_T	0.622	0.24
317_N	381_T	0.622	0.24
169_G	344_D	0.621	0.23
239_D	355_I	0.619	0.23
117_P	229_A	0.618	0.23
42_P	46_D	0.618	0.23
95_L	351_T	0.617	0.23
156_V	172_I	0.616	0.23
37_Y	208_I	0.615	0.23
127_L	155_N	0.615	0.23
130_Y	187_P	0.613	0.23
331_K	409_V	0.612	0.23
145_Q	159_Y	0.612	0.23
179_N	241_Q	0.611	0.23
43_D	416_L	0.611	0.23
8_R	18_K	0.610	0.23
418_M	439_Y	0.610	0.23
209_E	214_G	0.610	0.23
376_D	430_F	0.607	0.23
229_A	397_N	0.606	0.23
355_I	379_H	0.605	0.23
148_K	171_T	0.605	0.23
311_S	320_L	0.604	0.23
190_V	361_T	0.604	0.23
173_T	254_T	0.602	0.23
152_P	192_Y	0.600	0.22
274_R	316_Y	0.599	0.22
209_E	212_H	0.598	0.22
383_L	389_P	0.598	0.22
6_V	32_P	0.596	0.22
310_Y	340_D	0.595	0.22
322_D	337_P	0.595	0.22
302_Y	310_Y	0.595	0.22
283_S	315_G	0.593	0.22
364_K	378_L	0.592	0.22
70_V	74_T	0.591	0.22
204_L	350_L	0.590	0.22
84_T	201_V	0.590	0.22
200_T	348_D	0.589	0.22
35_E	327_D	0.588	0.22
432_L	438_V	0.588	0.22
25_V	56_K	0.587	0.22
124_E	399_V	0.587	0.22
220_E	399_V	0.586	0.22
40_F	92_P	0.585	0.22
342_F	439_Y	0.583	0.22
312_F	345_V	0.583	0.22
113_L	177_Y	0.582	0.22
102_T	169_G	0.582	0.22
302_Y	380_Y	0.580	0.22
220_E	337_P	0.580	0.22
282_T	310_Y	0.580	0.22
9_T	69_L	0.580	0.22
371_V	398_L	0.579	0.21
236_S	241_Q	0.579	0.21
272_Y	305_F	0.579	0.21
87_Y	184_S	0.578	0.21
262_T	310_Y	0.578	0.21
205_E	349_E	0.577	0.21
216_I	311_S	0.576	0.21
216_I	379_H	0.576	0.21
5_N	144_K	0.576	0.21
134_A	386_V	0.575	0.21
16_Y	53_A	0.574	0.21
374_Q	434_V	0.574	0.21
422_P	433_F	0.572	0.21
98_G	138_S	0.571	0.21
282_T	358_E	0.571	0.21
82_S	360_A	0.570	0.21
192_Y	197_P	0.567	0.21
98_G	190_V	0.567	0.21
129_L	204_L	0.566	0.21
165_P	182_P	0.566	0.21
59_K	414_P	0.566	0.21
23_I	142_T	0.566	0.21
155_N	259_S	0.565	0.21
231_L	382_Y	0.563	0.21
191_H	316_Y	0.563	0.21
310_Y	421_K	0.560	0.21
339_L	398_L	0.558	0.21
89_V	376_D	0.557	0.20
179_N	370_P	0.555	0.20
220_E	397_N	0.555	0.20
31_S	124_E	0.554	0.20
162_L	184_S	0.551	0.20
134_A	160_T	0.550	0.20
21_T	56_K	0.550	0.20
81_P	103_L	0.549	0.20
122_Q	279_N	0.549	0.20
127_L	191_H	0.548	0.20
126_Q	306_G	0.548	0.20
338_F	395_K	0.548	0.20
272_Y	281_S	0.547	0.20
195_N	304_L	0.545	0.20
298_L	430_F	0.545	0.20
211_S	272_Y	0.543	0.20
397_N	430_F	0.542	0.20
211_S	388_R	0.542	0.20
237_R	280_I	0.541	0.20
