Mpp10 - PFAM28P - GREMLIN Contacts

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Mpp10 - Mpp10 protein

PFAM:	PF04006	Sequences: ATARPERFLSPQDGLAADFRSLTKTLYDLLKKLEKRSGRVPGSPLDELVVDGFDEEQIWQQLELQNDPVLDELERAIAELEKDEEDISLLDEEEEEESEEDEEEDEEEESEDEEEEEDEEEEDEEEEEEEEEEDEEEDEEDLEDESDDEDSDEDEDIEEEEQQSKEEKKKEDKSGVDDGFFKLDEFNKFLEEEEKEDARGDDEDSDEEDIDWFADPDSDDEDEEEGKNARDIKYKDFFDPPDKKKDKKKKKDEEDDDDEEEDEEEEEEDEERAMDDVDRDLFEDEDEEEDEEDEEDEDEADLSTHEKRQAKLAEEIRKLEAENLAKKPWTLKGEVTAAKRPENSLLEEDLDFEHAGKPVPVITEEVTESLEDLIKQRILDQAFDDVVRRRPPDEDAFEYKKRLELDDEKSKKSLAEIYEQEYLKKTDVDKKDEKLNKEHKEIEKLWKSLFLKLDALSNFHFTPKPPVPEIKVVSNVPAIAMEEAAPVAVSDASLLAPEEVYEKKKGDVKAKAELTREDKKRRRRKKKRRKRKKRKEKEKRQKLLEKLKPGKKKSKAAKKEKLKSLTKKGGVTVIGKKGKDKALKSSQAFFSQLQDQV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	597 (572)
Sequences:	576 (465)
Seq/√Len:	19.4
META:	0.078

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
172_D	175_G	6.522	1.00
24_K	28_D	5.076	1.00
172_D	176_V	4.995	1.00
412_K	420_Q	4.596	1.00
186_F	189_F	4.033	1.00
563_K	566_T	3.739	1.00
173_K	176_V	3.489	1.00
234_Y	238_F	3.488	1.00
561_K	565_L	3.321	1.00
106_E	111_E	2.868	0.99
561_K	566_T	2.861	0.99
557_A	565_L	2.848	0.99
326_K	332_K	2.788	0.99
417_I	421_E	2.765	0.98
446_W	450_F	2.659	0.98
170_K	175_G	2.576	0.98
367_T	370_L	2.574	0.98
558_K	561_K	2.555	0.97
273_A	276_D	2.554	0.97
234_Y	237_F	2.541	0.97
125_E	312_L	2.436	0.97
109_E	115_E	2.422	0.96
566_T	569_G	2.371	0.96
557_A	561_K	2.363	0.96
105_D	109_E	2.354	0.96
573_V	576_K	2.339	0.96
565_L	568_K	2.332	0.96
336_T	339_K	2.327	0.95
302_L	310_A	2.298	0.95
573_V	578_G	2.251	0.95
205_S	209_D	2.241	0.94
309_Q	433_E	2.215	0.94
182_K	185_E	2.195	0.94
103_E	114_E	2.151	0.93
132_E	136_E	2.148	0.93
94_E	113_E	2.146	0.93
125_E	223_E	2.080	0.92
369_S	372_D	2.064	0.92
249_K	252_D	2.040	0.91
116_E	223_E	2.013	0.90
203_E	207_E	2.000	0.90
575_G	579_K	1.987	0.90
11_P	15_L	1.957	0.89
558_K	566_T	1.948	0.89
194_E	322_E	1.940	0.89
121_E	125_E	1.924	0.88
558_K	565_L	1.922	0.88
31_K	34_E	1.905	0.88
554_S	558_K	1.898	0.88
279_R	282_F	1.884	0.87
420_Q	458_N	1.868	0.87
26_L	31_K	1.839	0.86
120_E	123_D	1.807	0.85
566_T	570_G	1.803	0.85
370_L	518_D	1.798	0.85
170_K	176_V	1.790	0.84
449_L	452_K	1.787	0.84
158_E	161_E	1.770	0.84
348_E	464_K	1.761	0.83
565_L	572_T	1.750	0.83
327_K	529_R	1.741	0.83
341_P	344_S	1.732	0.82
169_K	172_D	1.730	0.82
48_L	65_Q	1.710	0.81
560_E	565_L	1.707	0.81
564_S	570_G	1.703	0.81
558_K	572_T	1.698	0.81
460_H	481_M	1.688	0.81
23_T	26_L	1.682	0.80
191_E	194_E	1.676	0.80
469_E	484_A	1.674	0.80
383_F	412_K	1.674	0.80
310_A	500_V	1.673	0.80
140_E	144_D	1.671	0.80
177_D	182_K	1.670	0.80
