ArsP_1 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ArsP_1 - Predicted permease

PFAM:	PF03773	Sequences: HLGEALTFFLYDLLEILPLLLLGFFIAGLIQAFVPPERVRRYLGGKNKFLGVLLAALLGAVLPFCSCGVIPLFAGLLKKGAPLGAAFAFLIASPLLNPVAIVLTAGLLGWKFALARVVGGLLIAIVAGLLIGRLFRERELEDAVREAAEAGSAGLERKPSLRRRRAFAREAVKDWKKVWPYLLIGVLIAALIHGYVPEDFIASLFGGNSLLAVLLAALIGVPLYVCAAGEIPIAAALLAKGMSLGAALAFLMAGPALSLPELLILRKVLGPRLLAVFLGLVVVGAILAGLLFNF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	294 (288)
Sequences:	19624 (11865)
Seq/√Len:	699.2
META:	0.836

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
266_R	271_P	4.634	1.00
262_L	278_L	3.088	1.00
160_S	163_R	2.832	1.00
101_I	117_V	2.821	1.00
157_R	160_S	2.809	1.00
169_R	173_K	2.621	1.00
168_A	171_A	2.505	1.00
119_G	288_A	2.477	1.00
167_F	171_A	2.457	1.00
221_V	282_V	2.427	1.00
171_A	174_D	2.404	1.00
271_P	275_A	2.342	1.00
238_L	247_A	2.233	1.00
160_S	164_R	2.082	1.00
199_D	202_A	2.070	1.00
91_I	127_A	2.033	1.00
84_G	132_G	2.014	1.00
234_A	247_A	1.999	1.00
92_A	124_A	1.982	1.00
161_L	164_R	1.955	1.00
191_L	195_Y	1.951	1.00
235_A	239_A	1.940	1.00
275_A	279_G	1.922	1.00
168_A	172_V	1.898	1.00
199_D	203_S	1.894	1.00
123_I	284_G	1.886	1.00
272_R	276_V	1.864	1.00
47_N	50_L	1.856	1.00
114_L	118_V	1.853	1.00
159_P	162_R	1.848	1.00
38_R	41_R	1.843	1.00
52_V	88_A	1.835	1.00
159_P	163_R	1.824	1.00
156_E	159_P	1.797	1.00
42_Y	54_L	1.781	1.00
198_E	202_A	1.760	1.00
136_R	139_E	1.716	1.00
170_E	174_D	1.700	1.00
155_L	159_P	1.681	1.00
133_R	136_R	1.674	1.00
167_F	170_E	1.671	1.00
220_G	253_A	1.645	1.00
176_K	179_W	1.643	1.00
157_R	161_L	1.633	1.00
104_T	108_L	1.597	1.00
253_A	285_A	1.590	1.00
171_A	175_W	1.588	1.00
77_L	83_L	1.571	1.00
141_E	144_V	1.569	1.00
140_L	145_R	1.542	1.00
249_A	289_G	1.531	1.00
73_F	86_A	1.522	1.00
175_W	179_W	1.505	1.00
157_R	162_R	1.505	1.00
151_G	154_G	1.505	1.00
38_R	42_Y	1.503	1.00
112_F	244_L	1.490	1.00
56_A	125_I	1.478	1.00
103_L	231_I	1.475	1.00
217_A	249_A	1.466	1.00
173_K	176_K	1.463	1.00
169_R	174_D	1.458	1.00
200_F	204_L	1.455	1.00
243_S	246_A	1.452	1.00
156_E	160_S	1.451	1.00
162_R	165_R	1.439	1.00
208_N	211_L	1.439	1.00
266_R	274_L	1.436	1.00
163_R	166_A	1.434	1.00
127_A	280_L	1.431	1.00
82_P	85_A	1.419	1.00
115_A	292_F	1.404	1.00
9_F	190_A	1.383	1.00
50_L	54_L	1.375	1.00
155_L	158_K	1.374	1.00
262_L	274_L	1.361	1.00
142_D	145_R	1.355	1.00
170_E	173_K	1.353	1.00
87_F	131_I	1.350	1.00
167_F	174_D	1.348	1.00
211_L	214_L	1.343	1.00
122_L	126_V	1.340	1.00
217_A	286_I	1.334	1.00
158_K	161_L	1.319	1.00
214_L	286_I	1.312	1.00
111_K	244_L	1.307	1.00
158_K	162_R	1.306	1.00
167_F	175_W	1.302	1.00
211_L	215_L	1.296	1.00
70_I	264_I	1.295	1.00
214_L	218_L	1.291	1.00
139_E	142_D	1.288	1.00
216_A	220_G	1.284	1.00
