GREMLIN Database
Phage_T7_tail - Phage T7 tail fibre protein
PFAM: PF03906 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 157 (144)
Sequences: 1379 (1110)
Seq/√Len: 92.5
META: 0.909

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
136_P147_Y3.7001.00
36_V65_A3.1331.00
143_V148_V2.9281.00
81_D94_D2.9221.00
33_K72_D2.8941.00
135_D140_Q2.8321.00
19_T56_T2.6701.00
140_Q144_T2.6621.00
145_K149_D2.5641.00
31_D102_Y2.4961.00
62_A65_A2.2031.00
133_V142_A2.1061.00
90_E94_D2.0161.00
127_N134_A1.9401.00
14_D17_T1.9211.00
120_D131_T1.9191.00
31_D74_P1.9131.00
135_D146_N1.8861.00
29_T49_F1.8671.00
140_Q146_N1.8281.00
25_P102_Y1.7691.00
18_T60_A1.7351.00
125_A130_I1.7051.00
20_F67_I1.6521.00
98_L102_Y1.6341.00
101_L105_Q1.6231.00
139_A146_N1.5941.00
41_K46_D1.5921.00
122_N129_R1.5851.00
29_T52_A1.5491.00
22_F26_Y1.5341.00
41_K47_Y1.5261.00
10_T68_R1.5231.00
124_D132_N1.5171.00
139_A149_D1.4781.00
57_F61_P1.4731.00
75_T103_L1.4701.00
147_Y150_T1.4661.00
78_R101_L1.4501.00
22_F49_F1.4220.99
136_P145_K1.4070.99
37_D65_A1.3610.99
34_V55_I1.3040.99
78_R97_F1.2800.99
118_D131_T1.2730.99
49_F52_A1.2600.99
129_R141_D1.2240.98
130_I133_V1.1990.98
18_T56_T1.1920.98
107_A111_A1.1740.98
89_T92_D1.1710.98
35_T68_R1.1620.98
78_R96_N1.1580.98
117_L128_K1.1420.97
81_D90_E1.1380.97
21_S54_T1.1360.97
28_D31_D1.1180.97
123_W128_K1.1050.97
35_T70_R1.0890.96
125_A133_V1.0880.96
115_L123_W1.0820.96
35_T40_V1.0800.96
9_V23_T1.0760.96
97_F100_N1.0720.96
79_L95_T1.0670.96
146_N150_T1.0660.96
123_W130_I1.0660.96
84_D89_T1.0540.96
84_D88_L1.0490.96
41_K44_T1.0490.96
50_A56_T1.0460.96
49_F55_I1.0400.95
15_G63_N1.0380.95
13_G20_F1.0350.95
13_G60_A1.0300.95
129_R137_T1.0290.95
33_K70_R1.0190.95
73_T106_E1.0130.95
78_R98_L1.0110.95
123_W126_Q1.0070.95
31_D79_L1.0050.94
19_T50_A0.9990.94
136_P148_V0.9700.93
137_T147_Y0.9650.93
146_N149_D0.9630.93
122_N131_T0.9600.93
32_V49_F0.9530.93
80_V95_T0.9290.92
82_F96_N0.9170.91
130_I142_A0.9100.91
99_Q106_E0.9080.91
128_K132_N0.8990.90
73_T99_Q0.8830.90
57_F60_A0.8700.89
36_V67_I0.8650.89
19_T54_T0.8610.88
135_D148_V0.8600.88
88_L93_L0.8560.88
141_D145_K0.8500.88
57_F67_I0.8290.87
100_N105_Q0.8200.86
26_Y29_T0.8170.86
118_D122_N0.8160.86
42_T46_D0.8100.85
61_P65_A0.8050.85
137_T149_D0.7990.84
135_D147_Y0.7880.84
141_D144_T0.7840.83
34_V47_Y0.7820.83
13_G61_P0.7800.83
138_D141_D0.7650.82
89_T94_D0.7590.81
122_N125_A0.7590.81
128_K134_A0.7580.81
51_N54_T0.7540.81
73_T102_Y0.7510.81
