GREMLIN Database
UPF0182 - Uncharacterised protein family (UPF0182)
PFAM: PF03699 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 757 (751)
Sequences: 6385 (4450)
Seq/√Len: 162.4
META: 0.804

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
597_T620_K4.7431.00
600_V608_I4.3071.00
549_R590_D4.1021.00
298_E302_E3.9871.00
620_K624_E3.6661.00
120_F135_V3.5081.00
521_R530_K3.3651.00
543_P550_L3.3211.00
546_V628_D3.3061.00
192_A247_L3.2481.00
625_M633_L3.2411.00
483_T593_D3.1701.00
528_V554_V3.1631.00
367_D540_D3.0871.00
113_L610_T3.0521.00
367_D452_E3.0471.00
450_F484_G3.0381.00
459_I506_I2.9991.00
227_A276_Y2.9961.00
135_V560_S2.9861.00
126_I299_R2.9521.00
220_A225_V2.8911.00
601_F622_L2.8591.00
306_A563_Y2.8331.00
188_S249_N2.8281.00
354_L428_F2.8131.00
600_V612_R2.7631.00
22_T500_R2.7371.00
531_I596_V2.7111.00
206_R233_W2.6851.00
384_A543_P2.6731.00
535_L556_A2.6691.00
419_E427_V2.6521.00
118_V613_K2.6421.00
314_E722_K2.5951.00
463_K513_T2.5361.00
719_N722_K2.5261.00
118_V610_T2.5261.00
21_Y25_L2.5251.00
117_A137_T2.4931.00
121_G130_D2.4871.00
489_G493_R2.4211.00
306_A311_D2.4201.00
397_Q402_E2.4051.00
281_Q289_E2.4011.00
447_R468_D2.3941.00
612_R621_P2.3931.00
214_R228_R2.3791.00
465_K479_T2.3541.00
333_A337_D2.3511.00
54_F151_L2.3051.00
196_L240_L2.2991.00
497_F520_Y2.2851.00
546_V551_Y2.2601.00
432_D436_V2.2591.00
486_V520_Y2.2461.00
544_V553_I2.2281.00
551_Y588_V2.2281.00
351_Y415_S2.2141.00
137_T141_L2.2081.00
284_V292_K2.1981.00
713_A723_L2.1871.00
300_N650_Y2.1761.00
537_Y587_A2.1571.00
536_T559_T2.1511.00
55_F97_A2.1431.00
412_V545_V2.1421.00
523_N526_E2.1321.00
196_L243_A2.0921.00
521_R526_E2.0911.00
384_A448_I2.0861.00
459_I516_S2.0781.00
134_Y210_L2.0751.00
218_T568_P2.0741.00
587_A598_F2.0731.00
622_L630_R2.0721.00
551_Y593_D2.0631.00
478_T481_E2.0421.00
152_L193_L2.0371.00
152_L197_L2.0331.00
539_S638_D2.0231.00
199_A240_L2.0191.00
148_L197_L2.0171.00
547_D628_D1.9971.00
39_R43_K1.9841.00
302_E306_A1.9751.00
203_W206_R1.9731.00
145_L201_G1.9671.00
57_I155_A1.9631.00
382_L412_V1.9591.00
155_A159_A1.9391.00
122_V306_A1.9201.00
560_S607_I1.9091.00
649_T661_R1.9061.00
532_A598_F1.8791.00
308_Y646_V1.8711.00
116_N613_K1.8711.00
51_G101_G1.8691.00
122_V131_I1.8621.00
282_R286_K1.8591.00
131_I563_Y1.8551.00
337_D376_E1.8521.00
692_E714_R1.8451.00
126_I225_V1.8391.00
28_D33_S1.8381.00
142_R208_E1.8281.00
244_V248_A1.8241.00
711_L725_V1.8151.00
203_W207_Y1.8001.00
484_G519_L1.7981.00
152_L194_F1.7981.00
447_R478_T1.7891.00
42_T112_L1.7861.00
305_R653_T1.7821.00
380_V414_M1.7671.00
279_L283_F1.7631.00
294_R656_Q1.7621.00
525_R529_Q1.7531.00
111_V115_L1.7461.00