172_V	175_W	1.281	1.00
285_A	288_A	1.280	1.00
88_A	128_G	1.280	1.00
110_W	114_L	1.272	1.00
213_V	249_A	1.271	1.00
132_G	135_F	1.271	1.00
105_A	113_A	1.270	1.00
180_P	184_I	1.266	1.00
221_V	262_L	1.254	1.00
105_A	110_W	1.249	1.00
287_L	291_L	1.248	1.00
279_G	283_V	1.243	1.00
125_I	129_L	1.243	1.00
162_R	166_A	1.243	1.00
35_P	38_R	1.241	1.00
217_A	282_V	1.207	1.00
149_E	152_S	1.206	1.00
136_R	276_V	1.206	1.00
166_A	170_E	1.201	1.00
17_L	21_L	1.197	1.00
192_I	196_V	1.193	1.00
184_I	187_L	1.190	1.00
20_L	24_F	1.188	1.00
101_I	113_A	1.185	1.00
56_A	88_A	1.184	1.00
168_A	175_W	1.166	1.00
45_G	48_K	1.159	1.00
74_A	268_V	1.157	1.00
174_D	177_K	1.156	1.00
284_G	288_A	1.147	1.00
49_F	53_L	1.145	1.00
48_K	51_G	1.141	1.00
161_L	165_R	1.140	1.00
140_L	143_A	1.139	1.00
126_V	130_L	1.139	1.00
14_L	18_P	1.137	1.00
64_F	72_L	1.137	1.00
169_R	172_V	1.137	1.00
56_A	121_L	1.135	1.00
263_L	266_R	1.128	1.00
274_L	278_L	1.122	1.00
213_V	293_N	1.122	1.00
44_G	47_N	1.113	1.00
51_G	85_A	1.112	1.00
170_E	175_W	1.108	1.00
124_A	128_G	1.099	1.00
18_P	22_L	1.097	1.00
142_D	146_E	1.093	1.00
115_A	119_G	1.087	1.00
37_E	40_R	1.081	1.00
209_S	212_A	1.075	1.00
139_E	272_R	1.069	1.00
129_L	132_G	1.068	1.00
102_V	106_G	1.066	1.00
46_K	50_L	1.062	1.00
60_A	121_L	1.057	1.00
160_S	165_R	1.051	1.00
155_L	160_S	1.048	1.00
207_G	210_L	1.039	1.00
156_E	162_R	1.039	1.00
150_A	153_A	1.035	1.00
36_P	40_R	1.035	1.00
50_L	53_L	1.034	1.00
135_F	138_R	1.028	1.00
285_A	289_G	1.027	1.00
190_A	194_G	1.018	1.00
276_V	280_L	1.014	1.00
282_V	286_I	1.006	1.00
175_W	178_V	1.005	1.00
53_L	125_I	0.999	1.00
198_E	240_K	0.997	1.00
95_L	120_G	0.991	1.00
236_A	240_K	0.990	1.00
245_G	289_G	0.989	1.00
286_I	290_L	0.989	1.00
158_K	163_R	0.986	1.00
104_T	116_R	0.985	1.00
248_L	292_F	0.980	1.00
112_F	248_L	0.976	1.00
156_E	161_L	0.974	1.00
193_H	198_E	0.970	1.00
144_V	147_A	0.963	1.00
52_V	84_G	0.961	1.00
45_G	49_F	0.960	1.00
130_L	280_L	0.956	1.00
132_G	136_R	0.951	1.00
129_L	133_R	0.950	1.00
168_A	173_K	0.940	1.00
167_F	172_V	0.933	1.00
123_I	288_A	0.931	1.00
210_L	214_L	0.930	1.00
46_K	51_G	0.922	1.00
134_L	276_V	0.915	1.00
283_V	287_L	0.913	1.00
141_E	145_R	0.912	1.00
245_G	293_N	0.909	1.00
55_A	88_A	0.909	1.00
218_L	222_P	0.908	1.00
13_L	17_L	0.908	1.00
148_A	151_G	0.905	1.00
123_I	127_A	0.899	1.00
135_F	139_E	0.894	1.00
136_R	140_L	0.893	1.00
10_L	14_L	0.884	1.00
28_G	32_A	0.884	1.00
165_R	169_R	0.883	1.00
140_L	144_V	0.878	1.00
133_R	137_E	0.869	1.00
88_A	92_A	0.868	1.00
53_L	57_L	0.868	1.00
213_V	290_L	0.862	1.00
149_E	154_G	0.859	1.00
185_G	189_A	0.849	1.00
159_P	164_R	0.847	1.00
217_A	253_A	0.844	1.00
83_L	87_F	0.843	1.00
261_E	265_L	0.842	1.00
155_L	162_R	0.841	1.00
172_V	176_K	0.836	1.00
