GREMLIN Database
MrpF_PhaF - Multiple resistance and pH regulation protein F (MrpF / PhaF)
PFAM: PF04066 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 53 (51)
Sequences: 15868 (7266)
Seq/√Len: 1017.4
META: 0.887

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
21_L25_T3.6961.00
19_A34_A3.4361.00
15_V38_A3.2381.00
11_G41_G2.2451.00
11_G37_Y2.1061.00
8_D13_L1.7821.00
23_I31_L1.7801.00
9_L13_L1.5881.00
22_A31_L1.4151.00
13_L16_A1.4101.00
4_V48_F1.3331.00
8_D49_A1.3081.00
37_Y45_T1.1971.00
18_L37_Y1.1751.00
23_I26_G1.1461.00
21_L30_Y1.1421.00
20_L24_L1.1181.00
7_L44_G1.1061.00
16_A20_L1.1041.00
25_T30_Y1.1011.00
4_V8_D1.0731.00
8_D42_F1.0541.00
21_L24_L1.0091.00
43_V50_R1.0011.00
7_L11_G0.9811.00
10_L13_L0.9761.00
24_L27_R0.9661.00
45_T49_A0.9621.00
41_G44_G0.9261.00
4_V36_V0.9241.00
13_L17_L0.9221.00
15_V34_A0.9181.00
49_A52_L0.9041.00
40_L44_G0.8931.00
42_F45_T0.8741.00
23_I28_P0.8571.00
15_V37_Y0.8541.00
36_V40_L0.8421.00
22_A34_A0.8401.00
27_R30_Y0.8321.00
18_L33_V0.8011.00
7_L32_D0.7971.00
11_G14_A0.7901.00
18_L34_A0.7401.00
36_V39_L0.7271.00
19_A31_L0.7201.00
8_D45_T0.7191.00
22_A25_T0.7111.00
5_V8_D0.7011.00
37_Y50_R0.6941.00
14_A44_G0.6921.00
20_L42_F0.6901.00
7_L51_F0.6791.00
11_G48_F0.6731.00
44_G48_F0.6631.00
22_A30_Y0.6491.00
34_A38_A0.6341.00
9_L12_T0.6331.00
35_L38_A0.6291.00
39_L47_A0.6251.00
16_A47_A0.6251.00
18_L21_L0.6151.00
30_Y33_V0.6121.00
24_L28_P0.5801.00
33_V37_Y0.5801.00
46_V50_R0.5721.00
8_D12_T0.5711.00
5_V9_L0.5551.00
19_A38_A0.5531.00
14_A37_Y0.5511.00
5_V13_L0.5481.00
35_L47_A0.5431.00
14_A34_A0.5371.00
19_A22_A0.5301.00
21_L27_R0.5201.00
48_F51_F0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hi2A 1 0.4717 11.1 0.793 Contact Map
3sokA 1 0.4906 9.4 0.799 Contact Map
1oqwA 1 0.4906 9.3 0.8 Contact Map
2m7gA 1 0.4906 4.8 0.825 Contact Map
3j09A 2 0.9057 3.5 0.837 Contact Map
3j08A 2 0.9057 3.1 0.84 Contact Map
4bbjA 1 0.9057 2.7 0.846 Contact Map
3ossC 1 0.3396 1.5 0.866 Contact Map
3iusA 1 0.4151 1.4 0.868 Contact Map
4qmkA 2 1 1.4 0.868 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0036 seconds.