647_Y725_V1.7391.00
501_F520_Y1.7391.00
711_L723_L1.7361.00
412_V543_P1.7211.00
240_L244_V1.6971.00
29_S484_G1.6931.00
414_M545_V1.6911.00
398_T659_Y1.6821.00
153_V157_L1.6651.00
544_V629_L1.6631.00
198_K202_Y1.6621.00
34_S617_G1.6481.00
553_I633_L1.6471.00
356_E704_R1.6451.00
122_V563_Y1.6281.00
448_I550_L1.6251.00
699_F711_L1.6131.00
610_T613_K1.6061.00
270_I274_G1.6051.00
528_V587_A1.6041.00
369_D632_H1.5921.00
588_V597_T1.5911.00
749_E752_Q1.5901.00
394_E397_Q1.5871.00
483_T595_T1.5851.00
163_Y186_H1.5821.00
298_E655_P1.5801.00
237_V241_L1.5751.00
294_R298_E1.5741.00
506_I518_I1.5741.00
414_M430_V1.5711.00
238_I268_V1.5701.00
50_F104_A1.5641.00
307_A563_Y1.5581.00
109_E113_L1.5441.00
534_F619_F1.5361.00
528_V537_Y1.5341.00
384_A550_L1.5291.00
276_Y280_V1.5291.00
553_I588_V1.5211.00
450_F519_L1.5201.00
22_T496_L1.5161.00
452_E540_D1.5161.00
581_I642_V1.5131.00
378_R419_E1.5101.00
138_L208_E1.5031.00
217_V221_G1.5011.00
61_N186_H1.4991.00
455_N523_N1.4981.00
227_A280_V1.4971.00
41_L45_G1.4821.00
299_R302_E1.4771.00
24_W28_D1.4701.00
268_V272_L1.4661.00
264_L268_V1.4631.00
352_R356_E1.4541.00
32_Y620_K1.4501.00
196_L200_V1.4431.00
601_F633_L1.4401.00
191_L246_F1.4371.00
684_K691_E1.4341.00
492_L496_L1.4331.00
416_P429_F1.4211.00
30_L531_I1.4171.00
193_L197_L1.4111.00
641_K678_P1.3971.00
608_I612_R1.3941.00
585_V608_I1.3921.00
141_L200_V1.3911.00
528_V589_V1.3911.00
61_N190_L1.3881.00
556_A587_A1.3841.00
628_D631_A1.3771.00
288_N291_A1.3751.00
315_E727_R1.3651.00
131_I135_V1.3641.00
644_A697_L1.3561.00
112_L116_N1.3531.00
117_A610_T1.3521.00
372_T377_Y1.3481.00
334_A691_E1.3481.00
24_W33_S1.3291.00
410_Y447_R1.3291.00
531_I598_F1.3291.00
303_A563_Y1.3281.00
378_R429_F1.3271.00
107_Q110_T1.3161.00
206_R229_L1.3141.00
362_D388_N1.3111.00
612_R617_G1.3081.00
39_R615_F1.3081.00
160_A187_L1.3071.00
19_G500_R1.3061.00
336_I339_I1.3051.00
145_L200_V1.3021.00
111_V140_F1.3001.00
524_I589_V1.2991.00
309_G312_D1.2961.00
57_I151_L1.2961.00
55_F59_Y1.2951.00
300_N567_Q1.2951.00
295_P298_E1.2941.00
587_A596_V1.2931.00
290_L294_R1.2911.00
735_Y743_R1.2911.00
471_S476_V1.2861.00
465_K477_Y1.2851.00
45_G49_V1.2831.00
60_L64_L1.2811.00
590_D593_D1.2781.00
110_T140_F1.2751.00
334_A684_K1.2741.00
482_G593_D1.2711.00
259_L263_G1.2701.00
549_R593_D1.2691.00
203_W236_A1.2661.00
627_A631_A1.2661.00
412_V430_V1.2621.00
22_T520_Y1.2551.00
326_A330_A1.2521.00
233_W236_A1.2501.00
537_Y556_A1.2471.00
537_Y554_V1.2401.00
714_R724_V1.2381.00
114_F140_F1.2381.00
537_Y598_F1.2361.00
194_F198_K1.2361.00
95_L99_F1.2341.00
57_I193_L1.2291.00
581_I639_L1.2251.00
32_Y531_I1.2221.00
141_L204_L1.2201.00