125_E	206_D	1.669	0.80
194_E	223_E	1.652	0.79
570_G	573_V	1.652	0.79
107_E	113_E	1.634	0.78
16_A	31_K	1.619	0.78
235_K	241_P	1.613	0.77
156_D	224_E	1.599	0.77
284_D	287_E	1.591	0.76
169_K	176_V	1.589	0.76
566_T	573_V	1.586	0.76
319_L	421_E	1.577	0.76
280_D	284_D	1.577	0.76
362_I	366_V	1.573	0.75
541_Q	544_L	1.571	0.75
273_A	280_D	1.563	0.75
23_T	28_D	1.541	0.74
103_E	107_E	1.538	0.74
317_R	422_Y	1.525	0.73
126_E	154_D	1.522	0.73
323_N	327_K	1.521	0.73
295_E	300_A	1.518	0.73
284_D	288_E	1.511	0.72
554_S	557_A	1.508	0.72
560_E	566_T	1.494	0.72
120_E	125_E	1.484	0.71
452_K	494_L	1.481	0.71
557_A	560_E	1.478	0.71
223_E	285_E	1.475	0.71
295_E	301_D	1.474	0.71
557_A	566_T	1.472	0.70
126_E	362_I	1.472	0.70
97_E	103_E	1.472	0.70
260_E	263_E	1.471	0.70
326_K	335_V	1.471	0.70
105_D	110_S	1.470	0.70
252_D	255_D	1.470	0.70
14_G	26_L	1.467	0.70
463_P	482_E	1.464	0.70
220_D	223_E	1.463	0.70
276_D	281_L	1.463	0.70
133_E	141_D	1.459	0.70
557_A	564_S	1.451	0.69
560_E	564_S	1.440	0.69
112_D	209_D	1.437	0.69
514_L	522_R	1.437	0.69
570_G	575_G	1.432	0.68
362_I	552_K	1.429	0.68
174_S	183_L	1.428	0.68
177_D	183_L	1.420	0.68
106_E	149_E	1.417	0.67
143_E	152_D	1.415	0.67
110_S	114_E	1.412	0.67
57_Q	409_K	1.403	0.67
518_D	521_R	1.399	0.66
345_L	458_N	1.397	0.66
91_D	99_E	1.395	0.66
279_R	283_E	1.391	0.66
156_D	159_E	1.390	0.66
272_R	276_D	1.387	0.66
566_T	578_G	1.386	0.66
270_E	273_A	1.384	0.66
247_K	250_K	1.381	0.65
273_A	279_R	1.380	0.65
16_A	27_Y	1.379	0.65
57_Q	341_P	1.377	0.65
364_E	370_L	1.377	0.65
132_E	135_E	1.376	0.65
130_E	134_D	1.373	0.65
187_N	190_L	1.366	0.64
19_F	22_L	1.366	0.64
560_E	570_G	1.362	0.64
553_K	560_E	1.361	0.64
472_V	480_A	1.357	0.64
254_E	257_D	1.356	0.64
288_E	295_E	1.356	0.64
110_S	119_E	1.355	0.64
8_F	27_Y	1.354	0.64
574_I	578_G	1.348	0.63
419_E	457_S	1.348	0.63
145_E	291_E	1.346	0.63
125_E	229_A	1.346	0.63
141_D	152_D	1.341	0.63
562_L	579_K	1.337	0.63
381_Q	399_Y	1.337	0.63
561_K	569_G	1.334	0.63
178_D	415_A	1.334	0.63
56_E	59_W	1.333	0.63
576_K	579_K	1.333	0.63
557_A	563_K	1.327	0.62
92_E	99_E	1.325	0.62
561_K	564_S	1.323	0.62
553_K	557_A	1.318	0.62
99_E	104_E	1.316	0.61
276_D	279_R	1.314	0.61
570_G	576_K	1.311	0.61
460_H	464_K	1.309	0.61
305_H	309_Q	1.308	0.61
267_E	270_E	1.299	0.60
572_T	578_G	1.297	0.60
270_E	276_D	1.295	0.60
303_S	481_M	1.288	0.60
319_L	523_R	1.284	0.60
212_W	373_L	1.283	0.59
174_S	177_D	1.281	0.59
26_L	30_L	1.281	0.59
108_E	111_E	1.281	0.59
8_F	11_P	1.281	0.59
274_M	278_D	1.274	0.59
565_L	578_G	1.274	0.59
324_L	459_F	1.271	0.59
272_R	279_R	1.270	0.59
251_K	254_E	1.265	0.58
102_E	109_E	1.265	0.58
107_E	117_E	1.264	0.58
24_K	31_K	1.262	0.58
