GREMLIN Database
FliO - Flagellar biosynthesis protein, FliO
PFAM: PF04347 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 90 (85)
Sequences: 14917 (12106)
Seq/√Len: 1313.0
META: 0.876

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
43_R59_E3.8581.00
22_R39_E3.1671.00
21_L27_L2.6841.00
36_V49_V2.6671.00
32_R51_P2.4471.00
26_R34_R2.4101.00
43_R58_H2.4011.00
30_G33_E2.0431.00
48_G54_I1.9901.00
56_L59_E1.9791.00
39_E44_Q1.9551.00
26_R36_V1.8481.00
35_L38_V1.8421.00
84_L87_R1.8381.00
84_L88_A1.8381.00
45_L58_H1.7991.00
50_T53_G1.7611.00
39_E42_G1.7221.00
20_R25_A1.6651.00
49_V54_I1.6081.00
45_L56_L1.5541.00
24_L39_E1.5411.00
82_A86_K1.5231.00
33_E51_P1.5031.00
40_V46_L1.4921.00
37_L40_V1.4291.00
19_G25_A1.4201.00
38_V47_L1.3581.00
41_G44_Q1.3441.00
23_V27_L1.3191.00
24_L44_Q1.2971.00
35_L46_L1.2581.00
29_L36_V1.1631.00
43_R61_D1.1481.00
21_L37_L1.1441.00
1_W5_R1.0901.00
29_L35_L1.0661.00
40_V60_L1.0641.00
33_E50_T1.0551.00
35_L57_L1.0391.00
62_D65_E1.0051.00
34_R49_V0.9911.00
50_T54_I0.9851.00
44_Q60_L0.9791.00
42_G62_D0.9791.00
23_V36_V0.9571.00
62_D66_P0.9471.00
36_V47_L0.9211.00
32_R36_V0.8951.00
27_L35_L0.8801.00
11_R14_G0.8591.00
35_L54_I0.8551.00
26_R30_G0.8491.00
47_L54_I0.8341.00
66_P69_L0.8211.00
72_A75_P0.8171.00
80_S83_Q0.8021.00
23_V26_R0.7931.00
26_R33_E0.7831.00
21_L40_V0.7811.00
83_Q86_K0.7721.00
66_P70_A0.7721.00
33_E49_V0.7521.00
46_L58_H0.7481.00
20_R41_G0.7391.00
44_Q65_E0.7351.00
10_G13_G0.7331.00
63_P67_E0.7291.00
37_L60_L0.7131.00
45_L59_E0.7121.00
65_E69_L0.6821.00
21_L25_A0.6811.00
62_D69_L0.6771.00
63_P66_P0.6681.00
61_D64_E0.6681.00
79_A83_Q0.6671.00
28_P34_R0.6621.00
39_E70_A0.6581.00
72_A77_P0.6531.00
33_E54_I0.6501.00
19_G27_L0.6491.00
44_Q62_D0.6471.00
37_L46_L0.6331.00
82_A88_A0.6301.00
71_A75_P0.6251.00
32_R37_L0.6211.00
46_L60_L0.6161.00
33_E52_G0.6141.00
1_W4_R0.6111.00
11_R15_G0.6031.00
42_G64_E0.5971.00
2_L5_R0.5931.00
30_G36_V0.5931.00
37_L44_Q0.5891.00
39_E62_D0.5871.00
12_G15_G0.5841.00
64_E68_P0.5831.00
75_P78_A0.5771.00
4_R32_R0.5651.00
73_A76_A0.5611.00
25_A30_G0.5571.00
4_R10_G0.5551.00
50_T55_T0.5541.00
48_G55_T0.5531.00
5_R50_T0.5521.00
37_L45_L0.5471.00
44_Q61_D0.5451.00
67_E70_A0.5451.00
20_R23_V0.5431.00
73_A77_P0.5421.00
20_R44_Q0.5331.00
35_L47_L0.5321.00
30_G49_V0.5311.00
65_E70_A0.5261.00
65_E68_P0.5251.00
41_G65_E0.5251.00
31_P34_R0.5211.00
25_A28_P0.5211.00
67_E71_A0.5191.00
73_A78_A0.5131.00
71_A74_A0.5111.00
30_G34_R0.5101.00
4_R51_P0.5091.00
61_D65_E0.5081.00
41_G60_L0.5061.00
81_F84_L0.5061.00
79_A87_R0.5001.00
83_Q88_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3fqmA 2 0.9444 6.2 0.87 Contact Map
4o7oA 2 0.8889 5.3 0.874 Contact Map
4u98A 1 0.9333 3.9 0.882 Contact Map
4gwpC 1 0 3.5 0.885 Contact Map
3e19A 5 0.6111 3.1 0.888 Contact Map
1xrxA 3 0.3778 2.9 0.889 Contact Map
1fx7A 4 0.6222 2.8 0.89 Contact Map
2yweA 1 0 2.8 0.891 Contact Map
2h3gX 2 0.5333 2.6 0.893 Contact Map
3h4lA 2 0.3556 2.5 0.893 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0048 seconds.