374_D440_D1.2161.00
377_Y682_I1.2151.00
280_V284_V1.2141.00
29_S450_F1.2141.00
23_D36_F1.2141.00
335_T338_N1.2131.00
13_L17_L1.2131.00
59_Y90_L1.2061.00
135_V607_I1.2051.00
21_Y496_L1.2021.00
38_T42_T1.1991.00
263_G267_V1.1941.00
445_R481_E1.1891.00
342_W347_L1.1881.00
603_P609_K1.1881.00
525_R554_V1.1861.00
622_L633_L1.1861.00
24_W37_W1.1801.00
388_N391_G1.1771.00
93_A97_A1.1761.00
714_R719_N1.1751.00
412_V443_V1.1721.00
110_T113_L1.1721.00
55_F94_L1.1721.00
508_L511_D1.1701.00
458_V519_L1.1661.00
181_P185_A1.1651.00
224_D228_R1.1611.00
64_L68_L1.1611.00
22_T497_F1.1581.00
682_I691_E1.1561.00
590_D595_T1.1551.00
487_P493_R1.1501.00
104_A143_F1.1501.00
603_P622_L1.1471.00
205_D232_L1.1471.00
327_A331_A1.1461.00
534_F618_L1.1431.00
467_F470_P1.1401.00
405_V464_Q1.1391.00
57_I61_N1.1391.00
366_V383_S1.1291.00
528_V598_F1.1281.00
226_H296_Y1.1271.00
209_L229_L1.1271.00
443_V545_V1.1241.00
430_V443_V1.1221.00
504_L508_L1.1221.00
157_L161_A1.1191.00
649_T664_L1.1181.00
652_M661_R1.1161.00
210_L220_A1.1161.00
559_T581_I1.1161.00
578_I581_I1.1161.00
221_G224_D1.1161.00
627_A630_R1.1151.00
621_P624_E1.1121.00
145_L204_L1.1111.00
248_A252_R1.1071.00
554_V589_V1.0961.00
94_L98_L1.0951.00
50_F147_W1.0951.00
63_L67_R1.0931.00
497_F518_I1.0921.00
199_A239_A1.0911.00
170_R173_R1.0901.00
118_V132_G1.0881.00
753_Q757_W1.0800.99
489_G514_S1.0780.99
112_L614_I1.0780.99
642_V646_V1.0760.99
37_W40_L1.0740.99
501_F518_I1.0720.99
59_Y63_L1.0710.99
129_K207_Y1.0690.99
65_A162_V1.0690.99
441_L545_V1.0660.99
637_E641_K1.0650.99
373_I376_E1.0640.99
149_L197_L1.0630.99
412_V550_L1.0620.99
463_K511_D1.0590.99
25_L493_R1.0590.99
214_R221_G1.0560.99
325_T328_D1.0550.99
588_V595_T1.0500.99
705_D738_M1.0480.99
299_R565_Y1.0480.99
309_G639_L1.0460.99
486_V497_F1.0450.99
198_K201_G1.0440.99
578_I642_V1.0440.99
670_E741_E1.0440.99
390_S397_Q1.0430.99
14_L17_L1.0430.99
275_I278_A1.0420.99
609_K612_R1.0420.99
423_E743_R1.0410.99
156_L194_F1.0390.99
200_V204_L1.0380.99
276_Y279_L1.0380.99
472_G475_N1.0340.99
117_A132_G1.0330.99
114_F137_T1.0320.99
133_F207_Y1.0310.99
495_L499_L1.0280.99
461_G479_T1.0270.99
14_L499_L1.0270.99
29_S33_S1.0270.99
222_Y280_V1.0240.99
681_V696_M1.0230.99
554_V587_A1.0230.99
223_T227_A1.0210.99
447_R481_E1.0200.99
216_V221_G1.0190.99
430_V437_S1.0180.99
231_A272_L1.0170.99
600_V603_P1.0170.99
461_G515_E1.0100.99
33_S37_W1.0100.99
551_Y597_T1.0090.99
600_V609_K1.0050.99
645_E648_A1.0040.99
152_L190_L0.9990.99
335_T683_M0.9970.99
484_G517_R0.9970.99
611_Y614_I0.9940.99
459_I512_I0.9920.99
192_A196_L0.9900.99
490_S493_R0.9900.99
400_V511_D0.9900.99
4_L8_V0.9890.99
644_A711_L0.9880.99
