GREMLIN Database
FliL - Flagellar basal body-associated protein FliL
PFAM: PF03748 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 103 (98)
Sequences: 21721 (15034)
Seq/√Len: 1518.7
META: 0.873

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
56_K73_E3.2741.00
48_A77_R2.7011.00
54_S67_K2.2581.00
3_P28_A2.0971.00
24_K99_E2.0321.00
57_T60_D2.0181.00
52_L77_R1.9431.00
26_S99_E1.9311.00
75_L79_N1.8841.00
56_K60_D1.7731.00
47_D71_R1.7691.00
30_E94_D1.7111.00
45_I78_I1.7021.00
49_I74_L1.6781.00
47_D51_T1.6751.00
41_H44_R1.6481.00
8_F46_R1.6091.00
63_T66_G1.5861.00
35_E38_E1.5091.00
77_R80_E1.4901.00
21_R58_A1.4651.00
34_E37_A1.4101.00
42_M46_R1.4061.00
29_L78_I1.3971.00
33_D36_V1.3761.00
49_I78_I1.3701.00
10_V23_L1.3541.00
25_V53_L1.3411.00
36_V39_E1.2931.00
72_E76_E1.2841.00
30_E44_R1.2801.00
52_L56_K1.2711.00
74_L95_V1.2691.00
75_L95_V1.2391.00
9_V24_K1.2281.00
52_L73_E1.2071.00
3_P98_T1.2041.00
58_A62_S1.1991.00
75_L94_D1.1951.00
51_T68_E1.1611.00
53_L74_L1.1581.00
26_S98_T1.1581.00
34_E38_E1.1561.00
68_E72_E1.1521.00
28_A43_P1.1461.00
68_E71_R1.1341.00
76_E80_E1.1101.00
32_D93_E1.1021.00
30_E96_Y1.0881.00
2_V31_V1.0721.00
72_E75_L1.0521.00
2_V37_A1.0361.00
48_A52_L1.0321.00
30_E93_E1.0251.00
8_F49_I1.0221.00
79_N92_V1.0181.00
71_R97_F1.0181.00
69_R73_E1.0021.00
58_A102_V0.9791.00
2_V42_M0.9711.00
29_L92_V0.9681.00
35_E39_E0.9631.00
48_A81_V0.9511.00
5_D42_M0.9341.00
33_D37_A0.9301.00
3_P26_S0.9281.00
55_S64_P0.9201.00
6_P26_S0.9111.00
27_V97_F0.9101.00
97_F100_F0.9051.00
71_R94_D0.9011.00
23_L100_F0.8971.00
60_D69_R0.8791.00
73_E77_R0.8771.00
69_R72_E0.8631.00
61_L102_V0.8601.00
61_L70_L0.8491.00
28_A98_T0.8391.00
65_E69_R0.8231.00
27_V49_I0.8151.00
47_D96_Y0.8041.00
56_K61_L0.8011.00
76_E79_N0.7991.00
64_P68_E0.7951.00
4_L45_I0.7931.00
11_N22_Y0.7801.00
66_G69_R0.7751.00
44_R94_D0.7681.00
53_L70_L0.7681.00
8_F50_L0.7561.00
51_T71_R0.7531.00
52_L74_L0.7501.00
79_N90_G0.7471.00
46_R50_L0.7451.00
10_V50_L0.7361.00
32_D35_E0.7351.00
51_T77_R0.7351.00
50_L54_S0.7331.00
32_D36_V0.7281.00
31_V36_V0.7201.00
59_E62_S0.7171.00
15_A18_G0.7141.00
31_V37_A0.7111.00
52_L70_L0.7111.00
12_L58_A0.6961.00
6_P24_K0.6881.00
48_A80_E0.6741.00
88_G91_K0.6721.00
75_L92_V0.6701.00
87_A90_G0.6641.00
78_I92_V0.6561.00
44_R96_Y0.6421.00
60_D66_G0.6381.00
9_V22_Y0.6361.00
49_I53_L0.6331.00
61_L66_G0.6321.00
82_L90_G0.6261.00
29_L95_V0.6221.00
47_D50_L0.6141.00
74_L78_I0.6121.00
3_P6_P0.6051.00
44_R81_V0.6051.00
65_E68_E0.6041.00
79_N91_K0.6021.00
23_L61_L0.5981.00
51_T67_K0.5971.00
44_R48_A0.5941.00
11_N54_S0.5911.00
32_D39_E0.5901.00
27_V95_V0.5861.00
46_R98_T0.5831.00
25_V100_F0.5821.00
4_L46_R0.5731.00
4_L29_L0.5551.00
48_A51_T0.5281.00
33_D39_E0.5271.00
83_G86_K0.5261.00
8_F12_L0.5251.00
48_A78_I0.5201.00
16_D21_R0.5191.00
31_V93_E0.5161.00
23_L53_L0.5121.00
36_V91_K0.5071.00
10_V53_L0.5041.00
55_S73_E0.5021.00
79_N82_L0.5011.00
4_L42_M0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bk6A 3 0.9223 14.3 0.851 Contact Map
1winA 1 0.9223 11 0.858 Contact Map
2rpbA 1 0.9223 6 0.874 Contact Map
4fvgA 2 0.9126 5.3 0.877 Contact Map
3k44A 1 0.5534 4.8 0.88 Contact Map
1xdxA 2 0.6893 3 0.891 Contact Map
4w23B 1 0.8835 3 0.891 Contact Map
1ygtA 2 0.6408 2.9 0.892 Contact Map
3j20A 1 0.8641 2.8 0.893 Contact Map
3zey0 1 0.8835 2.8 0.894 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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