336_T	461_F	1.256	0.58
186_F	190_L	1.252	0.58
561_K	572_T	1.250	0.57
83_D	87_I	1.238	0.57
461_F	562_L	1.234	0.56
565_L	569_G	1.233	0.56
471_K	474_S	1.232	0.56
341_P	405_L	1.232	0.56
542_K	545_E	1.232	0.56
15_L	22_L	1.229	0.56
183_L	394_E	1.225	0.56
103_E	335_V	1.223	0.56
438_E	478_A	1.220	0.56
566_T	574_I	1.217	0.55
129_E	140_E	1.216	0.55
484_A	517_E	1.214	0.55
127_E	131_E	1.213	0.55
297_E	301_D	1.211	0.55
276_D	280_D	1.206	0.55
182_K	373_L	1.205	0.55
420_Q	423_L	1.202	0.54
553_K	566_T	1.197	0.54
421_E	555_K	1.189	0.54
102_E	122_E	1.189	0.54
302_L	468_P	1.187	0.53
103_E	109_E	1.187	0.53
506_G	524_R	1.187	0.53
437_K	461_F	1.186	0.53
256_D	259_E	1.183	0.53
49_V	411_K	1.182	0.53
98_S	145_E	1.180	0.53
170_K	173_K	1.180	0.53
29_L	32_K	1.173	0.53
89_L	100_E	1.170	0.52
562_L	576_K	1.169	0.52
305_H	366_V	1.168	0.52
294_E	297_E	1.167	0.52
15_L	24_K	1.167	0.52
514_L	518_D	1.163	0.52
541_Q	545_E	1.160	0.52
521_R	524_R	1.157	0.52
337_A	500_V	1.155	0.51
108_E	146_S	1.154	0.51
138_D	142_L	1.153	0.51
207_E	336_T	1.153	0.51
250_K	253_E	1.152	0.51
273_A	278_D	1.146	0.51
441_E	445_L	1.145	0.51
296_D	301_D	1.144	0.51
494_L	515_T	1.143	0.51
113_E	119_E	1.141	0.51
149_E	156_D	1.137	0.50
27_Y	31_K	1.137	0.50
278_D	281_L	1.135	0.50
376_Q	380_D	1.130	0.50
397_F	400_K	1.129	0.50
353_E	450_F	1.123	0.49
122_E	222_D	1.122	0.49
494_L	531_R	1.122	0.49
298_D	301_D	1.111	0.49
342_E	518_D	1.105	0.48
554_S	565_L	1.105	0.48
285_E	288_E	1.104	0.48
294_E	298_D	1.103	0.48
141_D	144_D	1.096	0.48
123_D	130_E	1.092	0.47
336_T	354_H	1.090	0.47
113_E	155_E	1.088	0.47
128_E	146_S	1.085	0.47
160_E	167_E	1.083	0.47
82_K	106_E	1.082	0.47
563_K	570_G	1.082	0.47
238_F	241_P	1.079	0.47
128_E	140_E	1.075	0.46
104_E	107_E	1.073	0.46
109_E	493_S	1.072	0.46
125_E	274_M	1.071	0.46
104_E	219_D	1.070	0.46
123_D	156_D	1.068	0.46
102_E	150_D	1.067	0.46
146_S	165_K	1.067	0.46
117_E	120_E	1.066	0.46
133_E	146_S	1.065	0.46
438_E	445_L	1.063	0.46
561_K	568_K	1.062	0.45
91_D	102_E	1.061	0.45
461_F	490_S	1.057	0.45
67_D	492_A	1.055	0.45
131_E	140_E	1.051	0.45
466_P	530_K	1.051	0.45
328_P	348_E	1.050	0.45
103_E	121_E	1.044	0.44
439_H	442_I	1.042	0.44
345_L	442_I	1.037	0.44
436_N	439_H	1.034	0.44
406_D	531_R	1.029	0.43
123_D	131_E	1.027	0.43
312_L	362_I	1.025	0.43
561_K	578_G	1.024	0.43
257_D	261_E	1.022	0.43
140_E	146_S	1.021	0.43
43_S	65_Q	1.019	0.43
295_E	298_D	1.017	0.43
562_L	566_T	1.017	0.43
270_E	278_D	1.014	0.42
73_L	154_D	1.013	0.42
363_T	477_P	1.012	0.42
24_K	29_L	1.010	0.42
107_E	110_S	1.010	0.42
178_D	181_F	1.009	0.42
343_N	347_E	1.008	0.42
393_D	461_F	1.007	0.42
553_K	579_K	1.007	0.42
114_E	120_E	1.004	0.42
