GREMLIN Database
FlgD - Flagellar hook capping protein - N-terminal region
PFAM: PF03963 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 75 (67)
Sequences: 26863 (17822)
Seq/√Len: 2177.2
META: 0.905

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
66_L69_L3.4061.00
26_L30_D2.8701.00
46_N49_D2.5941.00
62_S66_L2.4971.00
27_G30_D2.2861.00
49_D52_Q2.2031.00
52_Q55_A2.1721.00
65_Q70_N2.1321.00
69_L73_L2.0401.00
43_D46_N1.7821.00
64_E68_N1.7311.00
37_T40_Q1.6221.00
55_A59_Q1.6111.00
48_M51_T1.5181.00
37_T41_N1.5091.00
67_T71_T1.4781.00
59_Q62_S1.4441.00
28_K64_E1.4321.00
33_K37_T1.3241.00
50_N54_T1.2801.00
71_T74_E1.2501.00
68_N71_T1.1811.00
25_A30_D1.1571.00
10_T13_T1.0921.00
29_D33_K1.0691.00
69_L72_S1.0221.00
61_S65_Q1.0201.00
54_T57_L1.0201.00
30_D33_K1.0171.00
68_N74_E1.0161.00
70_N74_E1.0111.00
68_N72_S1.0091.00
65_Q68_N1.0081.00
38_Q51_T0.9831.00
32_L36_V0.9581.00
39_L53_F0.9571.00
55_A58_A0.9521.00
22_S25_A0.9491.00
21_T24_S0.9361.00
34_L54_T0.8931.00
51_T54_T0.8791.00
53_F60_F0.8701.00
67_T70_N0.8551.00
33_K36_V0.8551.00
11_S14_S0.8531.00
16_S19_S0.8401.00
52_Q56_Q0.8401.00
10_T14_S0.8221.00
17_S20_A0.8081.00
19_S22_S0.7931.00
18_S21_T0.7901.00
61_S67_T0.7821.00
44_P47_P0.7771.00
24_S27_G0.7671.00
12_S15_S0.7581.00
11_S15_S0.7501.00
8_S11_S0.7481.00
13_T16_S0.7471.00
28_K68_N0.7421.00
64_E67_T0.7411.00
36_V40_Q0.7341.00
38_Q50_N0.7131.00
20_A23_S0.7091.00
33_K40_Q0.7061.00
9_T13_T0.7051.00
28_K31_F0.6991.00
25_A28_K0.6931.00
53_F57_L0.6891.00
14_S18_S0.6771.00
23_S26_L0.6771.00
61_S70_N0.6711.00
15_S18_S0.6661.00
21_T25_A0.6561.00
9_T12_S0.6511.00
42_Q47_P0.6491.00
28_K44_P0.6471.00
58_A63_V0.6351.00
35_L53_F0.6351.00
70_N73_L0.6341.00
61_S64_E0.6321.00
15_S19_S0.6291.00
28_K36_V0.6181.00
66_L73_L0.6171.00
51_T55_A0.6051.00
60_F63_V0.5961.00
14_S17_S0.5701.00
35_L58_A0.5691.00
54_T58_A0.5671.00
32_L44_P0.5591.00
48_M52_Q0.5481.00
13_T17_S0.5461.00
16_S20_A0.5331.00
11_S16_S0.5261.00
66_L70_N0.5251.00
10_T16_S0.5191.00
45_L50_N0.5171.00
22_S26_L0.5171.00
32_L63_V0.5091.00
8_S12_S0.5031.00
9_T14_S0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2lc5A 1 0.5733 2.2 0.9 Contact Map
1utaA 1 0.3733 2 0.902 Contact Map
1vt0M 4 0.8533 1.4 0.911 Contact Map
1dd3A 6 0.36 1.3 0.912 Contact Map
2z6gA 1 0 1.3 0.912 Contact Map
3si5X 1 0.24 1.2 0.915 Contact Map
1dd4C 7 0.36 1.2 0.915 Contact Map
4qdyA 2 0 1.1 0.915 Contact Map
2jgqA 2 0.5067 1.1 0.915 Contact Map
2jojA 1 0.56 1.1 0.915 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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