87_L91_G0.9880.99
144_L148_L0.9870.99
199_A236_A0.9870.99
202_Y235_L0.9860.99
310_L646_V0.9840.99
313_V723_L0.9830.99
317_P727_R0.9810.99
630_R717_G0.9780.99
275_I279_L0.9740.99
752_Q755_T0.9730.99
316_R724_V0.9730.99
281_Q286_K0.9720.99
260_I264_L0.9710.99
212_S215_G0.9710.99
149_L194_F0.9700.99
589_V596_V0.9680.99
612_R619_F0.9670.99
34_S38_T0.9650.99
741_E745_D0.9640.99
225_V296_Y0.9620.99
378_R418_N0.9600.99
477_Y657_V0.9600.99
54_F58_L0.9600.99
472_G730_K0.9590.99
3_L6_V0.9570.99
126_I210_L0.9560.99
692_E717_G0.9550.99
35_V618_L0.9540.99
683_M694_V0.9540.99
535_L619_F0.9530.99
118_V609_K0.9490.99
365_D540_D0.9480.99
20_F36_F0.9440.99
263_G266_V0.9430.99
195_L246_F0.9420.99
364_N453_L0.9410.99
662_E730_K0.9410.99
609_K613_K0.9410.99
329_L336_I0.9390.99
469_Y476_V0.9390.99
389_P456_D0.9390.99
290_L656_Q0.9370.99
380_V429_F0.9350.99
355_Q432_D0.9340.99
229_L233_W0.9330.98
58_L97_A0.9310.98
151_L155_A0.9300.98
297_I659_Y0.9290.98
5_V12_L0.9290.98
37_W41_L0.9270.98
235_L273_G0.9260.98
715_S721_G0.9260.98
663_D730_K0.9240.98
123_T128_G0.9220.98
295_P299_R0.9210.98
664_L702_R0.9210.98
202_Y239_A0.9210.98
220_A299_R0.9200.98
149_L198_K0.9190.98
186_H190_L0.9190.98
437_S443_V0.9180.98
303_A306_A0.9170.98
270_I275_I0.9150.98
680_Y695_L0.9140.98
462_T516_S0.9140.98
344_P677_E0.9120.98
547_D631_A0.9110.98
286_K289_E0.9110.98
392_L396_A0.9100.98
475_N657_V0.9100.98
414_M441_L0.9090.98
61_N64_L0.9080.98
120_F132_G0.9080.98
486_V518_I0.9070.98
399_W404_L0.9070.98
47_F101_G0.9050.98
132_G135_V0.9040.98
487_P517_R0.9040.98
131_I306_A0.9030.98
61_N163_Y0.9030.98
328_D331_A0.9030.98
695_L713_A0.9030.98
32_Y596_V0.9020.98
159_A190_L0.8960.98
352_R362_D0.8940.98
2_I5_V0.8940.98
279_L284_V0.8920.98
492_L495_L0.8920.98
484_G593_D0.8920.98
347_L381_M0.8910.98
156_L190_L0.8900.98
491_F495_L0.8900.98
30_L596_V0.8880.98
217_V300_N0.8860.98
509_S512_I0.8840.98
654_D657_V0.8810.98
332_N684_K0.8800.98
59_Y93_A0.8800.98
313_V711_L0.8800.98
267_V271_V0.8800.98
529_Q537_Y0.8770.98
243_A247_L0.8760.98
288_N511_D0.8740.98
403_H457_Y0.8720.98
602_D605_D0.8720.98
149_L153_V0.8720.98
142_R205_D0.8700.98
12_L16_A0.8690.98
694_V714_R0.8690.98
430_V435_P0.8670.98
252_R256_R0.8670.98
751_S755_T0.8670.98
110_T114_F0.8670.98
8_V12_L0.8610.97
245_L261_A0.8610.97
421_T425_L0.8580.97
696_M710_W0.8580.97
526_E530_K0.8580.97
345_R670_E0.8550.97
249_N252_R0.8540.97
201_G205_D0.8500.97
443_V446_P0.8480.97
448_I451_G0.8470.97
32_Y618_L0.8460.97
212_S224_D0.8450.97
43_K105_S0.8450.97
94_L97_A0.8450.97
602_D609_K0.8440.97
46_L111_V0.8430.97
598_F619_F0.8400.97
461_G487_P0.8380.97
48_L51_G0.8360.97
301_I305_R0.8350.97