136_E	139_E	0.998	0.41
277_V	281_L	0.998	0.41
556_A	560_E	0.997	0.41
204_D	207_E	0.991	0.41
129_E	132_E	0.990	0.41
150_D	156_D	0.989	0.41
56_E	520_K	0.988	0.41
406_D	515_T	0.987	0.41
69_V	73_L	0.985	0.41
132_E	142_L	0.983	0.41
323_N	326_K	0.981	0.40
234_Y	240_P	0.980	0.40
58_I	182_K	0.980	0.40
136_E	143_E	0.979	0.40
98_S	111_E	0.979	0.40
24_K	30_L	0.977	0.40
34_E	37_S	0.977	0.40
148_D	151_S	0.976	0.40
472_V	477_P	0.974	0.40
289_E	292_E	0.973	0.40
516_R	519_K	0.973	0.40
190_L	359_V	0.971	0.40
470_I	473_V	0.970	0.40
205_S	208_E	0.970	0.40
272_R	278_D	0.969	0.40
307_K	493_S	0.966	0.39
381_Q	530_K	0.966	0.39
248_K	252_D	0.965	0.39
121_E	445_L	0.965	0.39
415_A	495_L	0.965	0.39
22_L	27_Y	0.964	0.39
192_E	305_H	0.963	0.39
79_E	102_E	0.960	0.39
110_S	116_E	0.960	0.39
17_A	21_S	0.957	0.39
359_V	498_E	0.955	0.39
228_N	312_L	0.953	0.39
68_P	488_A	0.950	0.39
28_D	479_I	0.946	0.38
306_E	481_M	0.944	0.38
107_E	162_Q	0.943	0.38
563_K	578_G	0.939	0.38
560_E	563_K	0.938	0.38
563_K	572_T	0.937	0.38
185_E	188_K	0.937	0.38
119_E	124_E	0.936	0.38
274_M	282_F	0.935	0.38
327_K	577_K	0.935	0.38
244_K	324_L	0.935	0.38
573_V	579_K	0.933	0.37
553_K	573_V	0.932	0.37
197_D	475_N	0.931	0.37
570_G	574_I	0.929	0.37
274_M	277_V	0.929	0.37
127_E	137_E	0.926	0.37
348_E	415_A	0.925	0.37
566_T	572_T	0.924	0.37
178_D	460_H	0.922	0.37
177_D	413_S	0.922	0.37
182_K	485_A	0.921	0.37
386_V	473_V	0.919	0.37
410_S	490_S	0.918	0.37
111_E	151_S	0.917	0.37
226_G	229_A	0.917	0.37
131_E	139_E	0.913	0.36
250_K	254_E	0.913	0.36
562_L	565_L	0.913	0.36
540_R	543_L	0.912	0.36
34_E	61_Q	0.912	0.36
278_D	282_F	0.908	0.36
160_E	163_Q	0.907	0.36
416_E	419_E	0.907	0.36
189_F	194_E	0.905	0.36
291_E	299_E	0.903	0.36
183_L	193_E	0.902	0.36
248_K	274_M	0.901	0.36
273_A	282_F	0.901	0.36
268_E	272_R	0.899	0.35
327_K	392_P	0.897	0.35
118_D	131_E	0.894	0.35
498_E	509_K	0.893	0.35
438_E	488_A	0.892	0.35
9_L	13_D	0.888	0.35
327_K	422_Y	0.887	0.35
29_L	34_E	0.885	0.35
337_A	532_K	0.885	0.35
566_T	579_K	0.884	0.35
413_S	416_E	0.884	0.35
561_K	579_K	0.882	0.34
30_L	43_S	0.880	0.34
53_F	57_Q	0.878	0.34
276_D	422_Y	0.878	0.34
222_D	318_K	0.876	0.34
107_E	121_E	0.873	0.34
12_Q	15_L	0.871	0.34
159_E	162_Q	0.871	0.34
543_L	547_L	0.871	0.34
239_D	243_K	0.870	0.34
161_E	165_K	0.869	0.34
202_D	500_V	0.869	0.34
557_A	570_G	0.866	0.34
102_E	271_E	0.864	0.33
48_L	344_S	0.864	0.33
178_D	306_E	0.864	0.33
460_H	465_P	0.864	0.33
314_E	434_K	0.862	0.33
462_T	527_K	0.860	0.33
169_K	175_G	0.857	0.33
102_E	105_D	0.855	0.33
176_V	518_D	0.854	0.33
125_E	148_D	0.854	0.33
178_D	234_Y	0.854	0.33
183_L	495_L	0.853	0.33
55_E	500_V	0.853	0.33
209_D	269_D	0.853	0.33
