GREMLIN Database
PqiA - Paraquat-inducible protein A
PFAM: PF04403 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 156 (153)
Sequences: 13643 (8438)
Seq/√Len: 682.2
META: 0.832

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
45_W53_A3.1841.00
45_W50_W2.9671.00
25_T34_E2.8901.00
42_V46_E2.6821.00
35_D39_S2.4171.00
2_Q79_R2.4081.00
11_A68_L2.3111.00
7_L138_L2.2121.00
12_L72_L2.1561.00
43_E46_E2.1341.00
41_V57_F2.1211.00
70_A90_L2.1031.00
43_E47_S2.0821.00
70_A94_V2.0381.00
16_I20_L1.8961.00
57_F62_V1.8551.00
5_L75_L1.8171.00
27_S32_S1.8161.00
58_L63_V1.7711.00
125_P129_L1.7581.00
5_L79_R1.7041.00
17_P21_L1.6761.00
38_L61_I1.6751.00
25_T32_S1.6521.00
76_L80_R1.6341.00
14_L138_L1.6251.00
28_L31_R1.6161.00
14_L134_A1.5891.00
10_A138_L1.5841.00
82_R86_G1.5701.00
89_R93_L1.5361.00
58_L62_V1.5321.00
25_T126_G1.4901.00
88_T92_R1.4651.00
54_L58_L1.4581.00
8_L72_L1.4311.00
14_L131_A1.4281.00
73_Y86_G1.4171.00
12_L68_L1.4131.00
15_Y135_V1.4081.00
128_G131_A1.4011.00
4_T75_L1.3791.00
8_L68_L1.3461.00
3_R145_S1.3451.00
23_I128_G1.3351.00
67_K98_G1.3231.00
8_L12_L1.3031.00
105_V129_L1.2981.00
15_Y65_L1.2661.00
21_L127_P1.2591.00
51_P54_L1.2231.00
63_V101_S1.2171.00
38_L42_V1.2151.00
5_L76_L1.2031.00
75_L79_R1.1971.00
8_L71_L1.1961.00
150_L154_R1.1811.00
27_S124_E1.1691.00
35_D43_E1.1591.00
83_R86_G1.1541.00
84_P87_R1.1521.00
137_V141_L1.1401.00
15_Y68_L1.1261.00
73_Y77_S1.1221.00
42_V45_W1.1081.00
19_N61_I1.1051.00
67_K101_S1.1041.00
96_F99_R1.1001.00
27_S30_G1.0921.00
68_L72_L1.0701.00
149_R153_D1.0521.00
72_L76_L1.0501.00
127_P131_A1.0491.00
130_Y134_A1.0471.00
44_L56_V1.0401.00
76_L79_R1.0391.00
17_P131_A1.0381.00
73_Y90_L1.0331.00
12_L65_L1.0331.00
92_R96_F1.0281.00
36_T39_S1.0241.00
116_K122_T1.0231.00
8_L75_L1.0221.00
15_Y19_N1.0121.00
89_R92_R1.0101.00
134_A138_L0.9981.00
126_G131_A0.9961.00
135_V139_T0.9921.00
11_A138_L0.9911.00
55_L59_A0.9891.00
141_L145_S0.9871.00
4_T142_A0.9871.00
51_P55_L0.9761.00
93_L96_F0.9681.00
25_T124_E0.9641.00
117_L121_A0.9481.00
48_G51_P0.9361.00
21_L128_G0.9351.00
103_L136_V0.9331.00
111_L123_V0.9311.00
17_P20_L0.9271.00
147_D150_L0.9211.00
65_L69_L0.9151.00
19_N36_T0.9131.00
74_L151_I0.9121.00
63_V97_L0.9011.00
78_L146_F0.8941.00
74_L94_V0.8921.00
6_A10_A0.8911.00
14_L135_V0.8901.00
11_A142_A0.8851.00
150_L153_D0.8821.00
95_E98_G0.8821.00
16_I19_N0.8771.00
41_V53_A0.8731.00
10_A14_L0.8701.00
116_K119_G0.8651.00
26_L121_A0.8621.00
67_K143_A0.8531.00
4_T145_S0.8451.00
140_M144_A0.8421.00