57_L	61_V	0.834	1.00
150_A	154_G	0.831	1.00
145_R	148_A	0.831	1.00
206_G	209_S	0.831	1.00
147_A	150_A	0.828	1.00
74_A	78_K	0.825	1.00
124_A	127_A	0.824	1.00
166_A	169_R	0.822	1.00
142_D	270_G	0.819	1.00
19_L	23_G	0.819	1.00
270_G	274_L	0.816	1.00
200_F	203_S	0.814	1.00
9_F	187_L	0.814	1.00
143_A	146_E	0.814	1.00
48_K	52_V	0.814	1.00
281_V	285_A	0.808	1.00
147_A	152_S	0.808	1.00
14_L	17_L	0.808	1.00
7_T	10_L	0.806	1.00
12_D	15_E	0.804	1.00
49_F	52_V	0.804	1.00
269_L	273_L	0.803	1.00
86_A	269_L	0.802	1.00
157_R	163_R	0.799	1.00
249_A	253_A	0.794	1.00
155_L	161_L	0.793	1.00
225_V	250_F	0.787	1.00
207_G	211_L	0.785	1.00
155_L	163_R	0.784	1.00
187_L	191_L	0.783	1.00
287_L	290_L	0.782	1.00
168_A	174_D	0.780	1.00
37_E	41_R	0.778	1.00
259_L	263_L	0.777	1.00
192_I	236_A	0.776	1.00
276_V	279_G	0.775	1.00
114_L	117_V	0.775	1.00
171_A	177_K	0.774	1.00
77_L	86_A	0.773	1.00
41_R	44_G	0.769	1.00
139_E	143_A	0.768	1.00
160_S	166_A	0.765	1.00
138_R	141_E	0.765	1.00
275_A	278_L	0.763	1.00
213_V	286_I	0.755	1.00
231_I	252_M	0.755	1.00
59_G	92_A	0.754	1.00
138_R	142_D	0.751	1.00
158_K	166_A	0.750	1.00
238_L	244_L	0.750	1.00
130_L	134_L	0.747	1.00
174_D	178_V	0.747	1.00
187_L	190_A	0.739	1.00
182_L	185_G	0.736	1.00
257_L	262_L	0.735	1.00
171_A	178_V	0.732	1.00
96_L	121_L	0.732	1.00
131_I	134_L	0.732	1.00
60_A	96_L	0.732	1.00
103_L	107_L	0.731	1.00
117_V	121_L	0.730	1.00
157_R	166_A	0.727	1.00
76_L	81_A	0.723	1.00
146_E	149_E	0.720	1.00
29_L	33_F	0.715	1.00
131_I	135_F	0.713	1.00
6_L	9_F	0.712	1.00
21_L	25_F	0.712	1.00
108_L	238_L	0.712	1.00
196_V	200_F	0.709	1.00
46_K	49_F	0.709	1.00
146_E	150_A	0.709	1.00
118_V	122_L	0.708	1.00
75_G	78_K	0.706	1.00
256_A	281_V	0.706	1.00
148_A	154_G	0.706	1.00
53_L	56_A	0.705	1.00
28_G	171_A	0.704	1.00
149_E	153_A	0.702	1.00
213_V	289_G	0.698	1.00
111_K	115_A	0.695	1.00
237_L	241_G	0.694	1.00
183_L	187_L	0.693	1.00
156_E	164_R	0.693	1.00
159_P	166_A	0.692	1.00
143_A	147_A	0.691	1.00
167_F	173_K	0.691	1.00
272_R	275_A	0.688	1.00
263_L	267_K	0.686	1.00
265_L	274_L	0.684	1.00
30_I	34_V	0.684	1.00
16_I	20_L	0.684	1.00
40_R	79_K	0.682	1.00
96_L	101_I	0.676	1.00
49_F	129_L	0.676	1.00
212_A	246_A	0.674	1.00
210_L	290_L	0.670	1.00
280_L	284_G	0.668	1.00
135_F	272_R	0.662	1.00
29_L	167_F	0.659	1.00
55_A	85_A	0.655	1.00
155_L	164_R	0.655	1.00
240_K	244_L	0.654	1.00
84_G	128_G	0.651	1.00
119_G	123_I	0.651	1.00
6_L	10_L	0.651	1.00
31_Q	36_P	0.651	1.00
24_F	28_G	0.650	1.00
208_N	212_A	0.649	1.00
48_K	132_G	0.645	1.00
109_G	113_A	0.642	1.00
23_G	27_A	0.642	1.00
97_N	100_A	0.642	1.00
242_M	247_A	0.641	1.00
16_I	19_L	0.639	1.00
205_F	242_M	0.639	1.00
225_V	228_A	0.639	1.00
89_F	93_S	0.639	1.00
217_A	220_G	0.639	1.00
253_A	282_V	0.638	1.00