139_E	142_L	0.851	0.33
309_Q	458_N	0.850	0.33
101_D	141_D	0.848	0.33
135_E	144_D	0.842	0.32
107_E	119_E	0.842	0.32
557_A	573_V	0.842	0.32
439_H	511_K	0.842	0.32
13_D	23_T	0.842	0.32
562_L	570_G	0.837	0.32
294_E	301_D	0.837	0.32
307_K	511_K	0.837	0.32
21_S	25_T	0.832	0.32
71_D	102_E	0.832	0.32
15_L	28_D	0.831	0.32
563_K	568_K	0.830	0.32
394_E	424_K	0.827	0.31
126_E	139_E	0.826	0.31
19_F	30_L	0.826	0.31
144_D	158_E	0.824	0.31
553_K	558_K	0.823	0.31
386_V	455_A	0.822	0.31
344_S	475_N	0.822	0.31
565_L	570_G	0.820	0.31
413_S	419_E	0.819	0.31
562_L	572_T	0.818	0.31
455_A	465_P	0.818	0.31
125_E	204_D	0.817	0.31
12_Q	16_A	0.817	0.31
56_E	514_L	0.816	0.31
55_E	68_P	0.813	0.31
557_A	562_L	0.812	0.31
205_S	275_D	0.812	0.31
368_E	376_Q	0.810	0.30
280_D	306_E	0.810	0.30
61_Q	194_E	0.807	0.30
295_E	299_E	0.807	0.30
53_F	570_G	0.803	0.30
194_E	240_P	0.801	0.30
129_E	133_E	0.799	0.30
235_K	477_P	0.798	0.30
20_R	23_T	0.797	0.30
178_D	521_R	0.796	0.30
346_L	410_S	0.795	0.30
268_E	275_D	0.793	0.30
48_L	327_K	0.792	0.29
220_D	260_E	0.792	0.29
58_I	61_Q	0.790	0.29
205_S	266_E	0.788	0.29
137_E	143_E	0.787	0.29
353_E	448_S	0.786	0.29
47_E	472_V	0.785	0.29
25_T	29_L	0.785	0.29
109_E	116_E	0.783	0.29
511_K	514_L	0.782	0.29
436_N	440_K	0.781	0.29
121_E	124_E	0.781	0.29
22_L	26_L	0.780	0.29
251_K	255_D	0.779	0.29
231_D	461_F	0.779	0.29
556_A	563_K	0.776	0.29
154_D	157_I	0.776	0.29
60_Q	488_A	0.776	0.29
309_Q	469_E	0.775	0.29
500_V	542_K	0.774	0.29
158_E	165_K	0.774	0.29
195_K	200_G	0.773	0.28
286_D	289_E	0.773	0.28
152_D	158_E	0.773	0.28
554_S	575_G	0.772	0.28
247_K	253_E	0.772	0.28
150_D	288_E	0.770	0.28
126_E	134_D	0.769	0.28
332_K	339_K	0.768	0.28
12_Q	22_L	0.767	0.28
202_D	233_K	0.766	0.28
553_K	561_K	0.766	0.28
545_E	549_P	0.761	0.28
118_D	122_E	0.757	0.28
120_E	124_E	0.757	0.28
125_E	292_E	0.757	0.28
348_E	439_H	0.756	0.28
144_D	149_E	0.756	0.28
430_K	433_E	0.753	0.27
80_L	552_K	0.752	0.27
28_D	31_K	0.749	0.27
506_G	527_K	0.748	0.27
152_D	157_I	0.748	0.27
134_D	138_D	0.747	0.27
111_E	224_E	0.747	0.27
349_D	383_F	0.746	0.27
566_T	576_K	0.746	0.27
111_E	146_S	0.744	0.27
311_K	314_E	0.742	0.27
60_Q	518_D	0.742	0.27
107_E	111_E	0.741	0.27
19_F	25_T	0.740	0.27
185_E	361_V	0.740	0.27
469_E	474_S	0.740	0.27
49_V	520_K	0.739	0.27
46_D	379_L	0.733	0.26
309_Q	506_G	0.732	0.26
151_S	156_D	0.732	0.26
187_N	449_L	0.731	0.26
195_K	312_L	0.730	0.26
571_V	575_G	0.729	0.26
222_D	317_R	0.727	0.26
95_E	106_E	0.727	0.26
90_L	94_E	0.726	0.26
477_P	490_S	0.725	0.26
141_D	218_S	0.725	0.26
75_R	337_A	0.725	0.26
181_F	194_E	0.724	0.26
307_K	327_K	0.722	0.26
322_E	349_D	0.721	0.26
11_P	29_L	0.720	0.26
98_S	110_S	0.720	0.26