666_Q702_R0.8350.97
307_A566_S0.8350.97
98_L102_L0.8340.97
42_T46_L0.8330.97
251_F254_R0.8310.97
668_P700_T0.8300.97
652_M664_L0.8290.97
132_G610_T0.8290.97
126_I220_A0.8290.97
56_L60_L0.8280.97
648_A666_Q0.8280.97
289_E659_Y0.8270.97
308_Y578_I0.8250.97
54_F100_A0.8240.97
692_E719_N0.8230.97
202_Y269_A0.8230.97
122_V130_D0.8220.97
91_G95_L0.8180.97
600_V619_F0.8170.97
211_Y214_R0.8170.97
669_T673_E0.8170.97
505_N511_D0.8160.96
482_G595_T0.8150.96
220_A565_Y0.8140.96
688_E714_R0.8130.96
668_P676_M0.8130.96
308_Y566_S0.8120.96
584_S605_D0.8110.96
657_V662_E0.8100.96
625_M630_R0.8100.96
402_E456_D0.8090.96
39_R42_T0.8080.96
120_F131_I0.8080.96
742_A746_Q0.8080.96
271_V275_I0.8070.96
735_Y740_I0.8040.96
494_R512_I0.8040.96
211_Y562_R0.8030.96
204_L207_Y0.8020.96
601_F608_I0.8010.96
84_R87_L0.7960.96
29_S486_V0.7950.96
140_F143_F0.7940.96
213_D218_T0.7930.96
404_L462_T0.7930.96
110_T143_F0.7930.96
192_A243_A0.7920.96
153_V194_F0.7900.96
127_F229_L0.7890.96
185_A249_N0.7890.96
236_A240_L0.7890.96
180_S183_A0.7880.96
460_V519_L0.7870.96
641_K677_E0.7860.96
637_E677_E0.7860.96
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150_A154_L0.7590.95
710_W728_F0.7580.95
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222_Y226_H0.7250.93
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715_S720_Y0.7230.93
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185_A250_A0.7060.92
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360_Y467_F0.7020.92
497_F500_R0.7000.92
64_L67_R0.6990.92
529_Q589_V0.6990.92
647_Y711_L0.6980.92
491_F494_R0.6960.92
53_L56_L0.6960.92
132_G136_F0.6950.92
405_V467_F0.6950.92
258_P265_L0.6950.92
300_N303_A0.6950.92
6_V9_V0.6940.92
239_A265_L0.6940.92
729_P732_K0.6910.92
47_F51_G0.6910.92
315_E653_T0.6900.92
403_H458_V0.6900.92
344_P637_E0.6880.91
60_L97_A0.6860.91
313_V647_Y0.6840.91
2_I6_V0.6830.91
308_Y642_V0.6790.91
716_D720_Y0.6790.91
712_A724_V0.6780.91
49_V56_L0.6780.91
61_N65_A0.6780.91
445_R592_Y0.6770.91
42_T45_G0.6770.91
281_Q293_E0.6760.91
551_Y590_D0.6740.91
524_I554_V0.6740.91
247_L250_A0.6730.91
312_D722_K0.6710.90
559_T578_I0.6710.90
84_R88_L0.6690.90
421_T427_V0.6690.90
266_V269_A0.6690.90
731_D735_Y0.6690.90
735_Y739_Q0.6680.90
202_Y265_L0.6680.90
471_S474_E0.6670.90
53_L57_I0.6670.90
743_R746_Q0.6650.90
329_L332_N0.6650.90
90_L94_L0.6650.90
254_R258_P0.6650.90
705_D733_L0.6630.90
400_V405_V0.6600.90
29_S519_L0.6600.90
464_Q511_D0.6600.90
470_P475_N0.6580.90
497_F501_F0.6580.90
667_V697_L0.6580.90
389_P402_E0.6570.89
111_V143_F0.6550.89
114_F117_A0.6540.89
111_V114_F0.6530.89
122_V303_A0.6530.89
669_T705_D0.6530.89
12_L15_S0.6520.89