139_A144_T0.7450.80
124_D131_T0.7430.80
134_A137_T0.7420.80
110_L114_S0.7420.80
136_P143_V0.7410.80
80_V97_F0.7390.80
43_L47_Y0.7320.79
125_A142_A0.7240.78
110_L113_D0.7210.78
7_S11_Y0.7190.78
135_D142_A0.7120.77
136_P141_D0.7110.77
104_A107_A0.7090.77
24_F32_V0.7090.77
82_F97_F0.7070.76
117_L121_G0.7040.76
36_V41_K0.7020.76
130_I141_D0.6980.76
143_V149_D0.6920.75
121_G128_K0.6860.74
41_K57_F0.6850.74
7_S10_T0.6840.74
13_G63_N0.6800.74
93_L106_E0.6790.74
92_D96_N0.6760.73
140_Q143_V0.6740.73
133_V136_P0.6730.73
139_A150_T0.6660.72
27_L31_D0.6500.70
8_Y68_R0.6450.70
103_L108_I0.6410.69
97_F101_L0.6410.69
40_V43_L0.6360.69
129_R138_D0.6340.68
40_V47_Y0.6340.68
112_A126_Q0.6320.68
15_G61_P0.6270.68
43_L46_D0.6260.67
134_A141_D0.6260.67
57_F69_I0.6240.67
137_T141_D0.6230.67
17_T20_F0.6210.67
96_N103_L0.6190.67
125_A128_K0.6160.66
73_T92_D0.6090.65
110_L116_G0.6060.65
84_D87_V0.5990.64
37_D41_K0.5990.64
91_S95_T0.5980.64
140_Q149_D0.5980.64
135_D149_D0.5970.64
13_G67_I0.5950.64
38_G41_K0.5880.63
111_A114_S0.5880.63
43_L48_T0.5880.63
74_P100_N0.5870.62
127_N132_N0.5830.62
34_V69_I0.5820.62
51_N56_T0.5720.60
125_A132_N0.5720.60
18_T59_T0.5700.60
129_R136_P0.5690.60
112_A116_G0.5660.60
22_F25_P0.5660.60
130_I135_D0.5650.60
82_F100_N0.5620.59
74_P79_L0.5610.59
132_N139_A0.5560.58
117_L120_D0.5550.58
36_V61_P0.5540.58
134_A140_Q0.5510.58
13_G62_A0.5460.57
87_V90_E0.5440.57
41_K48_T0.5410.56
115_L130_I0.5380.56
144_T148_V0.5360.56
82_F94_D0.5350.55
84_D91_S0.5340.55
22_F97_F0.5310.55
115_L118_D0.5300.55
31_D73_T0.5230.54
13_G66_A0.5190.53
135_D139_A0.5180.53
139_A147_Y0.5180.53
143_V147_Y0.5160.53
86_S92_D0.5160.53
92_D95_T0.5150.53
138_D143_V0.5150.53
16_S21_S0.5150.53
144_T147_Y0.5110.52
119_A125_A0.5100.52
84_D92_D0.5100.52
11_Y22_F0.5090.52
75_T108_I0.5090.52
48_T58_T0.5070.52
133_V143_V0.5060.51
130_I137_T0.5050.51
22_F75_T0.5030.51
143_V146_N0.5030.51
71_R106_E0.5000.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4lgoA 3 0.7197 80 0.892 Contact Map
3d9xA 3 0.4968 66.6 0.903 Contact Map
3emoC 3 0.1847 60.6 0.907 Contact Map
3wprA 3 0.9172 34.9 0.92 Contact Map
4usxA 3 0.1975 26.3 0.925 Contact Map
2yo2A 3 0.6879 17.5 0.931 Contact Map
3s6lA 4 0.5987 16.3 0.932 Contact Map
2d73A 2 0.535 14.6 0.933 Contact Map
2xqhA 3 0.5796 11.5 0.936 Contact Map
3wpaA 3 0.7898 11.5 0.936 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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