372_D	452_K	0.719	0.26
190_L	407_D	0.719	0.26
8_F	12_Q	0.719	0.26
392_P	395_D	0.718	0.26
134_D	140_E	0.717	0.26
94_E	112_D	0.716	0.26
127_E	505_K	0.715	0.26
556_A	562_L	0.714	0.26
273_A	277_V	0.713	0.25
105_D	245_K	0.712	0.25
376_Q	382_A	0.712	0.25
346_L	364_E	0.712	0.25
107_E	115_E	0.709	0.25
126_E	165_K	0.709	0.25
446_W	567_K	0.708	0.25
124_E	268_E	0.708	0.25
9_L	16_A	0.708	0.25
479_I	509_K	0.706	0.25
307_K	444_K	0.706	0.25
82_K	487_V	0.705	0.25
544_L	548_K	0.705	0.25
293_D	297_E	0.705	0.25
303_S	307_K	0.704	0.25
234_Y	413_S	0.703	0.25
131_E	266_E	0.703	0.25
274_M	279_R	0.702	0.25
266_E	289_E	0.702	0.25
267_E	271_E	0.702	0.25
270_E	284_D	0.701	0.25
557_A	578_G	0.701	0.25
380_D	450_F	0.701	0.25
493_S	571_V	0.700	0.25
276_D	355_A	0.700	0.25
140_E	221_E	0.699	0.25
334_E	340_R	0.698	0.25
149_E	157_I	0.698	0.25
233_K	238_F	0.698	0.25
117_E	121_E	0.697	0.25
565_L	573_V	0.696	0.25
562_L	567_K	0.696	0.25
246_D	253_E	0.695	0.25
235_K	308_R	0.694	0.25
146_S	284_D	0.693	0.25
239_D	242_D	0.691	0.24
319_L	356_G	0.687	0.24
431_K	436_N	0.686	0.24
364_E	495_L	0.684	0.24
345_L	482_E	0.682	0.24
135_E	139_E	0.680	0.24
22_L	30_L	0.676	0.24
323_N	489_V	0.676	0.24
312_L	344_S	0.675	0.24
554_S	566_T	0.675	0.24
555_K	560_E	0.675	0.24
351_D	361_V	0.674	0.24
283_E	457_S	0.674	0.24
563_K	579_K	0.674	0.24
168_K	209_D	0.673	0.24
148_D	373_L	0.672	0.24
528_R	532_K	0.670	0.23
45_L	78_A	0.670	0.23
208_E	527_K	0.670	0.23
108_E	114_E	0.669	0.23
13_D	16_A	0.668	0.23
126_E	145_E	0.668	0.23
522_R	530_K	0.668	0.23
25_T	30_L	0.666	0.23
150_D	164_S	0.666	0.23
389_R	475_N	0.666	0.23
406_D	430_K	0.665	0.23
70_L	354_H	0.664	0.23
345_L	383_F	0.664	0.23
110_S	224_E	0.662	0.23
53_F	459_F	0.662	0.23
245_K	248_K	0.661	0.23
522_R	528_R	0.661	0.23
493_S	532_K	0.660	0.23
109_E	264_E	0.659	0.23
53_F	503_K	0.658	0.23
91_D	113_E	0.658	0.23
462_T	494_L	0.657	0.23
14_G	17_A	0.656	0.23
111_E	114_E	0.656	0.23
67_D	229_A	0.655	0.23
458_N	498_E	0.654	0.23
394_E	501_Y	0.653	0.23
540_R	554_S	0.652	0.23
520_K	524_R	0.651	0.23
13_D	17_A	0.651	0.23
448_S	515_T	0.649	0.22
196_E	199_R	0.648	0.22
58_I	498_E	0.647	0.22
307_K	515_T	0.647	0.22
570_G	578_G	0.647	0.22
282_F	288_E	0.644	0.22
114_E	424_K	0.643	0.22
131_E	136_E	0.643	0.22
567_K	570_G	0.642	0.22
129_E	138_D	0.641	0.22
94_E	107_E	0.641	0.22
343_N	475_N	0.641	0.22
347_E	360_P	0.641	0.22
509_K	514_L	0.640	0.22
423_L	427_D	0.640	0.22
186_F	359_V	0.639	0.22
406_D	572_T	0.638	0.22
380_D	413_S	0.637	0.22
111_E	258_D	0.637	0.22
95_E	262_D	0.633	0.22
132_E	139_E	0.633	0.22
152_D	161_E	0.633	0.22
48_L	347_E	0.631	0.22
553_K	563_K	0.631	0.22
358_P	383_F	0.630	0.22
19_F	23_T	0.630	0.22