555_D583_N0.6520.89
748_P751_S0.6510.89
169_I172_I0.6510.89
269_A273_G0.6500.89
684_K689_E0.6480.89
669_T675_P0.6470.89
155_A668_P0.6470.89
608_I619_F0.6460.89
225_V229_L0.6450.89
202_Y232_L0.6450.89
652_M660_N0.6430.88
381_M417_V0.6430.88
603_P623_S0.6430.88
241_L245_L0.6430.88
496_L530_K0.6420.88
330_A333_A0.6420.88
744_I757_W0.6410.88
518_I521_R0.6400.88
700_T706_N0.6400.88
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263_G270_I0.6390.88
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500_R521_R0.6370.88
64_L189_V0.6370.88
231_A235_L0.6360.88
623_S630_R0.6350.88
450_F517_R0.6350.88
38_T116_N0.6340.88
368_V415_S0.6340.88
235_L239_A0.6330.88
630_R633_L0.6330.88
58_L158_A0.6330.88
242_A261_A0.6330.88
54_F155_A0.6320.88
488_L491_F0.6320.88
195_L242_A0.6310.87
555_D586_K0.6300.87
175_R178_R0.6300.87
489_G515_E0.6290.87
663_D727_R0.6290.87
630_R718_E0.6280.87
28_D31_G0.6280.87
58_L155_A0.6260.87
50_F111_V0.6240.87
727_R730_K0.6240.87
481_E604_E0.6240.87
272_L276_Y0.6230.87
603_P612_R0.6230.87
35_V38_T0.6210.87
20_F40_L0.6210.87
685_L688_E0.6200.87
316_R688_E0.6200.87
359_T708_I0.6200.87
230_P234_I0.6170.86
611_Y619_F0.6160.86
701_P706_N0.6150.86
717_G720_Y0.6150.86
750_I754_L0.6150.86
189_V247_L0.6140.86
713_A717_G0.6140.86
124_D131_I0.6140.86
136_F607_I0.6140.86
5_V9_V0.6140.86
195_L262_V0.6130.86
379_Q417_V0.6130.86
146_G150_A0.6120.86
267_V272_L0.6120.86
119_P122_V0.6110.86
111_V137_T0.6110.86
129_K134_Y0.6110.86
480_Y484_G0.6100.86
191_L195_L0.6100.86
713_A720_Y0.6100.86
666_Q705_D0.6090.86
676_M697_L0.6090.86
10_L13_L0.6090.86
133_F138_L0.6090.86
481_E624_E0.6090.86
211_Y218_T0.6090.86
495_L498_A0.6090.86
47_F105_S0.6090.86
233_W237_V0.6090.86
189_V248_A0.6080.86
557_Y636_P0.6080.86
327_A330_A0.6070.85
14_L18_A0.6070.85
114_F528_V0.6070.85
227_A231_A0.6060.85
50_F143_F0.6060.85
374_D377_Y0.6060.85
231_A234_I0.6060.85
187_L191_L0.6060.85
29_S527_R0.6050.85
62_L158_A0.6040.85
460_V479_T0.6040.85
66_Y86_R0.6030.85
11_L14_L0.6020.85
260_I263_G0.6020.85
88_L91_G0.6020.85
727_R732_K0.6020.85
462_T512_I0.6020.85
183_A186_H0.6010.85
388_N453_L0.6010.85
291_A294_R0.6000.85
688_E692_E0.6000.85
76_R79_L0.6000.85
305_R310_L0.5990.85
637_E695_L0.5990.85
685_L724_V0.5990.85
546_V549_R0.5980.85
480_Y517_R0.5970.84
366_V381_M0.5970.84
357_I708_I0.5960.84
459_I518_I0.5960.84
264_L267_V0.5960.84
149_L152_L0.5960.84
221_G308_Y0.5950.84
294_R655_P0.5950.84
688_E691_E0.5950.84
399_W503_D0.5950.84
142_R145_L0.5930.84
115_L614_I0.5930.84
549_R595_T0.5930.84
544_V626_P0.5910.84
410_Y435_P0.5910.84
457_Y518_I0.5900.84
223_T281_Q0.5890.84
216_V659_Y0.5880.84
246_F258_P0.5880.84