267_K	271_P	0.637	1.00
73_F	77_L	0.637	1.00
139_E	144_V	0.637	1.00
25_F	28_G	0.633	1.00
111_K	114_L	0.628	1.00
126_V	284_G	0.628	1.00
18_P	21_L	0.627	1.00
125_I	128_G	0.626	1.00
108_L	235_A	0.625	1.00
51_G	55_A	0.623	1.00
248_L	252_M	0.621	1.00
113_A	117_V	0.620	1.00
8_F	11_Y	0.620	1.00
112_F	238_L	0.619	1.00
197_P	200_F	0.618	1.00
69_V	93_S	0.618	1.00
25_F	29_L	0.616	1.00
157_R	164_R	0.615	1.00
34_V	39_V	0.614	1.00
70_I	261_E	0.613	1.00
52_V	55_A	0.612	1.00
7_T	14_L	0.611	1.00
100_A	228_A	0.608	1.00
116_R	255_P	0.608	1.00
52_V	128_G	0.605	1.00
242_M	246_A	0.605	1.00
83_L	273_L	0.604	1.00
253_A	281_V	0.601	1.00
19_L	24_F	0.600	1.00
158_K	164_R	0.600	1.00
174_D	179_W	0.598	1.00
136_R	144_V	0.598	1.00
170_E	177_K	0.597	1.00
39_V	42_Y	0.595	1.00
83_L	135_F	0.594	1.00
273_L	276_V	0.593	1.00
207_G	243_S	0.588	1.00
27_A	30_I	0.587	1.00
56_A	124_A	0.583	1.00
127_A	131_I	0.582	1.00
83_L	131_I	0.581	1.00
29_L	32_A	0.580	1.00
182_L	186_V	0.580	1.00
289_G	293_N	0.579	1.00
177_K	180_P	0.577	1.00
164_R	167_F	0.577	1.00
75_G	79_K	0.574	1.00
135_F	140_L	0.572	1.00
226_C	250_F	0.571	1.00
7_T	11_Y	0.570	1.00
66_S	70_I	0.568	1.00
257_L	278_L	0.567	1.00
22_L	26_I	0.567	1.00
33_F	161_L	0.564	1.00
157_R	165_R	0.563	1.00
148_A	153_A	0.563	1.00
225_V	229_G	0.561	1.00
68_G	72_L	0.561	1.00
126_V	129_L	0.561	1.00
250_F	254_G	0.559	1.00
22_L	25_F	0.558	1.00
101_I	105_A	0.557	1.00
161_L	166_A	0.557	1.00
15_E	19_L	0.556	1.00
74_A	264_I	0.548	1.00
24_F	178_V	0.546	1.00
26_I	72_L	0.546	1.00
201_I	242_M	0.545	1.00
73_F	90_L	0.540	1.00
31_Q	79_K	0.538	1.00
205_F	208_N	0.536	1.00
136_R	146_E	0.536	1.00
249_A	286_I	0.534	1.00
154_G	157_R	0.532	1.00
181_Y	184_I	0.531	1.00
100_A	227_A	0.528	1.00
164_R	168_A	0.527	1.00
163_R	167_F	0.526	1.00
121_L	125_I	0.524	1.00
212_A	215_L	0.523	1.00
60_A	101_I	0.521	1.00
156_E	163_R	0.521	1.00
186_V	189_A	0.521	1.00
112_F	292_F	0.520	1.00
206_G	211_L	0.519	1.00
156_E	166_A	0.518	1.00
35_P	39_V	0.517	1.00
144_V	148_A	0.516	1.00
231_I	235_A	0.516	1.00
188_I	233_I	0.516	1.00
99_V	103_L	0.514	0.99
131_I	277_F	0.513	0.99
138_R	272_R	0.511	0.99
258_S	261_E	0.511	0.99
32_A	35_P	0.511	0.99
193_H	236_A	0.508	0.99
40_R	43_L	0.506	0.99
107_L	235_A	0.504	0.99
20_L	23_G	0.503	0.99
13_L	183_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pd6A	3	0.9218	49.5	0.94	Contact Map
1pw4A	1	0.915	29.9	0.947	Contact Map
3zojA	3	0.4626	23.6	0.949	Contact Map
4r1iA	2	0.932	21.9	0.95	Contact Map
3llqA	3	0.3673	20.4	0.951	Contact Map
2b6oA	6	0.5034	17.4	0.952	Contact Map
3qe7A	2	0.4626	14.8	0.954	Contact Map
3zuxA	1	0.4592	12.9	0.955	Contact Map
4j05A	3	0.4966	11.3	0.956	Contact Map
3o7qA	1	0.898	11.2	0.956	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0094 seconds.