563_K	574_I	0.630	0.22
385_D	459_F	0.630	0.22
274_M	281_L	0.630	0.22
15_L	20_R	0.629	0.22
124_E	286_D	0.628	0.22
337_A	527_K	0.627	0.22
47_E	309_Q	0.627	0.22
15_L	30_L	0.626	0.21
202_D	337_A	0.626	0.21
142_L	145_E	0.626	0.21
215_D	506_G	0.624	0.21
344_S	489_V	0.623	0.21
385_D	478_A	0.623	0.21
291_E	294_E	0.621	0.21
452_K	486_P	0.621	0.21
556_A	570_G	0.619	0.21
530_K	534_R	0.617	0.21
18_D	21_S	0.617	0.21
32_K	37_S	0.617	0.21
362_I	433_E	0.617	0.21
160_E	220_D	0.616	0.21
118_D	298_D	0.616	0.21
345_L	524_R	0.615	0.21
203_E	510_A	0.615	0.21
58_I	91_D	0.614	0.21
353_E	399_Y	0.613	0.21
290_D	301_D	0.612	0.21
113_E	125_E	0.611	0.21
453_L	486_P	0.611	0.21
320_E	363_T	0.610	0.21
27_Y	33_L	0.608	0.21
66_N	383_F	0.608	0.21
108_E	112_D	0.607	0.21
22_L	25_T	0.607	0.21
323_N	509_K	0.607	0.21
413_S	539_K	0.606	0.21
556_A	566_T	0.606	0.21
152_D	165_K	0.605	0.21
106_E	275_D	0.605	0.21
88_S	103_E	0.605	0.21
45_L	184_D	0.603	0.21
129_E	188_K	0.603	0.21
209_D	443_E	0.602	0.20
337_A	577_K	0.601	0.20
119_E	296_D	0.601	0.20
177_D	184_D	0.600	0.20
561_K	576_K	0.600	0.20
146_S	223_E	0.600	0.20
566_T	575_G	0.599	0.20
98_S	500_V	0.599	0.20
74_E	520_K	0.598	0.20
177_D	439_H	0.596	0.20
104_E	118_D	0.595	0.20
343_N	434_K	0.595	0.20
435_L	484_A	0.594	0.20
329_W	333_G	0.594	0.20
88_S	91_D	0.593	0.20
524_R	527_K	0.592	0.20
101_D	132_E	0.590	0.20
388_R	407_D	0.590	0.20
424_K	468_P	0.590	0.20
50_V	271_E	0.589	0.20
302_L	436_N	0.589	0.20
113_E	117_E	0.589	0.20
477_P	492_A	0.587	0.20
565_L	576_K	0.584	0.20
157_I	160_E	0.583	0.20
217_D	323_N	0.581	0.20
157_I	163_Q	0.580	0.20
469_E	498_E	0.579	0.20
118_D	150_D	0.578	0.19
177_D	446_W	0.578	0.19
481_M	542_K	0.578	0.19
416_E	527_K	0.577	0.19
153_E	161_E	0.577	0.19
313_A	514_L	0.577	0.19
125_E	196_E	0.576	0.19
128_E	539_K	0.575	0.19
307_K	451_L	0.574	0.19
157_I	307_K	0.574	0.19
142_L	159_E	0.573	0.19
170_K	174_S	0.573	0.19
428_V	431_K	0.571	0.19
222_D	571_V	0.570	0.19
245_K	250_K	0.570	0.19
281_L	284_D	0.570	0.19
558_K	563_K	0.569	0.19
418_Y	456_L	0.568	0.19
116_E	123_D	0.567	0.19
152_D	257_D	0.567	0.19
552_K	564_S	0.567	0.19
407_D	435_L	0.566	0.19
151_S	321_A	0.566	0.19
114_E	119_E	0.565	0.19
333_G	340_R	0.565	0.19
135_E	145_E	0.564	0.19
404_E	514_L	0.563	0.19
336_T	364_E	0.563	0.19
134_D	143_E	0.563	0.19
104_E	163_Q	0.562	0.19
498_E	501_Y	0.562	0.19
380_D	490_S	0.560	0.19
107_E	149_E	0.559	0.19
312_L	388_R	0.559	0.19
450_F	459_F	0.557	0.19
363_T	482_E	0.557	0.19
221_E	224_E	0.557	0.19
91_D	118_D	0.556	0.19
98_S	289_E	0.554	0.19
34_E	38_G	0.553	0.18
181_F	190_L	0.552	0.18
14_G	19_F	0.552	0.18
91_D	500_V	0.552	0.18
66_N	498_E	0.552	0.18
284_D	300_A	0.552	0.18