358_R467_F0.5880.84
354_L425_L0.5860.83
198_K269_A0.5860.83
316_R687_G0.5860.83
80_L84_R0.5860.83
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135_V562_R0.5850.83
209_L212_S0.5840.83
133_F141_L0.5830.83
372_T631_A0.5830.83
378_R416_P0.5820.83
78_R82_E0.5820.83
623_S626_P0.5820.83
462_T465_K0.5820.83
118_V122_V0.5800.83
168_G173_R0.5800.83
58_L93_A0.5800.83
477_Y654_D0.5800.83
347_L350_T0.5790.83
473_D727_R0.5780.83
371_Y632_H0.5780.83
38_T614_I0.5780.83
553_I625_M0.5780.83
282_R292_K0.5770.82
197_L200_V0.5760.82
707_L712_A0.5760.82
717_G724_V0.5760.82
24_W36_F0.5750.82
286_K505_N0.5740.82
21_Y492_L0.5740.82
57_I148_L0.5730.82
716_D721_G0.5730.82
109_E112_L0.5730.82
129_K203_W0.5720.82
207_Y210_L0.5720.82
39_R46_L0.5710.82
504_L507_L0.5710.82
360_Y401_N0.5700.82
191_L250_A0.5690.82
348_L366_V0.5690.82
109_E116_N0.5690.82
445_R478_T0.5690.82
91_G94_L0.5690.82
221_G228_R0.5690.82
403_H456_D0.5680.81
745_D751_S0.5660.81
8_V16_A0.5660.81
398_T401_N0.5650.81
344_P365_D0.5650.81
400_V464_Q0.5650.81
59_Y97_A0.5630.81
49_V52_L0.5630.81
314_E724_V0.5630.81
123_T130_D0.5630.81
5_V8_V0.5620.81
15_S19_G0.5620.81
255_W259_L0.5620.81
113_L118_V0.5610.81
169_I173_R0.5610.81
622_L625_M0.5610.81
20_F37_W0.5610.81
90_L93_A0.5600.81
475_N730_K0.5600.81
601_F609_K0.5600.81
488_L506_I0.5600.81
156_L159_A0.5590.80
438_T441_L0.5580.80
559_T607_I0.5580.80
699_F725_V0.5570.80
51_G97_A0.5570.80
28_D48_L0.5560.80
305_R315_E0.5560.80
372_T376_E0.5560.80
611_Y615_F0.5550.80
535_L608_I0.5540.80
366_V413_V0.5530.80
199_A203_W0.5530.80
10_L14_L0.5530.80
159_A163_Y0.5530.80
271_V276_Y0.5520.80
62_L93_A0.5520.80
124_D128_G0.5520.80
392_L401_N0.5510.79
205_D208_E0.5510.79
496_L500_R0.5500.79
57_I159_A0.5500.79
198_K205_D0.5500.79
498_A507_L0.5500.79
234_I237_V0.5500.79
412_V441_L0.5500.79
651_H663_D0.5490.79
15_S502_G0.5490.79
736_G739_Q0.5490.79
662_E733_L0.5480.79
558_T608_I0.5470.79
224_D293_E0.5470.79
389_P392_L0.5470.79
278_A282_R0.5460.79
581_I584_S0.5460.79
237_V240_L0.5460.79
257_L260_I0.5460.79
733_L743_R0.5460.79
556_A598_F0.5460.79
312_D604_E0.5450.79
63_L90_L0.5450.79
133_F203_W0.5450.79
444_T548_G0.5450.79
373_I441_L0.5440.79
340_R540_D0.5440.79
214_R223_T0.5440.79
652_M730_K0.5440.79
558_T607_I0.5430.78
303_A307_A0.5430.78
141_L145_L0.5430.78
212_S221_G0.5430.78
738_M745_D0.5430.78
604_E689_E0.5420.78
641_K644_A0.5410.78
527_R596_V0.5410.78
633_L720_Y0.5400.78
279_L508_L0.5400.78
27_F531_I0.5380.78
752_Q757_W0.5370.78
668_P679_Y0.5360.78
537_Y618_L0.5360.78
63_L68_L0.5360.78
209_L232_L0.5360.78
120_F606_P0.5350.77
148_L200_V0.5340.77
23_D26_W0.5340.77
309_G602_D0.5320.77