103_L	325_R	0.541	0.20
201_V	256_A	0.541	0.20
170_S	204_L	0.541	0.20
338_F	371_V	0.540	0.20
132_G	337_P	0.540	0.20
117_P	384_D	0.540	0.20
23_I	105_V	0.539	0.20
158_S	352_V	0.539	0.20
4_T	100_T	0.539	0.20
208_I	262_T	0.539	0.20
212_H	283_S	0.539	0.20
152_P	179_N	0.538	0.20
116_L	210_V	0.537	0.20
354_V	434_V	0.536	0.20
313_T	391_V	0.535	0.20
127_L	204_L	0.535	0.20
321_S	337_P	0.535	0.20
405_Q	414_P	0.534	0.19
185_Y	210_V	0.533	0.19
430_F	434_V	0.533	0.19
127_L	325_R	0.530	0.19
205_E	353_K	0.530	0.19
16_Y	400_D	0.530	0.19
23_I	50_Y	0.530	0.19
41_P	44_E	0.529	0.19
42_P	108_V	0.528	0.19
397_N	413_F	0.528	0.19
138_S	204_L	0.527	0.19
369_F	392_V	0.527	0.19
79_D	99_E	0.527	0.19
95_L	101_V	0.527	0.19
132_G	391_V	0.527	0.19
101_V	391_V	0.525	0.19
96_A	391_V	0.525	0.19
340_D	404_N	0.525	0.19
280_I	298_L	0.525	0.19
208_I	350_L	0.524	0.19
337_P	408_Q	0.524	0.19
312_F	408_Q	0.524	0.19
192_Y	332_Y	0.522	0.19
122_Q	307_G	0.522	0.19
204_L	239_D	0.521	0.19
114_K	415_K	0.521	0.19
140_Y	306_G	0.520	0.19
47_H	112_A	0.520	0.19
274_R	310_Y	0.520	0.19
46_D	78_V	0.519	0.19
222_Y	312_F	0.518	0.19
3_N	204_L	0.517	0.19
395_K	399_V	0.517	0.19
156_V	343_E	0.515	0.19
3_N	21_T	0.515	0.19
114_K	439_Y	0.514	0.19
218_V	268_A	0.514	0.19
212_H	279_N	0.514	0.19
332_Y	371_V	0.514	0.19
237_R	303_P	0.514	0.19
371_V	423_L	0.512	0.19
166_V	188_I	0.512	0.19
33_V	101_V	0.512	0.19
231_L	306_G	0.510	0.18
209_E	388_R	0.509	0.18
152_P	414_P	0.508	0.18
344_D	382_Y	0.508	0.18
250_S	284_H	0.508	0.18
97_P	220_E	0.508	0.18
358_E	384_D	0.507	0.18
273_Y	335_K	0.506	0.18
181_P	184_S	0.506	0.18
119_E	181_P	0.506	0.18
9_T	30_K	0.505	0.18
132_G	259_S	0.503	0.18
354_V	416_L	0.502	0.18
14_S	229_A	0.501	0.18
312_F	417_A	0.501	0.18
320_L	393_L	0.500	0.18
358_E	381_T	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1yewA	3	0.2984	24.8	0.974	Contact Map
4phzA	3	0.2984	19	0.976	Contact Map
2l9uA	2	0.0501	4.2	0.982	Contact Map
2m20A	2	0.0456	3.6	0.983	Contact Map
3hxlA	1	0.205	2.9	0.983	Contact Map
3lmlA	1	0.2346	2.7	0.984	Contact Map
2xl4A	1	0.1276	2.6	0.984	Contact Map
3pg7A	1	0.1595	2.6	0.984	Contact Map
1d8bA	1	0.1481	2.4	0.984	Contact Map
1wv9A	2	0.2005	2.1	0.985	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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