124_E	185_E	0.551	0.18
504_K	531_R	0.551	0.18
407_D	484_A	0.551	0.18
348_E	433_E	0.550	0.18
554_S	573_V	0.550	0.18
399_Y	407_D	0.550	0.18
102_E	557_A	0.550	0.18
321_A	380_D	0.550	0.18
84_E	118_D	0.549	0.18
564_S	567_K	0.549	0.18
51_D	97_E	0.548	0.18
106_E	156_D	0.548	0.18
572_T	576_K	0.547	0.18
384_D	469_E	0.547	0.18
543_L	548_K	0.547	0.18
23_T	30_L	0.547	0.18
332_K	335_V	0.547	0.18
554_S	578_G	0.547	0.18
561_K	570_G	0.547	0.18
185_E	457_S	0.546	0.18
411_K	527_K	0.546	0.18
128_E	132_E	0.546	0.18
277_V	280_D	0.545	0.18
90_L	117_E	0.545	0.18
472_V	504_K	0.544	0.18
350_L	424_K	0.543	0.18
314_E	318_K	0.538	0.18
45_L	49_V	0.538	0.18
117_E	123_D	0.538	0.18
235_K	239_D	0.538	0.18
214_A	343_N	0.538	0.18
318_K	337_A	0.537	0.18
564_S	575_G	0.536	0.18
411_K	459_F	0.535	0.18
237_F	361_V	0.534	0.18
270_E	282_F	0.534	0.18
561_K	573_V	0.534	0.18
95_E	103_E	0.534	0.18
153_E	165_K	0.533	0.18
131_E	135_E	0.532	0.18
26_L	29_L	0.532	0.18
311_K	500_V	0.531	0.18
558_K	568_K	0.531	0.18
50_V	515_T	0.531	0.18
181_F	308_R	0.531	0.18
135_E	141_D	0.530	0.18
270_E	337_A	0.529	0.18
262_D	269_D	0.529	0.18
553_K	559_K	0.529	0.18
62_L	165_K	0.528	0.18
129_E	151_S	0.528	0.18
385_D	399_Y	0.528	0.18
362_I	549_P	0.528	0.18
253_E	256_D	0.528	0.18
481_M	485_A	0.526	0.17
405_L	409_K	0.526	0.17
20_R	29_L	0.525	0.17
559_K	566_T	0.525	0.17
256_D	270_E	0.524	0.17
427_D	461_F	0.524	0.17
513_E	523_R	0.524	0.17
104_E	117_E	0.523	0.17
269_D	272_R	0.519	0.17
109_E	118_D	0.518	0.17
231_D	440_K	0.518	0.17
274_M	440_K	0.516	0.17
220_D	244_K	0.515	0.17
10_S	20_R	0.514	0.17
294_E	423_L	0.513	0.17
249_K	543_L	0.512	0.17
133_E	222_D	0.511	0.17
11_P	18_D	0.510	0.17
69_V	383_F	0.510	0.17
57_Q	61_Q	0.510	0.17
493_S	502_E	0.509	0.17
412_K	528_R	0.509	0.17
434_K	570_G	0.508	0.17
177_D	389_R	0.508	0.17
376_Q	515_T	0.508	0.17
111_E	269_D	0.506	0.17
94_E	273_A	0.505	0.17
473_V	528_R	0.505	0.17
187_N	415_A	0.505	0.17
93_E	99_E	0.504	0.17
495_L	515_T	0.504	0.17
244_K	247_K	0.502	0.17
63_E	66_N	0.502	0.17
116_E	247_K	0.501	0.17
9_L	12_Q	0.501	0.17
143_E	204_D	0.501	0.17
93_E	97_E	0.500	0.17
60_Q	475_N	0.500	0.17
309_Q	312_L	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4fp9B	2	0.1374	81.7	0.973	Contact Map
4u7aA	1	0.0519	46.6	0.979	Contact Map
4w8pA	2	0.139	17.6	0.983	Contact Map
2gpvG	1	0.0201	14.6	0.983	Contact Map
4gdzA	3	0.0771	12.2	0.984	Contact Map
4w8pB	1	0.0352	11.2	0.984	Contact Map
2ovmB	1	0.0184	8.8	0.985	Contact Map
2yv4A	1	0.1055	7.2	0.985	Contact Map
4jrbA	1	0.1022	6.8	0.986	Contact Map
2mvmA	1	0.0737	6.5	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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