141_L144_A0.8351.00
60_S106_F0.8301.00
57_F61_I0.8211.00
10_A13_I0.8061.00
54_L57_F0.7951.00
33_Q43_E0.7941.00
101_S104_D0.7931.00
102_M105_V0.7881.00
68_L135_V0.7861.00
45_W54_L0.7841.00
5_L72_L0.7801.00
13_I16_I0.7801.00
81_G154_R0.7731.00
55_L58_L0.7671.00
13_I17_P0.7591.00
142_A145_S0.7581.00
107_V136_V0.7421.00
86_G89_R0.7361.00
115_V121_A0.7361.00
73_Y82_R0.7361.00
4_T8_L0.7311.00
28_L121_A0.7301.00
8_L142_A0.7301.00
109_G113_A0.7251.00
67_K94_V0.7221.00
2_Q5_L0.7211.00
18_A131_A0.7181.00
77_S84_P0.7171.00
77_S82_R0.7141.00
26_L49_S0.7141.00
18_A22_P0.7051.00
50_W54_L0.7051.00
135_V138_L0.6981.00
45_W57_F0.6951.00
133_A137_V0.6921.00
28_L33_Q0.6911.00
83_R87_R0.6891.00
77_S87_R0.6791.00
98_G101_S0.6731.00
129_L133_A0.6721.00
69_L73_Y0.6681.00
24_M123_V0.6661.00
63_V67_K0.6641.00
78_L151_I0.6531.00
7_L141_L0.6511.00
31_R34_E0.6471.00
77_S81_G0.6411.00
5_L9_L0.6411.00
66_L70_A0.6411.00
94_V103_L0.6351.00
118_G122_T0.6341.00
50_W53_A0.6291.00
20_L38_L0.6281.00
7_L11_A0.6261.00
138_L141_L0.6211.00
111_L114_L0.6201.00
9_L13_I0.6191.00
67_K71_L0.6171.00
105_V116_K0.6161.00
37_I40_G0.6151.00
91_Y94_V0.6071.00
72_L75_L0.6061.00
82_R87_R0.6021.00
82_R85_R0.5981.00
67_K132_F0.5951.00
73_Y85_R0.5941.00
34_E124_E0.5921.00
24_M108_V0.5881.00
107_V110_I0.5871.00
27_S31_R0.5841.00
44_L111_L0.5831.00
80_R84_P0.5821.00
113_A117_L0.5771.00
115_V123_V0.5761.00
26_L109_G0.5741.00
85_R88_T0.5701.00
59_A101_S0.5691.00
139_T143_A0.5671.00
18_A132_F0.5651.00
24_M110_I0.5641.00
27_S122_T0.5591.00
124_E127_P0.5561.00
105_V108_V0.5541.00
79_R83_R0.5541.00
115_V119_G0.5541.00
45_W48_G0.5521.00
24_M102_M0.5511.00
56_V60_S0.5471.00
142_A147_D0.5471.00
99_R109_G0.5461.00
76_L82_R0.5451.00
69_L72_L0.5431.00
80_R83_R0.5431.00
11_A15_Y0.5381.00
103_L135_V0.5351.00
110_I113_A0.5341.00
140_M143_A0.5281.00
93_L97_L0.5241.00
119_G131_A0.5221.00
7_L142_A0.5190.99
67_K139_T0.5190.99
81_G84_P0.5180.99
63_V136_V0.5160.99
19_N22_P0.5090.99
12_L16_I0.5060.99
110_I116_K0.5060.99
99_R103_L0.5030.99
77_S85_R0.5020.99
14_L17_P0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2lzqA 1 0.0897 2 0.947 Contact Map
4ev6A 3 0.4103 1.7 0.949 Contact Map
2kygC 1 0.1346 1.6 0.95 Contact Map
3wu2M 2 0.2115 1.3 0.952 Contact Map
4j72A 2 0.6859 1.3 0.952 Contact Map
4xk8I 1 0.1859 1.2 0.953 Contact Map
4r0cA 3 0.3013 1.2 0.953 Contact Map
4i0uA 4 0.3974 1.1 0.955 Contact Map
2wscI 1 0.1923 1 0.956 Contact Map
2k1aA 1 0.2692 1 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0067 seconds.