366_V707_L0.5320.77
431_K436_V0.5310.77
626_P629_L0.5310.77
377_Y417_V0.5310.77
150_A157_L0.5310.77
339_I702_R0.5310.77
340_R343_D0.5310.77
741_E744_I0.5300.77
238_I242_A0.5300.77
498_A506_I0.5300.77
87_L106_G0.5290.77
49_V53_L0.5290.77
346_P349_D0.5290.77
22_T486_V0.5280.77
198_K235_L0.5280.77
444_T628_D0.5280.77
747_D750_I0.5280.77
17_L20_F0.5280.77
540_D637_E0.5270.76
195_L508_L0.5270.76
629_L633_L0.5260.76
168_G180_S0.5250.76
538_D557_Y0.5250.76
290_L511_D0.5250.76
584_S601_F0.5250.76
582_R602_D0.5240.76
342_W381_M0.5240.76
320_A732_K0.5240.76
257_L264_L0.5230.76
247_L251_F0.5220.76
161_A165_L0.5220.76
87_L90_L0.5220.76
314_E624_E0.5220.76
18_A499_L0.5210.76
565_Y700_T0.5210.76
491_F507_L0.5210.76
752_Q756_L0.5210.76
657_V730_K0.5210.76
310_L647_Y0.5210.76
202_Y209_L0.5200.75
155_A190_L0.5200.75
398_T402_E0.5200.75
53_L151_L0.5200.75
332_N691_E0.5190.75
215_G289_E0.5190.75
660_N742_A0.5190.75
365_D677_E0.5190.75
740_I744_I0.5190.75
242_A265_L0.5180.75
145_L149_L0.5180.75
390_S402_E0.5180.75
210_L299_R0.5180.75
641_K667_V0.5170.75
674_Q741_E0.5170.75
652_M662_E0.5160.75
487_P519_L0.5150.75
6_V19_G0.5150.75
234_I268_V0.5150.75
622_L627_A0.5140.75
62_L65_A0.5130.75
386_E451_G0.5130.75
97_A100_A0.5120.74
254_R257_L0.5120.74
290_L494_R0.5120.74
74_L77_Y0.5120.74
583_N586_K0.5120.74
396_A661_R0.5110.74
121_G547_D0.5110.74
646_V650_Y0.5110.74
410_Y469_Y0.5110.74
556_A601_F0.5100.74
17_L21_Y0.5100.74
373_I378_R0.5090.74
110_T137_T0.5090.74
9_V13_L0.5090.74
470_P662_E0.5090.74
137_T142_R0.5080.74
238_I272_L0.5080.74
282_R395_Q0.5070.74
641_K645_E0.5070.74
122_V302_E0.5070.74
727_R731_D0.5070.74
685_L714_R0.5070.74
55_F93_A0.5070.74
60_L193_L0.5060.74
227_A230_P0.5060.74
305_R313_V0.5060.74
313_V646_V0.5050.73
660_N754_L0.5040.73
706_N750_I0.5040.73
444_T549_R0.5040.73
484_G531_I0.5040.73
644_A667_V0.5040.73
11_L16_A0.5030.73
461_G517_R0.5030.73
468_D476_V0.5030.73
215_G398_T0.5030.73
124_D127_F0.5030.73
177_L180_S0.5020.73
488_L509_S0.5020.73
450_F458_V0.5020.73
741_E746_Q0.5010.73
382_L414_M0.5010.73
236_A239_A0.5010.73
66_Y89_L0.5010.73
26_W108_W0.5010.73
288_N513_T0.5000.73
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j5pB 3 0.2497 26.5 0.988 Contact Map
4yayA 1 0.3012 22.2 0.988 Contact Map
2a9hA 4 0.0964 19 0.988 Contact Map
3d31C 2 0.3012 13.5 0.989 Contact Map
3edyA 1 0.107 11.6 0.99 Contact Map
2zy9A 2 0.1651 11 0.99 Contact Map
2k1eA 3 0.103 9.5 0.99 Contact Map
2ih3C 4 0.0978 9.1 0.99 Contact Map
4nv5A 1 0.3421 9.1 0.99 Contact Map
3oufA 4 0.1057 8.2 0.99 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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